介入性输卵管再通术及碘化油应用初步研究

目的　探讨介入性输卵管再通术在治疗输卵管阻塞性不孕症的临床效果及碘化油的应用价值。方法　观察组 2 1例 42条输卵管阻塞。对照组 16例 3 2条输卵管阻塞 ,对照组仅行介入性输卵管再通术 ,观察组在再通术成功后向输卵管内注入超液态碘化油丁胺卡那霉素乳剂。所有病例 6个月后复查。结果　观察组与对照组的再通率、术后受孕率分别为 81.0 %、81.3 %;2 8.6%、2 5 %。术后再通输卵管粘连复发率观察组 5 .88%、对照组 2 6.9%,比较两者差异具有显著性意义 (x2 =6.3 6,Ρ <0 .0 5 )。结论　介入性输卵管再通术是治疗输卵管阻塞性不孕的一项有效方法 ,碘化油应用可明显降低再通术后输卵管粘连复发率     

介入性输卵管再通术结合中医治疗输卵管阻塞性不孕症的临床研究

目的探讨介入性输卵管再通术结合中医治疗输卵管阻塞性不孕症的临床应用价值.材料和方法对200例337条输卵管阻塞性不孕症患者,在电视透视下,用改进的导管、导丝进行输卵管再通术,其中120例再通术后行口服中药、中药灌肠及热敷治疗.结果337条阻塞输卵管中,再通276条,再通率为81.9%.2个月后子宫输卵管造影显示,单纯再通术的127条再通后的输卵管,68条再通良好,有效率为53.5%;配合中药治疗组的149条经再通后的输卵管,保持通畅良好112条,有效率为75.2%.术后随访1年,单纯再通术组受孕率为33.8%(27/80),配合中药治疗组的受孕率为56.7%(68/120).结论输卵管再通术结合中医治疗不孕症,方法简单安全,再通的有效率、受孕率均高于单纯输卵管再通术.     

改良式超选择性再通术治疗输卵管阻塞性不孕症的临床价值

目的：我国育龄妇女不孕症发生率约为6．8％-10．0％，其中20%-40％不孕症原因为输卵管阻塞，而传统的治疗方法是官腔加压输卵管通液，再通成功率较低。介入性超选择插管再通术由于其损伤小、操作简便。同时介入性输卵管再通术兼有选择性输卵管造影的价值．可清楚显示输卵管阻塞部位、形状及有无粘连、积水等情况．有助于鉴别输卵管阻塞的原因，为后续治疗提供有价值的资料。改良传统介入导入装置，用自制导管装置经超选择性输卵管造影（SSG）和输卵管再通术（FTR）治疗不孕症患者，研究手术操作、再通率、妊娠率等相关因素。     

介入性再通术治疗输卵管阻塞性不孕症的临床应用

目的 :研究介入性再通术治疗输卵管阻塞性不孕症的临床疗效和综合治疗技术。方法 :将同轴导管沿着特制角部定位导丝插入子宫角部 ,输卵管插管成功后 ,对阻塞段行导丝再通或高压推注法再通。在介入性再通术基础上结合中医活血化瘀法辅助治疗。结果 :再通率为 90 %。介入结合中医药组 66例 ,2 9例受孕 ,受孕率为 43 .9% ;单纯介入组42例 ,16例受孕 ,受孕率为 3 8.1% ,两组受孕率比较 ,P <0 .0 1,综合治疗组受孕率高于后者。对 10 8例患者利用特制钩形角部定位导丝行介入再通 ,插管成功率为 10 0 %。伞端再通成功率为 60 %。结论 :介入再通结合中医活血化瘀法综合治疗输卵管阻塞性不孕症 ,明显提高了临床疗效。     

介人性输卵管再通术联合腹腔镜治疗输卵管阻塞性不孕症的临床价值

目的 探讨介入性输卵管再通术联合腹腔镜治疗输卵管多发阻塞性不孕症的临床价值.方法 回顾性分析67例127条输卵管近段阻塞合并同侧伞端粘连不孕患者资料,行选择性输卵管再通术后2～3 d利用腹腔镜对粘连伞端行分离及造口术.分析输卵管近三段再通率、完全再通率,随访1年观察妊娠率及相关并发症等.对术后1年未妊娠者行输卵管造影复查.结果 67例均成功实施输卵管再通术,近三段再通率为97.6%(124/127);联合腹腔镜对近三段再通的124条输卵管行伞端微创手术治疗,完全再通率为98.4%(122/124).术后1年妊娠率为58.2%(39/67),异位妊娠发生率为4.5%(3/67),未妊娠率为37.3%(25/67),其中输卵管再阻塞未妊娠率为25.4%(17/67),输卵管通畅未妊娠率为11.9%(8/67).结论 介入性输卵管再通术联合腹腔镜是治疗输卵管多发阻塞性不孕症的有效方法,可有效提高妊娠率.     

