Does Threshold Nighttime Electrical Stimulation Benefit Children With Spina Bifida?: A Pilot Study

Background  

Electrical stimulation is an established treatment for muscle weakness. However, traditional tectonic stimulation is poorly tolerated in children as a result of discomfort. Threshold electrical stimulation performed at night reportedly increases muscle strength in a variety of neuromuscular conditions and has been well tolerated in children.     

How Does TKA Kinematics Vary With Transverse Plane Alignment Changes in a Contemporary Implant?

Background  

Assessment of patient function after TKA often focuses on implant alignment and daily activity capabilities, but the functional results and kinematics of the TKA are not easily predicted by some of these parameters during surgery.     

Does the Age of Donor Kidneys Affect Nocturnal Polyuria in Patients With Successful Real Transplantation?

Background

We investigated whether the age of donor kidneys influences the incidence of nocturnal polyuria in patients with successful renal transplantation (RTX).

Total Joint Arthroplasty in Patients With Schizophrenia: How Much Does It Increase the Risk of Complications?

Background

Mental illness is an often overlooked comorbidity in the total joint arthroplasty (TJA) population. The purpose of this study was to evaluate the risk of schizophrenia on the outcomes of TJA.

Does Age or Bilateral Disease Influence the Value of Hip Arthroplasty?

Background  

Measuring value in medicine is an increasingly important issue as healthcare spending continues to rise and cost containment becomes even more important. However, value assessments can be affected by patient factors and comorbidities.     

How Does Cholecystectomy Influence Recurrence of Idiopathic Acute Pancreatitis?

Background

Idiopathic acute pancreatitis is diagnosed in approximately 10–30 % of cases of acute pancreatitis. While there is evidence to suggest that the cause in many of these patients is microlithiasis, this fact has not been translated into a resource efficient treatment strategy that is proven to reduce recurrence rates. The aim of this study was to examine the value of prophylactic cholecystectomy following an episode of acute pancreatitis in patients with no history of alcohol abuse and no stones found on ultrasound.

Methods

This was a retrospective study of 2236 patients who presented to a regional Australian hospital. Patients were included when diagnosed with acute pancreatitis with no confirmed cause. Recurrence of acute pancreatitis was compared between those that did and did not undergo cholecystectomy.

Results

One hundred ninety-five consecutive patients met the study definition of “idiopathic” acute pancreatitis. 33.8 % (66/195) underwent cholecystectomy. The patients who had cholecystectomy had a recurrence rate of 19.7 % (13/66) whereas, of those managed expectantly, 42.8 % (68/159) had at least one recurrence of acute pancreatitis (P?=?0.001).

Conclusions

Following an episode of acute pancreatitis with no identifiable cause, in patients fit for surgery, cholecystectomy should be considered to reduce the risk of recurrent episodes of pancreatitis.

     

Safety of Liver Resection in the Elderly: How Important Is Age?

Background

With the aging population, more elderly patients are being considered for hepatic resection. We investigated whether advanced age was associated with higher rate and severity of postoperative complications.

Methods

A total of 75 patients aged ≥70 years (group E) were matched with 75 patients aged <70 years (group Y) by the extent of liver resection and by operative indications. Primary outcome measures were rates and severity of complications. Secondary outcome measures were length of hospital stay and discharge destination. Univariate analysis was also performed to identify variables associated with higher surgical risk.

Results

Male-to-female ratio was 43:32 in both groups. Overall complication rates were 44 and 33.3% in group E and Y, respectively (P = 0.241; odds ratio = 1.57; 95% confidence interval [95% CI], 0.81–3.05). There was no mortality in both groups. The only postoperative age-related morbidity was confusion in the elderly. There was no difference in the rates of severe complications (grade ≥3) between group E and group Y (16 vs. 14.7%; P = 0.744; odds ratio = 1.11; 95% CI, 0.46–2.70). Median length of hospital stay were 7 and 6 days, respectively (P = 0.01). Nineteen percent and 1% of patients in group E and group Y were discharge to rehabilitation facilities, respectively (P = 0.001). Univariate analysis showed that preoperative systemic chemotherapy and longer operative time were associated with higher morbidity in the elderly.

