上颌尖牙埋伏阻生的外科-正畸联合治疗

目的:探讨尖牙埋伏阻生的外科-正畸联合治疗方法。方法:20例患者28颗上颌埋伏阻生尖牙,先用滑动直丝弓矫治器初步排齐牙列后,再局部间隙扩展,采用外科闭合式助萌技术,暴露埋伏尖牙牙冠,粘贴托槽,再进行正畸牵引导萌。结果:24颗埋伏尖牙均牵引入正常牙列,牙髓、牙周情况正常。有4颗尖牙因横位阻生和根冠成角采用外科拔除。结论:通过外科手术暴露和正畸牵引导萌联合治疗,能有效矫治埋伏阻生尖牙。     

上颌埋伏尖牙的外科—正畸治疗

目的　对上颌埋伏尖牙进行外科—正畸治疗。方法　先用方丝弓固定矫治器进行间隙扩展 ,然后根据上颌埋伏尖牙的位置及与邻牙的关系 ,分析其阻生的病因 ,采用外科翻瓣导萌术 ,暴露埋伏尖牙的牙冠 ,粘贴托槽 ,再选择不同的方向和方法对 12例患者的 14颗上颌埋伏尖牙进行正畸牵引导萌。结果　 11颗埋伏尖牙均已萌出后排齐 ,牙髓和牙周情况正常。结论　只有通过从上颌埋伏尖牙的位置关系 ,分析其阻生的病因 ,选择正确的外科手术暴露和正畸牵引导萌的方法 ,才能有效地矫治上颌埋伏尖牙。     

手术联合正畸导萌埋伏尖牙的临床研究

目的探讨外科联合正畸导荫埋伏尖牙的疗效。方法方丝弓矫治技术先排齐牙列,扩展尖牙缺失处间隙,采用外科翻瓣导萌术,暴露埋伏尖牙的牙冠,粘接舌侧扣,对埋伏尖牙进行正畸牵引导萌。结果12颗埋伏尖牙均被牵引至牙列并排齐,牙髓和牙周情况正常。结论正确的外科手术暴露和正畸牵引导萌,能有效牵引埋伏尖牙至牙列。     

正畸牵引联合牙槽外科矫治上颌尖牙埋伏阻生的临床观察

目的 观察正畸牵引联合牙槽外科手术矫治上颌尖牙埋伏阻生的临床疗效。方法 对30例上颌尖牙埋伏阻生病例,利用正畸牵引联合牙槽外科手术进行矫治。结果 6例埋伏尖牙,经开拓间隙或减数助萌治疗,3～5个月后自然萌出;24例行牙槽外科开窗术配合正畸牵引,8～12个月后萌出。牙髓活力正常,牙龈形态美观,牙周情况良好。结论 正畸牵引联合牙槽外科手术,可快速有效地矫治上颌埋伏阻生尖牙。     

外科翻瓣导萌术结合Edgewise技术治疗上颌埋伏阻生前牙

目的:探讨上颌埋伏阻生前牙的外科、正畸联合治疗方法。方法:32例患者42颗上颌埋伏阻生前牙,先用方丝弓固定矫治器进行间隙扩展,然后根据上颌埋伏牙的位置及与邻牙的关系,分析其阻生的原因,采用外科翻瓣导萌术,暴露埋伏牙的牙冠,粘接托槽,再选择不同的方向和方法对上颌埋伏牙进行正畸牵引导萌。结果:牵引42颗,成功41颗,失败1颗;成功者全部回复到牙列上,整个疗程6～15个月不等。7颗移位阻生牙,除2颗回复到正常位置外,其余5颗均易位排列在牙列上。对埋伏阻生牙的牙髓活力测定结果:4颗牙髓坏死,牙体变色,22颗牙髓活力减低,余均正常。结论:选择良好的适应证、准确的定位、足够的间隙、适当的牵引力,只有通过从上颌埋伏前牙的位置关系,分析其阻生的病因,选择正确的外科手术和正畸牵引导萌的方法,才能有效地矫治上颌埋伏前牙。     

上颌埋伏阻生前牙正畸治疗的临床研究

目的：观察上颌埋伏阻生前牙应用固定正畸方法进行矫治的临床疗效,探讨埋伏阻生前牙有效的治疗方法。方法：对49例58颗上颌前牙埋伏阻生病例,应用固定正畸进行矫治,结合牙槽外科开窗术,对埋伏牙进行牵引。其中20颗进行开拓间隙使之自然萌出,38颗进行开窗封闭式牵引导萌矫治。结果：55颗阻生牙矫治后牙髓活力正常、未见埋伏牙及邻牙牙根吸收、牙周组织正常。开窗封闭式牵引导萌有3颗牙治疗失败,总体成功率94.8%。结论：应用固定正畸技术开拓间隙或结合牙槽外科开窗术导萌埋伏阻生牙,可有效保存上颌埋伏阻生前牙。     

上颌埋伏阻生中切牙的治疗

上颌埋伏阻生中切牙的治疗方法主要有减阻助萌法、外科手术暴露联合正畸牵引法和拔除法等。减阻助萌法仅适用于正位埋伏且尚具有萌出潜力的牙齿,其预后一般较好。外科手术暴露联合正畸牵引法是目前临床上最常采用治疗埋伏牙的方法,外科手术暴露方法主要有开放式导萌法和封闭式导萌法。其中,封闭式导萌法的效果更好。正畸牵引中支抗的设计、牵引的位置和方向以及牵引的力值大小最为重要。拔除法和其他的治疗方法在临床上较少采用,主要是用来治疗弯根埋伏牙。     

