两种联合手术方式治疗急性闭角型青光眼合并白内障的疗效比较

目的：探讨超声乳化白内障吸除人工晶状体植入联合房角分离术治疗原发性急性闭角型青光眼(acute primary angle-closure glaucoma,APACG)合并白内障的临床疗效。

方法：前瞻性随机对照研究。选择符合入组条件的急性闭角型青光眼合并白内障患者60例60眼,随机分为对照组和研究组; 对照组行白内障超声乳化吸除、人工晶状体植入联合小梁切除术(30眼),研究组行白内障超声乳化吸除、人工晶状体植入联合房角分离术(30眼),比较两种术式的临床疗效。

结果：术前两组视力、眼压、中央前房深度、房角开放程度差异无统计学意义(P>0.05); 术后2mo两组视力、眼压、中央前房深度、房角开放程度均明显比术前改善,差异有统计学意义(P<0.001); 研究组术后视力、中央前房深度、房角开放程度,均优于对照组,差异有统计学意义(P<0.05); 两组术后眼压及并发症相比,研究组优于对照组,但差异无统计学意义(P>0.05)。

结论：白内障超声乳化人工晶状体植入联合房角分离术,对APACG合并白内障患者视力的提高、眼压的控制有着积极的临床效果。     

三联术治疗闭角型青光眼合并白内障

目的:评价小切口非超声乳化人工晶状体植入联合小梁切除术治疗闭角型青光眼合并白内障的临床疗效。方法:对20例20眼闭角型青光眼合并白内障采取小切口非超声乳化人工晶状体植入联合小梁切除术进行治疗,术后随访3mo。结果:术后视力较术前提高者占90%,术后1wk眼压全部在正常范围,无严重并发症发生。结论:小切口非超声乳化人工晶状体植入联合小梁切除术可有效治疗闭角型青光眼合并白内障。     

超声乳化人工晶状体植入联合房角分离术治疗闭角型青光眼合并白内障

目的：探讨超声乳化人工晶状体植入术联合房角分离术治疗闭角型青光眼合并白内障的临床效果,为治疗闭角型青光眼合并白内障提供依据。

方法：回顾分析2010-01/2011-10入选本研究的95例112眼闭角型青光眼合并白内障患者的临床资料,对其行超声乳化白内障摘除人工晶状体植入术联合房角分离术治疗,对其疗效进行分析,观察治疗前后视力、眼压、前房深度、房角的变化及并发症的情况。计量资料采用配对t检验进行分析。

结果：术前视力、眼压、前房深度分别为0.14±0.18,34.5±6.5mmHg,1.51±0.27mm; 术后1wk; 1,6mo视力分别是0.61±0.14,0.61±0.2,0.60±0.151; 术后1wk; 1,6mo眼压分别是13.1±3.7,12.8±3.9,12.9±4.3mmHg; 前房深度为2.49±0.3 1,2.45±0.39,2.46±0.43mm; 术后1wk; 1,6mo的眼压明显低于术前眼压,视力、前房深度、房角变化在手术前后具有显著的差异(P<0.05)。术后不同的时段,各参数之间均无显著的差异。房角镜检查：112眼房角均完全开放。术后浅前房、高眼压率及前房炎症反应等均得到及时有效的治疗。

结论：超声乳化白内障摘除人工晶状体植入联合房角分离术治疗白内障合并闭角型青光眼可明显地提高视力,安全有效、方便快捷、并发症少,可广泛运用。     

白内障超声乳化人工晶状体植入联合房角分离术治疗急性闭角型青光眼合并白内障

目的：观察白内障超声乳化人工晶状体植入联合房角分离术治疗急性闭角型青光眼合并白内障的疗效。

方法：收集2009-10/2014-06急性闭角型青光眼合并白内障40例52眼,手术均采用颞侧透明角膜切口,白内障超声乳化人工晶状体植入联合房角分离术,术后随访6mo。

结果：术后最佳矫正视力较术前显著提高(P<0.01); 患者术后6mo眼压平均为15.76±2.09mmHg,较术前用药前后眼压相比均显著下降(P<0.01); 术后患者房角均较术前增宽,房角粘连关闭象限不同程度开放; 术前前房深度为1.97±0.29mm,术后增加到2.83±0.35mm,差异有显著性(P<0.05); 未发生恶性青光眼、后囊膜破裂等并发症; 所有术眼人工晶状体均在晶状体囊袋内,未出现偏位、夹持。

