脉冲组织多普勒显像评价原发性高血压患者右室舒张功能

目的:应用脉冲组织多普勒显像(TDI)评价原发性高血压(EH)患者的右室舒张功能。方法:53例Ⅰ~Ⅱ级EH患者(EH组)及50例健康志愿者(对照组)于三尖瓣环与二尖瓣环行脉冲TDI检查,测量舒张早期峰值运动速度(e)、舒张晚期峰值速度(a),计算e/a。对比2组右室舒张功能参数,分析右室舒张功能参数与其他因素的相关关系。结果:EH患者三尖瓣环e明显减低,e/a明显下降,右室等容舒张时间延长,右室舒张功能参数与左室舒张功能参数呈紧密正相关。结论:轻、中度EH患者存在右室舒张功能障碍,两侧心室充盈参数之间相关性良好。脉冲TDI用于评价EH患者右室舒张功能是可行的。     

用超声多普勒研究高血压病左、右心室舒张功能

用超声多普勒研究高血压病左、右心室舒张功能方安娜劳婷香方苏芳（上海警备区８５医院心内科上海２０００５２）关键词高血压心室功能舒张超声心动描记术，多普勒作者用超声多普勒对４２名高血压病人及３３名年龄、心率、性别匹配的对照组进行研究，旨在评价高血压病患者...     

多普勒超声心动图评价小儿支气管哮喘时右心舒张功能

应用多普勒超声心动图测定了５５例支气管哮喘患儿和４１例正常小儿的右心舒功能各指标进行对照。结果表明：正常和支气管哮喘患儿的右心舒张功能各指标有显著性差异；婴幼儿哮喘与儿童哮喘的右心舒张功能仅部分指标差异有显著性；重型较轻型支气管哮喘者右心舒张功能显著下降。提示：①支气管哮喘时患儿存在右心舒张功能异常，且随着病情的进展，其右心舒张功能显著下降；②年龄对支气管哮喘患儿心脏功能的影响不明显。③多普勒超声     

多普勒组织成像和组织追踪技术对正常人心室长轴功能评价

目的探讨正常人左、右心室长轴功能的变化,为临床心脏功能评价提供正常值参考。方法应用脉冲多普勒组织超声技术和组织追踪技术观察110名正常成年人二尖瓣环和三尖瓣环不同位点,收缩峰值速度（Sm）,舒张早期峰值速度（Em）、舒张晚期峰值速度（Am）、Em/Am比值和各位点位移（D）的平均值,比较不同年龄组多普勒组织速度和位移,分析其变化规律和特点。结果二尖瓣环各位点Sm和D随着年龄段的增加而显著降低,左心室前壁和侧壁Sm和D高于其它位点,二尖瓣环平均Sm与年龄和左心室射血分数（LVEF）显著相关;二尖瓣环各位点Em和Em/Am随年龄明显降低,平均Em降低的年龄段比二尖瓣舒张早期充盈速度（E峰）早;三尖瓣环Sm与年龄无关,Em和Em/Am随年龄而明显降低。结论二尖瓣环和三尖瓣环多普勒组织速度和位移随年龄出现不同的变化特点,多普勒组织成像对舒张功能变化比传统超声心动敏感。     

M型彩色多普勒超声评价左室舒张功能的进展

用 M型彩色多普勒 （CMD）测量的左室舒张早期血流传播参数与 IVRT和 - dp/dtmax有明显的相关性 ,与脉冲多普勒 E/A比率相比 ,CMD没有假性正常。研究表明 :CMD能准确反映左室舒张功能的变化 ,是一种无创评价左室舒张功能的新方法。     

二尖瓣环多普勒组织成像和M型超声检查对左室舒张功能的评价

目的：探讨二尖瓣环的多普勒组织成像（DTI）和瓣环的M型超声运动曲线评价左室舒张功能的作用。方法：分别检测左室心肌肥厚组（20例）和正常对照组（25例）二尖瓣环的DTI运动频谱的收缩期峰值速度（Spv）、舒张早期峰值速度（EDpv）和心房收缩期峰值速度（ASpv）及瓣环M型运动曲线的运动总振幅（Td）、舒张早期振幅（EDd）和心房收缩期振幅（ASd），比较瓣口的多普勒血流频谱。结果：左心室肥厚组与正常组比较，EDpv明显减小（7．5对13．8cm／s．P〈0．01），EDpv／ASpv值明显减小（0．70对1．41，P〈0．01），Spv／EDpv值明显增大（1．62对0．96．P〈0．01）；EDd值减小（12．0对16．3mm，P〈0．05），ASd值增大（10．1对7．5mm，P〈0．05）；正常组中，EDpv及EDpv／ASpv随年龄的增加而减小。20例LVH中二尖瓣口血流E／A〉1的有6例，其中5例DTI的EDpv／ASpv〈l。结论：二尖瓣环的DTI运动频谱和瓣环的M型超声运动曲线对评价左室的舒张功能有较大的价值。     

