根管长度电测法准确性及其影响因素的探讨

目的:探讨JUSTY-Ⅱ电测仪测量根管工作长度的准确性及其影响因素。方法:选择148颗患牙,其中牙髓炎71颗,牙髓坏死46颗,根尖周炎31颗。随机分为2组,分别用指感法和电测法测量根管工作长度,以X线片影像为参照,用χ2检验比较其结果,并分析各临床病变类型、根管干湿状态和根管扩大等因素对电测法准确性的影响。结果:电测法准确率为87.84%,指感法为43.24%,2组有高度显著性差异(P<0.01)。根尖周炎组准确率与牙髓炎组、牙髓坏死组有显著性差异(P<0.05)。根管干湿状态对测量结果无影响,扩根前后准确率有显著性差异(P<0.05)。结论:电测法是一种准确、操作简便的测量根管工作长度的方法。根尖周组织的炎症以及根管扩大,均会降低其准确性。     

Endodontic treatment of an invaginated maxillary lateral incisor with a periradicular lesion and a healthy pulp

AIM: To report the healing of a periradicular lesion following nonsurgical root canal treatment of a dental invagination. SUMMARY: A case of dens invaginatus type 3 with a periradicular lesion and a healthy pulp is reported. Nonsurgical root canal treatment of the invagination was performed successfully and resolved an associated periradicular lesion. Despite the complex anatomy and a diagnosis of apical periodontitis, pulp health was retained after endodontic treatment of the invaginated canal. Clinical considerations and treatment are discussed and reported. KEY LEARNING POINTS: Dens invaginatus can present in a variety of forms, knowledge of which can usefully inform endodontic diagnosis and treatment. In certain cases, success can be achieved by treating the invagination alone. Pulp health may be preserved during and after treatment of an infected invagination.     

一次性和多次性根管治疗应用于根尖周炎的临床评价

目的评价根管治疗一次法和多次法对无症状根尖周炎疗效的影响,探讨一次性根管治疗的适应症。方法选取无症状根尖周炎的患牙160颗,分层随机法分为两组,分别采用一次法和多次法完成根管治疗。所有患牙均使用镍钛机动根管器械预备,牙胶冷侧方加压法充填根管。比较两组术后疼痛发生情况,根据患者主观症状、临床表现和术前术后X线片评价疗效。结果一次法和多次法在术后疼痛、根管治疗效的差异上没有统计学意义。结论一次性根管治疗应用于无症状根尖周炎的患牙是可行的,但要注意控制适应症。     

Prevalence of Apical Periodontitis in Root Canal–Treated Teeth From an Urban French Population: Influence of the Quality of Root Canal Fillings and Coronal Restorations

This cross-sectional study determined the prevalence of apical periodontitis in 1035 root canal–treated teeth from adult French patients and investigated the influence of the quality of canal fillings and coronal restorations on the periradicular status. Periapical radiographs were used for analyses, and teeth were classified as healthy or diseased according to the periapical index scoring system. Overall, the prevalence of apical periodontitis in root canal–treated teeth was 33%. Only 19% of the teeth had endodontic treatments rated as adequate. The success rate (number of healthy teeth) for cases with adequate endodontic treatment was 91%, which was significantly higher when compared with teeth with inadequate treatment (61%). Teeth with adequate restorations had significantly decreased prevalence of apical periodontitis (29%) as compared with teeth with inadequate restorations (41%). The combination of adequate endodontic treatment and adequate restorations yielded the highest success rate (93.5%). The quality of the endodontic treatment was the most important factor for success, although the quality of the coronal restoration also influenced the treatment outcome.     

根管治疗期间急性发作与慢性根尖周炎患牙根管细菌组成比较

目的:比较根管治疗期间炎症急性发作及慢性根尖周炎患牙根管内8种厌氧菌检出情况,分析急性发作时根管内定植细菌种类及其相关性。方法:分别提取26例根管预备后约诊期间炎症急性发作患牙根管样本和23例慢性根尖周炎患牙根管样本,提取样本细菌DNA,利用细菌16S rRNA引物通过PCR扩增方法鉴定细菌。结果:慢性根尖周炎样本根管细菌检出率达100%(23/23),根管治疗期间急性发作样本细菌检出率为92.31%(24/26);产黑普氏菌、齿垢密螺旋体和直肠弯曲杆菌在急性发作样本中的检出率较慢性根尖周炎样本显著增高(P<0.05)。急性发作样本中牙龈卟啉菌与福赛氏类杆菌的检出显著相关(OR>2,P<0.05)。结论:根管内感染是根管治疗期间炎症急性发作的重要原因,厌氧菌在急性发作的发生中起重要作用。     