结论：白内障超声乳化吸除联合房角分离术可有效降低眼压,提高视力,为急性闭角型青光眼同时合并白内障患者安全有效的治疗途径。     

超声乳化白内障吸除联合小梁切除术治疗闭角型青光眼合并白内障

目的：探讨双切口白内障超声乳化吸除人工晶状体植入联合小梁切除术治疗闭角型青光眼合并白内障的临床疗效。方法：回顾分析双切口白内障超声乳化吸除人工晶状体植入联合小梁切除术治疗闭角型青光眼合并白内障患者65例70眼,术后随访3~12mo,观察视力、眼压及并发症的发生。
　　结果：术后患者视力≤0.1者2眼,>0.1~0.3者6眼,0.4~0.8者60眼,≥1.0者2眼,术后眼压在正常范围内(<21mmHg)者69眼,1眼术后出现浅前房,经治疗改善。
　　结论：双切口白内障超声乳化吸除人工晶状体植入联合小梁切除术治疗闭角型青光眼合并白内障手术成功率高,疗效佳,是一种理想的手术方式。     

超声乳化白内障吸除联合小梁切除术治疗闭角型青光眼合并白内障

目的:观察超声乳化白内障吸除人工晶状体植入联合小梁切除术治疗闭角型青光眼合并白内障的临床效果。方法:对闭角型青光眼并白内障36例46眼行超声乳化白内障吸除折叠式人工晶状体植入联合小梁切除手术治疗。术前、术后分别详细记录患者视力、眼压、滤过泡、前房深度、房角及眼底情况。结果:术后随访3mo～2a,43眼(93.5%)视力较术前明显提高,44眼(95.7%)眼压保持在正常范围,术后眼压<21mmHg。35例46眼患者前房深度术前平均为2.1±0.3mm,术后平均3.8±0.4mm,术后所有患者前房深度均加深,术前关闭的前房角也有不同程度的开放。6眼(13.0%)角膜水肿,无角膜内皮失代偿。结论:合并白内障的闭角型青光眼患者行超声乳化白内障吸除联合小梁切除术安全有效,能够有效降低眼压、加深前房、开放房角,提高视力。     

联合手术治疗合并白内障的急性闭角型青光眼疗效观察

目的：分析白内障超声乳化人工晶状体植入联合房角分离术治疗合并白内障的急性闭角型青光眼的临床应用效果。

方法：选取2010-06/2018-09期间我院收治的合并白内障的急性闭角型房角粘连<180°患者40例40眼,根据手术方法不同分为观察组和对照组。观察组采用白内障超声乳化人工晶状体植入联合前房角分离术治疗,对照组采用白内障超声乳化人工晶状体植入术治疗,将两组患者治疗结果进行对比。

结果：术后3、6mo,观察组视力、眼压、前房深度均优于对照组(P<0.05)。随访期间两组均无严重并发症发生。

结论：白内障超声乳化人工晶状体植入联合房角分离术治疗合并白内障的急性闭角型房角粘连<180°的患者临床效果显著。     

白内障超声乳化术治疗闭角型青光眼并白内障

目的:观察白内障超声乳化并人工晶状体植入术及联合小梁切除术治疗闭角型青光眼并白内障的安全性和有效性。 方法:闭角型青光眼合并白内障患者251 例279眼,208眼前房角宽度为NⅠ～NⅡ,单纯施行白内障超声乳化并人工晶状体植入术; 71眼前房角宽度为NⅢ～NⅣ,施行白内障超声乳化并人工晶状体植入联合小梁切除术。 结果:术后随访3mo,单纯超声乳化组208眼眼压均保持在正常范围;超声乳化联合手术组68眼眼压保持在正常范围。术后1wk有3眼眼压仍波动在20～25mmHg,经给予50g/L贝特舒眼液点眼治疗,眼压控制正常。全部病例视力较术前提高,未发生严重并发症。 结论:白内障超声乳化术并人工晶状体植入及联合小梁切除术对闭角型青光眼患者的治疗安全、有效、并发症少。     

