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1.
Kevin B Shelburne Michael R Torry Marcus G Pandy 《Journal of orthopaedic research》2006,24(10):1983-1990
The aim of this study was twofold: first, to determine which muscles and ligaments resist the adduction moment at the knee during normal walking; and second, to describe and explain the contributions of muscles, ligaments, and the ground reaction force to medial and lateral compartment loading. Muscle forces, ground reaction forces, and joint motions obtained from a dynamic optimization solution for normal walking were used as input to a three-dimensional model of the lower limb. A static equilibrium problem was solved at each instant of the gait cycle to determine tibiofemoral joint loading at the knee. Medial compartment loading was determined mainly by the orientation of the ground reaction force. Because this force vector passed medial to the knee, it applied an adduction moment about the joint during stance. In contrast, all of the force transmitted by the lateral compartment was due to muscle and ligament action. The muscles that contributed most to support and forward propulsion during normal walking (quadriceps and gastrocnemius) also contributed most to knee stability in the frontal plane. The knee ligaments, particularly those of the posterior lateral corner, provided stability to the knee at certain periods of the stance phase, when activity of the important stabilizing muscles was low. 相似文献
2.
Hyung J. Kim Justin W. Fernandez Massoud Akbarshahi Jonathan P. Walter Benjamin J. Fregly Marcus G. Pandy 《Journal of orthopaedic research》2009,27(10):1326-1331
Musculoskeletal modeling and optimization theory are often used to determine muscle forces in vivo. However, convincing quantitative evaluation of these predictions has been limited to date. The present study evaluated model predictions of knee muscle forces during walking using in vivo measurements of joint contact loading acquired from an instrumented implant. Joint motion, ground reaction force, and tibial contact force data were recorded simultaneously from a single subject walking at slow, normal, and fast speeds. The body was modeled as an 8‐segment, 21‐degree‐of‐freedom articulated linkage, actuated by 58 muscles. Joint moments obtained from inverse dynamics were decomposed into leg‐muscle forces by solving an optimization problem that minimized the sum of the squares of the muscle activations. The predicted knee muscle forces were input into a 3D knee implant contact model to calculate tibial contact forces. Calculated and measured tibial contact forces were in good agreement for all three walking speeds. The average RMS errors for the medial, lateral, and total contact forces over the entire gait cycle and across all trials were 140 ± 40 N, 115 ± 32 N, and 183 ± 45 N, respectively. Muscle coordination predicted by the model was also consistent with EMG measurements reported for normal walking. The combined experimental and modeling approach used in this study provides a quantitative framework for evaluating model predictions of muscle forces in human movement. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27:1326–1331, 2009 相似文献
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Nicholas H. Yang Hamid Nayeb‐Hashemi Paul K. Canavan Ashkan Vaziri 《Journal of orthopaedic research》2010,28(12):1539-1547
Subject‐specific three‐dimensional finite element models of the knee joint were created and used to study the effect of the frontal plane tibiofemoral angle on the stress and strain distribution in the knee cartilage during the stance phase of the gait cycle. Knee models of three subjects with different tibiofemoral angle and body weight were created based on magnetic resonance imaging of the knee. Loading and boundary conditions were determined from motion analysis and force platform data, in conjunction with the muscle‐force reduction method. During the stance phase of walking, all subjects exhibited a valgus–varus–valgus knee moment pattern with the maximum compressive load and varus knee moment occurring at approximately 25% of the stance phase of the gait cycle. Our results demonstrated that the subject with varus alignment had the largest stresses at the medial compartment of the knee compared to the subjects with normal alignment and valgus alignment, suggesting that this subject might be most susceptible to developing medial compartment osteoarthritis (OA). In addition, the magnitude of stress and strain on the lateral cartilage of the subject with valgus alignment were found to be larger compared to subjects with normal alignment and varus alignment, suggesting that this subject might be most susceptible to developing lateral compartment knee OA. © 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:1539–1547, 2010 相似文献