Treatment of a Large Cystlike Inflammatory Periapical Lesion Associated with Mature Necrotic Teeth Using Regenerative Endodontic Therapy

Introduction

Regenerative endodontic therapy is currently used to treat immature permanent teeth with necrotic pulp and/or apical periodontitis. However, mature teeth with necrotic pulp and apical periodontitis have also been treated using regenerative endodontic therapy. The treatment resulted in resolution of apical periodontitis, regression of clinical signs and symptoms but no apparent thickening of the canal walls, and/or continued root development. A recent study in an animal model showed that the tissues formed in the canals of mature teeth with apical periodontitis after regenerative endodontic therapy were cementumlike, bonelike, and periodontal ligament–like tissue with numerous blood vessels. These tissues are similar to the tissues observed in immature permanent teeth with apical periodontitis after regenerative endodontic therapy.

Methods

A 23-year-old woman had a history of traumatic injury to her upper anterior teeth when she was 8 years old. Subsequently, #8 developed pulp necrosis and an acute apical abscess and #7 symptomatic apical periodontitis. The apex of #8 was slightly open, and the apex of #7 was completely formed. Instead of nonsurgical root canal therapy, regenerative endodontic therapy was attempted, including complete chemomechanical debridement on #8 and #7. This was based on the premise that filling of disinfected root canals with the host's biological vital tissue might be better than filling with foreign materials.

Results

After regenerative endodontic therapy of #8 and #7, there was radiographic evidence of periapical osseous healing and regression of clinical signs and symptoms. The pulp cavity of #8 decreased in size, and the apex closed. The pulp cavity of #7 appeared to be obliterated by mineralized tissue. These indicated ingrowth of new vital tissue into the chemomechanically debrided canals.

Conclusions

Regenerative endodontic therapy of mature teeth with apical periodontitis and apical abscess can result in the regression of clinical signs and/or symptoms and healing of apical periodontitis but no apparent thickening of the canal walls or continued root development. Filling of the disinfected canals with the host's vital tissue may be better than with foreign materials because vital tissue has innate and adaptive immune defense mechanisms.     

Bacteria recovered from teeth with apical periodontitis after antimicrobial endodontic treatment

Chávez de Paz LE, Dahlén G, Molander A, Möller Å, Bergenholtz G . Bacteria recovered from teeth with apical periodontitis after antimicrobial endodontic treatment. International Endodontic Journal, 36 , 500–508, 2003. Aim To determine whether there is a pattern for certain bacteria to remain after chemo‐mechanical treatment of root canals in teeth with apical periodontitis. Methodology Consecutive root‐canal samples of 200 teeth receiving root‐canal treatment, referred from general practitioners and endodontic specialists for analyses of cultivable microbes, were studied prospectively. To be included, samples had to be taken at a treatment session subsequent to the one at which endodontic therapy was initiated. All samples were from teeth that either presented with clinical or radiographic evidence of apical periodontitis or both. Bacteriological findings were linked to clinical and radiographic parameters including status of the root canal prior to treatment, namely, vital pulp, necrotic pulp or root filled. Results A total of 248 strains were isolated from 107 teeth giving bacterial growth. Gram‐positives predominated (85%). Lactobacillus spp. (22%), nonmutans streptococci (18%), and Enterococcus spp. (12%) were the most common isolates. Gram‐negative anaerobes were relatively sporadic. Large radiographic bone lesions, persistent pain and use of intracanal calcium hydroxide dressing correlated with bacterial presence (P < 0.05). Conclusions Once established, nonmutans streptococci, enterococci and lactobacilli appear to survive commonly following root‐canal treatment of teeth with clinical and radiographical signs of apical periodontitis.     

初次根管治疗愈合率和影响因素分析

目的评价进行初次根管治疗的患牙的愈合率,分析影响初次根管治疗愈合的因素。方法选取2005年1月-2007年12月接受初次根管治疗的296例患者的371颗患牙,采用冠向下技术进行根管治疗,随访2年。依据临床检查和X线片评判治疗效果,并分析牙根数目、牙髓活力、根管充填情况、根尖周病变对治疗效果的影响。结果296例患者（371颗牙）中143例患者（176颗牙）参与了回访。复诊病例中有152颗（86.36%）患牙评定为愈合（无临床症状、无根尖周病变）;24颗为病变,其中12颗被拔除,12颗进行再治疗。活髓牙的根管治疗愈合率（95.38%）明显高于死髓牙（81.08%）,根尖周无病变患牙的愈合率（95.24%）明显高于有病变的患牙（73.24%）;单根牙的愈合率与多根牙无明显差异,不同根管充填情况（适充或充填不完善）患牙的愈合率也无明显差异（P>0.05）。结论牙髓和根尖周状况对初次根管治疗的成功率有着较明显的影响。     