脉冲多普勒超声心动图评价33例糖尿病患者的左室舒张功能

本文应用脉冲多普勒超声心动图（PDE）评价无心脏病和充血性心力衰竭的33例糖尿病（DM）患者的左室舒张功能（LVDF）,并与33例健康人对比。发现DM患者的峰值速度E（PVE）E/A和充盈分数（FF）值明显低于对照组;而峰值速度A（PVA）和等容舒张时间（IRT）值则明显高于对照组,两组差异具有非常显著性（P<0.01）。表明DM患者LVDF下降,主要为左室舒张性减退,而顺应性未见明显异常。     

组织多普勒显像技术检测缺血心肌的局部舒张功能

目的 :评价组织多普勒显像 （TDI）技术检测缺血心肌局部舒张功能的价值。方法 :应用超声心动图分别记录心肌缺血组 （2 8例 ）和对照组 （30例 ）舒张期二尖瓣血流频谱 （TMF）及左室基底部、中部和心尖部 3个水平面 15节段心肌 TDI。结果 :两组间左室射血分数相近 （6 2 %± 9% vs 6 6 %± 8% ,P>0 .0 5 ）。心肌缺血组与对照组比较 ,TMF舒张早期减速度时间 （2 82± 17m s vs 2 0 1± 11m s,P<0 .0 5 ）和等容舒张时间 （92± 18ms vs 6 1± 10 m s,P<0 .0 1）延长 ;E/A比值增加 （0 .6 7± 0 .2 vs 1.6± 0 .5 ,P<0 .0 1）。对照组 TDI示左室基底部与中部心肌舒张早期舒张速度 （Em ）高于心尖部 （P<0 .0 5 ） ,缺血节段 Em降低 ,局部早期舒张减速度时间和等容舒张时间延长。结论 :TDI可无创检测左室局部舒张功能。     

组织多普勒技术对美托洛尔治疗前后的左室舒张功能的评价

目的应用组织多普勒成像(TDI)技术测量室间隔、侧壁等的舒张、收缩速度,评价美托洛尔对左室舒张功能的影响。方法原发性高血压(EH)左室肥厚患者23例,在服用美托洛尔2mg·kg-1·d-1前后,用TDI法分别测其二尖瓣环水平间隔、侧壁、前壁、下壁的收缩期峰值速度(Sm),舒张早期峰值速度(Em),舒张晚期峰值速度(Am),比较用药前后各部位Em/Am比值。结果服用美托洛尔3个月后,患者舒张功能均有明显改善。EH组左室各部位心肌Em增大,Am减少,Em/Am均明显提高。结论美托洛尔能够改善肥厚心肌的舒张功能,二尖瓣环水平的Em、Am的测定能克服二尖瓣血流的假性正常化,对用药后的变化也能够敏感地表现出来,可作为定量无创评价左室舒张功能的良好指标。     

超声心动图评价左心室舒张功能

左心室舒张功能（left ventricular diastolic funclion,LVDF）指左心室收缩后恢复到前一次舒张末期容量和压力的能力.近年来,左心室舒张功能不全受到越来越多的关注,舒张功能不全可单独存在,亦可与收缩功能障碍并存,且在多种疾病过程中常先于收缩功能障碍出现.据统计,在充血性心力衰竭（congestive heart failure,CHF）患者当中,约1/3主要为舒张性心衰,且研究发现舒张性心衰患者的预后要比收缩性心衰患者更差[1],因此,正确识别和评价左心室舒张功能不全具有重要的临床意义.     

