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1.
Michaely HJ Kramer H Weckbach S Dietrich O Reiser MF Schoenberg SO 《Journal of magnetic resonance imaging : JMRI》2008,27(1):148-153
PURPOSE: The purpose of this study is to evaluate the feasibility and image quality of multishot T2-weighted (T2w) renal morphologic imaging based on the acquisition of rotating rectangular strips of k-space data after successive radiofrequency excitations (BLADE technique). MATERIALS AND METHODS: A total of 7 healthy volunteers and 27 patients with suspected renal and renovascular diseases were included in this prospective intraindividual study. All exams were performed at 3.0T in a random order with a standard T2w turbo-spin-echo (TSE) sequence and with a T2w-BLADE sequence with equal spatial resolution. Phantom measurements were performed to measure the objective signal-to-noise ratio (SNR). Two radiologists rated the image sharpness, the flow signal suppression, the presence of artifacts, and the overall image quality of both techniques and determined their preferred sequence. RESULTS: The SNR did not show significant differences. The overall image quality was rated significantly higher for the T2w-BLADE (P < 0.05). Equally, the presence of disturbing artifacts and the sharpness was ranked significantly better for T2w-BLADE than for the T2w-TSE (P < 0.05). The T2w-BLADE was the preferred sequence in 59% of all cases, the T2w-TSE in 9%.T2w-BLADE sequences seem to be superior for the depiction of the kidneys at 3.0T, particularly due to the decreased number of artifacts and sharper delineation of the organs. 相似文献
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Contrast in rapid MR imaging: T1- and T2-weighted imaging 总被引:1,自引:0,他引:1
R B Buxton R R Edelman B R Rosen G L Wismer T J Brady 《Journal of computer assisted tomography》1987,11(1):7-16
Partial saturation (PS) is an imaging technique that is useful in applications that require rapid image acquisitions (imaging time less than 1 min). Image contrast in PS imaging, as in other magnetic resonance methods, depends on the often conflicting effects of differences in proton density, T1, and T2. Previous analyses of pulse sequence optimization to maximize image contrast have assumed 90 degrees pulses and examined the effects of varying repetition times (TR) and echo times (TE). In this paper we present theoretical calculations and images made with a 0.6 T imager to show that the radiofrequency pulse tip angle alpha, and not the pulse sequence timing parameters, is the most important parameter for producing image contrast. For large tip angles (alpha greater than or equal to 60 degrees), contrast is primarily determined by differences in T1, but for small tip angles (alpha approximately equal to 25 degrees), contrast is primarily due to differences in T2. The T2-weighted images can be produced as quickly as T1-weighted images by using a small pulse angle and a long TE; it is not necessary to use a long TR to reduce the effects of T1 differences. Optimum pulse angles are calculated, and the potential advantages and disadvantages of T2-weighted and T1-weighted PS imaging are discussed. 相似文献
4.
Roger J. Ordidge Jay M. Gorell Jean C. Deniau Robert A. Knight Joseph A. Helpern 《Magnetic resonance in medicine》1994,32(3):335-341
In this paper a new method is presented for the relative assessment of brain iron concentrations based on the evaluation of T2 and T2* -weighted images. A multiecho sequence is employed for rapid measurement of T2 and T2*, enabling calculation of the line broadening effect ( T2′). Several groups have failed to show a correlation between T2 and brain iron content. However, quantification of T2′, and the associated relaxation rate R2′, may provide a more specific relative measure of brain iron concentration. This may find application in the study of brain diseases, which cause associated changes in brain iron levels. A new method of field inhomogeneity correction is presented that allows the separation of global and local field inhomogeneities, leading to more accurate T2* measurements and hence, T2′ values. The combination of T2*, and T2-weighted MRI methods enables the differentiation of Parlkinson's disease patients from normal age-matched controls based on differences in iron content within the substantia nigra. 相似文献
5.
