Effect of Foveal Pit Restoration in Foveal Avascular Zone after Surgery for Idiopathic Epiretinal Membrane

PurposeTo investigate the relationship between ophthalmic parameters—including optical coherence tomography (OCT) and OCT angiography findings—and foveal pit restoration in eyes that had undergone vitrectomy for idiopathic epiretinal membrane (iERM) removal.MethodsThis study retrospectively analyzed data of patients who underwent pars planar vitrectomy for the removal of epirentinal membrane. Only eyes with iERM above stage 2 with a follow-up over 6 months were included. Baseline data and changes in ophthalmic parameters were analyzed from 3 months before to 12 months after surgery. Additionally, we stratified iERM patients into two groups (foveal pit restoration and no restoration group). Longitudinal comparison analyses between the two groups were done in best-corrected visual acuity (BCVA), central foveal thickness (CFT) and foveal avascular zone (FAZ) areas measurements using swept-source OCT and OCT angiography.ResultsForty-three patients with a mean age of 75 ± 5 years were enrolled. After surgery, BCVA, FAZ, and CFT showed improvements over time (all p < 0.002). Thirty-one patients were designated into the foveal pit restoration (R) group and 12 patients into the no restoration (NR) group. Differences in BCVA and FAZ area in both groups existed up to 6 months. However, BCVA improved and FAZ expanded (R, 0.20 ± 0.05 vs. NR, 0.18 ± 0.04) in both groups showing no statistical difference 12 months postsurgery. The CFT decreased in both groups, but the R group was thinner at every point compared to the NR group (all p < 0.05).ConclusionsThe removal of epirentinal membrane in pars planar vitrectomy significantly improves BCVA, decreases the CFT and expands the FAZ. Foveal pit restoration improves BCVA, CFT, and FAZ area possibly at a faster rate in the early months but long-term improvements could be achieved regardless of the status of foveal pit restoration.     

黄斑视网膜前膜的临床分析

目的 探讨特发性及继发性黄斑视网膜前膜的临床特点、光学相干断层(OCT)检查及手术效果.方法 对2005年11月至2009年4月于眼科进行玻璃体切割术、黄斑前膜剥除术的36例患者38只眼,其中特发性黄斑前膜25只眼,继发性13只眼,分别对其眼部情况、OCT检查、手术方法、术后疗效进行分析.结果 OCT显示36例38只眼术后1个月及术后3个月黄斑区中心凹厚度均比术前明显减少;36例38只眼术后随访矫正最佳视力提高2行者27只眼,占71.1%;特发性黄斑前膜25只眼比继发性黄斑前膜13只眼术后随访视力提高明显.结论 光学相干断层(OCT)检查对于黄斑前膜诊断、术后观察具有十分重要的价值;玻璃体切割手术剥除黄斑前膜对达到手术指征的黄斑前膜患者是一种有效治疗手段.     

Evolution of lamellar macular hole studied by optical coherence tomography

Purpose  To study the natural course of lamellar macular hole (LMH) as examined by optical coherence tomography (OCT) in a noncomparative observational case series. Methods  Forty-one eyes of 41 patients with LMH were included in this analysis. Baseline and final OCT findings related to LMH diameter, foveal thickness and visual acuity (VA) were collected and compared. Mean follow-up was 37.1 months. Main outcome measures were best-corrected visual acuity (BCVA), diameter of the LMH opening, foveal thickness, epiretinal membrane (ERM), posterior vitreous detachment (PVD) and vitreoretinal traction. Results  The diameter of the LMH increased by an average of 13.7%. A statistically significant association was found between the LMH diameter increase and the presence of ERM. The mean foveal thickness depicted a statistically significant decrease between the initial and the final examination. The decrease of the foveal thickness showed to correlate with visual acuity deterioration. BCVA was stable in 30 (78%) and deteriorated in 11 (22%) cases. In eight of the 11 cases, the visual acuity deterioration ranged from 2 to 15 letters. Conclusion  We identified an increase of LMH diameter related to the presence of ERM and a decrease of the foveal thickness within a period of observation which ranged from 24 to 54 months (mean 37.1 months). The study is not related with any proprietary or commercial interests. No sponsoring organizations have been involved and no grants were received from any organization or institution.     