多普勒组织成像评价择期与急诊血运重建对急性心肌梗死患者左心室收缩和舒张功能的影响

目的:应用二维超声心动图及多普勒组织成像(DTI)技术评价择期与急诊血运重建对急性心肌梗死(AMI)患者左心室收缩和舒张功能影响的差异.方法:根据AMI后不同的治疗方案,将54例首次AMI患者分为常规药物治疗组(常规组,n=18)、择期血运重建组(择期组,n=16,在常规药物治疗基础上接受择期冠状动脉支架置入术)和急诊血运重建组(急诊组,n=20,在常规药物治疗基础上接受静脉溶栓、急诊冠状动脉支架置入术).应用二维超声心动图检测患者AMI后1周、3个月、6个月及12个月的左心室射血分数、二尖瓣口血流舒张早期流速和心房收缩期流速比值;应用DTI检测二尖瓣环6个节段的收缩期运动速度峰值、舒张早期运动速度峰值和舒张晚期运动速度峰值的平均值.以20名健康体检者为正常对照组.结果:①左心室射血分数:与正常对照组比较,常规组、择期组、急诊组各时点均降低;与常规组同时点比较,择期组(3、6个月)、急诊组(6、12个月)时点均升高,差异均有统计学意义(P<0.05).②二尖瓣口血流舒张早期流速/心房收缩期流速:与正常对照组比较,常规组和急诊组各时点、择期组3、6、12个月均降低,差异均有统计学意义(P<0.05).③二尖瓣环收缩期运动速度峰值:与正常对照组比较,常规组、择期组、急诊组各时点均降低;急诊组6个月较常规组同时点升高,差异均有统计学意义(P<0.05).④二尖瓣环舒张早期运动速度峰值/舒张晚期运动速度峰值:与正常对照组比较,常规组和择期组各时点、急诊组(1周,6、12个月)均降低,差异均有统计学意义(P<0.05).⑤二尖瓣口血流舒张早期流速/二尖瓣环舒张早期运动速度峰值:与正常对照组比较,常规组各时点、择期组3、12个月及急诊组12个月均升高(P<0.05);择期组3个月和急诊组1周、3、6个月较常规组相应同时点降低,差异有统计学意义(P<0.05).结论:AMI后出现左心室收缩和舒张功能减退,急诊和择期血运重建均可改善患者左心室收缩功能,而择期血运重建对舒张功能的改善作用尚不明显;DTI可较二维超声心动图更敏感、准确地反映AMI后的左心室收缩和舒张功能变化.     

组织多普勒对高血压左心室舒张功能的评估

目的 探讨组织多普勒评价高血压患者左心室舒张功能方面的优越性.方法 将高血压患者分为无左室肥厚亚组(160例)和左室肥厚亚组(40例),选160例健康体检者为对照组,测定舒张早、晚期二尖瓣血流速度(E、A)峰值及左室侧壁二尖瓣环舒张早期运动速度(Em).结果 左室肥厚亚组Em、E/Em变化较无左室肥厚亚组差异有统计学意义[(7.7±2.6)cm/s比(9.9 ±2.8)cm/s;9.6 ±3.6比7.4±2.4,P＜0.05],而A、E/A则差异无统计学意义[(0.90 ±0.22)cm/s比(0.87 ±0.17)cm/s;0.80 ±0.34比0.88 ±0.28,P＞0.05].结论 组织多普勒指标Em、E/Em反映左室舒张功能的变化更敏感.

Abstract：

Objective To evaluate Left ventricular(LV) diastolic function in essential hypertension by conventional pulse-wave Doppler echocardiography (cPWD) and Doppler tissue imaging (DTI) and compare the two modalities. Methods Two hundred patients with essential hypertension were classified as NLVH subgroup (n = 160) and LVH subgroup (n =40) based on left ventricular mass index (LVMI) with one hundred and sixty health subjects as control group. The mitral valve flow pattern (MVFP) was obtained.Early diastolic (E) and late velocities (A) were measured and E/A was calculated. DTI was used to obtain the left ventricular lateral wall early diastolic mitral annulus velocity (Em) and E/Em was calculated.Results Essential hypertension patients had LV diastolic dysfunction both by cPWD (higher E and lower E/A ratio) and DTI (lower Em and higher E/Em ratio) compared with healthy subjects [E:(0. 88 ±0. 18)cm/s vs (0. 76 ±0. 19) cm/s;E/A ratio:0. 86 ±0. 28 vs 1.02 ±0. 38;Em: (9. 4 ±2. 8)cm/s vs (11. 9 ±3. 8)cm/s;E/Em ratio;7. 9 ± 2. 7 vs 6. 0 ± 1. 8: with all P value ＜0.01]. Em was significantly reduced and E/Em was significantly elevated in LVH subgroup than NLVH subgroup [Em; (7.7 ±2. 6) cm/s vs (9. 9 ± 2. 8) cm/s, E/Em: 9. 6 ± 3. 6 vs 7. 4 ± 2. 4, P ＜ 0. 05]. No significant difference was found in A and E/A between these two subgroups [(0. 90 ± 0. 22) cm/s vs (0. 87 ± 0. 17) cm/s; 0. 80 ± 0. 34 vs 0.88 ±0.28, P ＞ 0.05]. Conclusions cPWD and DTI both had implications to detect diastolic dysfunction in non-hypertrophic stage hypertension. Em、E/Em could be more sensitive and precise to reflect the impairment of diastolic function in the progress of hypertension.     

