Self-Reported Quality of Life for Patients with Progressive Neurological Diseases

Progresssive neurological diseases influence the life situation of patients either totally or partially. Such patients' own ratings of their life situation and well-being were made using a health-related quality of life HRQoL instrument called Quality of Life: status and change (QLsc). In general the interviewees rated their life domains in terms of positive response alternatives and no subgroups were found, e.g. with the same diagnoses, periods of sickness or age. The results suggest that the interviewees' experience of quality of life (QoL) is subjective and individual. The interviewees who had been to the rehabilitation centre several times rated their quality of life, in terms of positive response alternatives for the items covering overall experiences of bodily health, well-being and their whole life as well as for items in the social domain, to a greater extent than those who were visiting it for the first time. This revised version was published online in June 2006 with corrections to the Cover Date.     

路径式早期康复护理对脑梗死患者神经功能和生存质量的影响

目的 探讨路径式早期康复护理对脑梗死患者神经功能和生存质量的影响.方法 选取我院2019年2月至2020年2月收治的脑梗死患者94例,随机分为对照组与实验组各47例.对照组行常规护理,实验组行路径式早期康复护理.比较两组的神经功能及生存质量.结果 护理前,两组的NIHSS评分比较无统计学差异(P>0.05);护理后,两...     

综合治疗重症急性胰腺炎患者的生存质量及其精神健康相关影响因素的研究

目的探讨综合治疗重症急性胰腺炎患者的生存质量,并对相关精神健康影响因素进行分析。方法入选2010年1月至2012年12月我院进行综合治疗的重症急性胰腺炎患者65例,设为观察组,同时选取55例同期常规治疗患者作为对照组,应用SF-36和SAS量表进行调查,分析其生存质量及精神健康相关影响因素。结果 SF-36量表评估中,观察组在生理机能、社会功能和精神健康三个维度的得分明显高于对照组,差异具有统计学意义(P<0.05);对影响焦虑的相关因素进行多元回归分析后,发现并发症、住院经历和疾病了解情况对焦虑影响较明显(P<0.05)。结论综合治疗的SAP患者与采用常规疗法的患者相比,出院后的生存质量较好,值得在临床进行推广。     

Evaluation of Quality of Life of Adult Cancer Patients Attending Tikur Anbessa Specialized Referral Hospital,Addis Ababa Ethiopia

Background

Little is known about the quality of life of cancer patients in the Ethiopian context. This study evaluated quality of life of cancer patients in Ethiopia.

Methods

A cross-sectional study was conducted in Addis Ababa University Tikur Anbessa Specialized Referral Hospital Addis Ababa, Ethiopia (TASRH) from March to May 2013. A total of 388 cancer patients were included. Translated in to Amharic, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QOL C-30) was used to measure Quality of life (QoL). The data was analyzed with SPSS Version 17.0.

Results

Among the participants, 251(64.7%) were men and 138(35.6%) were below the age of 40 years. Large proportion of patients were diagnosed with breast cancer, 114(29.4%), and cervical cancer, 102(26.3%), and the clinical stages during the beginning of therapy were at stage II a 133(34.3%). The mean of global health status/QoL was 57.28 (SD= 25.28). Quality of life was found to be associated with some functional scales as role functioning, P≤0.001, social function, P=0.00, and symptom scales as pain, P=0.00, loss of appetite, P=0.004, and financial impact, P=0.02, but no associations were noted in relation to socio demographic characteristics.

Conclusions

Quality of life assessments should be included in patient treatment protocols to improve their quality of life since being a cancer patient may be associated with a high level of impairment in different aspects of life.     