特发性黄斑前膜术后黄斑解剖结构和功能恢复研究

目的 研究特发性黄斑前膜(Idiopathic macular epiretinal membrane,IMEM)经玻璃体切割联合黄斑前膜剥除手术后,黄斑解剖结构及视功能恢复情况,探讨影响IMEM术后视力恢复的因素.方法 临床病例系列研究.对2012年2月至2013年7月在安阳眼科医院入院行手术治疗的IMEM患者52例(54只眼),收集患者术前的最佳矫正视力(best corrected visual acuity,BCVA)、黄斑中心凹厚度(central foveal thickness,CFT),视物变形情况,术后随访4～8个月,平均(6.5±1.1)个月,所得数据进行配对资料t检验和pearson相关性分析.结果 IMEM患者术前术后BCVA对比差异有统计学意义,P ＜0.05(t=2.17;P=0.04),术前、术后CFT比较差异有统计学意义,P＜0.05(t=9.75;P =0.00),术前CFT与术前视力及术后视力经Pearson相关性分析差异无统计学意义(r=0.03,0.17;P =0.81,0.23),术后CFT与术后视力经相关性分析差异有统计学意义(r=0.27;P=0.05),术前BC-VA与术后BCVA经相关性分析差异有统计学意义(r=0.78;P=0.00),术前CFT与术后CFT经相关性分析差异有统计学意义(r=0.47;P=0.00).结论 经玻璃体切割联合黄斑前膜剥除手术后,IMEM患者CFT较术前降低,视力有所提高,但是术前CFT似对患者最终的视力恢复无明显关系,患者术后恢复更多取决于术前的视力,而不是黄斑中心凹的厚度.     

Assessment of Risk Factors Affecting Refractive Outcomes after Phacovitrectomy for Epiretinal Membrane

PurposeTo investigate factors associated with refractive outcomes after phacovitrectomy for epiretinal membrane (ERM).MethodsRetrospective review of patients undergoing phacovitrectomy for ERM was done. The main outcome measure was predictive refraction error (PE), defined as observed refraction error – target refraction error, calculated by the SRK/T, Haigis, and SRK II formulae. PE was measured at postoperative 1, 3, and 6 months. Simple and multiple linear regression analysis were used to evaluate factors associated with PE.ResultsA total of 53 eyes of 53 patients were included. The mean PEs at postoperative 1, 3, and 6 months were all negative, implying myopic shift in all patients regardless of the intraocular lens formula used. Haigis formula showed the least myopic shift among the three formulae (p = 0.001, Friedman test). There was no significant difference in PE depending on preoperative central macular thickness (CMT) in subgroup analysis. On stepwise multiple linear regression analysis, ERM etiology (β = 0.759, p = 0.004, SRK/T formula; β = 0.733, p = 0.008, Haigis formula; β = 0.933, p < 0.001, SRK II formula), preoperative anterior chamber depth (β = −0.662, p = 0.013, Haigis formula; β = −0.747, p = 0.003, SRK II formula), and decrease of CMT (β = −0.003, p = 0.025, SRK/T formula) were significantly associated with PE at postoperative 6 months.ConclusionsMyopic shift in PE was observed after combined phacovitrectomy for epiretinal membrane. ERM etiology, preoperative anterior chamber depth, and decrease of CMT were significantly associated with PE at postoperative 6 months. There was no difference in PE after surgery between the two groups defined by CMT (≥500 and <500 μm).     