定量组织速度成像和核素心血池显像评价高血压患者右室功能的研究

目的探讨定量组织速度成像（QTVI）和核素心血池显像法评价高血压患者右心室收缩及舒张功能的应用价值。方法42例原发性高血压患者,在QTVI超声心动图检查结束后24 h内行核素心血池显像检查。QTVI测量右心室侧壁三尖瓣环处收缩期最大位移（DS）、收缩期峰值速度（Sm）、快速充盈期峰值速度（Em）、心房收缩期峰值速度（Am）,计算Em/Am值。^99mTc-RBC平衡法核素心血池显像测定右心室射血分数（RVEF）和右心室高峰充盈率（RPFR）。并对两种方法检测量值进行比较。结果高血压患者DS和Sm与RVEF显著正相关,分别为：r=0．61,P＜0．05; r=0．52,P＜0．05。Em及Em/Am值与RPFR亦具有显著相关性,分别为：r=0．48,P＜0．05; r=0．43,P＜0．05。结论与核素法比较,QTVI法Sm、DS、Em及Em/Am值能够较准确评价高血压患者右心室收缩及舒张功能。     

肥厚型心肌病左心室局部及整体舒张功能的研究

目的探讨肥厚型心肌病（HCM）患者左心室局部及整体舒张功能的变化。方法以40例肥厚型心肌病患者和40名健康人为研究对象,脉冲多普勒（PWD）测量二尖瓣口血流E峰、A峰,组织多普勒（TDI）测量二尖瓣环的前间隔、后间隔、前壁、下壁、后壁及侧壁6个位点的舒张早期峰值速度（Em）、舒张晚期峰值速度（Am）,计算E／A、Em／Am、E／Em,对各组参数之间的差异、Em与室壁厚度的相关性分别进行分析。结果HCM组二尖瓣瓣环各位点Em分别为前壁（0．053±0．019）m／s、后壁（0．055±0．016）m／s、前间隔（0．038±0．017）m／s、后间隔（0．049±0．015）m／s、侧壁（0．052±0．018）m／s、下壁（0．056±0．015）m／s;对照组二尖瓣环各位点Em分别为前壁（0．144-±0．031）m／s、后壁（0．139±0．033）m／s、前间隔（0．136±0．029）m／s、后间隔（0．143±0．028）m／s、侧壁（0．138±0．025）m／s、下壁（0．139±0．030）m／s,HCM组二尖瓣环各位点Em较对照组明显降低（P〈0．05）,但各位点间仅室壁增厚明显的前、后间隔瓣环位点与其他位点Em差异有统计学意义（P〈0．05）。HCM组E／Em为15．876±6．579,对照组E／Em为5．949-±1．283,二者比较差异有统计学意义（P〈0．05）。Em与心室壁厚度成线性负相关（r=-0．535,P〈0．05）,随着心室壁厚度增加而降低。结论HCM患者左心室局部及整体舒张功能明显降低,左室壁局部舒张功能降低与室壁厚度相关。     

组织多普勒联合Tei指数评价右室梗死患者右心功能

目的探讨应用多普勒组织成像(DTI)技术及Tei指数评价右室梗死患者的右心功能。方法急性下壁心肌梗死51例,于心尖四腔观切面以DTI速度模式录取三尖瓣游离壁侧瓣环、室间隔侧瓣环和游离壁中段收缩期、舒张早、晚期峰值运动速度(Sm、Em、Am)及Em/Am;以脉冲多普勒记录三尖瓣关闭至再次开放间期,并于胸骨旁短轴切面记录射血时间,计算右心Tei指数。结果右室心肌梗死组于三尖瓣游离壁侧瓣环及右室游离壁中部Sm、Em较无右室心肌梗死及正常对照组明显减低[游离壁侧瓣环Sm(70±20)cm/s比(87±19)cm/s和(106±21)cm/s,P<001;游离壁侧瓣环Em(63±19)cm/s比(79±18)cm/s和(96±19)cm/s;P<001;游离壁中段Sm(64±19)cm/s比(80±19)cm/s和(94±20)cm/s,P<005;游离壁中段Em(61±20)cm/s比(76±20)cm/s和(92±23)cm/s;P<005];右心Tei指数亦较其他两组普遍增高(065±019比040±015和026±010;P<001)。结论DTI技术检测三尖瓣游离壁侧瓣环及右室游离壁中段运动速度及右心Tei指数可无创、迅速评价右室心肌梗死患者右心室功能。     