Conclusions

Liver resection can be performed in patients aged ≥70 years as safely as in younger patients. Duration and timing of systemic chemotherapy before liver resection should be optimized to minimize postoperative morbidity.     

Participation and Life Satisfaction in Aged People with Spinal Cord Injury: Does Age at Onset Make a Difference?

Background:

Few studies have reported on outcomes in samples of elderly people with SCI and the impact of the age at onset of SCI is unclear.

Objective:

To study levels of participation and life satisfaction in individuals with SCI aged 65 years or older and to analyze differences in participation and life satisfaction scores between individuals injured before or after 50 years of age.

Methods:

This cross-sectional survey included 128 individuals with SCI who were at least 65 years old. Age at onset was dichotomized as <50 or ≥50 years of age. Participation was measured with the Frequency scale of the Utrecht Scale for Evaluation-Participation, and life satisfaction was measured with 5 items of the World Health Organization Quality of Life abbreviated form.

Results:

Participants who were injured before 50 years of age showed similar levels of functional status and numbers of secondary health conditions but higher participation and life satisfaction scores compared to participants injured at older age. In the multiple regression analysis of participation, lower current age, higher education, and having paraplegia were significant independent determinants of increased participation (explained variance, 25.7%). In the regression analysis of life satisfaction, lower age at onset and higher education were significant independent determinants of higher life satisfaction (explained variance, 15.3%).

Conclusion:

Lower age at onset was associated with better participation and life satisfaction. This study did not reveal indications for worsening participation or life satisfaction due to an accelerated aging effect in this sample of persons with SCI.Key words: aged, aging, quality of life, rehabilitation outcome, spinal cord injuriesAging in the population of individuals with spinal cord injury (SCI) has 2 aspects: the average age at onset of SCI is increasing and people with SCI live on average longer than half a century ago. Age at onset of traumatic SCI has risen from 28.7 years in the 1970s to 40 years in the United States during the 2005-2009 period.¹ In other countries, a bimodal distribution of age at onset of traumatic SCI has emerged in recent years.² In the Netherlands, the median age at first admission to the acute hospital after traumatic SCI has increased to 62 years in 2010.³ People who are older at injury are more often victims of falls and have nontraumatic, incomplete, and cervical SCI more often than individuals who are injured at a younger age.³-⁵ They are more vulnerable than younger people and are at greater risk of death shortly after the onset of SCI.⁶ If they survive the acute phase, they are less often referred to specialized rehabilitation hospitals.³ If referred to a specialized center, elderly people with SCI may gain a similar rate of functional improvement⁷; but because older patients generally have lower functional scores at admission, they also show worse rehabilitation outcomes compared to people who are injured at a younger age.^4,8–10The life expectancy of the population with SCI has grown over the last 50 to 60 years.¹¹ Many people with a new SCI can expect to live another 30 to 40 years or more. However, this life expectancy has not grown in recent decades and is still clearly below that of the general population.¹¹ People with SCI are at risk of “accelerated aging” due to an inactive lifestyle and a greater risk of obesity, chronic inflammation, pressure ulcers, and pulmonary infections.^1,12Participation and quality of life in aged persons with SCI are influenced by a complex interaction of many factors associated with current chronologic age, age at injury, duration of injury, and age cohort effects. It has been suggested that increasing age and being of older age at onset of SCI are independently associated with worse outcomes and that longer time after SCI is associated with better adjustment, whereas the impact of age cohort effects on adjustment is unknown.^1,13–15 However, research into the impact of these health-related changes on participation and life satisfaction of aged people living with SCI is sparse, and associations with aging are often studied in samples that are well below retirement age.¹⁵Only 2 longitudinal projects in aging people with SCI are available. Krause and Bozard¹⁶ described 35-year longitudinal data of 64 individuals with SCI (mean age, 61.5 years; mean time since SCI, 41.4 years). The participants rated their overall adjustment significantly higher at follow-up than they did at the first assessment 35 years before (8.4 and 7.6 on a 0–10 scale, respectively). The participants, however, showed decreases in satisfaction with social life and participation indicators (visits with others, outings).¹⁶ Charlifue and Gerhart¹⁷ found in a large sample of people with long-standing SCI (mean age, 59 years; time since onset of SCI, 36 years at follow-up) a small but significant decline in community reintegration over a period of 10 years. Life satisfaction, however, remained stable over this time period.¹⁷It is still unclear how people aging with SCI differ from people who acquire SCI in later life.¹⁸ Given the same age, the accelerated aging hypothesis predicts that people injured at a younger age will be worse off. However, the reverse – higher age at injury is an independent predictor of worse functional outcomes – has also been shown.¹⁰ We therefore used data from earlier research with the following objectives: (a) to describe the levels of participation and life satisfaction in individuals with SCI aged 65 years or older, and (b) to analyze differences in participation and life satisfaction between individuals injured before 50 years of age or at or after 50 years of age.     

