Precocious puberty in a female with Proteus Syndrome

Proteus syndrome is a complex disorder comprising malformations and overgrowth of multiple tissues and characterized by its polymorphism and mosaicism. The syndrome is rare and sporadic. Oliveira M da C et al reported the first case of Proteus syndrome associated with precocious puberty in a boy. We are reporting a case of a 7-month old girl with Proteus syndrome who developed a juvenile granulosa cell tumor in one ovary causing precocious puberty. At our knowledge this is the first case of Proteus syndrome with precocious puberty in a female.     

松果体区肿瘤的全切除

目的：探索松果体区肿瘤全切除的可行性及技术要点。方法：回顾性分析该院１９８６年３月至２０００年５月收治并手术的７０例松果体区肿瘤患者的诊治及预后情况。结果：手术采用侧脑室入路１８例,Ｐｏｐｐｅｎ入路３５例,Ｋｒａｕｓｅ入路１７例;病理诊断胶质瘤２１例,生殖细胞瘤１４例,脑膜瘤７例,畸胎瘤７例,胆脂瘤６例,胶质增生４例,皮样囊肿３例,脑膜囊肿２例,蛛网膜囊肿２例,脊索瘤、血管畸形、垂体腺瘤、Ｇａｌｅ     

松果体区肿瘤围手术期护理

目的：总结松果体区肿瘤围手术期护理的经验。方法：对26例松果体区肿瘤显微手术切除患者进行了统计和分析。结果：26例患者术后无死亡和重残,3例后期复发。结论：加强松果体区肿瘤围手术期护理,尤其是脑积水的护理是手术成功与康复的关键。     

松果体区乳头状肿瘤临床病理分析

目的:探讨松果体区乳头状肿瘤的临床病理学特征、免疫表型、诊断和鉴别诊断。方法:对1例松果体区乳头状肿瘤进行HE和免疫组化染色,并复习相关文献。结果:组织学上肿瘤富于细胞,瘤细胞排列成片状和乳头状。乳头中央为宽阔的纤维血管轴心,表面被覆一层或几层肿瘤细胞,部分血管壁玻璃样变性。可见灶性坏死。瘤细胞呈上皮样,细胞界限清楚,胞质空淡或淡嗜伊红,核圆形、卵圆形,染色质颗粒状,核仁小,核分裂像高达10个/10HPF。免疫组化标记,肿瘤细胞弥漫表达CK、NSE,CK18局灶阳性,Ki-67增殖指数为10%,而GFAP、CgA、Syn、S-100蛋白阴性。结论:松果体区乳头状肿瘤是一种罕见的颅内肿瘤,组织学最显著特征是肿瘤呈上皮样生长模式,光镜下不易与乳头状室管膜瘤、脉络丛肿瘤及转移性乳头状癌等鉴别,应用免疫组化标记可有助于鉴别诊断。     

Recurrent intermittent small bowel obstruction due to carcinoid tumor

We encountered an unusual case of carcinoid tumor of the terminal ileum with intermittent recurrent small bowel obstruction of seven years' duration rather than the usual presentation of chronic progressive obstruction.     

不同入路显微手术治疗松果体区肿瘤临床分析

目的探讨显微手术治疗松果体区肿瘤的手术入路及手术技巧。方法收集该院2016年3月至2019年3月显微手术治疗的42例松果体区肿瘤患者的临床资料进行回顾性分析。结果42例松果体区肿瘤患者全切除33例,次全切6例,部分切除3例。术后临床症状消失或好转38例,病情加重2例,脑积水加重2例,无视野缺损、硬膜外血肿及死亡病例,以上4例患者经过保守治疗,临床症状均缓解出院。结论根据松果体区肿瘤的大小、部位以及手术者手术习惯合理选择手术入路,是完全切除松果体区肿瘤的关键;同时重视术后可能出现的并发症是保证手术成功的重要措施。     

Cutaneous human myiasis due to Dermatobia hominis

This is a case report of cutaneous myiasis due to Dermatobia hominis in a female physician who had travelled to Belize. Cutaneous myiasis is endemic in Central and South America but is seldom reported from the Caribbean islands.     