应用速度向量成像及定量组织速度成像技术评价左心室舒张功能

目的 以左心室舒张末压(LVEDP)为标准,探讨速度向量成像(VVI)与定量组织速度成像(QTVI)技术各参数在评价左心室舒张功能中的应用价值.方法 51例接受心导管检查的患者纳入研究.介入诊疗前,使用超声心动图测量二尖瓣舒张早期血流速度(E峰)、舒张晚期血流速度(A峰)、E/A比值、左室射血分数;应用VVI及QTVI分别测算二尖瓣环舒张早期平均峰值运动速度(Em),计算E/Em值.介入术中,使用猪尾导管测量LVEDP.结果 VVI及QTVI测算的E/Em均与LVEDP旱良好的线性相关,相关系数分别为:r=0.808,P<0.01及r=0.692,P<0.01;两相关系数比较,前者高于后者(Z=2.246,P=0.025).VVI及QTVI测算的Em均与LVEDP呈良好的负相关,相关系数分别为:r=-0.740,P<0.01及r=-0.567,P<0.01;两相关系数比较,前者高于后者(Z=2.595,P=0.009).常规二维超声心动图测定的E/A值和LVEDP相关性差(r=0.117,P=0.415).结论 VVI作为一种新的超卢诊断新技术,在评价左心室舒张功能上优越于QTVI.E/Em及Em均可用于评价左心室舒张功能,前者与LVEDP相关性较高,但二者差异尚无统计学意义(P>0.05).     

组织多普勒对高血压左心室舒张功能的评估

Objective To evaluate Left ventricular(LV) diastolic function in essential hypertension by conventional pulse-wave Doppler echocardiography (cPWD) and Doppler tissue imaging (DTI) and compare the two modalities. Methods Two hundred patients with essential hypertension were classified as NLVH subgroup (n = 160) and LVH subgroup (n =40) based on left ventricular mass index (LVMI) with one hundred and sixty health subjects as control group. The mitral valve flow pattern (MVFP) was obtained.Early diastolic (E) and late velocities (A) were measured and E/A was calculated. DTI was used to obtain the left ventricular lateral wall early diastolic mitral annulus velocity (Em) and E/Em was calculated.Results Essential hypertension patients had LV diastolic dysfunction both by cPWD (higher E and lower E/A ratio) and DTI (lower Em and higher E/Em ratio) compared with healthy subjects [E:(0. 88 ±0. 18)cm/s vs (0. 76 ±0. 19) cm/s;E/A ratio:0. 86 ±0. 28 vs 1.02 ±0. 38;Em: (9. 4 ±2. 8)cm/s vs (11. 9 ±3. 8)cm/s;E/Em ratio;7. 9 ± 2. 7 vs 6. 0 ± 1. 8: with all P value ＜0.01]. Em was significantly reduced and E/Em was significantly elevated in LVH subgroup than NLVH subgroup [Em; (7.7 ±2. 6) cm/s vs (9. 9 ± 2. 8) cm/s, E/Em: 9. 6 ± 3. 6 vs 7. 4 ± 2. 4, P ＜ 0. 05]. No significant difference was found in A and E/A between these two subgroups [(0. 90 ± 0. 22) cm/s vs (0. 87 ± 0. 17) cm/s; 0. 80 ± 0. 34 vs 0.88 ±0.28, P ＞ 0.05]. Conclusions cPWD and DTI both had implications to detect diastolic dysfunction in non-hypertrophic stage hypertension. Em、E/Em could be more sensitive and precise to reflect the impairment of diastolic function in the progress of hypertension.     

