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1.
Background
With the recent introduction of laparoscopic partial hepatectomy and laparoscopic/open radiofrequency ablation for hepatocellular carcinoma (HCC), the role of preoperative laparoscopic staging may be expanded. The objective of this study was to determine the role of preoperative laparoscopy and laparoscopic ultrasonography (USG) in patients with HCC.Methods
From January 2001 to April 2007, a cohort of 122 consecutive patients with a diagnosis of potentially resectable HCC underwent staging laparoscopy with laparoscopic USG before performing a major laparotomy in a tertiary referral center. The patients' data were collected prospectively. We have retrospectively analyzed the effect of implementation of this staging technique in our center.Results
Preoperative laparoscopy and laparoscopic USG was successful in 119 patients (97.5%). Forty-four patients were found to be unresectable after laparoscopic staging, whereas 2 patients were found to be unresectable after exploratory laparotomy. The total number of patients who underwent curative liver resection was 73 (laparoscopic partial hepatectomy, 22 patients; open partial hepatectomy, 51 patients). The median hospital stay of the laparoscopic liver resection group was significantly shorter than that of the open resection group (8 vs 13 d; P = .002). Intraoperative treatment for patients with unresectable HCC, including local ablative therapy, or combined liver resection and local ablative therapy, was performed in 27 of 45 inoperable patients (60%) (laparoscopic approach, 8 patients; open approach, 19 patients). The median hospital stay of the laparoscopic treatment group was significantly shorter than for the open treatment group for patients with unresectable HCC (5 vs 7 d; P = .003). In this study, a laparoscopic treatment approach for HCC was performed in 25.2% of the study population.Conclusions
Laparoscopy and laparoscopic USG have a significant effect both on identifying surgically untreatable disease and in selecting the optimal treatment strategy. Some patients will benefit from a laparoscopic therapy approach. Therefore, it argues for more widespread use in laparoscopic staging procedures for patients with potentially resectable HCC. 相似文献2.
Staging laparoscopy in patients with extrahepatic biliary carcinoma. Analysis of 100 patients 总被引:16,自引:0,他引:16
OBJECTIVE: To evaluate the benefit of staging laparoscopy in patients with gallbladder cancer and hilar cholangiocarcinoma. SUMMARY BACKGROUND DATA: In patients with extrahepatic biliary carcinoma, unresectable disease is often found at the time of exploration despite extensive preoperative evaluation, thus resulting in unnecessary laparotomy. METHODS: From October 1997 to May 2001, 100 patients with potentially resectable gallbladder cancer (n = 44) and hilar cholangiocarcinoma (n = 56) were prospectively evaluated. All patients underwent staging laparoscopy followed by laparotomy if the tumor appeared resectable. Surgical findings, resectability rate, length of stay, and operative time were analyzed. RESULTS: Patients underwent multiple preoperative imaging tests, including computed tomography scan, ultrasound, magnetic resonance cholangiopancreatography, and direct cholangiography. Laparoscopy identified unresectable disease in 35 of 100 patients. In the 65 patients undergoing open exploration, 34 were found to have unresectable disease. Therefore, the overall accuracy for detecting unresectable disease was 51%. There was no difference in the accuracy of laparoscopy between patients with gallbladder cancer and hilar cholangiocarcinoma. Laparoscopy detected the majority of patients with peritoneal or liver metastases but failed to detect all locally advanced tumors. In patients undergoing biopsy only, laparoscopic identification of unresectable disease significantly reduced operative time and length of stay compared with patients undergoing laparotomy. The yield of laparoscopy was 48% in patients with gallbladder cancer (56% in those who did not undergo previous cholecystectomy), but only 25% in patients with hilar cholangiocarcinoma. However, in patients with locally advanced but potentially resectable hilar cholangiocarcinoma, the yield of laparoscopy was greater, 36% (12/33, T2/T3 tumors) versus 9% (2/23, T1 tumors). CONCLUSIONS: Laparoscopy identifies the majority of patients with unresectable hilar cholangiocarcinoma or gallbladder carcinoma, thereby reducing both the incidence of unnecessary laparotomy and the length of stay. The yield of laparoscopy is lower for hilar cholangiocarcinoma but can be improved by targeting patients at higher risk of occult unresectable disease. All patients with potentially resectable primary gallbladder cancer and patients with T2/T3 hilar cholangiocarcinoma should undergo staging laparoscopy before surgical exploration. 相似文献
3.
