射频技术在美容领域的运用

目的：探讨射频技术治疗老年性皮肤皱纹、炎性痤疮、萎缩性瘢痕的临床疗效。方法：采用能量为20～500J的GP699A型射频热能皮肤治疗仪治疗老年性皮肤皱纹、炎性痤疮和萎缩性瘢痕患者各20例，五次为一个疗程，每次治疗间隔为10天，治疗前后给患者拍照、记录治疗参数，评估临床疗效。结果：20例老年性皮肤皱纹患者有效率为95％，20例炎性痤疮有效率为55％，20例萎缩性瘢痕有效率为55％。结论：射频电流治疗老年性皮肤皱纹有很好疗效，对萎缩性瘢痕和炎性痤疮疗效一般。     

射频治疗42例面部皱纹疗效观察

目的:观察Accentpro深蓝射频治疗仪治疗面部皮肤皱纹和松弛的效果和安全性。方法:对42例面部皮肤松弛与皱纹要求改善的患者采用Accentpro深蓝热塑射频治疗仪进行治疗,每2周治疗1次,5次为1个疗程,分别在第1次治疗前、第5次治疗后1个月、3个月观察疗效。结果:42例患者均完成1个疗程的治疗,所有患者均未发现水疱、皮肤烫伤、色素沉着和瘢痕等不良反应,显效83%,有效17%,总有效率100%。结论:Accentpro射频治疗仪治疗面部皮肤皱纹和松弛安全、有效。     

CO2点阵激光治疗面部皮肤光老化的疗效观察

目的 探讨CO2点阵激光治疗面部皮肤光老化的临床疗效.方法 自2008年10月至2010年12月,应用CO2点阵激光技术治疗皮肤老化患者30例,治疗3次为一疗程,每次间隔3个月.治疗后观察并判定其疗效.结果 30例患者经一个疗程治疗后,13(43%)例患者皱纹得到明显改善,评为3～6分;12(40%)例患者皱纹得到改善,评为6～9分;5例(17%)患者皱纹改善不明显,评为3分以下.对所有患者随访6个月,有效率达83%.结论 CO2点阵激光能有效治疗面部皮肤光老化,且安全性高、不良反应少,可将其作为当前面部皮肤年轻化治疗的新方法.     

超声波技术治疗皮肤老化临床效果的初步观察

目的观察超声波技术治疗颜面部皮肤老化的临床疗效。方法采用超声波治疗仪的特定声波强度，对60例颜面部皮肤老化者进行治疗。颜面部皮肤老化的治疗10次为一个疗程，每隔一天治疗一次，观察临床效果。针对每例患者治疗前后的对比照片，并做好记录，进行临床疗效的评估。结果本组患者60例，其中额部皱纹：显效12例，有效36例，无效12例；鱼尾纹：显效15例，有效36例，无效9例；眉间皱纹：显效6例，有效42例，无效12例。无一例出现面部红斑及损伤等不良反应。结论使用超声波皮肤治疗仪能改善面部皮肤松弛与老化，操作简单，安全可靠，患者无痛苦，易于接受，是目前具有临床推广价值的方法。     

超声波治疗仪美容美体疗效评价

目的：观察超声波皮肤治疗仪对面部皮肤的改善和身体局部的塑形作用。方法：应用超声波皮肤治疗仪对皮肤老化患者和单纯性局部肥胖者各40例进行治疗。老化性皮损隔日治疗一次,10次为一个疗程;局部溶脂塑形隔日治疗一次,15次为一个疗程。结果：超声波皮肤治疗仪对面部老化性皮损治疗总有效率85%,局部塑形总有效率82.5%。无不良反应。结论：超声波皮肤治疗仪对皮肤的老化性皮损有明显的改善,并具有一定的溶脂塑形作用。     

超声波技术治疗皮肤老化临床效果的初步观察

目的观察超声波技术治疗颜面部皮肤老化的临床疗效。方法采用超声波治疗仪的特定声波强度,对60例颜面部皮肤老化者进行治疗。颜面部皮肤老化的治疗10次为一个疗程,每隔一天治疗一次,观察临床效果。针对每例患者治疗前后的对比照片,并做好记录,进行临床疗效的评估。结果本组患者60例,其中额部皱纹:显效12例,有效36例,无效12例;鱼尾纹:显效15例,有效36例,无效9例;眉间皱纹:显效6例,有效42例,无效12例。无一例出现面部红斑及损伤等不良反应。结论使用超声波皮肤治疗仪能改善面部皮肤松弛与老化,操作简单,安全可靠,患者无痛苦,易于接受,是目前具有临床推广价值的方法。     