社区卫生服务中心糖尿病患者的生命质量评价

目的 评价珠海市香洲区社区卫生服务中心的糖尿病患者的生命质量,探讨影响生命质量可能的危险因素.方法 选取香洲区9个社区卫生服务中心,采用和<糖尿病患者特异性量表>,应用横断面调查的方法对196名糖尿病患者进行询问式问卷调查.结果 糖尿病对患者生命质量的影响主要反映在总体健康、躯体角色功能和情绪角色功能3个维度.影响患者生命质量的综合因素主要是:年龄、运动疗法、财产或收入减少、爱生闷气、遵医嘱服药或治疗、容易紧张、胰岛素治疗.两个量表具有一定的相关性.结论 在采取综合治疗糖尿病患者时,应着重加强患者的心理支持、精神疏导,给患者更多的关怀;同时应努力提高患者对疾病的认识水平及自我保健意识.     

原发性肝癌生命质量量表的制定与评价

目的:研制原发性肝癌患者生命质量量表,并对量表考评。方法:依据疾病特异生命质量量表发展引导程序,发展肝癌病人生命质量量表。抽取158名病人作为量表考评调查对象,以检验量表信度、效度和反应度。结果:形成的肝癌生命质量量表(LC2.0)包括4个功能子量表、3个症状子量表和4个单项症状条目共32个评价条目。量表的重测相关系数、Cronbach'sα系数、分别为0.902、0.922。因子分析结果显示,量表结构与理想构想相符。本量表能判别不同病情等级病人生命质量差异。结论:FLC2.0可信、有效、敏感,应用于临床,能为不同患者的治疗提供指导;也可作为医疗技术的效果和卫生服务的效益评价。     

Multiple Chronic Health Problems are Negatively Associated with Health Related Quality of Life (HRQoL) irrespective of Age

Purpose: To examine HRQoL measured by EORTC QLQ-C30 with respect to an increasing number of self-reported chronic health problems in the general Swedish population and to study the association between HRQoL, chronic health problems and age, gender, income, marital status and employment status. Method: A postal survey among a large random sample of 4000 adults aged 18–79 years. The study material contained EORTC QLQ-C30 core questionnaire supplemented by a sociodemographic questionnaire including questions about 13 chronic health problems of which four categories, `No', `Few', `Some' or `A lot of' chronic health problems were constructed. Results: Multiple chronic health problems were significantly associated with reduced HRQoL. The increased number of chronic health problems was also associated with age. When the number of chronic health problems was accounted for, the influence of age diminished. Low income and unemployment were associated with greater decline in HRQoL with respect to increasing number of problems among the respondents in working age. Conclusion: The impact of increased number of chronic health problems had varying consequences in different age groups. Moreover, sociodemographic and economic factors showed to interact differently with chronic health problems and HRQoL in various age groups. It appears from our results that an assessment and a careful consideration of these factors will be valuable in order to facilitate the interpretation of the effects of cancer and treatment on long-term HRQoL of cancer patients. This revised version was published online in June 2006 with corrections to the Cover Date.     

Negative Mood and Quality of Life in Patients with Asthma

The aim of this study was to evaluate the effect of negative mood states at the moment of questionnaire, and other patient and disease characteristics on quality of life (QoL) in patients with asthma. The study groups were composed of 116 stable adult asthmatic patients and 116 age and sex matched healthy subjects. We used Short-Form Health Survey-36 (SF-36) for the assessment of general QoL in all participants, and the Asthma Quality of Life Questionnaire (AQLQ) for the assessment of disease specific QoL in patients with asthma. We evaluated negative mood in all subjects with a questionnaire including six mood subscales in three categories (nervous-anxious, hostile-angry and fearful-panicky). Negative mood scores were not different between asthmatic and comparison groups (p=0.4), but both SF-36 Physical Component Summary (PCS) and Mental Component Summary (MCS) scores were significantly lower in asthmatic group (p=0.003 and p=0.001, respectively). Multiple linear regression analysis in all study population indicated that both reduced PCS and MCS scores of SF-36 were associated with negative mood score (β=−0.28, p<0.001 and β=−0.37, p<0.001, respectively) and with FEV₁% (β=0.19, p=0.001 and β=0.25, p<0.001, respectively) after adjusting for age, female sex, and the presence of asthma. On the other hand, multiple linear regression analysis in patients with asthma revealed that negative mood score and disease severity score were significant predictors for overall score of AQLQ after adjusting for other patient and disease characteristics (β=−0.17, p=0.008 and β=−0.64, p<0.001, respectively). The level of negative mood and disease severity in asthmatics significantly impair QoL. Thus, considering that one of the main objectives of health care should be preserving a satisfactory QoL in asthmatics, the presence and seriousness of negative mood and their effects on QoL should be taken into account as part of the clinical evaluation in asthmatics.     

