腹部超声和超声内镜在胃间叶组织肿瘤中的诊断价值

目的 探讨腹部超声和超声内镜在胃的间叶组织肿瘤中的诊断价值。方法 通过对４６例胃平滑肌肿瘤和２１例胃恶性淋巴瘤进行超声诊断,分析了平滑肌瘤、平滑肌肉瘤及恶性淋巴瘤的临床症状和声像图特点,并与手术随访结果作了对照。结果 超声诊断胃平滑肌瘤３６例,符合率９１．７％（３３例／３６例）;平滑肌内瘤符合率９０％（９例／１０例）,恶性淋巴瘤符合率７１．４（１５例／２１例）。结论 腹部超声和超声内镜在胃的间叶组     

经内镜微超声探头诊断胃粘膜下肿瘤的价值

经内镜微超声探头诊断胃粘膜下肿瘤的价值［金震东等．中华超声影像学杂志，１９９７，６（６）：２８９］探讨经内镜微超声探头（ＴＥＭＰ）诊断胃粘膜下肿瘤的价值，与胃镜和超声内镜作了比较研究。结果：（１）１８例胃粘膜下肿瘤以粘膜下平滑肌瘤居多，占８８．９％，...     

超声内镜对食管平滑肌瘤诊断价值

目的探讨超声内镜对食管平肌瘤的诊断价值.方法通过对52例食道粘膜下隆起进行超声内镜检查,并与手术病理进行比较.结果 44例食管平滑肌瘤声像图特征为粘膜肌层或固有肌层低回声结构;44例病检提示平滑肌瘤43例,超声内镜检查准确率为97.7%.结论超声内镜在食道平滑肌瘤的诊断和鉴别诊断中有重要的价值.     

上消化道平滑肌肿瘤临床及病理特点

目的 探讨上消化道平滑肌肿瘤的临床及病理特点。方法 回顾性分析92例上消化道平滑肌肿瘤临床、病理及内镜检查资料。结果 上消化道平滑肌肿瘤的主要临床表现为吞咽不适、腹痛、体重减轻及上消化道出血等，本组病例以食管和胃底平滑肌瘤多见，平滑肌瘤73例，平滑肌肉瘤19例。内镜的确诊率为91％，内镜下多表现为隆起结节状，26％病例肿瘤的表面有溃疡形成，以平滑肌肉瘤多见。平均32个月的随访中，16例平滑肌肉瘤患者死于转移，3例平滑肌肉瘤患者有局部复发。结论 上消化道平滑肌瘤以食管和胃底平滑肌瘤多见，以良性肿瘤居多，内镜为诊断的有效手段，但确诊仍靠病理检查。手术和内镜电凝切除是治疗的有效方法。     

小探头超声内镜在食管平滑肌瘤诊治中的应用

目的：探讨小探头超声内镜（MPS）在食管平滑肌瘤诊治中的应用。方法：对132例食管黏膜下隆起者先行小探头超声内镜检查,76例超声诊断为食管平滑肌瘤,对其中56例局限于黏膜肌层的食管平滑肌瘤行高频电圈套切除术（EMR）,术后标本送病理检查。结果：56例患者均成功圈套切除病变,病理均提示为起源于黏膜肌层的平滑肌瘤,与超声诊断结果一致。结论：小探头超声内镜可清晰显示食管平滑肌瘤的病变层次结构,在其引导下圈套切除食管平滑肌瘤是一种安全、有效、创伤小的治疗方法。     

腔外型小肠平滑肌瘤的超声研究

目的：评价超声检查对腔外型小肠平滑肌瘤的临床意义。方法：采用Ａｌｏｋａ ＳＳＤ６３０和５００ 型超声显像仪检查了１２ 例腔外型小肠平滑肌瘤。结果：腔外型小肠平滑肌瘤在声像图上具有一定的特征性征象：（１）肿瘤大多数位于脐部;（２）体积较大,外形呈椭圆形或不规则形;（３）边缘清晰,但无包膜回声;（４）内部回声呈蜂窝状;（５）后方回声无衰减或增强效应;（６）用探头加压时,肿瘤无压缩性。此外,本文还提出了腔外型小肠平滑肌瘤与其他疾病相鉴别的依据。结论：超声检查对腔外型小肠平滑肌瘤的诊断具有重要的临床意义,因此是首选检查方法。     

胃平滑肌肿瘤9例报告

胃平滑肌肿瘤９例报告成都铁路局中心医院（６１００８１）李豫川成都电子科技大学医院刘光霞胃平滑肌瘤和平滑肌肉瘤是起源于平滑肌组织的肿瘤，前者为良性，后者为恶性。两者临床均无特异症状，内镜表现基本相同。现报告我院１９８６～１９９３年经手术病理证实的９例，...     

57例子宫非典型性平滑肌瘤与平滑肌肉瘤的临床病理鉴别 …

为研究子宫非典型性平滑肌瘤与平滑肌肉瘤二者间的鉴别诊断，我们对随诊资料完整的５７例子宫非典型性平滑肌瘤与平滑肌肉瘤进行形态学特征的研究和分类结果表明：诊断子宫平滑肌肉瘤平滑肌肿瘤应以临床表现，大体，光镜观察和其它辅助诊断手段相结合，多方面加以考虑，才能做出正确的或较正确的病理诊断。     

子宫平滑肌肿瘤临床病理分析

目的总结子宫平滑肌肿瘤临床病理组织学分型。方法回顾性分析300例子宫平滑肌肿瘤的临床病理资料。结果子宫肌壁间258例（86%）,浆膜下18例（6%）,黏膜下24例（8%）,平滑肌瘤276例（92%）,平滑肌肉瘤2例（0.67%）,交界性平滑肌瘤22例（7.33%）。结论良性平滑肌瘤最多见,恶性平滑肌瘤很少见,交界性平滑肌瘤将会随着诊断水平的不断提高越来越少。     

子宫交界性平滑肌瘤的临床特征及治疗

子宫交界性平滑肌瘤的临床特征及治疗闻立红郑州铁路中心医院妇产科郑州４５００５２关键词子宫肌瘤；平滑肌瘤；临床特征近年来，国内外部分学者［１，２］发现子宫良性平滑肌瘤与平滑肌肉瘤之间存在着一组交界性肿瘤，包括富于细胞型平滑肌瘤、奇异性平滑肌瘤、核分裂活...     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.