面中部提升术结合睑袋整形术对眶周皮肤皱纹的疗效与美容影响

目的:探究面中部提升术与睑袋整形术对眶周皮肤皱纹患者的疗效分析与美容影响。方法:选取我院2013年1月-2014年1月收治的60例眶周皮肤皱纹患者,随机分为观察组和对照组,每组30例患者,对照组采用睑袋整形术治疗眶周皮肤皱纹患者,观察组采用面中部提升术结合睑袋整形术治疗患者,观察两组患者疗效。结果:治疗后观察组并发症的情况显著少于对照组,差异具有统计学意义,P0.05;观察组患者治疗效果显著优于对照组,差异具有统计学意义,P0.05;观察组患者预后情况显著优于对照组,差异具有统计学意义,P0.05。结论:面中部提升术与睑袋整形术结合治疗眶周皮肤皱纹患者,创伤较小,恢复较好,治疗效果的持续时间较长,可有效改善下睑松弛的状况。     

点阵双极射频面部皮肤年轻化治疗临床疗效及安全性观察

目的：观察点阵双极射频在面部皮肤年轻化治疗中的临床疗效和安全性。方法：对47例存在面部皮肤老化征并要求改善的患者,采用点阵双极射频治疗仪进行3次治疗,间隔时间为4周。治疗过程中记录VAS评分及不良反应,并对比治疗前、疗程结束后1个月皮肤松弛、皱纹、肤色及光滑度的改变,并行患者满意度调查。结果：47例患者均完成3次治疗,与治疗前相比,面部皮肤松弛、皱纹、肤色及光滑度改善50％以上者分别占61．70％、72．34％、51．06％及70．21％。共91．49％的患者对治疗满意或非常满意。VAS评分平均3．12分,不良反应限于轻微水肿、红斑、微小结痂,所有患者均无色素沉着、瘢痕等。结论：点阵双极射频用于面部皮肤年轻化治疗安全、有效。     

射频技术在面部年轻化应用中的疗效

为观察OGP射频皮肤治疗仪（medical 03）治疗面部皮肤皱纹和松弛的有效性和安全性，本研 究选取2022年5月-12月中国科学院大学西安存济医学中心收治的33例面部年轻化要求改善的求美者，采 用射频皮肤治疗仪（medical 03）进行治疗，3次/周，连续8周，并随访评估治疗前、第4周、第8周的疗 效及满意度。评价包括临床医生盲态评分、患者满意度调查及Primos等。结果显示31例参与者完成了研 究；其中2例因个人原因退出。使用家用射频皮肤治疗仪（medical 03）56 d，Fitzpatrick皱纹分级平均值 下降（P＜0.05）；鱼尾纹、法令纹及前额纹面积等均有改善（P＜0.05）；治疗后总满意度为93.55%；31例 受试者未出现任何皮肤不良反应。由此可得OGP射频皮肤治疗仪（medical 03）用于面部年轻化是一种安 全、有效的手段，且无修复期、操作简单、方便。     

单极射频在面部皮肤年轻化中的初步应用

目的 探讨单极射频在面部皮肤皱纹和松弛治疗中的应用.方法 自2006年9月至2008年10月,对35例年龄为35～64岁的面部皮肤老化患者使用英国REVYOUTH公司生产的ThermaStar单极射频治疗仪行面部皮肤的细小皱纹、轻中度松弛的治疗,输出能量为75～145 J/脉冲.一个疗程为4、5次,每次间隔约3周,并于治疗前后进行测量及拍照.结果 治疗后随访所有患者3～8个月,眼周及鼻唇沟的皱纹得到明显改善,面颈部的松弛皮肤得到有效提紧.并发症较少,患者较为满意.结论 单极射频的治疗方法能有效地改善面部皮肤的皱纹及松弛,是一种安全有效、不良反应少的非剥脱性面部年轻化的治疗方法,值得临床上推广应用.     