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Modulating tibiofemoral contact force in the sheep hind limb via treadmill walking: Predictions from an opensim musculoskeletal model 下载免费PDF全文
Zachary F. Lerner Benjamin C. Gadomski Allison K. Ipson Kevin K. Haussler Christian M. Puttlitz Raymond C. Browning 《Journal of orthopaedic research》2015,33(8):1128-1133
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Dong Zhao Scott A Banks Kim H Mitchell Darryl D D'Lima Clifford W Colwell Benjamin J Fregly 《Journal of orthopaedic research》2007,25(6):789-797
The external knee adduction torque has been proposed as a surrogate measure for medial compartment load during gait. However, a direct link between these two quantities has not been demonstrated using in vivo measurement of medial compartment load. This study uses in vivo data collected from a single subject with an instrumented knee implant to evaluate this link. The subject performed five different overground gait motions (normal, fast, slow, wide, and toe-out) with simultaneous collection of instrumented implant, video motion, and ground reaction data. For each trial, the knee adduction torque was measured externally while the total axial force applied to the tibial insert was measured internally. Based on data collected from the same subject performing treadmill gait under fluoroscopic motion analysis, a regression equation was developed to calculate medial contact force from the implant load cell measurements. Correlation analyses were performed for the stance phase and entire gait cycle to quantify the relationship between the knee adduction torque and both the medial contact force and the medial to total contact force ratio. When the entire gait cycle was analyzed, R(2) for medial contact force was 0.77 when all gait trials were analyzed together and between 0.69 and 0.93 when each gait trial was analyzed separately (p < 0.001 in all cases). For medial to total force ratio, R(2) was 0.69 for all trials together and between 0.54 and 0.90 for each trial separately (p < 0.001 in all cases). When only the stance phase was analyzed, R(2) values were slightly lower. These results support the hypothesis that the knee adduction torque is highly correlated with medial compartment contact force and medial to total force ratio during gait. 相似文献
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《Journal of orthopaedic research》2017,35(10):2251-2259
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The objective of this study was to measure the effect of kneeling on tibiofemoral contact following cruciate-retaining and posterior-stabilized total knee arthroplasty. Five cadaveric knees were tested on a custom testing system that allowed physiologic muscle loading. Three forces were used to simulate nonkneeling, double-stance kneeling, and single-stance kneeling at flexion angles of 90°, 105°, 120°, and 135°. Tibiofemoral contact areas and pressures were measured using the Tekscan (South Boston, MA) system. Kneeling increased contact areas and pressures in both designs with variable significance (P < .05). Moving from double- to single-stance kneeling increased pressures in the cruciate-retaining group but decreased pressures in the posterior-stabilized group (P < .05). Chronic, repetitive kneeling after total knee arthroplasty may increase polyethylene wear due to increased contact areas and pressures. 相似文献
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Adam Trepczynski Ines Kutzner Evgenios Kornaropoulos William R. Taylor Georg N. Duda Georg Bergmann Markus O. Heller 《Journal of orthopaedic research》2012,30(3):408-415
The patellofemoral (PF) joint plays an essential role in knee function, but little is known about the in vivo loading conditions at the joint. We hypothesized that the forces at the PF joint exceed the tibiofemoral (TF) forces during activities with high knee flexion. Motion analysis was performed in two patients with telemetric knee implants during walking, stair climbing, sit‐to‐stand, and squat. TF and PF forces were calculated using a musculoskeletal model, which was validated against the simultaneously measured in vivo TF forces, with mean errors of 10% and 21% for the two subjects. The in vivo peak TF forces of 2.9–3.4 bodyweight (BW) varied little across activities, while the peak PF forces showed significant variability, ranging from less than 1 BW during walking to more than 3 BW during high flexion activities, exceeding the TF forces. Together with previous in vivo measurements at the hip and knee, the PF forces determined here provide evidence that peak forces across these joints reach values of around 3 BW during high flexion activities, also suggesting that the in vivo loading conditions at the knee can only be fully understood if the forces at the TF and the PF joints are considered together. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:408–415, 2012 相似文献
