难治性妇产科大出血栓塞治疗的临床应用

目的:探讨难治性妇产科大出血介入栓塞治疗的临床价值和意义。方法:47例难治性妇产科大出血患者,包括产后宫缩乏力、引产后大出血、宫颈妊娠、子宫切除术后残端出血、宫颈鳞癌等。处于失血性休克状态35例,出现弥漫性血管内凝血(DIC)9例。采用Seldinger技术行右股动脉穿刺插管双侧髂内动脉造影后,行双侧髂内动脉栓塞,栓塞剂为明胶海绵。结果:44例经一次栓塞后成功止血,手术时间30～65min,平均45 min。1例子宫切除术后大出血经三次栓塞后成功止血,1例经一次栓塞后仍有活动性出血行子宫切除术,1例经两次栓塞后仍有活动性出血行子宫切除术。结论:介入栓塞治疗妇产科大出血是一种有效、迅速、安全的止血方法。     

高原地区应用介入治疗产后出血23例临床分析

目的：探讨高原地区产后出血治疗的途径。方法：对因宫缩乏力或前置胎盘、胎盘植入等引起的产后出血,用传统方法治疗效果不佳者,用介入方法栓塞子宫动脉。结果：产后出血患者23例,用传统的方法治疗不能控制出血,用介入栓塞出血动脉的方法,止血效果确切。结论：介入栓塞子宫动脉治疗产后出血效果好、创伤小、无明显并发症,且能保留患者子宫及生育功能,值得在有条件的地区推广使用。     

急诊子宫动脉栓塞术治疗产后大出血的疗效分析

目的：研究急诊子宫动脉栓塞术治疗产后大出血的疗效及对生育功能的影响。方法：回顾性分析我院2016年6月至2022年1月收治的43例产后大出血产妇分为观察组,选取同期收治的50例正常分娩的产妇分为对照组。观察两组产妇产后出血情况比较,月经情况比较,术前及术后3个月、6个月激素水平与卵巢功能比较,生活质量比较。结果：观察组止血时间（17.38±1.22）min,止血成功率100%(43/43)。两组产妇月经情况比较、术前及术后3个月、6个月激素水平与卵巢功能比较、生活质量比较无明显差异（P>0.05）。结论：子宫动脉栓塞术对治疗产后大出血具有显著效果,且对月经情况、生育功能并无较大影响。     

急诊子宫动脉栓塞术治疗产科大出血（附12例报告）

目的：评价子宫动脉栓塞术治疗产科大出血的应用价值。方法：本组病例产后大出血4例,剖宫产后大出血5例,异位妊娠出血1例,人工鎏产术后大出血2例。对12例患者行急诊血管造影并选择性栓塞子宫动脉或同时栓塞阴部内动脉、卵巢动脉。栓塞物为明胶海绵或弹簧钢丝圈。结果：栓塞后出血完全停止10例。2～7d后经对症治疗出血逐渐停止2例,未出现严重并发症。结论：急诊子宫动脉栓塞治疗产科大出血是一种安全、迅速有效的止血措施。     

双侧子宫动脉栓塞治疗产后大出血

产后子宫大出血是产科常见的严重并发症,发生率5％～10％,是我国产妇死亡的首要原因,迅速有效地控制产后出血是治疗的关键。对药物治疗无效的难治性产后出血患者实施经导管栓塞动脉止血具有快速、准确、创伤小的优点,本研究旨在探讨子宫动脉栓塞治疗产后子宫大出血的临床价值。     

急诊动脉栓塞治疗产后子宫大出血的临床应用

目的 :探讨产后子宫大出血急诊动脉栓塞的应用价值。方法 :本组 13例产后子宫大出血患者平均出血量2 2 0 0ml ,采用Seldinger法先行腹主动脉造影 ,明确出血动脉后 ,选择或超选择性插管 ,经导管注入明胶海绵颗粒和真丝线段栓塞。结果 :13例子宫大出血患者全部栓塞成功 ,随访 3个月仍无复发。结论 :急诊动脉栓塞治疗产后子宫大出血既安全、有效 ,又无严重并发症发生 ,值得临床推广使用。     

急诊选择性动脉造影栓塞治疗产后大出血18例

目的:评估急诊选择性动脉造影栓塞治疗产后大出血的效果和安全性。方法:18例产后大出血病人,出血量1 000~3 500 ml,经保守治疗无效,使用急诊选择性动脉造影栓塞治疗。结果:动脉造影显示14例(77.8%)有造影剂渗漏,16例立即止血或逐渐止血,总有效率为88.8%。2例止血失败,行子宫切除术后止血。本组未出现严重并发症,除行子宫切除术的2例,所有病人术后月经正常。结论:急诊选择性动脉造影栓塞止血迅速、安全有效,当保守治疗无效时,是一种值得推荐的子宫切除术替代方法。     

高原地区介入栓塞治疗产后大出血的护理体会

目的：观察高原地区采用介入栓塞治疗产后大出血的临床疗效及护理体会。方法：选取2012年1月—2013年12月我院收治的59例产后大出血患者行介入栓塞治疗,并给予充分的术前准备,心理护理,加强术后护理以观察术后止血的效果评价。结果：59例产后大出血患者经介入栓塞治疗后,48例立即停止出血,11例出血明显减少,9例出现低热等并发症给予相应护理措施后症状均缓解。结论：子宫动脉介入栓塞是治疗产后大出血的较好方法,而积极合理有效的护理配合是保证手术安全,减少并发症的重要保证。     

非创伤性急性大出血的介入治疗价值探讨(附185例分析)

目的：探讨非创伤性急性大出血介入诊疗方法、疗效及临床应用价值。方法：对185例非创伤性急性大出血患者采用血管造影诊断和血管内栓塞术。结果：185例介入栓塞止血成功率94％，其中150例支气管扩张、肺结核大咯血止血率92％。35例肝癌破裂止血率100％。结论：动脉栓塞治疗在急诊医学中抢救非外伤性大出血是替代保守治疗和外科手术治疗的另一种有效治疗方法。     

妇产科大出血急诊栓塞治疗

目的;介绍髂内动脉栓塞术抢救妇产科大出血的初步经验。方法：产后２例,子宫全切术２例,过期流产１例,均采用Ｓｅｌｄｉｎｇｅｒ技术经股动脉选择性插管至双侧髂内动脉,经导管注入明胶海绵颗粒栓塞双侧髂内动脉。结果：栓塞术后所有病例立即止血,过期流产致凝血功能障碍全部恢复正常。结论：髂内动脉栓塞术抢救妇产科大出血是安全有效的。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.