Lavonius MI Gullichsen R Salo S Sonninen P Ovaska J 《Surgical laparoscopy, endoscopy & percutaneous techniques》2002,12(2):77-81
In this study, we evaluated and compared the value of spiral computed tomography, transabdominal ultrasonography, laparoscopy, and laparoscopic ultrasonography in staging gastric cancer in 37 patients; there was a special interest in the additional information provided by laparoscopic ultrasonography. Although laparoscopy was unreliable or hindered by adhesions in 11% of the patients, the benefit of laparoscopy for staging was evident especially for the detection of peritoneal carcinomatosis that was missed by the other diagnostic modalities. Laparoscopic ultrasonography did not change the stage of the disease nor the decision whether to proceed with laparotomy for any of the patients. The decision whether to proceed with laparotomy was correctly predicted in 95% of the cases. 相似文献
4.
目的 :研究腹腔镜及腹腔镜超声检查在腹部恶性肿瘤术前应用的意义。方法 :将腹部恶性肿瘤6 0例随机分为 2组 ,A组术前使用腹腔镜及其超声检查了解肿瘤情况 ,并根据检查结果决定是否行开腹手术 ,B组直接行剖腹探查。结果 :A组术前使用腹腔镜及其超声检查的患者中 6例发现失去了手术时机 ,未再行手术治疗 ;2例在腹腔镜辅助下施行了姑息性手术 ;余者施行了根治性手术。B组直接行剖腹探查的患者中发现 5例病程较晚无手术价值而直接关腹 ;2例施行了姑息性手术 ;余者施行了根治性手术。结论 :腹部恶性肿瘤患者术前使用腹腔镜及其超声检查有助于了解病变的范围及分期 ,为制定合理的治疗方案提供了可靠依据 ,使患者免受不必要的创伤和打击 ,降低了手术并发症的发生率 ,减少了患者痛苦和医疗费用 相似文献
5.
6.
Michael Bau Mortensen Claus Fristrup Alan Ainsworth Henning Overgaard Nielsen Torsten Pless Claus Hovendal 《Surgical endoscopy》2011,25(3):804-812
Background
The combination of endoscopic and laparoscopic ultrasonography (EUS–LUS) is accurate for resectability assessment of patients with upper gastrointestinal cancer (UGIC). But neither the ability of EUS/LUS to predict long-term prognosis nor the potential impact on patient survival using this selection strategy has been investigated. This prospective, single-center study evaluated whether pretherapeutic EUS–LUS stratification related to the prognosis in UGIC patients and whether patient selection by this strategy provided a prognostic outcome comparable with survival data from the literature. 相似文献7.
Peroperative time-motion analysis of diagnostic laparoscopy with laparoscopic ultrasonography. 总被引:1,自引:0,他引:1
BACKGROUND: Advanced technology is being introduced rapidly into laparoscopic procedures, frequently without an accurate evaluation of its functioning. In this study, standardized time-motion analysis was applied to evaluate the peroperative surgical process and the technical equipment used in 18 cases of diagnostic laparoscopy with laparoscopic ultrasonography (DLLU). METHODS: The image through the laparoscope, the ultrasonograph and an overview of the operating theatre were recorded simultaneously. The time for each phase, efficient actions (e.g. identifying lesions by inspection, making an ultrasonogram or taking a biopsy) and limiting factors (e.g. technical problems, time spent waiting) were determined, and a current standard was defined. RESULTS: Of the actions performed, 52 per cent were qualified as efficient, 17 per cent were classified as time spent waiting for personnel, instruments were positioned in 13 per cent, and unnecessary instrument exchanges were involved in 10 per cent. The evaluation led to a significant reduction in delay times and resulted in design criteria for improved biopsy instruments. The current standard was calculated from the mean time and number of actions determined for each phase. CONCLUSION: This time-motion study provided detailed insight into the peroperative process of DLLU, leading to improvements in the surgical process and instruments used. The defined current standard will enable evaluation of the learning curve and new technologies. 相似文献
8.