Hardman RL El-Merhi F Jung AJ Ware S Thompson IM Friel HT Peng Q 《Journal of magnetic resonance imaging : JMRI》2011,33(4):902-907
Purpose:
To describe a rapid T2*‐weighted (T2*W), three‐dimensional (3D) echo planar imaging (EPI) sequence and its application in mapping local magnetic susceptibility variations in 3 Tesla (T) prostate MRI. To compare the sensitivity of T2*W EPI with routinely used T1‐weighted turbo‐spin echo sequence (T1W TSE) in detecting hemorrhage and the implications on sequences sensitive to field inhomogeneities such as MR spectroscopy (MRS).Materials and Methods:
B0 susceptibility weighted mapping was performed using a 3D EPI sequence featuring a 2D spatial excitation pulse with gradients of spiral k‐space trajectory. A series of 11 subjects were imaged using 3T MRI and combination endorectal (ER) and six‐channel phased array cardiac coils. T1W TSE and T2*W EPI sequences were analyzed quantitatively for hemorrhage contrast. Point resolved spectroscopy (PRESS MRS) was performed and data quality was analyzed.Results:
Two types of susceptibility variation were identified: hemorrhagic and nonhemorrhagic T2*W‐positive areas. Post‐biopsy hemorrhage lesions showed on average five times greater contrast on the T2*W images than T1W TSE images. Six nonhemorrhage regions of severe susceptibility artifact were apparent on the T2*W images that were not seen on standard T1W or T2W images. All nonhemorrhagic susceptibility artifact regions demonstrated compromised spectral quality on 3D MRS.Conclusion:
The fast T2*W EPI sequence identifies hemorrhagic and nonhemorrhagic areas of susceptibility variation that may be helpful in prostate MRI planning at 3.0T. J. Magn. Reson. Imaging 2011;33:902–907. © 2011 Wiley‐Liss, Inc. 相似文献6.
Cirillo S Petracchini M Scotti L Gallo T Macera A Bona MC Ortega C Gabriele P Regge D 《European radiology》2009,19(3):761-769
To evaluate diagnostic performance of endorectal magnetic resonance (eMR) for diagnosing local recurrence of prostate cancer
(PC) in patients with previous radical prostatectomy (RP) and to assess whether contrast-enhanced (CE)-eMR improved diagnostic
accuracy in comparison to unenhanced study. Unenhanced eMR data of 72 male patients (mean of total PSA: 1.23 ± 1.3 ng/ml)
with previous RP were interpreted retrospectively and classified either as normal or suspicious for local recurrence. All
eMR examinations were re-evaluated also on CE-eMR 4 months after the first reading. Images were acquired on a 1.5-T system.
These data were compared to the standard of reference for local recurrence: prostatectomy bed biopsy results; choline positron
emission tomography results; PSA reduction or increase after pelvic radiotherapy; PSA modification during active surveillance.
Sensitivity, specificity, predictive positive value, negative predictive value and accuracy were 61.4%, 82.1%, 84.4%, 57.5%
and 69.4% for unenhanced eMR and 84.1%, 89.3%, 92.5%, 78.1% and 86.1% for CE-eMR. A statistically significant difference was
found between accuracy and sensitivity of the two evaluations (χ2 = 5.33; p = 0.02 and χ2 = 9.00; p = 0.0027). EMR had great accuracy for visualizing local recurrence of PC after RP. CE-eMR improved diagnostic performance
in comparison with T2-weighted imaging alone. 相似文献
7.