Morphological and Functional Retinal Assessment in Epiretinal Membrane Surgery

Purpose: To analyze functional and morphological findings after surgery for idiopathic epiretinal macular membrane (IEMM). Materials and Methods: Twenty eyes of 20 patients affected by IEMM underwent 23-Gauge surgery. Morphological and functional examinations were assessed at baseline and at 30, 90, and 180 days after surgery. SD-OCT evaluated foveal morphology and thickness, photoreceptor inner/outer segment junction, and external limiting membrane. Functional assessment evaluated visual acuity, retinal sensitivity, and fixation patterns. Statistical analysis was performed with the Student’s t test and Pearson correlation test. Results: Mean central retinal thickness (CRT), visual acuity (VA), and retinal sensitivity (RS) at baseline were respectively 494.90 ± 38.73 µm, 0.55 ± 0.08 LogMAR, and 11.13±1.02; after surgery, at day 180, we observed a significant decrease in mean CRT to 326.90±32.68 µm, an increase in mean VA to 0.33 ± 0.05 LogMAR (p < 0.05), and in mean RS to 13.25 ± 0.73 dB (p < 0.05). A stable fixation increased from 40% of patients at baseline to 75% of patients at day 180 (p < 0.05). Discussion: IEMM surgery results in continuous improvement in visual function, not only at month one but also beyond month six, due to the progressive reduction of residual intraretinal edema and recomposition of retinal layers.     

Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes

Purpose

To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs).

Methods

Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V_postop, logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced.

Results

V_postop was determined to be significantly correlated with the preoperative visual acuity (V_preop) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V_postop was derived from the most accurate regression analysis: V_postop=0.248×V_preop+1.1×10^-6×A²-0.121×D+0.19.

Conclusions

The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer.     

应用光学相干断层扫描观察视网膜前膜的特征

目的 :用光学相干断层扫描 (OCT)描述视网膜前膜的不同特征。方法 :15 1个病人 ,170只眼 (男 77例 ,女 74例 ,平均年龄为 67 79± 10 72岁 ,范围 7至 91岁。平均视力为 0 482± 0 2 9,范围 0 0 1～ 1 2 )临床上被诊断为视网膜前膜者行OCT检查。两例年轻患者为外伤后视网膜前膜者 ,已行人工晶体手术者为 3 2例 ,糖尿病患者为 48例。每位患者双眼均在散瞳下用 4mm长扫描线行四个方向放射状线性扫描。结果 :OCT证实所有患眼黄斑中心凹曲线有不同程度的改变 ,中心凹处视网膜内界膜至色素上皮的厚度增至 2 93 92±12 5 47um ,范围为 12 4～ 72 1um。OCT表现为黄斑中心凹变平或隆起 ,内表面一强反光带为前膜 ,平均厚度为 47 18± 10 3 7μm ,范围为 3 4～ 75 μm。所有患眼均有程度不同的视网膜水肿 ,OCT表现为视网膜增厚伴有低反射腔隙。 14只眼为假性裂孔。 19例双眼受累。平均视力为 0 45 8± 0 3 2 ,范围为 0 0 1～ 1 2。结论 :OCT可帮助发现视网膜前膜对视网膜的牵拉及水肿程度 ,有助于及早采取治疗措施     

Three-dimensional characterization of epiretinal membrane using spectral domain optical coherence tomography

Purpose

To describe epiretinal membrane (ERM) features using spectral domain optical coherence tomography “SD OCT” and to delineate the three-dimensional (3D) relationship in eyes with epiretinal membrane.

Methods

Fifty-two eyes of 44 patients with ERM were classified into two groups: idiopathic ERM and secondary ERM. Posterior vitreous face was evaluated. Pattern of ERM attachment was divided into: focal and global. A 3D SD OCT system (5 μm resolution) was used for scanning. Surface maps were used to study retinal topography.

Results

Surface maps revealed manner and direction of epiretinal traction, pattern of attachment and blood vessel involvement. In 55.8% of eyes the membrane was globally adherent to the retina. There was a significant association (p = 0.02%) between pattern of membrane attachment and etiological classification of eyes. Posterior vitreous detachment (PVD) was associated with both groups, but no significant difference in between.

Conclusion

Spectral domain OCT allowed better characterization of ERM including: visualization, extension, cleavage plane and zones with free edges. Surface maps revealed the topography of ERM and retina pathology. Idiopathic ERM are significantly associated with global pattern. PVD plays an important role in the pathogenesis of primary as well as secondary ERM.     