Laparoscopy and laparoscopic ultrasonography avoid exploratory laparotomy in patients with hepatocellular carcinoma. 总被引:14,自引:0,他引:14
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OBJECTIVE: This prospective study evaluates the value of laparoscopy and laparoscopic ultrasonography (USG) in avoiding exploratory laparotomy in patients with hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA: Laparotomy and intraoperative USG is the gold standard to determine the resectability of HCC. No palliation can be offered to patients found to have unresectable disease, and the surgical exploration causes morbidity. METHODS: From June 1994 to June 1996, 110 of 370 patients (30%) with HCC were considered candidates for possible hepatic resection. Preoperative liver function was assessed using Child-Pugh grading and indocyanine green retention test. The extent of disease was evaluated with radiologic studies, including percutaneous USG, computerized tomography scan, and hepatic angiogram. Nineteen patients were excluded from the study because of previous upper abdominal surgery (n = 12), ruptured tumors (n = 4), refusal by patients (n = 2), and instrument failure (n = 1). Laparoscopy and laparoscopic USG was performed on 91 patients immediately before a planned laparotomy aiming at hepatic resection. Laparotomy was aborted when definite evidence of unresectable disease was found on laparoscopic examination. RESULTS: The median time required for laparoscopy and laparoscopic USG was 30 minutes (range, 10 to 120 minutes). Fifteen patients had evidence of unresectable disease on laparoscopic examination. Among the remaining 76 patients who underwent laparotomy, 9 had exploration only and 67 underwent hepatic resection. Thus, exploratory laparotomy was avoided in 63% of patients with unresectable disease. The laparoscopic examination failed to confirm unresectable disease more often when the tumor was >10 cm in diameter. The procedure accurately assessed the adequacy of the liver remnant and the presence of intrahepatic metastases, but it was less sensitive in determining the presence of tumor thrombi in major vascular structures and the extent of invasion of adjacent organs. When unresectable disease was detected without the need for a laparotomy, the postoperative recovery was faster, and the nonoperative treatment for the tumor could be initiated earlier. CONCLUSIONS: Laparoscopy with laparoscopic USG avoids unnecessary laparotomy in patients with HCC and should precede a planned laparotomy aiming at hepatic resection. 相似文献
9.
Background: Despite various preoperative imaging methods, unnecessary laparotomy is still quite common in upper gastrointestinal surgery. There have been some studies demonstrating the use of diagnostic laparoscopy and laparoscopic ultrasound in the detection of small peritoneal seedling and vascular encasement of major vessels respectively, and these are the findings often inadequately assessed by preoperative imaging. Objective: This is a study to evaluate the use of diagnostic laparoscopy and selective laparoscopic ultrasound in the management of upper gastrointestinal malignancy. Method: A prospective study was carried out during the period from January 1996 to December 1997. Patients with upper gastrointestinal malignancy underwent diagnostic laparoscopy and selective laparoscopic ultrasound before resection. The role of laparoscopic staging was evaluated according to the number of patients who avoided unnecessary laparotomy. Results: There were 159 patients of mean age 62.8 years diagnosed with upper gastrointestinal tumours during the study period. These patients had various upper gastrointestinal malignancies: gastric carcinoma (89), oesophageal carcinoma (27), hepatobiliary malignancy (26), peri‐ampullary carcinoma (15) and small bowel tumour (2). Routine diagnostic laparoscopy and selective laparoscopic ultrasound were carried out for these patients unless there were contraindications such as a history of previous upper gastrointestinal surgery or the patient required palliative procedure irrespective of resectability. There were 106 diagnostic laparoscopies and 42 laparoscopic ultrasounds performed. Unnecessary operations were avoided in 32 patients (30%) due to either diffuse carcinomatosis or locally advanced tumour with encasement of major vessels. The role of laparoscopic staging in avoiding unnecessary surgery was particularly pronounced in peri‐ampullary carcinoma (46%) and hepatobiliary malignancy (38%). Conclusion: In summary, diagnostic laparoscopy and selective laparoscopic ultrasound are useful in avoiding unnecessary laparotomy particularly in hepatobiliary and peri‐ampullary malignancy. 相似文献
10.