2006年山西省部分煤矿接尘工人生存质量及其影响因素分析

[目的]了解煤矿接尘工人的生存质量及其影响因素,为制订有针对性的提高矿工生存质量的干预措施,提高生存质量提供科学依据。[方法]2006年,应用世界卫生组织QOL-BREF量表对山西省2个煤矿部分接尘工人的生存质量进行测试。[结果]测试305名,其生存质量生理、心理、社会和环境4个领域得分均低于常模(P<0.01)。多元回归方程为Y生理因素=15.684 0.539学历-1.267日工作时间-0.796家庭摩擦-0.607工作危险程度 0.277食欲-0.619健康问题;Y心理因素=16.028-0.515工种-0.510福利满意-1.049健康问题 0.426食欲-0.989工作危险程度 1.325兴趣爱好广泛 0.637吸烟-0.381呼吸道症状-0.735独生-1.551同居;Y社会领域=15.739-1.490工作时间-1.138福利情况 0.672学历-0.928来自城镇-1.731来自市区;Y环境领域=17.363-0.808工种-1.524日工作时间-0.734福利情况-1.182工作危险程度-0.772健康问题0.343食欲-0.373社会地位0.612吸烟-0.615饮酒。[结论]山西省测试的煤矿接尘工人生存质量低于常模,影响其生活质量的因素主要是健康问题、日工作时间、工作危险程度、食欲、福利满意情况、家庭摩擦影响、学历、是否吸烟、是否独生、体检情况和兴趣爱好是否广泛。     

医疗介护模式对晚期消化道肿瘤患者生活质量的影响

目的通过实施医疗介护模式,延伸医院的医护服务,提高晚期消化道肿瘤患者的生活质量。方法入选2010年5月至2011年5月我院肿瘤科病房出院的晚期消化道肿瘤患者162例,其中对照组78例,观察组84例,所有患者随访2个月。分别在出院时及出院后1个月、2个月,采用KPS量表、癌症疼痛综合治疗生存质量量表及巴氏指数量表对患者进行测评。结果出院后1个月及出院后2个月,观察组的KPS评分明显高于对照组(P<0.05),癌症疼痛综合治疗生存质量评分亦明显高于对照组(P<0.05);而观察组的ADL评分在出院后1个月及出院后2个月低于对照组(P>0.05)。结论实施医疗介护模式可以减轻晚期消化道肿瘤患者的疼痛,改善患者的体能状态,提高患者的生活质量。     

社区健康管理下的糖尿病患者生命质量评价

目的 了解社区健康管理下糖尿病患者的生命质量及其影响因素.方法 采用糖尿病患者生命质量测定量表[QLICD-DM(V2.0)]对患者的生命质量进行评价并分析其影响因素.结果 QLICD-DM(V2.0)各模块得分从高到低依次为特异模块、社会功能、心理功能、生理功能.生理功能的影响因素有性别、治疗方法、治疗效果和家庭经济...     

