Successful repeat transcatheter ablation of a mediastinal parathyroid adenoma 6 years after alcohol embolization

Recurrent hyperparathyroidism is rare following transcatheter ablation of mediastinal parathyroid adenomas. When it occurs it is usually early and resistant to further attempts at ablation. We present a patient with primary hyperparathyroidism in whom two surgical attempts at cure had been unsuccessful. Subsequently, a mediastinal adenoma was demonstrated angiographically and embolized with absolute alcohol. Hyperparathyroidism recurred 6 years later and the mediastinal adenoma was subsequently successfully ablated a second time by angiographic embolization with ionic contrast medium.     

Giant anterior mediastinal parathyroid adenoma

ABSTRACT: A 57-year-old woman with type 2 diabetes was admitted to our hospital presenting with generalized bone pains, hypercalcemia, and elevated parathyroid hormone level. Enhanced CT scan demonstrated a large soft tissue mass in the right anterior mediastinum. Tc-MIBI scintigraphy revealed the focal accumulation of radiotracer uptake in the anterior mediastinum. Tc-MIBI SPECT/CT imaging also corroborated the same finding. The patient underwent surgery to have a giant ectopic parathyroid adenoma (7 × 4.5 × 1.5 cm) removed. The patient has been observed for 2 years, with normal parathyroid hormone and calcium levels.     

Ultrasound guided laser ablation of a parathyroid adenoma.

We present a case of primary hyperparathyroidism with severe hypercalcaemia, treated successfully with ultrasound (US) guided percutaneous interstitial laser photocoagulation (ILP) of a single parathyroid tumour. To our knowledge, this is the first reported case of ILP applied in primary hyperparathyroidism. US guided thermic tissue coagulation with ILP may be a non-surgical alternative in patients with symptomatic hypercalcaemia due to a parathyroid tumour when surgery is contraindicated.     

CT引导下经皮穿刺注射乙醇治疗甲状旁腺腺瘤

目的 探讨CT引导下经皮穿刺乙醇注射(PEI)治疗甲状旁腺腺瘤所致甲状旁腺功能亢进的疗效。方法 1例经活检证实的甲状旁腺腺瘤，在CT引导下用22G细针从前外方穿入病灶，在病灶多点、分次注射无水乙醇。结果 经过2次CT引导下PEI治疗，6个月后复查CT，示病灶体积显著缩小、由显著强化转变为无强化，治疗结束后2d至12个月，血甲状旁腺素、血钙、血磷均恢复至正常水平，临床症状显著改善。结论 CT引导下PEI治疗甲状旁腺功能亢进症疗效佳、创伤小，可作为手术治疗的重要补充。     

Resection of a mediastinal parathyroid adenoma by video-assisted thoracoscopy radio-guided by a gamma probe. A case report

We present a case of primary hyperparathyroidism in a 47 year old woman. The pre-operative 99mTc-sestaMIBI scan detected a single parathyroid adenoma located in the anterior or medium mediastinum. Surgery was carried out following 99mTc-sestaMIBI administration and using gamma probe radio-guided video-assisted thoracoscopy. The aim of this case report is to present this technique that allows adenoma resection with minimally invasive surgery. A reduction of surgical complications and an increase in the probability of surgical success could be obtained.     

Giant parathyroid adenoma demonstrated by dual tracer parathyroid imaging

Noninvasive diagnostic imaging modalities have played an increasingly important role in preoperative localization of parathyroid lesions. The radionuclide method using TI-201 and Tc-99m subtraction imaging is quite successful in detecting such lesions, with a reported sensitivity of 92%. A case of surgically proven primary hyperparathyroidism, caused by an unusually large parathyroid adenoma and detected by the dual tracer method, is presented.     

Gray-scale echographic visualization of a parathyroid adenoma

A large parathyroid adenoma and a smaller follicular thyroid adenoma were visualized with a combination of radionuclide imaging and gray-scale ultrasound in a patient with primary hyperparathyroidism.     

Intrathyroidal parathyroid adenoma: preoperative identification and localization by parathyroid imaging

The authors report, probably for the first time, a successful pre-operative localization of 7 mm intrathyroidal parathyroid adenoma which was successfully removed by using parathyroid imaging using a dual tracer (T1-201 and Tc-99m) and subtraction technique.     

Dysphagia revealing a giant cystic parathyroid adenoma

The aim of this observation was to report a rare case of symptomatic and non-functional cystic parathyroid adenoma in a 52-year-old female, diagnosed with imaging and treated by surgical resection of the gland.     

异位甲状旁腺瘤一例

甲状旁腺瘤少见,异位甲状旁腺瘤更为少见,文献大多为核素显像的个案报告,CT表现与诊断的报告极少.笔者报告1例CT诊断并经病理证实的异位甲状旁腺瘤.