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A Kasper M Pelizzone P Montandon 《ORL; journal for oto-rhino-laryngology and its related specialties》1992,54(6):285-294
Electrically evoked auditory brainstem responses (EABR) were recorded in completely deaf patients implanted with Ineraid multichannel cochlear implants. Clear and reproducible EABR were obtained from all patients. Parametric differences with auditory brainstem responses (ABR) were demonstrated and can be explained by the different natures of both types of stimulations (electric versus acoustic). Evidence is given that other well-known properties of auditory evoked responses, like 'binaural interaction' or suppression of responses in a forward masking paradigm, can be observed in EABR of implanted patients. 相似文献
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Measurement of auditory brainstem responses evoked by electrical stimulation with a cochlear implant
Auditory brainstem responses evoked by electrical stimulation with a Nucleus/Cochlear implant can be measured if care is taken to prevent stimulus artefacts. A simple procedure is described which relies upon a passive LCR filter to prevent the radiofrequency carrier from entering the input of the recording amplifier. The filter simply prevents saturation of the amplifier by the carrier. 相似文献
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Ossification of the cochlea following meningitis presents a surgical challenge. Electrode mapping, especially in the young child, is difficult given the uncertainty of electrode contact with viable neural elements. This paper reviews surgical technique and the use of auditory brainstem responses to map the electrodes. A 4-year-old child deafened by meningitis at age 20 months had bilateral cochlear ossification by computed tomography. At surgery, a canal wall-down mastoidectomy and closure of the ear canal were performed. A trough around the modiolus was drilled, and the electrode array was placed in it. Post-operatively, the patient gave aversive or no responses to electrode stimulation. To assess electrode function, auditory brainstem responses to individual electrode activation were obtained under general anesthesia. Functioning electrodes could thus be selected for mapping. The patient now responds well to sound. 相似文献
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Bilateral cochlear implants aim to restore binaural processing along the auditory pathways in children with bilateral deafness. We assessed auditory brainstem activity evoked by single biphasic pulses delivered by an apical or basal electrode from the left, right and both cochlear implants in 13 children. Repeated measures were made over the first 9-30 months of bilateral implant use. In children with short or long periods of unilateral implant use prior to the second implantation, Wave eV of the auditory brainstem response was initially prolonged when evoked by the na?ve versus experienced side. These differences tended to resolve in children first implanted <3 years of age but not in children implanted at older ages with long delays between implants. Latency differences were projected to persist for longer periods in children with long delays between implants compared with children with short delays. No differences in right versus left evoked eV latency were found in 2 children receiving bilateral implants simultaneously and their response latencies decreased over time. Binaural interaction responses showed effects of stimulating electrode position (responses were more detectable when evoked by an apical than basal pair of implant electrodes), and duration of delay between implants (measured by latency delays). The trends shown here suggest a negative impact of unilateral implant use on bilateral auditory brainstem plasticity. 相似文献
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Shujiro B Minami Hideki Takegoshi Yukiko Shinjo Chieko Enomoto Kimitaka Kaga 《Acta oto-laryngologica》2015,135(10):1007-1015
Conclusions: EABR is a reliable and effective way of objectively confirming device function and implant-responsiveness of the peripheral auditory neurons up to the level of the brainstem in cases of inner ear malformation. Objective: To investigate the usefulness of measuring the intra-operative electrically evoked compound action potential (ECAP) and electrically evoked auditory brainstem response (EABR) in patients with and without congenital inner ear anomalies during cochlear implantation. Method: Thirty-eight consecutive children (40 ears) aged 5 or younger with congenital profound hearing loss. Twenty-four (25 ears) lacked congenital inner ear anomalies. The 14 patients (15 ears) with a malformation had common cavities (four ears), incomplete partition type I (three ears), cochlea hypoplasia type III (three ears), enlarged vestibular aqueduct (four ears), and cochlear nerve canal stenosis (one ear). Main outcome measures are ECAP and EABR responses. Results: Of the 25 ears lacking any malformation, 21, three, and one showed ‘Good’, ‘Variable’, and ‘No’ ECAP responses, respectively, and 24 and one showed ‘Good’ and ‘Variable’ intra-cochlear responses, respectively. Of the 15 ears with a malformation, two showed ‘Good’ ECAP responses, nine had ‘Variable’ ECAP responses, and four showed ‘No’ ECAP responses. Moreover, five showed ‘Good’ EABR responses and 10 showed ‘Variable’ EABR responses. 相似文献