A 20-year follow-up study of endodontic variables and apical status in a Swedish population

AIM: To re-examine a population after 20 years and evaluate changes in prevalence of endodontic treatment and apical periodontitis, as well as the technical quality of root fillings. METHODOLOGY: One hundred and fifteen out of an original 200 patients living in the northern part of Sweden were re-examined with a full mouth radiographic survey after 20 years. Frequencies of root canal treated teeth, apical periodontitis and quality parameters of root fillings were registered. RESULTS: The frequency of root canal treated teeth increased significantly (P < 0.05) from 13.9% at the first investigation to 17.7% after 20 years. There was also a statistically significant increase (P < 0.05) in teeth with apical periodontitis from 3.3% to 6.8%. Apical periodontitis both in connection with root canal treated teeth and teeth without endodontic treatment, had increased during the follow-up period. Even though the quality of the root fillings had improved, there was no corresponding improvement of the apical status in teeth with root fillings. CONCLUSIONS: There is still a great need for endodontic treatment in the Swedish population, and no improvement in apical health was found during this 20-year follow up.     

Continued root formation after replantation and root canal treatment in an avulsed immature permanent tooth: a case report

Abstract – This case report describes the continued root formation following replantation and conventional root canal therapy of a traumatically avulsed open‐apex tooth with suppurative apical periodontitis. A 7‐year‐old male patient had an avulsed upper left central incisor (tooth 21) replanted approximately 50 min after traumatic avulsion. A root canal procedure was initiated due to pulp necrosis and periapical abscess detected in the follow‐up period. After endodontic treatment with calcium hydroxide (Ca(OH)₂) dressing, a normal root length developed including an apical segment beyond the hard tissue barrier. Regeneration of the root occurred without pathology or ankylosis at 1‐year of follow up.     

Clinical evaluation of audiometric control root canal treatment: a retrospective case study.

OBJECTIVE: The purpose of this study was to retrospectively assess the success of endodontic treatment that had been guided by audiometric (electronic) measurement. METHOD AND MATERIALS: The lengths of 66 infected root canals that demonstrated periapical pathosis were accurately measured by the Sono-Explorer before root canal obturation. The results over time intervals of 1 month to 20 years were evaluated on the basis of radiographic examinations. RESULTS: The rate of successful treatment was 90.4% for short-filled root canals, 94.5% for flush-filled root canals, and a low 50.0% for long-filled root canals. The rate of successful endodontic therapy was 87.8% for restorations that did not exceed the apical foramen but reached the apical constriction and 95.3% if cases in which the apical radiolucencies were disappearing were included as successes. If cases of unintentional long-filling (overextension) were excluded, the success rate was as high as 98.4%. CONCLUSION: The poor performance of overfilled root canals indicates that practitioners should not overextend these restorations. Use of the Sono-Explorer aided successful treatment of infected root canals.     

Endodontic treatment and prevalence of apical periodontitis in an adult population of Vilnius, Lithuania

Apical periodontitis is prevalent in many Western populations and is frequently detected in connection with inferior quality of endodontic treatment. However, information about endodontic conditions from eastern European countries is limited. The aim of the present investigation was to study the prevalence of apical periodontitis and the quality of endodontic treatment in 35-44-year-old Lithuanians. The prevalence of apical periodontitis was 70%. An overall success rate of 65% was found for root-filled teeth while 56% of pulp amputations (pulpotomies) were considered successful based on a radiographic evaluation. The quality of the root fillings showed little impact on the treatment results, except for over-extended fillings, which were associated with a high number of failures.     

Endodontic treatment and prevalence of apical periodontitis in an adult population of Vilnius, Lithuania

Abstract— Apical periodontitis is prevalent in many Western populations and is frequently detected in connection with inferior quality of endodontic treatment. However, information about endodontic conditions from eastern European countries is limited. The aim of the present investigation was to study the prevalence of apical periodontitis and the quality of endodontic treatment in 35–44-year-old Lithuanians. The prevalence of apical periodontitis was 70%. An overall success rate of 65% was found for root-filled teeth while 56% of pulp amputations (pulpotomies) were considered successful based on a radiographic evaluation. The quality of the root fillings showed little impact on the treatment results, except for over-extended fillings, which were associated with a high number of failures.     

