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1.
目的 探讨1988-1998年间双胎妊娠发生率、并发症以及新生儿死亡率。方法 将双胎发生率、并发症以及围产儿死亡率作临床分析。结果 双胎妊娠115例中早产42例占36.52%,剖宫产57例,占49.56%,围产儿死亡率5.22%,是同期单胎死亡率1.44%的3.6倍。并发症以妊高征为多,34例占29.56%。结论 双胎妊娠应加强产前检查、增加营养、避免胎膜早破,早产、降低围产儿死亡率。 相似文献
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目的 :探讨双胎妊娠合并贫血对妊娠结局的影响。方法:将 4 7例双胎妊娠分为两组 ,贫血组 2 1例 ,对照组 2 6例 ,对两组病例妊高征、胎膜早破、早产发生率与孕妇平均年龄、新生儿平均出生体重、新生儿 Apgar评分分别进行比较分析。结果 :贫血组妊高征、胎膜早破、早产发生率显著高于对照组 (P <0 .0 1) ,贫血组新生儿 Ap-gar评分 1min及 5 m in评分均显著低于对照组 (P <0 .0 5 ) ;贫血的严重程度与新生儿平均出生体重、新生儿 Ap-gar评分 1m in及 5 m in评分呈负相关 (P <0 .0 1)。结论 :双胎妊娠合并贫血时 ,易发生妊高征、胎膜早破、早产及低体重儿 ,对孕期及围产儿具有不良影响 ,贫血程度加重时 ,对围产儿的危害增加。 相似文献
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为探讨双胎妊娠孕产期并发症的预防和处理,分析2002年1月-2005年12月50例双胎妊娠孕产妇临床资料。结果,双胎妊娠发生贫血6例(占12%)、妊高征24例(占48%)、早产19例(占38%)、胎膜早破14例(占28%)、产后出血12例(占24%),围产儿死亡率180‰。应加强双胎妊娠的产前监护,提前住院分娩,以期发现异常及时处理。 相似文献
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自1988年1月~1993年12月我院共分娩10124例,双胎82例。结果表明:双胎组早产,妊高征、贫血、胎膜早破、产后出血和围产儿死亡率明显高于单胎组,为此提出:①有双胎家族史、由药物诱导排卵的孕妇、孕吐严重、先兆流产和子宫大于停经月份者应作B超检查,有助于双胎的早期诊断。②妊娠32周以后,双胎孕妇应连续卧床休息,注意营养,治疗合并症,对减少早产、增加新生儿体重和降低围产儿死亡率有重要意义。 相似文献
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杨秀群 《广西医科大学学报》1997,14(4):96-97
分析105例重度妊高征的110例围产儿(其中5例为双胎)的情况,并与同期100例中度妊高征的100例围产儿和随机抽取同期100例正常单胎之围产儿情况进行比较。结果重度妊高征的新生儿窒息率、Apgar≤7分者及早产发生率、围产儿死亡发生率分别为20.8%、26.3%、15.4%,均明显高于中度妊高征组的13%、13%、2%和对照组的4%、1%、0(P<0.05)。重度妊高征和中度妊高征的比较(0.05>P>0.01),重度妊高征与对照组的比较(P<0.01)有极显著意义,表明重度妊高征围产儿的患病率和病死率高。 相似文献
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自1988年1月~1993年12月我院共娩10124例,双胎82例,结果表明,双胎组早产,妊高征,贫血,胎膜早破,产后出血和围产儿死亡率明显高于单胎组,为此提出:①有双胎家族史,由药物诱导排卵的孕妇,孕吐严重,先兆流产和子宫大于停经月份者应作B超检查,有助于双胎的早期诊断,②妊娠32周以后,双胎孕妇应连续卧床休息,注意营养,治疗合并症,对减少早产,增加新生儿体重和降低围产儿死亡率有重要意义。 相似文献
7.
重度妊娠高血压综合征对围产儿的影响及孕期监护 总被引:5,自引:0,他引:5
215例妊娠高血压综合征按重度、轻中度进行分析,并选择同期正常单胎40例作为对照,结果表明重度妊高征的早产发生率、低体重儿、胎儿宫内窘迫及新生儿窒息、围产儿死亡率均较轻中度妊高征及对照组明显增加,说明重度妊高妊对围产儿危害极大。通过加强孕期预防和监测,并积极治疗,适时终止妊娠,可减少围产儿发病率及死亡率。 相似文献
8.
51例双胎妊娠并发症的护理 总被引:1,自引:0,他引:1
双胎妊娠由于妊娠期间母儿合并症多,早孕反应重,多数孕妇出现贫血,妊高征,胎膜早破等症状,分娩时难产率高,围产儿死亡率明显高于单胎妊娠。近5年来我院对围产保健工作加强,针对双胎妊娠以及合并症于产前、产时、产后进行特殊护理,降低了围产儿的死亡率,以及母亲的危险性。 相似文献
9.
围产儿死亡39例临床分析 总被引:1,自引:0,他引:1
目的:分析孕母合并症、并发症与围产儿死亡的关系。方法:对我院1997年一年间39 例(其中死胎28例,死产2例,新生儿死亡9例)。围产儿死亡与母亲所患疾病的关系进行分析。结果:1997 年死亡围产儿母亲并发症、合并症中早产、畸形、胎盘早剥、妊高征、妊娠胆汁淤积症居前5位。围产儿死亡率为26.07‰,其中死胎、死产、新生儿死亡分别为71.79% 、5.12% 、23.08% 。低体重儿占死亡围产儿的半数以上。结论:加强产前检查,降低死胎的发生率,是降低围产儿死亡率的关键。 相似文献
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Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD. 相似文献
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Jiageng Zhu Jun Li Ruipeng Ji Jianghao Su Mingshun Shen Zhigang Cao 《南京医科大学学报(自然科学版)》2007,21(2):125-128
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment. 相似文献
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Tao Ye * Zhi-quan Liu Jian-jun Mu Xi-han Fu Jun Yang Bao-lin Gao and Xiao-hong Zhang Department of Cardiology First Hospital of Xi'an Jiaotong University Xi'an Hanzhong Cardiovascular Institute Hanzhong 《中国医学科学杂志(英文版)》2004,19(4):248-251
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure. 相似文献
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目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险. 相似文献
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Jingming Zhu Ningning Hui Xiuhong Jiang Huaxing Zhang Chengzhang Fu 《南京医科大学学报(自然科学版)》2007,21(6):386-389
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients. 相似文献
16.
Objective:To investigate the gene expression of osteoprotegerin(OPG) and osteoclast differentiation factor(ODF) in the bone tissue of patients with hip fracture due to osteoporosis. Methods:OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers(over 50 years old) with hip fracture(Observer Group) and 30 cases of hip facture sufferers with no osteoporosis(Control group) were analyzed with the Semi-Quantitative RT-PCR method. Results:The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion:Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption. 相似文献
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Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P. 相似文献
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Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine. 相似文献
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Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center. 相似文献
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Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine
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A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes. 相似文献