A型肉毒毒素改善面部动力性皱纹的近期效果观察

目的探讨应用A型肉毒毒素治疗面部动力性皱纹的特点及效果评价。方法 2012年11月至2013年6月,78例面部皱纹患者,均为女性,年龄27~46岁,应用A型肉毒毒素进行面部除皱,包括额纹48例,鱼尾纹30例。注射前及注射后1、3、6、9个月分别照相,比较面部皱纹变化情况,结合患者自我感觉等指标,综合分析A型肉毒毒素注射除皱的近期效果。结果所有78例患者术后随访9个月,医患双方就术后效果共同进行评价,注射部位皱纹消除明显,患者对治疗效果满意。结论应用A型肉毒毒素治疗面部动力性皱纹,疗效良好,安全方便,副作用少,术后满意度高。     

Repeated Botulinum Toxin A Injections for the Treatment of Lines in the Upper Face: A Retrospective Study of 4,103 Treatments in 945 Patients

BACKGROUND Although botulinum toxin type A (BoNT-A) is a common aesthetic intervention, there are few published data on treatment over more than two cycles.
OBJECTIVE To evaluate the effectiveness/safety of repeated doses of BoNT-A (Dysport, Ipsen Ltd., Slough, UK) in the upper face for reduction of wrinkles.
METHODS Retrospective, cross-sectional patient chart review from 945 patients who had received a minimum of three consecutive, documented treatment cycles.
RESULTS The glabella was treated most frequently (93.9%), with the majority (81.5%) of patients receiving treatment in more than one area of the face. BoNT-A treatments were combined with other aesthetic procedures in 57.5% of cases, mostly with fillers (37.1%). There was no evidence of tachyphylaxia: the dose applied, the interval between treatments, and satisfaction with the results remained stable over the course of treatment. Adverse events were those expected with BoNT-A treatment (most common: local bruising and ptosis) and were all mild or moderate in intensity. There was no sign of any cumulative adverse effects: indeed, the adverse-event rate decreased in later treatment cycles.
CONCLUSIONS Long-term, repeated injections of BoNT-A for corrections of wrinkles in the upper face yield a continuously high level of safety and effectiveness in actual practice.     

微针诱导、敷中药膜联合海普林软膏按摩治疗面部色素沉着斑相关影响因素分析

目的：观察采用微针诱导、敷中药膜联合海普林软膏按摩治疗各种外伤所致面部色素沉着斑的临床效果,并对相关影响因素进行综合评价。方法：选择110例面部外伤后色素沉着斑患者随机分组,观察综合治疗中分别采取稀疏与密集两种针刺方式、敷中药面膜≤30im n与1h两种敷膜时间的临床疗效,经统计后分析不同因素对疗效的影响。结果：同一因素的两组之间有效率比较,均P〈0.05,差异有显著性意义。皮肤创面愈合后越早接受治疗,效果越好,疗程也短。结论：微针诱导、敷中药膜联合海普林软膏按摩治疗外伤后色素沉着,疗效可靠,无明显副反应发生。皮肤创面愈合后开始治疗时间、针刺方式及敷中药膜时间对治疗效果有明显影响。敷中药膜时间、针刺密度及按摩力度应根据新生皮肤性状进行调节。     

麻黄碱对蛛网膜下腔阻滞低血压的预防作用

目的：观察预防性注射麻黄碱对成年或成年病人腰麻期间血压的影响。方法：60例ASAI～Ⅱ级择期手术病人根据年龄和是否预防性注射麻黄碱而分成四组,I、Ⅱ组为25～55岁成年病人,Ⅲ、组为65～75岁老年病人。腰麻前30分钟快速静脉输注乳酸林格氏液7ml/kg。腰麻完成后,Ⅱ组、Ⅳ组静注麻黄碱10mg的同时肌注30mg;I组、Ⅲ组则给予等容量的生理盐水。结果：30例示用麻黄碱者,麻醉后每例MAP下降均大于20%,其中10例（I组2例、Ⅲ组8例）血压下降超过35%而需紧急处理。Ⅲ组53%病人血压下降超过35%。结论：预防性注射麻黄碱能有效地防治腰麻所致的低血压,对老年病人效果更佳。     

New indications for botulinum toxin type A in treating facial wrinkles of the mouth and neck