The authors evaluated soft-tissue contrast on spin-echo (SE) proton density-weighted, SE T2-weighted, SE short-echo-time (TE) T1-weighted, and gradient-echo (GRE) images of 34 patients with known hepatic tumors who underwent high-field-strength (1.5-T) magnetic resonance imaging. For solid liver tumors, the difference in the mean lesion-liver contrast-to-noise ratios (C/Ns) with T1- (GRE and SE) and T2-weighted pulse sequences was not statistically significant (P greater than .05). For nonsolid liver tumors, the T2-weighted images provided significantly greater (P less than .05) mean lesion-liver C/N than T1-weighted GRE images. Mean liver signal-to-noise ratio was significantly greater on T1-weighted GRE (P less than .0001) and T1-weighted SE (P less than .05) images than on T2- and proton density-weighted images. Qualitative analysis of T1-weighted (SE and GRE) images and proton density- plus T2-weighted images showed that lesion conspicuity was similar in 25 of 32 patients (78%). The results suggest that liver tumor imaging at high field strength can be performed with short-TE T1-weighted (SE or GRE) or conventional T2-weighted pulse sequences. 相似文献
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N A Matheijssen A de Roos E E van der Wall J Doornbos P R van Dijkman A V Bruschke A E van Voorthuisen 《Magnetic resonance in medicine》1991,17(2):460-469
Magnetic resonance images were obtained from 32 patients with acute myocardial infarction, using a four-echo technique (echo time (TE) = 30, 60, 90, and 120 ms) pregadolinium(Gd)-DTPA injection and a TE = 30 ms sequence pre- and post-Gd-DTPA. Intensity ratios of infarcted and normal myocardium were calculated, as were contrast-to-noise and signal-to-noise ratios. The four intensity ratios pre-Gd-DTPA were 1.20 +/- 0.15, 1.42 +/- 0.22, 1.78 +/- 0.38, and 1.99 +/- 0.60 for TE = 30, 60, 90, and 120 ms, respectively, and 1.42 +/- 0.19 post-Gd-DTPA (p = NS for post-Gd-DTPA vs TE = 60, p = 0.007 for TE = 90 vs TE = 120, p less than 0.0001 for all other comparisons). The four contrast-to-noise ratios pre-Gd-DTPA were 1.69 +/- 0.97, 2.69 +/- 1.13, 3.17 +/- 1.15, and 2.90 +/- 1.09 for TE = 30, 60, 90, and 120 ms, respectively, and 2.71 +/- 1.26 post-Gd-DTPA (p = NS for post-Gd-DTPA vs TE = 60, 90, and 120, p = NS for TE = 120 vs TE = 60 and 90, p less than 0.01 for all other comparisons). The four signal-to-noise ratios pre-Gd-DTPA were 8.67 +/- 1.47, 6.52 +/- 0.76, 5.20 +/- 0.64, 4.17 +/- 0.53 for TE = 30, 60, 90, and 120 ms, respectively, and 9.17 +/- 1.92 post-Gd-DTPA (p = 0.03 for post-Gd-DTPA vs TE = 30, p less than 0.0001 for all other comparisons). In conclusion, the detectabilities of acute myocardial infarction were similar at TE = 60 ms and at Gd-DTPA enhanced short-TE MR imaging. However, image quality proved to be superior using the Gd-DTPA enhanced short-TE technique. 相似文献
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John Conklin Jeff D Winter R Terry Thompson Neil Gelman 《Magnetic resonance in medicine》2008,59(5):1190-1196
Optimization of magnetization-prepared rapid gradient-echo (MP-RAGE) sequence variations for maximum white matter (WM) versus gray matter (GM) contrast in neonates at 3T was investigated. Numerical simulations were applied to optimize and compare three contrast preparation modules and to assess the effect of phase encoding (PE) order on contrast between WM and thin cortical GM layers. Simulations predict that a new sequence, which combines both T(1)- and T(2)-weighting into the contrast preparation and utilizes an interleaved elliptical-spiral PE order, should provide the strongest contrast between neonatal WM and cortical GM. This sequence was compared to a conventional MP-RAGE acquisition (i.e., T(1)-weighted preparation, centric PE order) for in vivo imaging of seven preterm newborn infants. Regional measurements of the contrast-to-noise ratio (CNR) between WM and GM demonstrated an increase of 50-70% (depending on GM region) using the new sequence, in good agreement with theoretical predictions. This improved contrast resulted in superior WM versus GM discrimination in intensity-based brain tissue segmentations. 相似文献
10.