Healing of apical periodontitis after endodontic treatment with and without obturation in dogs

The principle of obturation of the root canal space is generally accepted. This belief has dominated the field of endodontics despite the absence of credible scientific evidence. Little information is available on the possible relationships between endodontic success and obturation of the root canal system. The present study compares the healing of instrumented and obturated versus instrumented and nonobturated root canal systems with apical periodontitis. Fifty-six root canals in 28 third and fourth bilateral lower premolar teeth with completely formed apices in seven mixed German Shepherd dogs were used. Apical lesions were created by accessing the canals, removing the pulp and leaving them open to the oral environment for 42 days. The teeth in the control group were instrumented, irrigated, and then obturated using a lateral condensation technique with gutta-percha cones and AH26 Plus as the endodontic sealer. The teeth in the experimental group were instrumented and irrigated without obturation. All teeth in both groups were sealed coronally. After 190 days, the animals were euthanized. Vital perfusion with 10% formalin through common carotid artery was performed. Thirty to 40 serial 5-microm thick sections were obtained from each root and stained with hematoxylin and eosin for histological evaluation by observer blinded to the treatment allocation. The control group showed less cementum and dentin resorption in comparison with test group (p < 0.5). No statistically significant difference was found in other parameters between the control and test groups (p > 0.05). The noteworthy finding of this study was that there was no difference in healing of apical periodontitis between the instrumented and obturated and instrumented and nonobturated root canal system. The success of endodontic treatment ultimately depends on the elimination of the microorganism, host response and mechanical closure (coronal seal) of treated root canals that may provide a potential for future bacterial contamination.     

Histopathological Condition of the Remaining Tissues after Endodontic Infection of Rat Immature Teeth

Introduction

Recently, case reports have shown that immature teeth diagnosed with necrotic pulp and periapical periodontitis can be repaired through a regenerative endodontic procedure. True regeneration depends on the presence of stem cells in the remaining vital tissues. The aim of this study was to evaluate the histologic condition of the pulp tissue, root apical papilla, and periapical tissues after inducing endodontic infection in immature rat teeth for different periods.

Methods

This study evaluated 18 first upper rat molars (36 roots). Periapical lesions were induced and were confirmed radiographically, and the animals were divided into 3 groups according to the days of pulp exposure for endodontic infection induction: 30, 60, and 90 days. Histologic analysis was performed in 5 different areas (ie, cervical, middle, and apical root canal thirds; the apical papilla; and the periapex surrounding the apical papilla).

Results

At 30 days, one third of the specimens still showed vital but intensely inflamed pulp tissue in the apical third and vital apical papilla with varying degrees of inflammation. After 60 days, the results were similar with respect to the apical pulp tissue and apical papilla. Completely necrotic pulp tissue in the space canal and vital apical papilla were observed in about 67% of the cases after 90 days.

Conclusions

Vital pulp tissue was observed in the apical third until 60 days and in the vital apical papilla until 90 days of infection in a rat model.     

Allogeneic Cellular Therapy in a Mature Tooth with Apical Periodontitis and Accidental Root Perforation: A Case Report

IntroductionCell therapy in regenerative endodontics introduces an alternative option to classic treatment strategies for complex endodontic cases. The aim of this case report was to describe cell-based therapy using allogeneic umbilical cord mesenchymal stem cells (UC-MSCs) encapsulated in a bioscaffold for a complex case of a mature permanent tooth with apical periodontitis and accidental root perforation.MethodsA healthy 19-year-old man undergoing orthodontic treatment was referred for endodontic treatment in tooth #7; he was diagnosed with apical periodontitis during a previously initiated treatment associated with accidental perforation of the radicular cervical third. The root perforation was sealed with glass ionomer and composite resin, and the root canal was instrumented, disinfected, and dressed with calcium hydroxide. After 3 weeks, allogeneic UC-MSCs were encapsulated in platelet-poor plasma and then implanted into the root canal, and Biodentine (Septodont, Saint-Maur-des-Fosses, France) was placed below the cementoenamel junction. Finally, the tooth was restored with composite resin.ResultsFollow-up examinations were performed 6 months and 1 year later. The examinations included periapical radiography, cone-beam computed tomographic imaging, and sensitivity and vitality tests. Radiographic and cone-beam computed tomographic images indicated remission of the apical lesion. Clinical evaluations revealed normal responses to percussion and palpation tests; the tooth was responsive to the electric pulp test, and the vitality test indicated low blood perfusion units.ConclusionsThis case report reveals the potential use of allogeneic cellular therapy using encapsulated UC-MSCS in a platelet-poor plasma scaffold for a complex case of a permanent tooth with apical periodontitis and root perforation.     