Peripapillary RNFL Thickness Changes Evaluated with Spectral Domain Optical Coherence Tomography after Uncomplicated Macular Surgery for Epiretinal Membrane

Purpose. To evaluate the peripapillary RNFL (p-RNFL) thickness changes after vitrectomy for epiretinal membrane (ERM). The relationship between p-RNFL thickness change and visual function was assessed. Methods. Thirty-five eyes from 35 patients with ERM who underwent vitrectomy with internal limiting membrane (ILM) removal were included. Average p-RNFL and the four quadrants thickness were measured by spectral-domain optical coherence tomography (SD-OCT) before and at one, three, and six months after surgery. Results. At six months after surgery, p-RNFL thickness of the temporal and inferior quadrant was decreased in the operated eyes compared with fellow eyes (p<0.05). Pattern standard deviation (PSD) was higher than that of fellow eyes (p = 0.002). The temporal and inferior quadrant p-RNFL thickness showed a relationship with both best-corrected visual acuity (BCVA) outcome and the six-month PSD (p<0.05, respectively). Conclusions. The selective decrease in the temporal and inferior p-RNFL thickness after vitrectomy for ERM removal could indicate inner retinal damage related to ILM peeling.     

黄斑部视网膜前膜的光学相干断层扫描图像特征

目的 :探讨黄斑部视网膜前膜的光学相干断层扫描 (opticalcoherencetomographyOCT)图像特征及临床诊断价值。方法 :对临床拟诊或诊断为黄斑部视网膜前膜患者 15例 15眼行OCT ,直接、间接检眼镜 ,眼底照相或FFA检查。结果 :黄斑部视网膜前膜的OCT图像表现为视网膜表面高反光带 ,厚薄不一 ,或紧贴于黄斑表面 ,或与其相连。绝大多数中心凹厚度增加。结论 :OCT可活体显示黄斑前膜 ,评价手术效果 ,为黄斑前膜的临床诊断提供了更加明确客观的信息     

特发性视网膜前膜患者的多焦视网膜电图改变

目的:应用多焦视网膜电图(multifocalelectroretinogram,mfERG)对正常对照眼和特发性视网膜前膜眼进行检测并比较两者之间的差异。方法:用VERISScience4.0视诱发反应图像系统对17例(20只眼)正常对照者和15例(19只眼)特发性视网膜前膜患者进行检测。结果:特发性视网膜前膜患者皆出现程度不同多焦视网膜电图异常,与正常对照组的比较显示视网膜前膜组1～6环的P1波反应密度值和1～6环的N1波潜伏期与正常对照组有显著性差异,视力与第一环振幅无相关但与第一环的潜伏期存在相关。结论:多焦视网膜电图可用于对特发性视网膜前膜患者进行视功能评估。     

Inner Macular Changes in Fellow Eye of Patients With Unilateral Idiopathic Epiretinal Membrane

PurposeWe evaluated a series of fellow eyes (FEs) in patients affected by unilateral idiopathic epiretinal membrane (IERM) with spectral-domain optical coherence tomography (SD-OCT) and OCT angiography (OCT-A) to determine if a previous defect in the inner retina is present before the mechanical damage to the inner limiting membrane (ILM) caused by posterior vitreous detachment.MethodsIn patients with IERM (N = 39), ganglion cell layer (GCL) thickness in FEs was assessed with SD-OCT; in a subgroup (N = 25) the vessel density (VD) at the superficial (SCP) and deep capillary plexus (DCP) was assessed with swept-source OCT-A (SS-OCT-A). These values were then compared with 30 age-matched healthy control eyes (CEs). The statistical analyses used SPSS software version 15.0 (SPSS, Inc., Chicago, IL, USA). Data collected underwent 1-way ANOVA. A level of P < 0.05 was accepted as statistically significant.ResultsThe GCL thickness in the FEs was significantly lower than in CEs, with a significant thinning in all sectors except temporal ones (mean P < 0.001, superior P = 0.0002, superonasal P < 0.001, inferonasal P < 0.001, and inferior P = 0.002). The VD was significantly lower in the FEs in all sectors of SCP (mean P = 0.009, inner ring P = 0.028, and outer ring P = 0.007).ConclusionsGCL and SCP are significantly reduced in the FEs. These data suggest that a vascular defect in the SCP could cause a cellular loss in the inner retina that may determine the cascade events leading to the IERM proliferation; the diagnosis in a preclinical phase could provide a treatment strategy to prevent the progression of the disease.     