Purpose
To evaluate revised PROPELLER (RevPROP) for T2-weighted imaging (T2WI) of the prostate as a substitute for turbo spin echo (TSE).Materials and methods
Three-Tesla MR images of 50 patients with 55 cancer-suspicious lesions were prospectively evaluated. Findings were correlated with histopathology after MRI-guided biopsy. T2 RevPROP, T2 TSE, diffusion-weighted imaging, dynamic contrast enhancement, and MR-spectroscopy were acquired. RevPROP was compared to TSE concerning PI-RADS scores, lesion size, lesion signal-intensity, lesion contrast, artefacts, and image quality.Results
There were 41 carcinomas in 55 cancer-suspicious lesions. RevPROP detected 41 of 41 carcinomas (100%) and 54 of 55 lesions (98.2%). TSE detected 39 of 41 carcinomas (95.1%) and 51 of 55 lesions (92.7%). RevPROP showed fewer artefacts and higher image quality (each p?<?0.001). No differences were observed between single and overall PI-RADS scores based on RevPROP or TSE (p?=?0.106 and p?=?0.107). Lesion size was not different (p?=?0.105). T2-signal intensity of lesions was higher and T2-contrast of lesions was lower on RevPROP (each p?<?0.001).Conclusion
For prostate cancer detection RevPROP is superior to TSE with respect to motion robustness, image quality and detection rates of lesions. Therefore, RevPROP might be used as a substitute for T2WI.Key points
? Revised PROPELLER can be used as a substitute for T2-weighted prostate imaging.? Revised PROPELLER detected more carcinomas and more suspicious lesions than TSE.? Revised PROPELLER showed fewer artefacts and better image quality compared to TSE.? There were no significant differences in PI-RADS scores between revised PROPELLER and TSE.? The lower T2-contrast of revised PROPELLER did not impair its diagnostic quality.11.
Burstein D Williams A McKenzie C Woertler K Rummeny EJ 《Radiology》2004,233(2):619-20; author reply 621-2
12.
Spiral imaging has a number of advantages for fast imaging, including an efficient use of gradient hardware. However, inhomogeneity-induced blurring is proportional to the data acquisition duration. In this paper, we combine spiral data acquisition with a RARE echo train. This allows a long data acquisition interval per excitation, while limiting the effects of inhomogeneity. Long spiral k-space trajectories are partitioned into smaller, annular ring trajectories. Each of these annular rings is acquired during echoes of a RARE echo train. The RARE refocusing RF pulses periodically refocus off-resonant spins while building a long data acquisition. We describe both T2-weighted single excitation and interleaved RARE spiral sequences. A typical sequence acquires a complete data set in three excitations (32 cm FOV, 192 × 192 matrix). At a TR = 2000 ms, we can average two acquisitions in an easy breath-hold interval. A multifrequency reconstruction algorithm minimizes the effects of any off-resonant spins. Though this algorithm needs a field map, we demonstrate how signal averaging can provide the necessary phase data while increasing SNR. The field map creation causes no scan time penalty and essentially no loss in SNR efficiency. Multiple slice, 14-s breath-hold scans acquired on a conventional gradient system demonstrate the performance. 相似文献
13.
Acute cholecystitis at T2-weighted and manganese-enhanced T1-weighted MR cholangiography: preliminary study 总被引:4,自引:0,他引:4
Twelve patients with symptoms of acute cholecystitis underwent heavily T2-weighted and mangafodipir trisodium-enhanced T1-weighted magnetic resonance (MR) cholangiography and cholescintigraphy before they underwent cholecystectomy. On T2-weighted MR cholangiographic images, morphologic evidence of outflow obstruction of the gallbladder was definitive in seven patients, equivocal in one, and absent in four. In all 12 patients, biliary dynamics depicted at manganese-enhanced T1-weighted MR cholangiography agreed completely with those depicted at hepatobiliary scintigraphy. T2-weighted MR cholangiography combined with manganese-enhanced T1-weighted MR cholangiography provides not only morphologic information but also functional information about the biliary system. 相似文献
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This article reviews the clinical utility of 3D magnetic resonance imaging (MRI) sequences optimized for the evaluation of various intraspinal lesions. First, intraspinal tumors with hypervascular components and arteriovenous malformations (AVM) are clearly shown on contrast-enhanced (CE)-3D T1-weighted gradient-echo (GE) sequences with high spatial resolution. Second, dynamic CE-3D time-resolved magnetic resonance angiography (MRA) shows delineated feeding arteries of intraspinal AVM or arteriovenous fistula (AVF), greatly aiding subsequent digital subtraction angiography (DSA). Third, 3D multiecho T2*-weighted GE sequences are used to visualize intraspinal structures and spinal cord lesions and are sensitive to the magnetic susceptibility of intraspinal hemorrhages. Three-dimensional balanced steady-state free precession (SSFP) and multishot 3D balanced non-SSFP sequences produce contiguous thin images with high signal-to-noise ratio (SNR) in short scanning times. Intraspinal cystic lesions and small nerve-root tumors in subarachnoid space can be viewed using 3D balanced SSFP. Spinal cord myelomalacia and cord compression can be evaluated on fat-suppressed multishot 3D balanced non-SSFP. Finally, a 3D T2-weighted fast spin-echo (FSE) sequence with variable flip angle (FA) refocusing pulse improves through-plane spatial resolution over conventional 2D T2-weighted FSE sequences while matching image contrast. 相似文献
15.