用多普勒组织成像评价冠状动脉狭窄患者右室舒张功能

目的 :应用多普勒组织成像 （DTI）技术评价冠状动脉狭窄患者右室整体舒张功能的变化。方法 :测定三尖瓣环的运动速度及各舒张功能参数。结果 :单纯左冠状动脉狭窄组右室舒张功能均减低 ,混合支冠状动脉狭窄组右室舒张功能较单纯左支冠脉狭窄组进一步减低。结论 :DTI评估冠状动脉狭窄患者的右室舒张功能有一定的临床应用价值     

组织多普勒对高血压左心室舒张功能的评估

Objective To evaluate Left ventricular(LV) diastolic function in essential hypertension by conventional pulse-wave Doppler echocardiography (cPWD) and Doppler tissue imaging (DTI) and compare the two modalities. Methods Two hundred patients with essential hypertension were classified as NLVH subgroup (n = 160) and LVH subgroup (n =40) based on left ventricular mass index (LVMI) with one hundred and sixty health subjects as control group. The mitral valve flow pattern (MVFP) was obtained.Early diastolic (E) and late velocities (A) were measured and E/A was calculated. DTI was used to obtain the left ventricular lateral wall early diastolic mitral annulus velocity (Em) and E/Em was calculated.Results Essential hypertension patients had LV diastolic dysfunction both by cPWD (higher E and lower E/A ratio) and DTI (lower Em and higher E/Em ratio) compared with healthy subjects [E:(0. 88 ±0. 18)cm/s vs (0. 76 ±0. 19) cm/s;E/A ratio:0. 86 ±0. 28 vs 1.02 ±0. 38;Em: (9. 4 ±2. 8)cm/s vs (11. 9 ±3. 8)cm/s;E/Em ratio;7. 9 ± 2. 7 vs 6. 0 ± 1. 8: with all P value ＜0.01]. Em was significantly reduced and E/Em was significantly elevated in LVH subgroup than NLVH subgroup [Em; (7.7 ±2. 6) cm/s vs (9. 9 ± 2. 8) cm/s, E/Em: 9. 6 ± 3. 6 vs 7. 4 ± 2. 4, P ＜ 0. 05]. No significant difference was found in A and E/A between these two subgroups [(0. 90 ± 0. 22) cm/s vs (0. 87 ± 0. 17) cm/s; 0. 80 ± 0. 34 vs 0.88 ±0.28, P ＞ 0.05]. Conclusions cPWD and DTI both had implications to detect diastolic dysfunction in non-hypertrophic stage hypertension. Em、E/Em could be more sensitive and precise to reflect the impairment of diastolic function in the progress of hypertension.     

组织多普勒对高血压左心室舒张功能的评估

Objective To evaluate Left ventricular(LV) diastolic function in essential hypertension by conventional pulse-wave Doppler echocardiography (cPWD) and Doppler tissue imaging (DTI) and compare the two modalities. Methods Two hundred patients with essential hypertension were classified as NLVH subgroup (n = 160) and LVH subgroup (n =40) based on left ventricular mass index (LVMI) with one hundred and sixty health subjects as control group. The mitral valve flow pattern (MVFP) was obtained.Early diastolic (E) and late velocities (A) were measured and E/A was calculated. DTI was used to obtain the left ventricular lateral wall early diastolic mitral annulus velocity (Em) and E/Em was calculated.Results Essential hypertension patients had LV diastolic dysfunction both by cPWD (higher E and lower E/A ratio) and DTI (lower Em and higher E/Em ratio) compared with healthy subjects [E:(0. 88 ±0. 18)cm/s vs (0. 76 ±0. 19) cm/s;E/A ratio:0. 86 ±0. 28 vs 1.02 ±0. 38;Em: (9. 4 ±2. 8)cm/s vs (11. 9 ±3. 8)cm/s;E/Em ratio;7. 9 ± 2. 7 vs 6. 0 ± 1. 8: with all P value ＜0.01]. Em was significantly reduced and E/Em was significantly elevated in LVH subgroup than NLVH subgroup [Em; (7.7 ±2. 6) cm/s vs (9. 9 ± 2. 8) cm/s, E/Em: 9. 6 ± 3. 6 vs 7. 4 ± 2. 4, P ＜ 0. 05]. No significant difference was found in A and E/A between these two subgroups [(0. 90 ± 0. 22) cm/s vs (0. 87 ± 0. 17) cm/s; 0. 80 ± 0. 34 vs 0.88 ±0.28, P ＞ 0.05]. Conclusions cPWD and DTI both had implications to detect diastolic dysfunction in non-hypertrophic stage hypertension. Em、E/Em could be more sensitive and precise to reflect the impairment of diastolic function in the progress of hypertension.