自体表皮细胞移植治疗白癜风患者的护理

总结自体表皮细胞移植治疗白癜风的护理经验,主要是①移植前注意对患者进行心理疏导,做好皮肤准备、物品准备及常规检查;②移植中严格无菌操作,密切观察患者在术中的不良反应;③移植后加强卫生宣教,限制局部活动,防止局部感染,调节饮食,并及时拆除敷料。认为以上3个环节的护理工作对自体表皮细胞移植的成功非常重要。     

内服黑素再生液联合自体表皮移植治疗白癜风临床观察

目的观察黑素再生液内服联合自体表皮移植治疗稳定期白癜风的疗效。方法将256例病例随机分为研究组与对照组,研究组142例内服黑素再生液联合自体表皮移植治疗,对照组114例进行自体表皮移植治疗。结果研究组痊愈率为84.5%,总有效率为98.6%,对照组痊愈率为28.1%,总有效率为57.9%。研究组痊愈率、有效率均高于对照组,两组疗法的痊愈率、有效率比较差异均有统计学意义(P<0.05)。结论内服黑素再生液联合自体表皮移植治疗白癜风疗效显著。     

自体表皮移植治疗皮节型白癜风32例疗效观察

本文应用自体吸疱表皮移植治疗３２例皮节型白癜风患者。共移植表皮２５６张，其中２４８张获色素再生，成功率为９６．９％。作者认为：移植表皮的制备、表皮的固定和移植的部位等是影响移植成功的关键。     

自体表皮移植治疗白癜风40例疗效观察

采用自体表皮移植术治疗白癜风患者40例,共移植116个白斑区,植入直径1cm皮片592处。结果皮片成活率96.28%,有效色素细胞再生率94.25%,临床总有效率97.5%。白癜风自体表皮移植疗效可靠,适合治疗局限型与节段型白癜风。     

自体表皮移植治疗白癜风55例的体会

我科于1996年5月～1998年2月对55例白癜风患者采用自体表皮移植的方法进行治疗,取得满意的效果,现报告如下。 1 临床资料 1.1 一般资料:本组患者中,男34例,女21例,年龄15～61岁,平均年龄27岁;病期3个月～10年;其中局限型33例,节段型20例,泛发型2例;皮损位于颜面部34例,颈12例,四肢9例,手背     

负压吸疱表皮移植治疗白癜风疗效观察

自 1998年底以来 ,我们利用医院中心负压吸引和自制的塑料吸杯组成吸疱装置 ,进行表皮分离自体移植治疗白癜风 13例 ,并设两组不同压力 ,现将结果报告如下。1　病例和方法1.1　治疗对象本组 13例 ,男 6例 ,女 7例 ;年龄 10～ 2 6岁 ,平均 2 0 .5岁 ;病程 10月～ 12年 ,平均 5 .     

自体表皮移植加（bFGF）治疗非平整部位白癜风疗效观察

国内自80年代末至90年代初陆续采用自体表皮移植治疗白癜风取得肯定疗效。但对发生在非平整部位的白癜风，由于皮肤活动度大，使移植表皮不易固定，皮片难以成活，手术成功率较低。本科自2005年1月至2006年10月采用自体表皮移植加碱性成纤维细胞生长因子（bFGF）治疗33例白癜风取得满意疗效，现报道如下。     

中药加自体表皮移植术治疗白癜风疗效观察

目的 探讨白癜风治疗的有效方法。方法 对３８例患使用中药白癜风冲剂配合自体表皮移植治疗。结果 取得了９７．１８％的总有效率（成活率）,明显高于单纯自体表皮移植对照组（Ｐ〈０．０１）,且色素在１月内恢复明显高于对照组（Ｐ〈０．０１）。部分患进行１￣２年的随访,少数皮片的色素有消退趋势,但治疗组要好于对照组。结论 该法是目前治疗白癜风较为理想的一种局部外治方法。     