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The protocol for assessing patients for cochlear implantation at University College Hospital and the Royal National Institute for the Deaf, London, includes a session of electrophysiological tests and electrical stimulation of the cochlea. Electrocochleography is performed with the object of excluding non-organic hearing loss and of clarifying the site of deafness. Using the same transtympanic needle, AC and DC electrical stimulation is performed to establish whether patients perceive a sensation of sound, dynamic range and ability to detect frequency shifts. Tinnitus suppression was produced by AC and DC stimulation. It is likely that AC suppression of tinnitus occurs by a masking effect. Electrically evoked auditory brainstem potentials were recorded in one patient. 相似文献
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Positron emission tomography (PET) imaging was used to evaluate the brain's response to auditory stimulation, including speech. Five cases of adults illustrate the utility of PET to illuminate auditory processing with cochlear or brainstem implants. Subjects showed varying degrees of success in processing speech, which was reflected in the resulting PET images. Functional speech processing was associated with activation in areas classically associated with speech processing. In one patient who did not achieve functional speech processing, activation in frontal regions suggests that the subject used other cognitive strategies to assist auditory processing. Learning outcomes: As a result of this activity, the participant will be introduced to the principles of PET and the application of this technology to deaf patients who have received an implanted auditory prosthesis. 相似文献
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AimRecording of the electrically evoked compound action potential (ECAP) of the auditory nerve in cochlear implant (CI) patients represents an option to assess changes in auditory nerve responses and the interaction between the electrode bundle and the neural tissue over time. The aim of the present work is to assess ECAP changes during the first year of cochlear implant for the purpose of predicting thresholds and adjustment of the patients’ programs over time.MethodData were collected from 25 children using Cochlear Nucleus 24 implants. ECAP thresholds were examined at the time of surgery, at initial stimulation, and 3, 6 and 12 months post-stimulation. Five electrodes located at basal, middle, and apical positions in the cochlea were tested at each time interval and ECAP thresholds were analyzed and compared.ResultsThere was a significant decrease in ECAP thresholds between the intraoperative measure and fitting time at all electrode sites. Mean ECAP thresholds measured at 3, 6 and 12 months post-stimulation remained similar to initial stimulation levels. Although there was no significant difference in ECAP thresholds recorded at fitting time and 12 months follow up session, there was significant increase in behavioral T and C levels from initial stimulation to the 12 months’ time point.ConclusionMost electrodes undergo non-significant change in ECAP thresholds over time, and therefore thresholds obtained on the day of initial stimulation can be used to estimate the patients’ map levels at any time. On the other hand, intraoperative thresholds demonstrated significant change relative to postoperative recording times, limiting the ability to use intraoperatively recorded ECAP thresholds to predict postoperative measurements. 相似文献
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Electric middle-latency auditory evoked responses (EMLRs) to transtympanic promontory stimulation were obtained from 19 of 22 ears of profoundly hearing-impaired patients evaluated for cochlear implant candidacy. The EMLRs were characterized by positive polarity peaks with latencies ranging from 20 to 30 ms, with the majority of responses exhibiting peaks in the range of 26 to 30 ms. Generally, the configuration of the EMLRs closely resembled the configuration of acoustic MLRs. While in most cases, behavioral thresholds to identical promontory stimulation were slightly lower, EMLR thresholds closely approximated behavioral electrical promontory thresholds. The EMLR thresholds correlated positively with implanted thresholds and exhibited a negative correlation with implanted dynamic current ranges. 相似文献
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Delayed brainstem auditory evoked responses in diabetic patients 总被引:1,自引:0,他引:1