外科导萌联合正畸治疗上颌埋伏尖牙的疗效观察

［摘要］ 目的 观察通过正畸的方法牵引上颌埋伏尖牙的治疗效果。方法 对17例患者的上颌埋伏尖牙经外科手术开窗后,粘正畸附件,用正畸方法将其牵引并移到牙弓的正常位置。结果 16例埋伏尖牙均被牵引入牙弓内的正常位置,牙龈附着良好,牙髓活力正常,未见邻牙牙根吸收及损伤。结论 外科导萌与正畸联合治疗是恢复上颌埋伏尖牙正常位置及功能的有效方法。     

上颌埋伏尖牙非手术助萌的正畸治疗

[摘要] 目的 探讨上颌埋伏尖牙非手术助萌正畸治疗的适应证及其临床效果。方法 选取10～15岁上颌埋伏尖牙患者20例,应用螺旋CT三维重建技术对其进行诊断,明确埋伏尖牙颌骨内位置、方向及牙根发育情况,选取适合病例12例通过正畸手段为埋伏尖牙开辟间隙,等待其自行萌出;8例采用外科翻瓣导萌术牵引导萌。结果 12例非手术助萌患者,正畸拓展足够间隙后经3～10个月上颌埋伏尖牙均自行萌出至正常位置,牙周附着健康;8例外科手术导萌患者,上颌埋伏尖牙正畸牵引到位后均有不同程度的牙周附着丧失,影响龈缘美观。结论采用螺旋CT三维重建技术可以立体直观的提供埋伏尖牙的信息,为临床医师明确诊断及制定治疗方案提供依据,减少手术适应证,使用非手术助萌的方法可使上颌埋伏尖牙自行萌出,避免手术创伤痛苦,萌出后牙周附着好。     

上颌埋伏尖牙外科正畸联合治疗

目的：探讨上颌埋伏尖牙通过外科导萌和正畸联合治疗的临床效果。方法：对28颗上颌埋伏尖牙利用固定矫治器为其提供间隙，通过翻瓣去骨显露埋伏牙牙冠，再牵引入牙列。结果：26颗上颌埋伏尖牙排入牙列。结论：外科正畸联合方法是可靠的上颌埋伏尖牙治疗方法。     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31–82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL‐QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non‐dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non‐dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non‐dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health.     

拔牙位点保存用复合温敏凝胶的构建及体外表征

目的:制备多壁碳纳米管/羟基磷灰石/壳聚糖复合温敏凝胶,探讨其作为拔牙位点保存材料的理化性能。方法:采用原位沉积方法制备多壁碳纳米管/羟基磷灰石(MWNT/ HA简称HAC)复合无机材料,将其分散至壳聚糖温敏凝胶中,制备壳聚糖/多壁碳纳米管/羟基磷灰石(CS /MWNT/HA简称CS/HAC)复合温敏凝胶,以成胶时间、孔径、孔隙率、机械强度及降解性能为指标优化配方设计,并表征复合温敏凝胶的微观形貌及理化性能。结果:以10 g/L的HAC作为补强成分加入到壳聚糖溶液中,能够在不影响成胶并保证一定孔隙率(84%)的前提下,提高材料的机械性能(抗压强度0.441 MPa),所获复合温敏凝胶具有适宜的临床操作时间(12 min),并具有可控的降解速率。结论:负载HAC的复合温敏凝胶具有良好的成型性,并具有较好的机械性能,在拔牙位点保存领域具有良好的应用前景。     

替牙期骨性Ⅲ类错牙合患者颞下颌关节特征的锥形束CT研究

目的:采用锥形束CT(CBCT)研究替牙期骨性Ⅲ类错牙合患者颞下颌关节的影像学特征,探讨Ⅲ类功能状态下,颞下颌关节的生长、改建机制。方法:从就诊于昆明医科大学附属口腔医院正畸科的患者中选取符合纳入标准的替牙期骨性Ⅲ类错牙合患者及骨性Ⅰ类错牙合患者各20名,使用NNT viewer 5.3图像处理软件进行三维重建及线距和角度的测量,并进行统计学分析。结果:替牙期骨性Ⅲ类错牙合患者组和替牙期骨性Ⅰ类错牙合患者组对比结果为:矢状面双侧关节前间隙偏小、双侧关节上间隙偏小、双侧关节结节斜度偏小;冠状面双侧关节内间隙偏小,双侧关节上间隙偏小,双侧关节外间隙偏小,右侧髁状突角度偏小;横截面右侧髁状突前后径偏小。结论:替牙期骨性Ⅲ类错牙合患者颞下颌关节发育不充分,呈现髁状突,关节窝深度,关节结节斜度;冠状面关节内、外间隙均较小的特征。骨性Ⅲ类错牙合患者髁状突在关节窝中处于前置近关节窝顶位置。骨性Ⅲ类错牙合患者颞下颌关节影像学特征与其功能状态相适应。