抗血管内皮生发因子治疗后湿性AMD患者的OCT特征与视力相关性分析

目的 评价湿性年龄相关性黄斑变性(AMD)患者抗血管内皮生长因子(VEGF)治疗后术眼OCT参数与视力之间的相关性.方法 32例32只眼湿性AMD患者接受抗VEGF治疗后5-6月,记录患者最佳矫正视力,同一天进行频域OCT扫描,对黄斑中心凹厚度(FT),黄斑中心区厚度(CST),黄斑区容积(CV),黄斑区平均厚度(CAT),视网膜下液(SRF),视网膜内液(IRF),脉络膜新生血管膜厚度(CN-VMT)等参数进行分析,并根据成像质量进行手动校正,探讨术眼最佳矫正视力与OCT各参数之间的关系.结果 对32例患者的结果分析显示,在CST>210um的患者中,术眼最佳矫正视力(LogMar视力)与校正前后的FT、CV及CAT均无相关性;与校正前后的CST有相关性,相关系数分别为r=0.396,P=0.041;r=0.447,P=0.019,校正后的相关性更强.有视网膜内液组和无视网膜内液组的LogMar视力分别为1.14±0.54和0.64.4±0.49,两组差异有统计学意义(t=2.66 P=0.012). CNV显著组和CNV不显著组的LogMar视力分别0.98 4±0.61,0.57 4±0.34,两组差异有统计学意义(t=2.205 P=0.035).结论 湿性AMD患者抗VEGF治疗后最佳矫正视力(LogMar视力)与校正后的中心区厚度呈正相关.手动校正中心凹位置对正确判断AMD患者抗VEGF治疗的效果十分必要.     

The relationship between the visual prognoses of branch retinal artery obstruction and foveal thickness on OCT

Purpose

To determine the correlation between the prognosis of branch retinal artery obstruction (BRAO) and the foveal thickness or outer nuclear layer (ONL) thickness on optical coherence tomography (OCT).

Methods

Twenty-one eyes (21 patients) in patients with resolved, non-complicated BRAO and a normal control of 10 eyes (10 volunteers) were used in this study. The average macular thickness, foveal thickness and ONL thickness at central fovea were measured in both the patients and the control group using spectral domain OCT. The thickness between the patient group and the control group were compared and correlation between the best corrected visual acuity (BCVA) and each thickness was determined.

Results

The average age of the patients was 52 ± 5.8 years. The average macular thickness, foveal thickness and ONL thickness at the central fovea of the patients were significantly (p < 0.001, p = 0.023, p = 0.021, respectively) thinner than that of the control group. Both the foveal thickness (r_s = 0.56, p = 0.008) and ONL thickness (r_s = 0.86, p < 0.001) were significantly correlated with BCVA. There was no significant correlation between the average macular thickness and BCVA.

Conclusions

The foveal thickness and ONL thickness at the fovea was positively correlated with the BCVA in patients with resolved BRAO.     

孔源性视网膜脱离眼黄斑区光相干断层扫描 特征与视力预后的关系

目的观察孔源性视网膜脱离患者黄斑区组织形态学改变与手术后视力预后的关系。方法对39例孔源性视网膜脱离患者39只眼进行光相干层扫描（OCT）检查，根据OCT显示的黄斑区神经上皮层形态，分为神经上皮水肿（水肿组）、神经上皮层间分离（分离组）、神经上皮囊样变性（囊样变组）3组，对3组之间视网膜脱离时间、手术前后视力以及OCT检测的黄斑区神经上皮层厚度进行相关指数的秩和及多重比较检验。结果3组患者手术前视力比较，其差异均无统计学意义(P＞0.05)；手术后视力、视网膜脱离时间及神经上皮层厚度三方面的差异均有统计学意义(P＜0.05)。分离组与囊样变组患者在视网膜脱离时间及神经上皮层厚度方面比较，其差异有统计学意义(P＜0.05)，而手术后视力差异无统计学意义(P＞0.05)。结论视网膜脱离患者的视网膜脱离时间、手术后视力均与OCT检测的神经上皮层厚度有相关关系。视网膜脱离时间越长，脱离的黄斑区视网膜神经上皮层厚度增加，视网膜组织形态学改变越明显，手术后视力愈差。(中华眼底病杂志,2005,21:83-85)     

Foveal Thickness between Stratus and Spectralis Optical Coherence Tomography in Retinal Diseases

Purpose

To compare the foveal thickness (FT) parameters measured by Stratus optical coherence tomography (OCT) and Spectralis OCT in various retinal diseases and to construct conversion formulas between the two types of OCT devices.

