4424例妇科病普查与生殖健康状况分析

目的:了解海口市龙华区妇女生殖健康状况,制定有效的防治措施,促进生殖健康。方法:对海口市龙华区2009～2012年4424例已婚妇女进行妇科病普查。普查结果进行流行病学及统计学分析。结果:应检人数5000例,实检人数4424例,占88.5%。普查率患病人数2686例,患病率为60.7%。妇科疾病以生殖道感染为首位,乳腺疾病主要以乳腺增生为主占第二位。结论:育龄期妇女疾病患病率高,通过普查普治,增强生殖健康保健意识,建立正确的健康生活行为。     

襄阳市已婚妇女生殖健康情况分析

目的:通过对襄阳市已婚妇女进行生殖健康普查,了解我市已婚妇女生殖健康状况,针对性进行综合干预,以降低妇女生殖系统疾病的发生。方法:对我院2015年接受普查的8 832例妇女患病情况进行回顾性统计分析。结果:乳腺疾病患病率为65.96%,妇科疾病患病率为57.23%,妇女疾病前三位依次为乳腺疾病、阴道炎、宫颈炎;检出乳腺癌2例,宫颈癌5例,宫颈癌前病变21例。结论:妇女常见病患病率较高,癌前病变检出率较高,定期进行妇女病普查是促进妇女健康的重要措施,做到早发现、早诊断、早治疗;在积极开展妇女病普查治疗同时,应加强健康教育,促进全社会妇女增强自我保健、防范疾病意识,提高妇女的健康水平和生存质量。     

宁河县妇科疾病普查结果分析

目的:了解和掌握天津市宁河县辖区已婚妇女妇科疾病患病情况,为今后社区开展妇女病防治提供依据,更好地做好育龄妇女生殖健康工作。方法:对29 292例妇女免费妇女病普查结果进行分析。结果:查出妇科疾病18 914例,患病率为64.57%;乳腺疾病4 944例,患病率为16.92%。患病率居前三位疾病依次是:宫颈炎9 308例,患病率为31.78%;乳腺增生4 191例,患病率为14.34%;阴道炎3 935例,患病率为13.43%。结论:生殖系统和乳腺疾病目前仍是影响妇女健康的主要疾病。妇女病普查对早发现早诊断早治疗妇科疾病有重要意义。只有定期开展妇女病普查、加强科普宣教、卫生保健知识宣传才能不断提高妇女疾病的防治水平,进而提高妇女的健康水平。     

4970例已婚妇女妇科疾病普查结果分析

目的通过普查资料统计分析,了解本镇妇女生殖健康状况及妇科疾病患病情况,以便制定有效的防治措施,改善妇女的生活质量.方法2010年5月~6月,由集仕港中心卫生院妇产科医护人员及相关辅助科室医生,对该镇4970例已婚育龄妇女进行妇女病常规普查及相关实验室检查.结果在普查人数中,患一种或一种以上妇科疾病人数3441例,患病率69.24%,前3位疾病依次为宫颈疾病、阴道炎、乳腺疾病.结论已婚妇女妇科常见疾病患病率较高,以生殖系统感染为主.通过妇女病普查,大多数妇科疾病都能得到早发现、早诊断、早治疗.积极开展健康教育及卫生宣传,普查结合普治,控制患病率,提高已婚妇女的自我保健意识和生殖健康水平     

1335例妇女病普查情况分析与干预措施

目的 了解我钦南区妇科疾病患病情况,采取干预措施,提高妇女生殖健康水平.方法 对2006年8～10月妇科病普查情况进行回顾性分析.结果 妇女病患病率为72.13%,慢性宫颈炎患病率47.94%,乳腺疾病患病率32.13%,阴道炎患病率 16.78%,子宫肌瘤4.64%,盆腔炎3.82%,卵巢囊肿占1.57%.结论 妇女病普查是对妇科常见疾病的早发现、早诊断、早治疗,是提高妇女生殖健康水平的有效措施之一.     