慢性闭角型青光眼白内障手术治疗临床探讨

目的 探讨慢性闭角型青光眼合并白内障的手术方法.方法 慢性闭角型青光眼合并白内障共64例（66眼）.其中43例（45眼）施行晶状体超声乳化吸出、人工晶状体植入联合房角分离术,21例（21眼）施行晶状体超声乳化吸出、人工晶状体植入联合小梁切除术.结果 术后视力：晶状体超乳联合房角分离手术组术后视力比术前提高者44眼（97.78%）.晶状体超乳联合小梁切除手术组术后视力比术前提高者18眼（85.72%）.术后眼压：晶状体超乳联合房角分离手术组术后第1天眼压正常;8周后有2眼眼压＞30 mmHg,给予二期行小梁切除术.晶状体超乳联合小梁切除手术组术后第1天19眼（90.48%）眼压正常,有2眼（9.52%）低眼压,4周后均恢复正常.结论 慢性闭角型青光眼合并白内障采用晶状体超声乳化吸出、后房人工晶状体植入联合房角分离术或联合小梁切除术均能有效地提高患者的视力并降低眼压.     

白内障小切口囊外摘除联合小梁切除治疗PACG合并白内障

目的：观察白内障小切口囊外摘除联合小梁切除术治疗原发性急性、慢性闭角型青光眼的疗效。

方法：急性闭角型青光眼合并白内障23例24眼,慢性闭角型青光眼合并白内障11例12眼,进行白内障小切口囊外摘除联合小梁切除术,均一期植入人工晶状体。

结果：术后随访1mo,急性闭角型青光眼组术前平均眼压30.68±7.60mmHg,术后17.83±5.95mmHg,差异有统计学意义(P<0.05); 慢性闭角型青光眼组术前平均眼压29.27±5.55mmHg,术后18.12±1.88mmHg,差异有统计学意义(P<0.05)。术前、术后两组间平均眼压差异无统计学意义。术后眼压控制良好者(6～21mmHg)者26眼(72%),局部使用抗青光眼药物后眼压控制良好者8眼(22%),总体有效控制率94%,眼压不能控制者(22～30mmHg)2眼(6%); 术后视力提高者32眼(89%),没有发生严重并发症。

结论：白内障小切口囊外摘除联合小梁切除术对于原发性闭角型青光眼(PACG)合并白内障的治疗可以有效控制眼压、提高视力,并发症少; 其在控制眼压方面对于原发性急/慢性闭角型青光眼无差异。     

超声乳化吸出联合小梁切除术治疗青光眼合并白内障

目的评价晶状体超声乳化吸出折叠式人工晶状体植入联合小梁切除术的效果和安全性以及手术技术的进步。方法对47例(53眼)青光眼合并白内障手术进行回顾性临床分析。随访12~18个月。手术技术的改进包括抗代谢药物的使用;双切口法;可调节缝线及以穹隆为基底的结膜瓣等4方面。结果53眼中49眼(92.45%)眼压控制在21mmHg以下(1mmHg=0.133kPa),其中28眼(52.83%)在15mmHg以下。眼压由术前平均(25.17±3.70)mmHg降至术后(16.79±2.78)mmHg,(t=21.60,P=0.000);使用抗青光眼药物由术前平均(1.89±0.49)种减少到术后仅8眼(15.09%)需1种。39眼(73.58%)获得≥0.5校正视力,术后视力较术前明显提高(z=-5.845,P<0.001)。术后早期发生纤维素性葡萄膜炎9眼,浅前房2眼,低眼压黄斑水肿2眼,脉络膜脱离1眼。结论超声乳化白内障吸出人工晶状体植入联合小梁切除术可以在降低眼压的同时恢复视力,减少抗青光眼药物的使用。改良的联合手术技术提高了效果和安全性。     

Combined cataract and glaucoma surgery

The management of cataract in glaucoma patients has been continuously changing over the past decade. Extracapsular cataract extraction has been replaced by small-incision phacoemulsification with foldable lenses, and in glaucoma surgery, adjunctive antifibrotic therapy based on risk factors for failure has become standard. Furthermore, new techniques in filtering and nonfiltering surgery have been suggested. The techniques, however, change so fast that well-controlled studies with a follow-up of more than 12 months are increasingly seldom. The purpose of this paper is to review the current literature and to point out some new ideas for the future investigation.     