N Buller Y Shvili N Laurian L Laurian Y Zohar 《The Journal of laryngology and otology》1988,102(10):857-860
The incidence of subclinical central diabetic neuropathy is unclear due to difficulty in detecting latent alterations of central neural transmission process. The aim of this study was to evaluate a central neuroconductive mechanism in diabetics by brainstem auditory evoked responses (BAER). We found increased latencies of peaks I, III, V in diabetics as compared to control subjects. These BAER abnormalities were demonstrated in 62 per cent of insulin-controlled diabetics and in 33 per cent o patients treated by diet, or peroral drugs. No alterations in brainstem responses were observed in patients with latent diabetes. We did not find any correlation between the BAER abnormalities and the duration of the disease, the blood glucose level or the level of control of the diabetes. 相似文献
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M D Waring 《The Laryngoscope》1992,102(11):1293-1295
Evoked potentials identified as electrically evoked auditory brainstem responses (EABRs) have been recorded from a patient in response to electrical stimulation of the cochlear nucleus via an auditory brainstem implant. Recording such EABRs during surgery for removal of an ipsilateral facial nerve tumor provided a means to monitor the integrity of the implant. The presence of stable EABRs similar to those obtained before surgery indicated that the lead wires had not been severed and that the implanted electrodes had not been dislodged. EABR recording may also be useful for assisting with positioning the stimulating electrodes during initial implantation surgery, by verifying that stimulation can activate the auditory system. 相似文献
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The electrically evoked brainstem potential was measured in cochlear implant patients with Symbion multichannel electrode system. In the first experiment, electrodes within the implant were stimulated individually and the responses and sensitivity across electrodes and across subjects were evaluated. The typical response waveform consisted of a series of three peaks, the most prominent occurring at approximately 4 ms after stimulus onset. The amplitude of the largest peak typically showed an orderly increase with increasing current level while latency changes were relatively small. In the second experiment, two electrodes were stimulated simultaneously in order to evaluate the relative independence of the neural populations being stimulated by the different electrode pairs. The responses were compared when two electrode pairs were stimulated simultaneously with current pulses in phase and when the same electrodes were stimulated with current pulses inverted relative to each other. Both stimulation conditions showed similar growth in response amplitude with level but different sensitivity. The differences in sensitivity between these two conditions may be indicative of the degree of overlap in the stimulated neural populations. 相似文献
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Significance of auditory evoked responses (EABR and P300) in cochlear implant subjects 总被引:6,自引:0,他引:6
An electrically derived auditory brainstem response (EABR) was recorded intra-operatively, and the event-related potential (P300) postoperatively in post-lingually deaf adult cochlear implantees. EABR and P300 were recorded from two groups of 25 subjects each. All subjects had a cochlear mini-22 system implanted at our center between 1994 and 1998. Two parameters of EABR, threshold (T) and the gradient of the amplitude-growth (AG) curve, were used for correlation with postoperative speech reception scores. The consonant recognition score (CRS) measured 1 month postoperatively showed a significant correlation with the AG curve of EABR (Spearman rank order test, p = 0.004), but not at later points in time. No correlation was found between the T and CRS at any time postoperatively. As the AG curve reflects the number of remaining spiral ganglion cells in the inner ear, a large number of surviving neurons is thought to be advantageous only for initial speech learning. The latency of P300 was measured for correlation with the speech reception score. The division of the cochlear implant subjects into a fair and a good hearing group according to their CRS showed that the average latency of P300 was significantly longer for the fair hearing group than for the good hearing group. A follow-up study showed that P300 latency significantly correlated with CRS measured at 6 months, 1 year and at a later time. As the latency of P300 is thought to reflect the time for sound processing in the central auditory system, our results indicate that plasticity of the central auditory system is more important than that of the peripheral auditory system for speech learning in cochlear implant subjects. 相似文献