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Effect of component mal‐rotation on knee loading in total knee arthroplasty using multi‐body dynamics modeling under a simulated walking gait 下载免费PDF全文
Zhenxian Chen Ling Wang Yaxiong Liu Jiankang He Qin Lian Dichen Li Zhongmin Jin 《Journal of orthopaedic research》2015,33(9):1287-1296
Mal‐rotation of the components in total knee arthorplasty (TKA) is a major cause of postoperative complications, with an increased propensity for implant loosening or wear leading to revision. A musculoskeletal multi‐body dynamics model was used to perform a parametric study of the effects of the rotational mal‐alignments in TKA on the knee loading under a simulated walking gait. The knee contact forces were found to be more sensitive to variations in the varus–valgus rotation of both the tibial and the femoral components and the internal–external rotation of the femoral component in TKA. The varus–valgus mal‐rotation of the tibial or femoral component and the internal–external mal‐rotation of the femoral component with a 5° variation were found to affect the peak medial contact force by 17.8–53.1%, the peak lateral contact force by 35.0–88.4% and the peak total contact force by 5.2–18.7%. Our findings support the clinical observations that a greater than 3° internal mal‐rotation of the femoral component may lead to unsatisfactory pain levels and a greater than 3° varus mal‐rotation of the tibial component may lead to medial bone collapse. These findings determined the quantitative effects of the mal‐rotation of the components in TKA on the contact load. The effect of such mal‐rotation of the components of TKA on the kinematics would be further addressed in future studies. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1287–1296, 2015. 相似文献
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Roda RD Wilson JL Wilson DA Richardson G Dunbar MJ 《The Journal of arthroplasty》2012,27(6):1244-1250
Computer-assisted surgery can be used to measure 3-dimensional knee function during arthroplasty surgery; however, it is unknown if the movement of the knee measured during surgery is related to the in vitro, dynamic state of the knee joint, specifically the knee adduction moment during gait, which has been related to implant migration. The purpose of this study was to determine if the preoperative adduction moment is correlated with the knee abduction/adduction angle measured intraoperatively. A statistically significant correlation was found between the mean (r(2) = 0.59; P = .001) and peak (r(2) = 0.53; P = .003) preoperative knee adduction moment and the mean abduction/adduction angle measured intraoperatively. The association found in this study suggests the potential for incorporating functional information that relates to surgical outcome into surgical decision making using computer-assisted surgery. 相似文献
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BackgroundThe knee adduction moment (KAM) is considered an index for estimating the knee mechanical load, and increased KAM peak and KAM impulse are related to increased medial knee load and progression of knee joint degeneration. We aimed to verify the biomechanical factors of gait related to medial knee loading in patients 6 months after TKA.MethodsThirty-nine women who underwent TKA were enrolled. A three-dimensional gait analysis was performed 6 months postoperatively to generate data on the lower limb joint angle, moment, and power at the backward component (braking phase) and forward component (propulsion phase) peaks of the ground reaction force. Medial knee loading was evaluated using the time-integrated value of KAM during the stance period (KAM impulse). The higher the value of the KAM impulse, the higher the medial knee joint load. The relationships between the KAM impulse and the data for biomechanical factors were evaluated using partial correlation analysis with gait speed as a control factor.ResultsIn the braking phase, the KAM impulse positively correlated with the knee adduction angle (r = 0.377) and negatively correlated with the toe-out angle (r = −0.355). The KAM impulse positively correlated with the knee adduction angle (r = 0.402), the hip flexion moment (r = 0.335), and the hip adduction moment (r = 0.565) and negatively correlated with the toe-out angle (r = −0.357) in the propulsive phase.ConclusionThe KAM impulse 6 months after TKA was related to the knee adduction angle, hip flexion moment, hip adduction moment, and toe-out angle. These findings may provide fundamental data for controlling variable medial knee joint load after TKA and implementing patient management strategies to ensure implant durability. 相似文献
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General scheme to reduce the knee adduction moment by modifying a combination of gait variables 下载免费PDF全文
Julien Favre Jennifer C. Erhart‐Hledik Eric F. Chehab Thomas P. Andriacchi 《Journal of orthopaedic research》2016,34(9):1547-1556