近红外线扫描检测海口市妇女乳腺疾病的研究

目的 :了解海口市妇女乳腺疾病患病情况 ,制定防治措施。方法 :对海口市部分企事业单位整群抽样 ,对737例妇女用电脑近红外线扫描仪进行乳腺检测。结果 :妇女乳腺疾病患病率为 46 .6 8% ,乳腺癌的患病率为 0 .14 %。结论 :妇女应定期进行乳腺疾病的检查     

1624例妇女乳腺疾病普查结果分析

目的为了解高台县已婚妇女乳腺疾病的发病情况,对高台县的已婚妇女进行了乳腺疾病普查.方法采用美国通用公司制造的GEVoluson730prov四维彩超结合物理查体.结果查出乳腺疾病947例,总患病率58.31%,.其中乳腺增生检出率最高,占各类乳腺疾病的77.72%,其他依次是乳腺纤维瘤占17.32%,乳腺囊肿占4.22%.各年龄段乳腺疾病发病率不同,30—岁年龄组最高,占患病人数的42.98%,40—岁年龄组次之,占患病率37.70%.结论积极开展妇女乳腺疾病的普查,做到早发现、早诊断、早治疗,对乳腺疾病的预防有着极其重要意义.     

大兴区礼贤镇2006～2010年妇女病普查结果分析

目的为了解大兴区礼贤镇农村妇女生殖健康状况,以便针对性制定妇女病防治措施。方法对2006～2010年8682例已婚妇女普查情况进行体检的结果分析。结果 5年间共计妇女病普查人数为8682例,其中患病人数4744例,平均患病率为54.64%,包括宫颈炎,宫颈糜烂、宫颈上皮内瘤样病变、乳腺疾病、子宫肌瘤、阴道炎、卵巢囊肿。结论加强宣教,增强认识,提高妇女病普查率;采取各种干预措施降低妇女病患病率,进一步提高大兴区礼贤镇适龄妇女的生活质量和健康水平。     

2011年我院6504例已婚妇女妇科疾病普查结果分析

目的 了解2011年来我院体检的已婚妇女的妇科疾病的发展情况及趋势,为妇科疾病的防治提供依据.方法 对2011来我院体检的6504例厂矿企业单位,机关,事业单位的已婚妇女进行妇女病普查,根据普查结果分析常见病所占的比例和发展趋势.结果 共查出妇科疾病4032例(患病率62％).其中机关,事业单位2275例(患病率60.5％),厂矿企业单位1757例(患病率64％).妇科病前三位疾病为:乳腺疾病、宫颈炎、阴道炎.机关,事业单位乳腺疾病患病率高于厂矿企业单位,厂矿企业单位妇女的宫颈炎、阴道炎患病率高于机关、事业单位.结论 妇女病普查普治是妇女保健工作的重要内容,应加强妇女保健卫生宣传工作,使妇女了解生殖健康的重要性,提高自我保健意识,有效降低妇女病发生率.积极定期进行妇女病普查,做到早发现,早诊断,早治疗,提高妇女健康水平.     

6132例中小学女职工妇女病普查结果分析

目的了解柳州市柳南区鱼峰区中小学女职工常见病、多发病患病率,为有效控制妇女病的发生,制定干预措施,提高妇女健康水平。方法对2006年1月～2007年12月柳州市柳南区鱼峰区中小学女职工6132例进行妇科病、乳腺病普查。结果6132例中患各种妇科病及乳腺病者共3557例,患病率为58%,妇科病1737例,占总检人数28.33%,妇科疾病前三位分别宫颈炎、阴道炎、子宫肌瘤,6132例中患乳腺疾病1820例,占总检人数29.68%,乳腺疾病以乳腺增生为主。结论定期普查,采用多学科协作群防群治是提高妇女健康水平的有效途径。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.