Vitapex治疗成年患者根尖孔闭合不全并发慢性根尖周炎的疗效观察

目的：观察Vitapex对成年患者根尖孔闭合不全并发慢性根尖周炎患牙的临床疗效.方法：选择成年患者根尖孔发育不全并发慢性根尖周炎患牙36例,完成根管预备、消毒后,用氢氧化钙类糊剂Vitapex行根尖诱导术.经随访1～3a,在确认根尖有硬组织形成时,行注射式热牙胶根管充填,术后定期复查.结果：根尖发育完成者7例,占19.4%;根尖处有钙化桥形成者27例,占75%;失败2例,占5.6%.总有效率为94.4%,平均治疗周期为13.0周.结论：Vitapex对成年患者根尖孔发育不全并发慢性根尖周炎的患牙具有良好的临床疗效,值得临床推广应用.     

One-appointment endodontic therapy: biological considerations

BACKGROUND: The authors conducted a literature review to present the best available biological evidence concerning one-appointment endodontic therapy for asymptomatic teeth with apical periodontitis. TYPES OF STUDIES REVIEWED: Because of recent advances in technology, such as rotary engines and nickel-titanium instruments, some practitioners are performing one-appointment endodontic therapy for asymptomatic teeth with apical periodontitis. The authors reviewed the literature, which revealed only a small number of randomized, controlled clinical trials that have been conducted on one-appointment versus multiple-appointment endodontic therapy. RESULTS: As the apical canal preparation is enlarged, a greater percentage of bacteria is eradicated from infected root canals. In addition, sufficiently large apical root canal enlargement facilitates the delivery of antimicrobial irrigant to the apical portion of the canal. However, an association between positive or negative preobturation root canal culture results and the outcome of endodontic treatment has not been well-established. CLINICAL IMPLICATIONS: The best available evidence, based on a systematic literature review, indicates that one-appointment endodontic therapy may be feasible in selected cases of apical periodontitis in asymptomatic teeth. However, additional randomized, controlled clinical trials are required.     

An Innovative Regenerative Endodontic Procedure Using Leukocyte and Platelet-rich Fibrin Associated with Apical Surgery: A Case Report

Regenerative endodontic procedures (REPs) associated with apical surgery could represent an alternative treatment strategy for patients whose teeth present incomplete root formation and extensive apical lesions. Leukocyte platelet-rich fibrin (L-PRF) has potential benefits in REPs; it could promote apical root formation and optimal bone healing. The aim of this case report was to describe innovative regenerative endodontic therapy using L-PRF in the root canal and an extensive apical lesion in an immature tooth with dens invaginatus and asymptomatic apical periodontitis. A healthy 20-year-old woman was referred to the dental clinic of the Universidad de Los Andes, Santiago, Chile, for endodontic treatment in tooth # 22 with incomplete root development and an extensive apical lesion. The diagnosis was asymptomatic apical periodontitis associated with dens invaginatus type II. The patient was treated with an innovative approach using L-PRF in REPs associated with apical surgery. Follow-ups were performed at 6 months and 1 year later. They included periapical radiographs, cone-beam computed tomographic imaging, sensitivity, and vitality tests. The clinical evaluations performed at 6 months and 1 year revealed an absence of symptoms. The radiographic evaluations showed that the apical lesion was resolved. The cone-beam images indicated that the root length increased and the walls had thickened. The sensitivity tests were positive, and the laser Doppler flowmetry showed positive blood flow after 1 year. The success of the results in this case report indicate that L-PRF can be used as a complement in apical surgery and REPs and could provide an innovative alternative treatment strategy for complex clinical cases like these.     

脉冲Nd:YAG激光治疗慢性根尖周炎的临床疗效评价

目的 分析脉冲激光治疗慢性根尖周炎的临床疗效.方法 收集门诊68例慢性根尖周炎患者.其中36例常规根管预备后,采用激光辅助治疗和根向激光直接治疗的方法,另外32例则采用常规根管治疗做对照.通过患牙松动度、窦道愈合程度、咀嚼功能以及X线片骨质阴影区评价两者疗效.结果 激光治疗后有效率是88.89%,而常规根管治疗法则为62.50%.结论 脉冲激光对治疗慢性根尖周炎症有辅助作用,可以作为常规根管治疗的辅助手段.