Markkola AT Aronen HJ Lukkarinen S Ramadan UA Tanttu JI Sepponen RE 《Investigative radiology》2001,36(9):531-538
RATIONALE AND OBJECTIVES: Spin lock imaging has been shown to be useful in characterizing head and neck tumors. The purposes of this study were to explore and develop multiple-slice spin lock gradient-echo (SL-GRE) sequences for head and neck imaging and to compare the tumor contrast on SL images to spin-echo (SE) T2-weighted images at 0.1 T. METHODS: On the basis of measured relaxation times of tumors and head and neck tissues, the authors evaluated with signal equations the effect of imaging parameters on tissue contrast produced by the SL-GRE sequence. In the clinical study, 34 patients with pathologically verified head and neck tumors were imaged with multiple-slice SL-GRE (repetition time 1500 ms/echo time 30 ms) out-of-phase fat/water sequences and compared with T2-weighted SE (repetition time 1500 ms/echo time 120 ms) sequences. The conspicuity of tumors was evaluated by calculating the contrast-to-noise ratios (CNRs). RESULTS: The combination of a short echo time of 30 ms and the length of locking pulses in the range of 10 to 35 ms produced optimal CNRs for head and neck tumor imaging. The measured CNRs and subjective evaluation for tumor detection were satisfactory with both imaging sequences. However, the CNRs between tumors and salivary gland tissues were significantly greater with the SL sequence than with the T2-weighted sequence. CONCLUSIONS: The multiple-slice SL-GRE technique provides image contrast comparable to that of SE T2-weighted imaging for head and neck tumors at 0.1 T. With short locking pulse lengths and echo times, wide anatomic coverage and reduced motion and susceptibility artifacts can be achieved. The out-of-phase SL technique is useful in imaging salivary gland tumors. 相似文献
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T1-weighted fluid-attenuated inversion recovery at low field strength: a viable alternative for T1-weighted intracranial imaging 总被引:5,自引:0,他引:5
Hori M Okubo T Uozumi K Ishigame K Kumagai H Araki T 《AJNR. American journal of neuroradiology》2003,24(4):648-651
BACKGROUND AND PURPOSE: T1-weighted spin-echo imaging has been widely used to study anatomic detail and abnormalities of the brain; however, the image contrast of this technique is often poor, especially at low field strengths. We tested a new pulse sequence, T1-weighted fluid-attenuated inversion recovery (FLAIR), which provides good contrast between lesions, surrounding edematous tissue, and normal parenchyma at low field strengths and at acquisition times comparable to those of T1-weighted spin-echo imaging. METHODS: Thirteen patients with brain lesions underwent T1-weighted spin-echo and T1-weighted FLAIR imaging during the same imaging session. T1-weighted spin-echo and T1-weighted FLAIR images were compared on the basis of four quantitative (lesion-white matter [WM] contrast-to-noise ratio [CNR], lesion-CSF CNR, gray matter-WM CNR, and WM-CSF CNR) and three qualitative criteria (conspicuousness of lesions, image artifacts, and overall image contrast). RESULTS: CNRs obtained with T1-weighted FLAIR were comparable but statistically superior to those obtained with T1-weighted spin-echo imaging. In general, T1-weighted FLAIR and T1-weighted spin-echo imaging produced comparable image artifacts. Conspicuousness of lesions and the overall image contrast were judged to be superior on T1-weighted FLAIR images. CONCLUSION: T1-weighted FLAIR imaging may be a valuable alternative to conventional T1-weighted imaging, because the former technique offers superior image contrast at low field strengths and comparable acquisition times. 相似文献
18.