Lo CM Fan ST Liu CL Poon RT Lam CM Yuen WK Yeung C Wong J 《Journal of Hepato-Biliary-Pancreatic Surgery》2000,7(3):260-264
We reviewed our experience with preoperative determination of resectability in patients with hepatocel-lular carcinoma (HCC)
over the last 10 years, and evaluated the role of laparoscopy with laparoscopic ultrasonography (USG) since we instituted
this technique in June 1994. From January 1989 to December 1998, 500 of 1741 patients with HCC (28.7%) were considered suitable
for hepatic resection after preoperative assessment. Significantly more contrast-enhanced computed tomography (CT) scans and
fewer percutaneous USGs or hepatic arteriograms were performed in the 299 patients managed since June 1994 (group 2) than
in the 201 patients managed before then (group 1). One hundred and ninety-eight patients in group 2 (66%) underwent laparoscopy
with laparoscopic USG. Unresectable disease was found in 41 patients in group 1 (20.4%) (all at laparotomy), and in 68 patients
in group 2 (22.7%) (16 at laparotomy without laparoscopic examination, 31 at laparoscopic examination alone, and 21 at laparotomy
after an inconclusive laparoscopic examination) (P = 0.5). The most common features of unresectable disease were the presence of bilobar intrahepatic metastases and an inadequate
liver remnant with cirrhosis. The adoption of the laparoscopic examination after June 1994 improved the overall resection
rate at laparotomy in group 2 from 77.3% to 86.2%, which was better than that in group 1 (79.6%, P = 0.057). For patients with unresectable disease, the operation time and hospital stay were significantly shorter in group
2. The postoperative morbidity and mortality rates were 9.8% and 4.9%, respectively, in group 1, and 5.9% and 2.9% in group
2. There was no operative morbidity in the 31 patients who had unresectable disease detected by the laparoscopic examination
alone. Laparoscopy with laparoscopic USG avoids unnecessary laparotomy, and has a definite role in determining resectability
in patients with HCC.
Received for publication on Jan. 17, 2000; accepted on April 1, 2000 相似文献
11.
An accurate pretherapeutic assessment of resectability in patients with upper gastrointestinal malignancies (UGIM) is mandatory in order to choose the optimal treatment strategy. Endoscopic ultrasonography (EUS) has significantly reduced the need for exploratory laparotomy in patients with UGIM, but the pretherapeutic evaluation in about 10% of the patients is incomplete due to certain limitations of the EUS. We prospectively evaluated the use and results of diagnostic laparoscopy in patients with UGIM selected for this procedure by EUS.In six patients with incomplete EUS, laparoscopy demonstrated nonresectability in five patients and a resectable tumor in one patient, and laparoscopy thus filled the informational gap in all cases. In addition, laparoscopy confirmed nonresectability in ten patients in whom EUS had suggested nonresectability. By employing the combinated use of EUS and laparoscopy it seems possible to avoid a great number of futile laparoscopies, and it should also reduce the need for explorative laparotomies. Larger prospective studies have been initiated and might be able to confirm this. 相似文献
12.
目的:探讨腹腔镜技术在上消化道穿孔治疗中的应用价值。方法:选择2012年2月至2013年10月收治的46例行急诊手术治疗的上消化道穿孔患者,随机分为腹腔镜手术组与传统开腹手术组,每组23例。对比分析两组手术时间、切口长度、术中出血量、术后72 h引流情况、术后疼痛评分(Prince-Henry评分法)、体温恢复正常时间、首次下床时间、首次排气时间、住院时间、住院费用、并发症等指标。结果:与传统剖腹探查组相比,腹腔镜组手术切口短,术中出血少,术后胃肠功能恢复较快,住院时间短,并发症发生率低,手术费用两组差异无统计学意义。结论:腹腔镜手术治疗消化道穿孔具有明显优势,经验丰富的术者既可明确诊断,又可同时进行治疗,最大程度地减少了患者的创伤,是安全、可行的。 相似文献
13.