Does Research Participation Make a Difference in Residency Training?

Background

The American Board of Orthopaedic Surgery requirements state that an orthopaedic residency must offer at least 5 years of clinical education and some exposure to research. To expose residents to basic research, some programs, including ours, have a research track that allows for 1 year of basic science research. The degree to which research productivity during residency—which may be something that can perhaps be influenced by interventions like research tracks during residency—affects residency graduates’ future research contributions is unknown.

Questions/purposes

Our research goals were to determine whether (1) residents who published in a peer-reviewed journal during residency were more likely to publish in their careers after graduation; (2) residents who participated in an elective research year were more likely to publish at least one paper in a peer-reviewed journal during residency; and (3) residents who participated in the research year were more likely to choose academic careers.

Methods

Using questionnaires, online PubMed searches, and office contact, the career paths (academic versus private practice) and publications in peer-reviewed journals of all 122 Case Western Reserve University orthopaedics residents who completed training from 1987 to 2006 were analyzed.

Results

Seventy-five percent of residents who published peer-reviewed research during residency continued with peer-reviewed publications in their careers versus 55% of residents who did not publish during residency (p = 0.02). No difference in career paths was observed between the Case Western Reserve University research and traditional track-trained surgeons. During residency, however, research track-trained surgeons were more likely to publish in peer-reviewed journals (71% versus 41% of traditional track-trained surgeons, p < 0.01).

Conclusions

Residents who publish in a peer-reviewed journal during residency are more likely to continue publishing in their future careers as orthopaedic surgeons. Future studies are needed to elucidate the causative factors in the association between publishing in a peer-reviewed journal during training and further contributions later in an orthopaedic surgeon’s career.     

Hepatectomy in Elderly Patients: Does Age Matter?

Background

With the increase in average life expectancy in recent decades, the proportion of elderly patients requiring liver surgery is rising. The aim of the meta-analysis reported here was to evaluate the safety and efficacy of hepatectomy in elderly patients.

Methods

An extensive electronic search was performed for relevant articles that compare the outcomes of hepatectomy in patients ≥70 years of age with those in younger patients prior to October 2012. Analysis of pooled data was performed with RevMan 5.0.

Results

Twenty-eight observational studies involving 15,480 patients were included in the analysis. Compared with the younger patients, elderly patients experienced more complications (31.8 vs 28.7 %; P = 0.002), mainly as a result of increased cardiac complications (7.5 vs 1.9 %; P < 0.001) and delirium (11.7 vs 4.5 %; P < 0.001). Postoperative major surgical complications (12.6 vs 11.3 %; P = 0.55) and mortality (3.6 vs 3.3 %; P = 0.68) were comparable between elderly and younger patients. For patients with malignancies, both the 5-year disease-free survival (26.5 vs 26.3 %; P = 0.60) and overall survival (39.5 vs 40.7 %; P = 0.29) did not differ significantly between the two groups.

Conclusions

Postoperative major surgical complications, mortality, and long-term results in elderly patients seem to be comparable with those in younger patients, suggesting that age alone should not be considered a contraindication for hepatectomy.