脑肿瘤卒中的发病机制与MRI表现

目的 提高对脑肿瘤卒中MRI特点的认知。方法 分析对照21例33个脑肿瘤卒中病灶和28例单纯性脑内血肿的MR表现，观察血肿的MR信号，周围水肿，含铁血黄素沉积圈和增强表现。结果 33个脑肿瘤卒中MR信号不均匀25个（75.6%），周围水肿持续存在33个（100%）、水肿范围扩大26个（78.8%），含铁血黄素沉积圈不规则、离散、零乱、厚度不均匀28个（84.8%），离散、零乱、厚度不均匀28个（84.8%），增强扫描31个病灶内可铜陵强化影（93.9%），而单纯性脑内血肿的MR信号有一定的规律性、周围水肿在慢性期后减少或消失，含铁血黄素沉积圈规则、完整、厚度均匀，增强扫描表现为急性期无强化，亚急性期，浸性期呈环状强化。结论 脑肿瘤卒中血肿的MR信号。周围水肿，含铁血黄素沉积圈以及增强扫描表现具有特征性，可以作为其诊断依据。     

恶性肿瘤所致全血细胞减少的病因探讨

目的分析肿瘤致全血细胞减少的病因，以提高对此类疾病的认识，减少误诊。方法对262例初诊时全血细胞减少患者的临床资料进行回顾性分析。结果262例肿瘤患者中，急性白血病的比例最高，为145例，占55．34％，其次为肝癌34例占12．98％．多发性骨髓瘤（7．64％），其余依次为胃癌，恶性淋巴瘤、恶性组织细胞病，结肠癌、乳腺癌，胰腺癌，卵巢癌。结论全血细胞减少多见于在造血系统、消化系统、生殖系统恶性肿瘤。在分析肿瘤致全血细胞减少时，注意不仅仅是急性白血病所致，应详细采集病史，全面检查，提高全血细胞减少的病因诊断，避免误诊、漏诊。     

Left internal jugular vein thrombosis due to a lung tumor

Deep vein thrombosis is a common disease among Caucasians but is rare in Asia. Venous thrombosis may be fatal, for example by a pulmonary embolism and right or left atrial thrombosis. Alternatively, deep vein thrombosis may follow a benign pattern such as femoral and popliteal vein thrombosis. Theories abound regarding the causes of deep vein thrombosis, with the most common theories being long-term stasis and lack of exercise. Internal jugular vein thrombosis is a rare but potentially fatal disease with various causes. In the pre-antibiotics era, this disease was frequently associated with deep neck infection. Recently however, local trauma, central catheterization, and repeated intravenous injections with drugs have become the leading causes of thrombosis. Spontaneous internal jugular vein thrombosis may occur in connection with a neoplasm, termed Trousseau's syndrome. This investigation reports a case of lung cancer associated with internal jugular vein thrombosis.     

松果体区肿瘤的诊断和治疗--附30例报告

目的 探讨松果体区肿瘤的诊断和治疗方法。方法 回顾性分析30例松果体区肿瘤的临床资料。结果 16例(53．3％)经组织学诊断,其中生殖细胞瘤12例(75％)。3例手术部分切除,27例行脑室分流减压术,l3例行立体定向活检。2例先行立体定向内照射,全部病例均给予常规外照射。5例(16．7％)颅内种植性播散,7例(23．3％)松果体区局部复发,未发现脊髓转移。1、3、5、10年生存率分别为93．3％(28／30)、83.3％(25／30)、70．0％(21／30)、52．1％(12／23)。结论 对不能取得组织学诊断的松果体区肿瘤,可依据临床和影像学表现来诊断。常规放射治疗仍然是多数松果体区肿瘤主要的治疗手段,且疗效较好。