Staging of pancreatic and ampullary cancers for
resectability using laparoscopy with laparoscopic
ultrasound 总被引:5,自引:0,他引:5
Background: Cancers of the pancreas and periampullary region are rarely curable. We set out to determine the efficacy of laparoscopy
with laparoscopic ultrasound in the staging of pancreatic and ampullary malignancies for resectability. Methods: Between January
1994 and September 1999, we retrospectively reviewed the laparoscopic staging (LS) of tumors already deemed resectable by
standard radiologic criteria in 27 patients using laparoscopy with laparoscopic ultrasound (LUS). Patients found to be resectable
by LS evaluation underwent laparotomy (LA). We then compared the results of the LS and LA findings. Results: Of the 27 patients
evaluated, 17 were men and 10 were women. Their mean age was 66 years. Preoperative computerized tomography (CT) scans were
done in all 27 patients (100%), and transabdominal and endoscopic ultrasound (EUS) was done in 21 (78%). By LS, seven patients
(26%) were found to have unresectable disease. Two patients with mesenteric tumor infiltration (one with peritoneal implants,
and one with a visible liver metastasis) were judged to be unresectable by laparoscopy alone. LUS revealed that one patient
had portal vein (PV) occlusion and two had metastases to the lymph nodes or liver that were not revealed by preoperative studies
or laparoscopy alone. Among 20 patients (74%) deemed resectable by LS, two (10%) were found to be unresectable at LA, one
due to PV involvement and the other due to local tumor extension with superior mesenteric lymph node metastasis. Eighteen
of those in whom resection was attempted (90%) were resectable, with no unexpected findings of distant lymph node or hepatic
metastasis. Pathology examination showed that eight had regional metastases (44%). The sensitivity of LS in determining unresectability
was 77% (seven true positives and two false negatives). The negative predictive value (reflecting resectability) was 90%.
Laparoscopy alone had a sensitivity of 44%, with a negative predictive value of 78%. The sensitivity and positive predictive
value of LS was 100%, reflecting no false positive examinations. Conclusions: LS can effectively stage most patients and reliably
predict which of them will benefit from LA. Intervention for unresectable patients can then be limited to laparoscopic or
endoscopic bypass. The main limitation is that LS may underestimate PV and regional lymph node involvement. 相似文献
14.
Carcinoma of the pancreatic head and periampullary region. Tumor staging with laparoscopy and laparoscopic ultrasonography. 总被引:19,自引:4,他引:15
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OBJECTIVE: The authors performed a prospective evaluation of staging laparoscopy with laparoscopic ultrasonography in predicting surgical resectability in patients with carcinomas of the pancreatic head and periampullary region. SUMMARY BACKGROUND DATA: Pancreatic resection with curative intent is possible in a select minority of patients who have carcinomas of the pancreatic head and periampullary region. Patient selection is important to plan appropriate therapy and avoid unnecessary laparotomy in patients with unresectable disease. Laparoscopic ultrasonography is a novel technique that combines the proven benefits of staging laparoscopy with high resolution intraoperative ultrasound of the liver and pancreas, but which has yet to be evaluated critically in the staging of pancreatic malignancy. METHODS: A cohort of 40 consecutive patients referred to a tertiary referral center and with a diagnosis of potentially resectable pancreatic or periampullary cancer underwent staging laparoscopy with laparoscopic ultrasonography. The diagnostic accuracy of staging laparoscopy alone and in conjunction with laparoscopic ultrasonography was evaluated in predicting tumor resectability (absence of peritoneal or liver metastases; absence of malignant regional lymphadenopathy; tumor confined to pancreatic head or periampullary region). RESULTS: "Occult" metastatic lesions were demonstrated by staging laparoscopy in 14 patients (35%). Laparoscopic ultrasonography demonstrated factors confirming unresectable tumor in 23 patients (59%), provided staging information in addition to that of laparoscopy alone in 20 patients (53%), and changed the decision regarding tumor resectability in 10 patients (25%). Staging laparoscopy with laparoscopic ultrasonography was more specific and accurate in predicting tumor resectability than laparoscopy alone (88% and 89% versus 50% and 65%, respectively). CONCLUSIONS: Staging laparoscopy is indispensable in the detection of "occult" intra-abdominal metastases. Laparoscopic ultrasonography improves the accuracy of laparoscopic staging in patients with potentially resectable pancreatic and periampullary carcinomas. 相似文献
15.