Botulinum toxin type A (BTX-A) is commonly used to smooth hyperkinetic lines in the periocular and forehead areas of the upper face, but has been used less frequently for indications in the lower face and neck. This study was designed to determine whether botulinum toxin treatment of the mouth and neck areas is as clinically successful as treatment of the upper face. This was a retrospective study of patients who were treated with botulinum toxin type A (BOTOX, Allergan, Inc) to soften hyperkinetic facial wrinkles. Of 100 patients randomly selected from a single clinical practice, 91 met the inclusion criteria and were divided into two groups for analysis: the 56 patients in Group 1 did not receive treatment in the mouth and neck areas, while the 35 patients in Group 2 were treated at least once in the mouth and neck areas. Patients were surveyed for periods ranging from seven to 49 months. Most patients in each group had a single BTX-A procedure during this period. Both groups of patients had comparable improvement of wrinkles both at the evaluation immediately after the neuromuscular blockade and during followup. In comparison with patients whose treatment was confined to the upper face, patients who received global treatment with BTX-A, including BTX-A injections in the mouth and neck areas, were injected in more sites per procedure and had more procedures in combination with other therapies. Patient satisfaction with botulinum toxin treatment and outcomes was high in both groups. BTX-A is an important tool within the therapeutic spectrum for the treatment of hyperkinetic facial wrinkles, including those in the areas of the mouth and neck.     

帕瑞昔布钠不同给药时机对胸科手术病人术后镇痛效果的影响

目的 探讨帕瑞昔布钠不同给药时机对胸科手术病人术后镇痛效果的影响.方法 采用前瞻性、随机、对照、双盲的研究方法.择期肺叶切除手术病人60例,采用随机数字表法,将病人随机分为3组(n=20),A组切皮前30 min和术毕前30 min静脉注射生理盐水2 ml;B组切皮前30 min静脉注射帕瑞昔布钠40 mg,术毕前30 min静脉注射生理盐水2 ml;C组切皮前30 min静脉注射生理盐水2 ml,术毕前30 min静脉注射帕瑞昔布钠40 mg.3组术后48 h内均行吗啡PCIA,维持VAS评分≤3分.术后随访,记录吗啡用量、病人镇痛满意度评分、体温、胸腔引流量及肝、肾和凝血功能情况,记录恶心、呕吐的发生情况.结果 与A组比较,B组和C组吗啡用量减少,病人镇痛满意度评分升高,体温降低(P＜0.05或0.01),B组与C组吗啡用量,镇痛满意度评分和体温比较差异无统计学意义(P＞0.05).3组间凝血功能指标、肝肾功能指标、胸腔引流量和恶心呕吐发生率比较差异无统计学意义(P＞0.05).结论 切皮前30 min与术毕前30 min静脉注射帕瑞昔布钠40 mg辅助术后镇痛效果相似,均可有效增强胸科手术病人术后吗啡镇痛效果,减少术后发热的发生.

Abstract：

Objective To investigate the effect of different time administration of parecoxib sodium on the postoperative analgesic efficacy in patients undergoing thoracic surgery. Methods This was a prospective,randomized, double-blind, placebo-controlled study. Sixty ASA Ⅰ orⅡ patients aged 17-83 yr undergoing pulmonary lobectomy were randomly allocated to one of 3 groups (n=20 each):A, B and C groups. Group A received normal saline 2 ml at 30 min before skin incision and the end of operation. Group B received iv parecoxib sodium 40 mg at 30 min before skin incision and normal saline 2 ml at 30 min before the end of operation. Group C received normal saline 2 ml at 30 min before skin incision and iv parecoxib sodium 40 mg at 30 min before the end of operation. All the patients received patient-controlled intravenous analgesia with morphine and VAS score was maintained≤3. The patients were followed up after operation.The morphine consumption, patients' global evaluation of the postoperative analgesia (0-100, 0=worst pain, 100=no pain), nausea and vomiting, body temperature , volume o chest drainage, hepatic, renal and blood coagulation function were recorded. Results Compared with group A, the morphine consumption was significantly reduced, the patient' s satisfaction score increased and body temperature decreased in B and C groups(P＜0.05 or 0.01). There was no significant difference in the morphine consumption, patient's satisfaction score and body temperature between B and C groups(P＞0.05). No significant difference was found in the parameters of hepatic, renal and blood coagulation function, volume of chest drainage and incidence of nausea and vomiting among the three groups(P＞0.05).Conclusion When postoperative analgesia is assisted with iv parecoxib sodium 40 mg given at 30 min before skin incision or at 30 min beforethe end of operation,the efficacy is similar,and both can improve the postoperative analgesic efficacy of morphine and reduce fever after operation in patients undergoing thoracic surgery.     