Methods

We examined 366 consecutive patients (475 eyes) with retinal diseases and 13 normal controls (13 eyes). The patients were categorized into eight retinal disease groups. The mean amount and distribution of foveal thickness differences (FTD) measured by Stratus and Spectralis OCT were determined, and conversion formulas were constructed for Stratus OCT FT from Spectralis OCT FT for each retinal disease group.

Results

Among retinal diseases, the mean FTD was significantly larger in exudative age-related macular degeneration (AMD) patients (mean ± SD, 94.0 ± 55.0 µm) compared to normal subjects (66.2 ± 11.7 µm; p < 0.0001). The proportion of eyes with a mean FTD outside 1.96 standard deviations of normal subject FTD was greatest in the exudative AMD (50.0%) group and smallest in the macular hole (18.2%) group. The predicted FTs obtained through the conversion formulas showed lower variance than the actual FTD values, especially in the exudative AMD group. The prediction line for exudative AMD deviated most from that of normal subjects.

Conclusions

FTD shows diverse values and variances among various retinal diseases, especially in exudative AMD, which indicates that Stratus OCT FT cannot be predicted from Spectralis OCT FT by FTD value alone. We constructed statistically significant conversion formulas, which provided more reliable methods to predict Stratus OCT-measured FT from Spectralis OCT measurements for different retinal disease groups.     

3D光学相干断层扫描在特发性黄斑前膜诊治中的应用

目的应用3D光学相干断层扫描（OCT）观察特发性黄斑前膜（IMEM）的形态特征及其对视力的影响。方法应用3D—OCT观察42例（46只眼）IMEM患者的OCT图像,分析黄斑中心凹形态、中心凹厚度与视力的关系。结果在42例（46只眼）IMEM患者的3D-OCT图像中表现为黄斑区视网膜表面厚薄不一的高反光带,绝大多数伴不同程度的黄斑中心凹厚度增加,黄斑中心凹越厚,视力越差。34只眼（73．9％）OCT图像表现为与视网膜内层局灶性粘附的条带状强反光,大部分与视网膜内层分离,另12只眼（26．1％）表现为与视网膜内层完全紧密粘连的增强增宽的反光带。结论3D-OCT可以精确测量黄斑视网膜厚度,客观而全面地提供视网膜各层之间以及厚度变化的信息,从而初步评价IMEM与视力的关系,为IMEM提供更有参考价值的手术指征并指导手术操作。     

Idiopathic Macular Epiretinal Membrane Surgery and ILM Peeling: Anatomical and Functional Outcomes

Purpose: Evaluation of the visual and anatomical outcomes following idiopathic macular epiretinal membrane (ERM) removal, with or without internal limiting membrane (ILM) peeling, and review of the literature.

Methods: A retrospective study of 39 eyes operated for idiopathic ERM was conducted. Pars plana vitrectomy was combined with ERM removal and Indocyanine green (ICG) assisted ILM peeling in 24 eyes.

Results: In Group A (without ILM peeling), mean preoperative BCVA was 0.48 logMAR (0.3 in decimal units), whereas mean postoperative BCVA was 0.37 logMAR (0.4 in decimal units). In Group B (with ILM peeling), mean preoperative BCVA was 0.58 logMAR (0.25 in decimal units), whereas mean postoperative BCVA was 0.31 logMAR (0.5 in decimal units). No statistically significant difference was observed between Groups A and B regarding preoperative or postoperative BCVA (p>0.1, Student’s t-test).

OCT measurement of postoperative foveal thickness reveled a significant decrease in thickness in both groups; however, no correlation was observed between postoperative BCVA and postoperative foveal thickness (Pearson’s correlation coefficient?=?0.139; p>0.1).

Conclusions: In spite of final visual acuity improvement following idiopathic ERM removal, recovery of a normal foveal thickness is not achieved in the majority of the cases. ICG assisted ILM peeling does not affect the functional outcome of idiopathic ERM removal.