用自制器械行选择性输卵管造影和再通术

报告用自制器械行子宫输卵管选择性造影及再通术45例,插管成功率95.5%。近端输卵管阻塞再通率80%。随访结果:15例患者正常受孕,受孕率33.3%,其中继发不孕症受孕率50%,原发不孕症受孕率17.4%。近端阻塞再通术后受孕率54.5%,远端积水或阻塞患者受孕率15%。显示选择性输卵管造影及再通术是治疗女性不孕症的有效方法;本手术最佳适应证为继发不孕、近端输卵管阻塞患者;自制器械价廉、安全。     

输卵管性不孕症的放射介入治疗评价

目的:评价放射介入再通术对输卵管性不孕症的疗效。方法:随访102例接受选择性输卵管造影(SSG)和介入性输卵管再通术(FTR)治疗的输卵管阻塞不孕症患者,统计术后1年内妊娠率、异位妊娠率及输卵管再阻塞率,并进行综合分析。结果:完全梗阻患者1年妊娠率为40.7%,其中近端(间质部、峡部)阻塞妊娠率为60%,中远端(壶腹部、伞端)阻塞妊娠率为16.67%,两者比较差异有显著性(χ2=5.19,P<0.05);不完全阻塞患者1年妊娠率分别为通而欠畅60.9%、通而不畅43.2%、通而极不畅13.3%。三者比较差异有显著性(χ2=8.40,P<0.05)。结论:SSG和FTR是治疗输卵管性不孕症的有效方法,输卵管近端阻塞为SSG和FTR首选。     

输卵管再通术联合中医治疗输卵管阻塞性不孕

目的　评价介入性输卵管再通术与中医药联合应用在治疗输卵管阻塞性不孕症方面的临床疗效。方法　对 38例输卵管阻塞性不孕病人的 76条输卵管,在DSA监视下,用Cook公司FTC-900输卵管再通系列器材进行输卵管阻塞再通术,手术前、后均辅以中医药侧穹隆封闭、灌肠治疗。结果　76条阻塞的输卵管中有 71条获得疏通,有效率为 93. 4%;术后随访半年, 38例不孕病人中有 25人受孕,受孕率为 67. 3%; 13例未受孕者中,有 8例出现输卵管的再阻塞。结论　输卵管再通术与中医药联合应用,简便安全,输卵管疏通率、术后受孕率均高于单纯行输卵管再通术或中医药治疗的病例,值得推广应用。     

选择性子宫输卵管造影与再通术对阻塞性不孕的诊疗价值

目的探讨选择性子宫输卵管造影与再通术对输卵管阻塞所致不孕的诊疗价值。资料与方法回顾性分析200例女性不孕症患者,年龄20～42岁,平均不孕年限为3.8年,均行选择性子宫输卵管造影与再通术后跟踪观察1年,观察诊疗效果。结果 200例396条输卵管中294条显示不同程度的阻塞,再通成功212条,再通成功率为81.2%,126例患者双侧或单侧再通成功,1年内成功正常受孕46例,占再通成功病例的36.5%。结论选择性子宫输卵管造影对输卵管阻塞所致不孕症具有较高的诊断价值,再通术对输卵管阻塞所致不孕症有一定的治疗价值。     

介入性输卵管再通术与输卵管加压通液治疗输卵管阻塞的比较

目的 使用介入性输卵管再通术治疗输卵管阻塞性不孕症，观察治疗效果，并与输卵管加压通液治疗本病的效果进行比较。方法 选观察组18例，输卵管36支；对照组10例，输卵管20支。观察组行选择性输卵管再通术，对照组仅用输卵管加压通液治疗。所有病例6个月后复查。结果 再通成功率观察组61．1％（22／36），对照组30．0％（6／20）。两者比较差异具有显著性意义（P＜0．05）。再复发者观察组4支，对照组1支。结论 介入性输卵管再通术疗效显著优于传统输卵管加压通液治疗，该技术操作安全简单、成功率高，应作为治疗输卵管阻塞的首选方法。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.