Reducing the knee adduction moment (KAM) is a promising treatment for medial compartment knee osteoarthritis (OA). Although several gait modifications to lower the KAM have been identified, the potential to combine modifications and individual dose‐responses remain unknown. This study hypothesized that: (i) there is a general scheme consisting of modifications in trunk sway, step width, walking speed, and foot progression angle that reduces the KAM; (ii) gait modifications can be combined; and (iii) dose‐responses differ among individuals. Walking trials with simultaneous modifications in step width, walking speed, progression angle, and trunk sway were analyzed for 10 healthy subjects. Wider step width, slower speed, toeing‐in, and increased trunk sway resulted in reduced first KAM peak, whereas wider step width, faster speed, and increased trunk sway reduced the KAM angular impulse. Individual regressions accurately modeled the amplitude of the KAM variables relative to the amplitude of the gait modification variables, while the dose‐responses varied strongly among participants. In conclusion, increasing trunk sway, increasing step width, and toeing‐in are three gait modifications that could be combined to reduce KAM variables related to knee OA. Results also indicated that some gait modifications reducing the KAM induced changes in the knee flexion moment possibly indicative of an increase in knee loading. Taken together with the different dose‐responses among subjects, this study suggested that gait retraining programs should consider this general scheme of modifications with individualization of the modification amplitudes. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1547–1556, 2016. 相似文献
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Sharma A Komistek RD Ranawat CS Dennis DA Mahfouz MR 《The Journal of arthroplasty》2007,22(3):404-416
This study compared the in vivo femoropolyethylene contact pressures generated in fixed-bearing total knee arthroplasty (TKAs) with those in mobile-bearing TKAs. In vivo kinematics obtained from a 2-dimensional to 3-dimensional registration technique and soft tissue locations derived from computed tomographic scans were entered into a 3-dimensional inverse dynamics mathematical model to determine the in vivo bearing contact forces. The contact areas were obtained from the assembly of computer-aided design models of the components. The contact pressure was defined as the ratio of the contact forces to the contact areas. The results indicate that the in vivo contact pressures in each TKA are greater for the medial condyle than for the lateral condyle. The ability of the mobile-bearing TKA to rotate maintains higher femoropolyethylene contact, resulting in lesser contact pressures, as compared with the fixed-bearing TKA. 相似文献
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John A. Szivek PhD Philip L. Anderson MS James B. Benjamin MD 《The Journal of arthroplasty》1996,11(8):952-963
Seven total knee arthroplasty systems were tested to determine contact stress patterns and contact areas using a calibrated Fuji film stress analysis technique. Knees were loaded to 2,000 N (204 kg) at 15°, 60°, 90°, and 135° flexion at 24 and 37°C. Evaluation of stresses at 37°C at 15° and 60° using an average contact stress assessment technique indicated that the LCS meniscal bearing knee system, (DePuy, Warsaw, IN), the AMK knee with a constrained insert (DePuy), and the PFC knee with a posterior-lipped insert (Johnson and Johnson, Raynham, MA) had the lowest average contact stresses (near or below 10 MPa). The PFC with a regular insert (Johnson and Johnson), the Ortholoc II (Dow Corning Wright, Arlington, TN), and the AMK with a regular insert (DePuy) had intermediate contact stresses. The AMK with a Hylamer-M insert (DePuy) and the MG II (Zimmer, Warsaw, IN) had the highest average contact stresses (near or above 20 MPa). A stress-calibrated Fuji film measurement technique has shown that an assessment of ranges of contact stress provides much more information about regions of expected wear than an assessment of average contact stresses. Testing of the tibiofemoral articulation of artificial knees revealed that all knees had some areas of contact with maximum stresses in excess of 15 MPa. As the yield strength of ultrahigh-molecular-weight polyethylene is approximately 15 MPa, all tibial inserts could wear to some extent. Peak contact stresses at four test angles of the AMK, Series 7000 (Osteonics, Allendale, NJ:) Genesis (Smith & Nephew Orthopaedics, Memphis, TN), and MG II patellofemoral articulations were high (above 30 MPa). Contact areas varied from line-shaped to bilateral circular or elliptical shapes. The LCS knee system experienced substantially lower patellofemoral contact stresses and larger contact areas. Changes in conformity of knee designs are warranted to overcome wear problems. Peak contact stresses measured from the LCS meniscal bearing tibiofemoral and patellofemoral joint were in excess of 30 MPa in some areas at low flexion angles. This design does create large areas of contact at very low contact pressures, however, and for this reason is expected to wear less than other designs. 相似文献