Assessing Quality of Life in Adult Cancer Survivors (QLACS)

This article describes development of a quality of life measure designed to assess issues relevant to long-term cancer survivors. In-depth semi-structured interviews were conducted with 58 long-term cancer survivors to identify domains most relevant to long-term survivors ( 5 years post-diagnosis). Self-report items were developed from these interviews and administered to a second sample of 242 long-term survivors. Domains and items were selected from the item pool by a combination of factor analysis and criterion-based item selection. Five cancer-specific domains were identified (appearance concerns, financial problems, distress over recurrence, family-related distress, and benefits of cancer) along with seven generic QOL domains (negative feelings, positive feelings, cognitive problems, sexual problems, physical pain, fatigue, and social avoidance). Cronbachs was 0.72 or greater for each domain. Correlations between domain scores and criterion measures were 0.72 or higher in all but one generic domain (social avoidance), but somewhat lower on cancer-specific domains. The new multidimensional measure has good internal consistency and validity and is appropriate for comparisons between cancer and non-cancer populations, as well as long-term follow-up of cancer patients.     

原发性高血压患者生命质量影响因素

目的探索影响原发性高血压患者生命质量的因素。方法运用横断面调查研究方法对644例原发性高血压患者进行问卷调查,运用中文版SF-36量表测定生命质量,对影响因素进行方差分析和线性逐步回归分析。结果多因素分析结果显示,年龄、近1a内有无精神创伤、家庭收入、体育锻炼、对疾病的态度、防治知识知晓状况、平时血压控制情况以及社区综合管理等因素影响高血压患者的生命质量,标准偏回归系数分别为-0.204,-0.097,0.102,-0.174,-0.197,0.129,-0.178,-0.227。结论医生在治疗或管理高血压患者时,应有效控制血压,加强健康教育,指导患者进行适宜的体育锻炼,采取心理疏导,改善悲观心理,以提高患者的生命质量。     

脑卒中患者生命质量及影响因素分析

目的分析影响脑卒中患者生命质量的因素,为提高患者生命质量、临床护理干预提供依据。方法运用便利抽样的方法选取2017年1—10月在十堰市某三甲医院神经内科住院的138例脑卒中患者进行问卷调查,采用一般情况调查表和脑卒中生命质量量表(Stroke Specific Quality of Life Scale,S-SQOL)调查脑卒中一般情况和生命质量现况得分,采用单因素和多元线性回归,分析影响脑卒中患者生命质量的相关因素。结果138例脑卒中患者SQOL得分为153.35±46.44分,缺血性脑卒中SQOL各维度及总分得分均高于出血性脑卒中,除家庭角色、社会角色、思维、视力维度4个得分差异无统计学意义外(P>0.05),其他8个维度及SQOL总分差异均有统计学意义(P<0.05)。单因素分析显示,患者年龄(F=3.884,P=0.023)、文化程度(F=4.032,P<0.001)、职业(F=3.170,P=0.011)、家庭月收入(F=10.710,P<0.001)和伴随疾病(F=8.815,P=0.011)与脑卒中患者的生命质量有关;多因素分析显示,影响脑卒中患者生命质量的因素有年龄、职业、家庭月收入和自理能力。结论脑卒中患者生命质量得分较低,患者社会经济因素、自理能力是影响其生命质量的重要因素。     

家庭教育对出院精神分裂症患者生活质量及社会功能的影响

目的探讨影响出院精神分裂症患者生活质量的因素,对患者及家属进行相应的家庭教育,提高患者的生活质量和社会功能。方法将康复出院精神分裂症患者随机分为干预组与对照组,对干预组制订个体化的康复训练计划,对其家属实施为期3个月的家庭教育,随访1年后,应用生活质量综合评定问卷对干预组及对照组进行评定。结果干预组的总体生活质量及躯体功能、心理功能、社会功能均较对照组好,物质生活方面两组无显著性差异。结论精神分裂症患者的生活质量涉及到心身健康多个方面,家庭教育有助于增进患者自我照顾能力,减缓精神分裂症患者的功能衰退,提高生活质量和社会功能。     