BACKGROUND: Laparoscopy has become a popular and widespread surgical technique. An important goal in the treatment of patients with pancreatic cancer is to avoid any unnecessary procedure. Laparoscopy has been suggested as a routine tool for staging in order to prevent unnecessary laparotomies in these patients. METHODS: In this article we present our experience regarding the value of laparoscopic staging and review the literature on this topic. RESULTS AND CONCLUSION: A direct and conclusive comparison of the controversial literature is difficult because of different study designs. Inconsistent use of high-quality CT scans significantly affects the results. However, recent studies reveal that not more than 14% of the patients benefit from diagnostic laparoscopy when a state-of-the-art CT scan has been performed previously. Therefore, we conclude that routine diagnostic laparoscopy is not justified in all patients with pancreatic cancer. Rather, selective use is appropriate, especially in patients in whom ascites is an indirect sign of peritoneal metastases, or if liver metastases cannot be surely excluded preoperatively. This approach is cost-effective and limits diagnostic laparoscopy to a subgroup of patients in whom a laparotomy can be avoided. 相似文献
16.
Combined preoperative endoscopic and laparoscopic ultrasonography for prediction of R0 resection in upper gastrointestinal tract cancer 总被引:2,自引:0,他引:2
Mortensen MB Fristrup CW Ainsworth AP Pless T Nielsen HO Hovendal C 《The British journal of surgery》2006,93(6):720-725
BACKGROUND: This study evaluated the ability of combined endoscopic and laparoscopic ultrasonography to predict R0 resection and avoid unnecessary surgery in patients with upper gastrointestinal tract cancer (UGIC). METHODS: A total of 411 consecutive patients with UGIC (182 pancreatic cancers, 134 gastric cancers and 95 oesophageal cancers) treated between January 2002 and May 2004 were analysed prospectively. The allocation of patients into resectability groups by endoscopic ultrasonography (EUS) and laparoscopic ultrasonography (LUS) was compared with the treatment actually undertaken. RESULTS: The combination of EUS and LUS correctly predicted R0 resection in 90.6 per cent, R1-R2 in 91 per cent and irresectability in 91.4 per cent of patients. Ten patients (2.4 per cent) had explorative laparotomy only. There were no complications associated with the EUS and LUS procedures. CONCLUSION: The routine use of EUS and LUS before surgery predicted R0 resection in nine of ten patients and reduced the number of unnecessary laparotomies to less than 3 per cent. 相似文献
17.
Adam D. Barlow Guiseppe Garcea David P. Berry Arumugam Rajesh Roshni Patel Matthew S. Metcalfe Ashley R. Dennison 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2013,398(7):983-988
Purpose
Accurate preoperative radiological staging of hilar cholangiocarcinoma remains difficult, and a number of patients are found to have irresectable advanced tumours or occult metastases at exploration. Staging laparoscopy can improve the detection of irresectable disease, avoiding unnecessary laparotomy. This study examines the role of staging laparoscopy in hilar cholangiocarcinoma, with a focus on yield over different time periods and identification of preoperative factors increasing the risk of irresectable disease.Methods
Retrospective case note review of all patients undergoing staging laparoscopy for radiologically resectable hilar cholangiocarcinoma, identified from the hepatobiliary multidisciplinary team database, was performed.Results
One hundred consecutive patients underwent staging laparoscopy between 1998 and 2011. Of these, 34 patients were found to be irresectable due to metastatic disease, and 11, due to extensive local disease. Fifty patients proceeded to exploratory laparotomy following staging laparoscopy, and 36 % (18/50) of whom were found to have irresectable disease: 12 patients due to advanced local disease and 6 patients due to metastases. The overall yield of laparoscopy was 45 %, and the accuracy was 71 %. There was no significant difference in age, preoperative bilirubin, neutrophil/lymphocyte ratio, Ca19-9 levels or T stage between patients with resectable disease and with irresectable disease on laparoscopy. There was also no change in the yield of laparoscopy over time, despite advances in radiological imaging.Conclusion
In this series, staging laparoscopy avoided unnecessary laparotomy in 45 % of patients with radiologically resectable hilar cholangiocarcinoma. No factor was able to predict positive yield, and therefore, all patients with potentially resectable hilar cholangiocarcinoma should undergo staging laparoscopy. 相似文献18.