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Evidence and mechanism by which upper partial fibulectomy improves knee biomechanics and decreases knee pain of osteoarthritis 下载免费PDF全文
Yong Nie ZeYu Huang Bin Xu Bin Shen Virginia B. Kraus FuXing Pei 《Journal of orthopaedic research》2018,36(8):2099-2108
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《Journal of orthopaedic research》2017,35(6):1283-1289
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Grand challenge competition to predict in vivo knee loads 总被引:2,自引:0,他引:2
Fregly BJ Besier TF Lloyd DG Delp SL Banks SA Pandy MG D'Lima DD 《Journal of orthopaedic research》2012,30(4):503-513
Impairment of the human neuromusculoskeletal system can lead to significant mobility limitations and decreased quality of life. Computational models that accurately represent the musculoskeletal systems of individual patients could be used to explore different treatment options and optimize clinical outcome. The most significant barrier to model-based treatment design is validation of model-based estimates of in vivo contact and muscle forces. This paper introduces an annual "Grand Challenge Competition to Predict In Vivo Knee Loads" based on a series of comprehensive publicly available in vivo data sets for evaluating musculoskeletal model predictions of contact and muscle forces in the knee. The data sets come from patients implanted with force-measuring tibial prostheses. Following a historical review of musculoskeletal modeling methods used for estimating knee muscle and contact forces, we describe the first two data sets used for the first two competitions and summarize four subsequent data sets to be used for future competitions. These data sets include tibial contact force, video motion, ground reaction, muscle EMG, muscle strength, static and dynamic imaging, and implant geometry data. Competition participants create musculoskeletal models to predict tibial contact forces without having access to the corresponding in vivo measurements. These blinded predictions provide an unbiased evaluation of the capabilities and limitations of musculoskeletal modeling methods. The paper concludes with a discussion of how these unique data sets can be used by the musculoskeletal modeling research community to improve the estimation of in vivo muscle and contact forces and ultimately to help make musculoskeletal models clinically useful. 相似文献
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Effects of lateral‐offset sole shoes on knee adduction moment in women with medial compartment knee osteoarthritis 下载免费PDF全文
Woo Young Jang Hae Woon Jung Gi Won Choi Hyun Min Lee Hae Soo Park Soon Hyuck Lee 《Journal of orthopaedic research》2018,36(6):1694-1700
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Xavier Robert-Lachaine Yoann Dessery Étienne L. Belzile Sylvie Turmel Philippe Corbeil 《Journal of orthopaedic research》2020,38(10):2262-2271
Immediate biomechanical and functional effects of knee braces are often reported, however, the duration and type of knee brace treatment for knee osteoarthritis (KOA) remain unclear. The objective was to evaluate usage, comfort, pain, and knee adduction moment (KAM) of three knee braces each worn 3 months by patients. Twenty-four patients with KOA were assigned in a randomized crossover trial a valgus three-point bending system brace (V3P-brace), an unloader brace with valgus and external rotation functions (VER-brace) and a stabilizing brace used after ligament injuries (ACL-brace). Functional questionnaires and gait assessment were carried out before and after each brace wear period of 3 months. A Friedman test was applied between brace wear diary recordings. Repeated measures analyses of variance contrasted the factors brace type (ACL, V3P, and VER), time (pre and post) and wear (without and with) on comfort, pain, function, and KAM. Brace usage was similar, but the V3P-brace was slightly less worn. Discomfort was significantly lowered with the VER-brace. All knee braces relieved pain and symptoms from 10% to 40%. KAM angular impulse was reduced with the three braces, but the VER-brace obtained the lowest relative reduction of 9%. The interaction between time and wear indicated that part of the KAM reduction with brace wear was maintained post treatment. All three knee braces have great benefits for pain and function among the medial KOA population. The VER-brace offers additional advantages on daily use, comfort and KAM, which could improve compliance to brace treatment. 相似文献