心脏康复综合管理对经皮冠状动脉介入治疗术后患者生命质量的影响

目的探讨心脏康复综合管理应用于行经皮冠状动脉介入(PCI)治疗患者的效果。方法选取本院2018年7月至2019年3月收治的106例接受PCI治疗的患者随机分为两组各53例。对照组在PCI术后给予常规管理,实验组在对照组基础上加强心脏康复综合管理,比较两组患者的干预效果。结果干预3个月后,两组的6分钟步行试验(6MWT)距离均较干预前显著增加,且实验组的6MWT距离显著高于对照组(P<0.05)。干预后,实验组的各项生命质量评分均显著高于对照组(P<0.05)。结论对于行PCI治疗的患者,术后实施心脏康复综合管理可显著改善患者的运动能力,提高患者的生命质量。     

癫痫患者生命质量测定量表特异模块研制中的条目筛选

目的研制适合我国癫痫患者的生命质量测定量表(QLICD-EP)的特异模块,为形成完整量表打下基础。方法通过文献和核心小组讨论相结合的方法构建条目池,并对条目进行初步筛选、评价和修改形成初步量表。随机抽取31名癫痫病人和20名医生进行问卷调查和访谈,采用变异度法、相关系数法、因子分析法、克朗巴赫系数法、病人重要性评分、医生重要性评分对结果进行分析,结合核心小组讨论对条目进行再筛选。结果按上述6种统计方法选出12个条目,通过专家讨论最终得出10个条目作为癫痫患者生命质量量表特异模块的条目。结论按严格的程序选出的10个条目有较好的内容效度和代表性,适用于推广应用。     

癫痫患者生命质量测定量表特异模块研制中的条目筛选

目的研制适合我国癫痫患者的生命质量测定量表(QLICD-EP)的特异模块,为形成完整量表打下基础。方法通过文献和核心小组讨论相结合的方法构建条目池,并对条目进行初步筛选、评价和修改形成初步量表。随机抽取31名癫痫病人和20名医生进行问卷调查和访谈,采用变异度法、相关系数法、因子分析法、克朗巴赫系数法、病人重要性评分、医生重要性评分对结果进行分析,结合核心小组讨论对条目进行再筛选。结果按上述6种统计方法选出12个条目,通过专家讨论最终得出10个条目作为癫痫患者生命质量量表特异模块的条目。结论按严格的程序选出的10个条目有较好的内容效度和代表性,适用于推广应用。     

女性不孕症患者生活质量影响因素的研究现状

不孕症（infertility）是一种特殊的生殖健康缺陷性疾病,严重影响着患者的生活质量。关于不孕症对生活质量的影响因素是多方面的,包括社会人口学（年龄、教育程度、经济状况、职业、居住地、不孕类型、不孕年限）、生活习惯、人格、躯体状况、心理因素、家庭因素、社会支持等。近来研究结果发现,女性不孕患者生活质量与教育程度、经济收入、职业地位、不孕年限、生活习惯、生理和心理状态、社会支持呈正相关,而与居住地为农村、继发性不孕、内向性格、家庭关系较差呈负相关。对多种影响因素的研究现状和进展加以综述分析,以期能够指导医护人员在工作中重视不同影响因素以及患者的个体差异,为开展相关研究及促进女性不孕症患者及时就医提供依据,从而提高患者对治疗的耐受力,改善其生活质量。     

中国西部农村居民健康相关生命质量研究

利用“中国农村互助医疗社会实验研究”项目的资料,采用欧洲五维度健康量表(EQ-5D量表)对西部农村居民的健康相关生命质量(HRQOL)进行测量,分析农村居民健康相关生命质量的分布特征,探索农村居民HRQOL的潜在影响因素。主要结果包括:西部农村居民HRQOL相对较低,VAS(健康指数)为67.2;疼痛/不舒服和焦虑/沮丧是西部农村居民HRQOL方面存在的主要问题;年龄、文化程度和社会资本是影响农村居民HRQOL的主要潜在因素。研究根据以上结果提出了提高西部农村HRQOL的策略和措施,为制定农村卫生政策提供依据。