Khan AZ Miles WF Singh KK 《Journal of laparoendoscopic & advanced surgical techniques. Part A》2005,15(4):374-378
BACKGROUND: The majority of patients with upper gastrointestinal (UGI) tract malignancy present at a stage where cure of disease is not possible. The aim of treatment in these patients is effective palliation. Various interventions have been described for the palliation of biliary and gastric outlet obstruction including open surgery, endoscopic and transparietal stent placement. Laparoscopic bypass appears to have the advantage of decreased postoperative pain and shorter hospital stay as well as offer effective palliation. The aim of this study was to assess the safety and efficacy of laparoscopic bypass in patients with incurable UGI tract malignancy. PATIENTS AND METHODS: Between August 2000 and April 2002 laparoscopic gastric and biliary bypass concurrently or alone was attempted in 19 consecutive patients with unresectable carcinoma of the head of the pancreas, adenocarcinoma of the stomach, cholangiocarcinoma of the distal common bile duct, or adenocarcinoma of the duodenum. The operative time, length of postoperative stay, complications, and the effectiveness of the procedure in terms of the ability to sustain oral nutrition and or the relief of obstructive jaundice were recorded and used as outcome measures. RESULTS: Laparoscopic bypass was successful in 18 out of 19 cases. The mean operative time for a single bypass was 164 minutes while the average postoperative hospital stay was 11 days. All patients were able to sustain oral nutrition during the course of their hospital stay and or had effective relief from their obstructive jaundice. Two patients died from procedure unrelated causes within 30 days of the operation. CONCLUSION: Laparoscopic bypass appears to be a safe and effective means of palliation for patients with unresectable UGI tract tumors and should replace open surgical palliation in this group of patients. 相似文献
19.
目的:探讨腹腔镜超声检查技术(LUS)和腹腔镜超声刀在腹腔镜胃肠外科手术中的应用价值。方法:对50例胃肠道肿瘤等病变采用腹腔镜超声进行前瞻性肿瘤分期诊断,结合腹腔镜超声刀开展腹腔镜胃肠手术治疗。结果:经腹腔镜和腹腔镜超声分期诊断,47例肿瘤患者均明确诊断,淋巴结穿刺活检与病理结果符合率为87.5%(7/8);其中2例转开腹手术,6例避免了剖腹探查术,39例肿瘤患者成功地完成了腹腔镜手术。本组50例患者中42例在腹腔镜下成功完成姑息性或根治性胃肠切除术。平均手术时间190min,术中出血量平均120ml(20~250ml),系膜淋巴结清除数平均6.5个(5~12个),术后肠蠕动恢复时间平均36h,平均住院8.5d,无手术后并发症。术后随访3~36个月,未发现复发与转移及腹壁穿刺孔或切口转移。结论:腹腔镜胃肠手术中常规使用腹腔镜超声检查可准确为病变定位,完善肿瘤分期诊断,提高肿瘤可切除性的判断率,避免了不必要的剖腹探查;术中常规使用超声刀提高了手术安全性,扩大了腹腔镜手术范围。腹腔镜胃肠道病变切除术安全可行,近期效果良好,远期效果有待观察。腹腔镜胃肠手术将成为胃肠良恶性疾病的常规手术。 相似文献
20.