白内障继发青光眼的超声乳化治疗

目的 研究白内障继发青光眼的超声乳化手术治疗方法的疗效。方法 用白内障超声乳化吸除加人工晶状体植入术治疗术前眼压控制在40mmHg(1mmHg=0.133kPa)以下,房角无广泛粘连的白内障继发青光眼27例(29眼),并观察疗效。结果 手术均取得成功,术后矫正视力,3例(3眼)因视神经及黄斑病变≤0.2,另24例(26眼)术后4周矫正视力≥0.8,术中及术后并发症轻,术后眼压控制良好,除1例需再行巩膜瓣下小梁切除术。结论 超声乳化白内障吸除加人工晶状体植入术是治疗早期白内障继发青光眼的一种有效、安全的方法,但应严格选择病例。     

Steroid induced glaucoma and cataract

Long term use of topical & systemic steroids produce secondary open angle glaucoma similar to chronic simple glaucoma. The increased IOP caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible. In this study, we analysed 25 patients (44 eyes) with steroid induced glaucoma, who reported to us with dimness of vision, haloes and elevated I.O.P. and were using steroids for long duration due to various causes. The behaviour of the I.O.P. due to different steroid preparations, the type of lenticular change, and the management of those cases are discussed in this paper. From our study we conclude that dexamethasone and betamethasone both topical as well as systemic are more potent in producing glaucoma and cataract than medrysone and prednisolone. The condition is reversible without permanent damage when the duration of steroid therapy is short and vice versa.     

青光眼合并白内障的手术选择

目的探讨原发性闭角型青光眼合并白内障的手术选择。方法38例（40眼）原发性闭角型青光眼合并白内障，根据眼压是否易被控制及C值等分别采用不同的手术方式，其中施行晶状体超声乳化人工晶状体植入术25例（27眼）；白内障青光眼联合手术10例（10眼）；分期手术（先行青光眼手术，再行白内障手术）3例（3眼）。术后随访1～12月。结果术后视力均有不同程度提高。单纯白内障组中，24眼眼压控制正常，3眼需在药物治疗下控制正常。10眼联合手术和3眼分次手术眼压均控制正常。角膜水肿5眼，其中单纯白内障组者3眼（11．11％），联合手术组者2眼（20．00％）。术后前房纤维素性渗出2眼均为联合手术组者。结论青光眼合并白内障应根据各项检查结果选择适当的手术方式，才能降低眼压，提高视力，减少术后并发症的发生。     

Management of coincident glaucoma and cataract

Cataract and glaucoma are two very common conditions that frequently are coincident within the same patient. The surgical treatment of the patient with both cataract and glaucoma has changed considerably in the era of small-incision cataract surgery. Additionally, many surgeons are employing antimetabolites routinely in combined phacoemulsification and trabeculectomy. This article reviews the literature as it pertains to combined cataract and glaucoma surgery within the 1-year scanning period. This is not a comprehensive review in that many very important articles are excluded because they were published either before or after the scanning period. The important topics included within this article involve the use of mitomycin C in combined surgery, the comparison of combined phacoemulsification and combined standard extracapsular procedures, long-term results of combined cataract and glaucoma surgery, the survival of filtration blebs after cataract extraction in eyes that had previous trabeculectomy, new techniques of combined surgery including clear corneal cataract extraction combined with trabeculectomy, and the effect of phacoemulsification on intraocular pressure in patients with and without glaucoma.     

Management of coincident glaucoma and cataract

The glaucoma combined procedure continues to evolve and improve. The use of antimetabolites as pharmacologic modulators of wound healing in conjunction with argon laser suture lysis and small-incision phacoemulsification techniques has revolutionized the glaucoma combined procedure. This discussion describes the current trends in the management of coincident glaucoma and cataract. The literature from the past year is reviewed with respect to this important topic. The role of antimetabolites in combined glaucoma surgery, the implications of the pseudoexfoliation syndrome, and the various options available for small pupil phacoemulsification are addressed. The intention is not to provide a comprehensive review of this topic but to discuss current opinion on the various issues that have been addressed in literature during the past year.