Christof Müller-Leisse Klaus Bohndorf Achim Stargardt Michael Sohn Jrg Neuerburg Gerd Adam Berthold Wein Reinhard Urhahn Rolf W. Günther 《Journal of magnetic resonance imaging : JMRI》1994,4(3):389-395
To evaluate the use of gadopentetate dimeglumine in magnetic resonance (MR) imaging of scrotal disorders, the clinical, ultrasound, and MR imaging data of 29 patients (age range, 19–75 years) with various intra- and extratesticular disorders were retrospectively analyzed. T1- and T2-weighted spin-echo images (T1-T2 group) were compared with T1-weighted spin-echo images before and after intravenous administration of gadopentetate dimeglumine (T1-Gd group). A receiver operating characteristic (ROC) analysis of the findings was undertaken. Better contrast between tumor and parenchyma and a clearer demonstration of the tunica albuginea were noted in the T1-T2 group (although not of diagnostic relevance). ROC analysis revealed no differences between the two imaging groups in the diagnosis of tumor, trauma, hydrocele, or hemorrhage; however, epididymitis was diagnosed more easily with contrast enhancement (0.8834 vs 0.7759, P = .04) and the diagnosis of orchitis was expressed more strongly (0.8221 vs 0.7184, P = .17). Four of the five observers were more confident in making the diagnosis with contrast enhancement. With MR imaging, the diagnosis was correctly suggested in three patients in whom clinical and ultrasound data were inconclusive. Gadolinium-enhanced MR imaging gives additional information in scrotal disorders and facilitates diagnosis. It may be helpful when findings at physical examination and ultrasound differ and when plain T1- and T2-weighted images are equivocal. 相似文献
19.
Breast lesions: evaluation with dynamic contrast-enhanced T1-weighted MR imaging and with T2*-weighted first-pass perfusion MR imaging 总被引:10,自引:0,他引:10
Kvistad KA Rydland J Vainio J Smethurst HB Lundgren S Fjøsne HE Haraldseth O 《Radiology》2000,216(2):545-553
PURPOSE: To evaluate the diagnostic value of an imaging protocol that combines dynamic contrast-enhanced T1-weighted magnetic resonance (MR) imaging and T2*-weighted first-pass perfusion imaging in patients with breast tumors and to determine if T2*-weighted imaging can provide additional diagnostic information to that obtained with T1-weighted imaging. MATERIALS AND METHODS: One hundred thirty patients with breast tumors underwent MR imaging with dynamic contrast-enhanced T1-weighted imaging of the entire breast, which was followed immediately with single-section, T2*-weighted imaging of the tumor. RESULTS: With T2*-weighted perfusion imaging, 57 of 72 carcinomas but only four of 58 benign lesions had a signal intensity loss of 20% or more during the first pass, for a sensitivity of 79% and a specificity of 93%. With dynamic contrast-enhanced T1-weighted imaging, 64 carcinomas and 19 benign lesions showed a signal intensity increase of 90% or more in the first image obtained after the administration of contrast material, for a sensitivity of 89% and a specificity of 67%. CONCLUSION: T2*-weighted first-pass perfusion imaging can help differentiate between benign and malignant breast lesions with a high level of specificity. The combination of T1-weighted and T2*-weighted imaging is feasible in a single patient examination and may improve breast MR imaging. 相似文献
20.
Abdel-Aty H Simonetti O Friedrich MG 《Journal of magnetic resonance imaging : JMRI》2007,26(3):452-459
Technical advances in T2-weighted cardiovascular MR (CMR) imaging allow for accurate identification and quantification of tissue injuries that alter myocardial T2 relaxation. Of these, myocardial edema is of special relevance. Increased myocardial water content is an important feature of ischemic as well as nonischemic cardiomyopathies, which are often associated with acute myocardial inflammation. In this article, we review technical considerations and discuss clinical indications of myocardial T2-weighted imaging. 相似文献