高压氧对肛肠病术后创面修复的影响

为探讨高压氧对肛肠病术后创面修复的影响,将150例患者分为治疗组、对照1组和对照2组。三组患者术后均给予肛肠外科常规换药、TDP理疗。在以上治疗的基础上,治疗组给予高压氧治疗,对照1组给予珍珠生肌散外用,对照2组无其他治疗。结果显示,治疗组创面愈合时间、疼痛消失时间方面均明显优于两对照组,P〈0．05或P〈0．01;两对照组比较差异无统计学意义,P〉0．05。三组不良反应发生率比较差异无统计学意义,P〉0．05。结果表明,高压氧可明显促进肛肠病术后创面修复。     

新辅助化疗对乳腺癌患者靶控输注异丙酚意识消失时半数有效效应室靶浓度的影响

目的 探讨新辅助化疗对乳腺癌患者靶控输注异丙酚意识消失时半数有效效应室靶浓度(EC50)的影响.方法 择期拟行乳腺癌切除术患者90例,女性,ASAⅠ或Ⅱ级,年龄30～60岁,体重指数<30kg/m2,根据术前是否接受新辅助化疗及其化疗方案分为3组(n=30),未化疗组(Ⅰ组)术前不使用任何化疗药物;紫杉醇化疗组(Ⅱ组)及环磷酰胺+阿霉素+5-氟尿嘧啶联合化疗组(Ⅲ组)均进行4个疗程化疗,并于第4个疗程结束后10～15d时行乳腺癌切除术.麻醉诱导:靶控输注异丙酚,按序贯法确定异丙酚的效应室靶浓度,第1例患者异丙酚效应室靶浓度为2.07μg/ml,各相邻靶浓度之比为1.09.以睫毛反射消失及对言语指令无反应作为判断意识消失的标志.若患者意识消失,则持续靶控输注该浓度异丙酚,并静脉注射芬太尼3μg/kg及罗库溴铵0.6 mg/kg后气管插管;若患者意识未消失,则停止靶控输注,静脉注射异丙酚2mg/kg、芬太尼3μg/kg及罗库溴铵0.6 mg/kg后气管插管.计算靶控输注异丙酚意识消失时的EC50.结果 与Ⅰ组比较,Ⅱ组及Ⅲ组患者靶控输注异丙酚意识消失时的EC50.均降低(P<0.05),Ⅱ组和Ⅲ组间上述指标差异无统计学意义(P>0.05).结论 新辅助化疗可降低乳腺癌患者靶控输注异丙酚意识消失时的EC50.     

肛痛消软膏防治混合痔外剥内扎术后疼痛的临床观察

为观察肛痛消软膏防治混合痔外剥内扎术后疼痛的疗效,我们将符合纳入标准的60例患者随机分为两组,治疗组30例术后给予肛痛消软膏,对照组30例术后给予太宁乳膏,分别于手术结束时及便后换药时敷于创面上。结果显示,术后0．5h及术后第10天换药后0．5h,两组间疼痛VAS评分比较均无显著性差异（P〉0．05）;术后6h至术后第7天换药后0．5h,两组间疼痛VAS评分比较均有显著性差异（P〈0．05）;两组患者均未发现药物不良反应。结果表明,肛痛消软膏用于防治混合痔术后疼痛具有明显的疗效。     

Efficacy and safety of fractional CO<Subscript>2</Subscript> laser versus fractional Er:YAG laser in the treatment of facial skin wrinkles

Ablative fractional lasers were introduced for treating facial rhytides. Few studies have compared fractional CO₂ and Er:YAG lasers on cutaneous photodamages by a split trial. The aim of the present study was to compare these modalities in a randomized controlled double-blind split-face design with multiple sessions and larger sample size compared to previous studies done before. Forty patients with facial wrinkles were enrolled. Patients were randomly assigned to receive three monthly treatments on each side of the face, one with a fractional CO₂ and one with a fractional Er:YAG laser. The evaluations included investigating clinical outcome determined by two independent dermatologists not enrolled in the treatment along with measuring skin biomechanical property of cheeks using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT). Moreover, possible side effects and patients’ satisfaction have been recorded at baseline, 1 month after each treatment, and 3 months after the last treatment session. Clinical assessment showed both modalities significantly reduce facial wrinkles (p value?<?0.05), with no appreciable difference between two lasers. Mean CRRT values also decreased significantly after the laser treatment compared to the baseline in both laser groups. There was no serious long-standing adverse effect after both laser treatments, but the discomfort was more pronounced by the participants after CO₂ laser treatment. According to the present study, both fractional CO₂ and fractional Er:YAG lasers show considerable clinical improvement of facial skin wrinkles with no serious adverse effects, but post-treatment discomfort seems to be lower with Er:YAG laser.