Children's ibuprofen suspension for the acute treatment of pediatric migraine

OBJECTIVE: To compare the efficacy of a single over-the-counter dose (7.5 mg/kg, p.o.) of children's ibuprofen suspension vs. placebo for the acute treatment of pediatric migraine. BACKGROUND: Migraine occurs in 4% of young children. There is a paucity of controlled clinical research in the treatment of childhood migraine and there are currently no approved drugs in the USA for treatment of migraine in children < or = 12 years of age. The purpose of this study is to assess the efficacy and tolerability of a single OTC dose of ibuprofen suspension for the acute treatment of childhood migraine. METHODS: Prospective, double-blind, placebo-controlled, parallel group, randomized study of children 6-12 yrs with migraine (I.H.S.-R 1997) treating 1 attack with a 7.5 mg/kg liq. ibuprofen vs matching placebo. Efficacy measures: (1). Headache severity based upon a 4 pt scale (severe, mod., mild, no headache) at 30, 60, 90, 120, 180 and 240 minutes post dose, and (2). nausea, vomiting, and photo/phonophobia at 120 min. The 1 degrees endpoint was cumulative % of responders (severe or mod. headache reduced to mild or none) by 120 minutes. Secondary endpoints were headache recurrence within 4-24 hours and need for rescue medicines within 4 hours. RESULTS: 138 enrolled; 84 treated/completed diary. 45 active agent, 39 placebo. The 2 groups were comparable (active: placebo) - Ages: 9: 9.1, gender boy/girl - 1.25: 1.6, and diagnosis: migraine w/o aura - 86%: 79%. Concomitant use of prophylactic Rx: 24%: 10% (Table 3). Nausea was eliminated in 60% of the ibuprofen treated patients and 39% of the placebo group (p<0.001). Vomiting, photophobia and phonophobia had marginal, but not statistically significant, decreases at 2 hours. A striking gender difference was noted (Table 4): No AE's were reported. CONCLUSION: Children's ibuprofen suspension at an OTC dose of 7.5 mg/kg is an effective and well-tolerated agent for pain relief in the acute treatment of childhood migraine, particularly in boys. There is a striking difference in gender response rates and placebo responder rates between girls and boys. The boys responded at a statistically significant rate, and girls failed to do so because of a very high placebo responder rate. Multi-center trials are recommended.     

改良支气管肺泡灌洗液细胞分类计数制片及染色法

目的改良支气管肺泡灌洗液细胞分类制片及染色方法,并对其临床实用性进行验证。方法随机抽取50例门诊及住院患者肺泡灌洗液标本,分别用改良的自动化瑞氏吉姆萨染色法及传统手工HE染色法染色,由两名具有专业技术能力的检验人员分别进行显微镜下细胞分类计数,评估两种制片方法检测结果的可比性。结果两种方法对肺泡灌洗液中吞噬细胞、中性粒细胞、淋巴细胞和嗜酸性粒细胞计数一致性较好,相关系数(r)均0.95。改良法染色的细胞形态完整,细胞核和细胞浆分辨清楚,可见颗粒、空泡等细微结构;而传统法染色后的细胞固缩明显,细胞体积变小,细胞核和细胞浆分辨清晰度下降,颗粒和空泡等细胞结构辨认不清。改良法比传统法省去了滤液离心富集细胞的过程(6 min),并且使用自动化瑞氏吉姆萨染色法(20 min)代替了手工HE染色法(30 min),每份标本至少节省了15~20 min的制片和染色时间。结论改良的自动化瑞氏吉姆萨染色法优于手工HE染色法,更适用于支气管肺泡灌洗液细胞分类计数,尤其是批量检测。     

注射用利培酮微球治疗精神分裂症对照研究

目的：探讨注射用利培酮微球治疗精神分裂症的疗效和安全性。方法将160例精神分裂症患者采用随机数字表法分为两组,每组80例,观察组予以肌内注射利培酮微球治疗,对照组口服利培酮片治疗,观察6个月。治疗前后采用阳性与阴性症状量表评定临床疗效,随时记录治疗过程中出现的不良反应。结果治疗6个月后两组阳性与阴性症状量表各因子及总分评分均较治疗前显著下降（P＜0．01）,观察组评分显著低于对照组（P＜0．01）。观察组不良反应发生率为41．3％,对照组为63．8％,观察组显著低于对照组（ P＜0．01）。结论注射用利培酮微球治疗精神分裂患者疗效显著,安全性高,优于口服利培酮片剂治疗,值得临床推广应用。     

Anger control: A case study of a stress inoculation treatment for a chronic aggressive patient

A 27-year-old female, hospitalized primarily for anger and aggressive behavior, was treated using a stress inoculation model. Unobtrusive and self-report measures were obtained for a 3-month baseline period, 1-month treatment period, and 12-month follow-up period. Results showed that there was a long-term and stable reduction in perceived anger by the client, and in actual aggressive acts. In addition, there was a long-term and stable increase in the client's prosocial behaviors. The results demonstrated that this model is an effective treatment modality for hospitalized patients with severe anger and aggressive behavioral problems.