Minimally invasive coronary artery bypass grafting via a small thoracotomy versus off-pump: a case-matched study

Objective: The minimally invasive coronary artery bypass grafting (MICS CABG) operation performed via a small thoracotomy has not previously been examined in a direct comparison to sternotomy off-pump coronary artery bypass grafting (OPCAB). Methods: We matched, according to age, gender, left ventricular function, and median number of distal anastomoses, 150 patients who underwent MICS CABG via small left thoracotomy, and 150 patients who received sternotomy OPCAB. All operations were performed by the same surgeon. Results: There was no perioperative mortality (0/300). In the MICS CABG group, pump assistance was used in 28/150 (19%) patients, and conversion to sternotomy occurred in 10/150 (6.7%) patients. In the OPCAB group, conversion to on-pump occurred in 3/150 (2.0%) patients. There were four (2.7%) reoperations for bleeding and one (0.7%) for anastomotic revision in each group. The median hospital length of stay was 5 days for MICS CABG (average 5.4), and 6 days for OPCAB (average 7.2) (P = 0.02). New-onset atrial fibrillation occurred in 35 (23%) MICS CABG patients and in 42 (28%) OPCAB patients (P = 0.3). No wound infection occurred with MICS CABG versus six (4.0%) with OPCAB (P = 0.03). A self-limiting left pleural effusion developed in 22 (15%) MICS CABG patients and in six (4.0%) OPCAB patients (P = 0.002). The median time to return to full physical activity was 12 days in MICS CABG patients versus >5 weeks in OPCAB patients (P < 0.001). Conclusions: MICS CABG is a valuable alternative for patients in need of multivessel CABG. The operation appears at least as safe as OPCAB, and associated with shorter hospital length of stay, less wound infections, and faster postoperative recovery than OPCAB.     

微创冠状动脉旁路移植术处理前降支病变的围术期结果

目的研究胸腔镜辅助下经左胸小切口微创直视下冠状动脉旁路移植术(minimally invasive direct coronary artery bypass grafting,MIDCAB)处理前降支病变的围术期结果及其安全性。方法回顾性分析2014年5月至2018年10月在我院接受MIDCAB 92例患者的临床资料,其中男72例(78.26%),年龄42~78(61.29±7.48)岁,女20例(21.74%),年龄30~80(61.30±12.26)岁。分析围术期并发症发生率、血制品使用情况、左心功能变化情况、呼吸机使用时间、住ICU时间及住院时间等指标。结果2例(2.17%)患者中转正中开胸手术,5例(5.43%)术中输入血液制品,2例(2.17%)二次开胸止血,4例(4.34%)术后低氧血症,1例(1.08%)再次气管插管。呼吸机使用时间3~227(22.35±35.39)h,住ICU时间16~777(78.85±108.62)h,术后住院时间2~36(8.86±6.05)d。住院死亡1例(1.08%)。结论MIDCAB处理前降支病变具有较好的围术期结果,尤其适用于孤立性前降支病变,可缩短术后呼吸机使用时间、减少血液制品使用、缩短住ICU时间及住院时间。     

Reoperative coronary artery bypass grafting using a minimally invasive direct coronary artery bypass procedure

OBJECTIVE: Reoperative coronary artery bypass grafting with cardiopulmonary bypass tends to cause a higher mortality and morbidity than the primary operation. The purpose of this study was to discuss the effectiveness and safety of a minimally invasive coronary artery bypass procedure for patients who had previously undergone coronary artery bypass surgery. METHODS: We performed redo single coronary artery bypass grafting to the left anterior descending coronary artery in 9 patients and to the right coronary artery in 3 patients using minimally invasive cardiac surgery. The graft to the left anterior descending coronary artery was taken from the left internal thoracic artery in 5 patients, the right gastroepiploic artery in 3 patients, and from the saphenous vein in the other 1 patient. The graft to the right coronary artery was from the right gastroepiploic artery in all 3 patients. RESULTS: All grafts were patent. There was no major postoperative complication and no surgical or hospital death except one late death. CONCLUSIONS: In selected patients, we could safely and completely perform coronary artery bypass re-grafting to the left descending coronary artery or right coronary artery using a minimally invasive operation.     

微创冠状动脉旁路术33例中期结果报告

目的总结33例经左胸小切口微创冠状动脉旁路术(minimally invasive direct coronary artery bypass,MIDCAB)的中期疗效. 方法 2000年11月～2003年4月共行MIDCAB 33例,单纯MIDCAB 29例,杂交技术4例.25例采用经典MIDCAB,4例胸腔镜辅助,4例AESOP机器人辅助. 结果全组无手术死亡,无手术并发症.呼吸机脱机时间(7.5±1.9) h,引流量(274±197)ml,输血率9.1%(3/33),术后住院(6.9±1.7)d.随访33例,时间(24.3±5.7)个月,无远期死亡,心绞痛复发率9.1%(3/33).术后再次冠状动脉造影4例,1例吻合口狭窄50%,余3例前降支与左乳内动脉吻合口通畅.术后导管再次血管化2例(6.1%). 结论 MIDCAB术中期效果满意.     

微创冠状动脉旁路移植手术33例报告

目的探讨微创冠状动脉旁路移植手术(minimally invasive direct coronary artery bypass graft,MIDCABG)的可靠性及安全性. 方法 2001年3月～2003年9月,我院在全麻、非体外循环、心脏不停跳下进行了33例单支MIDCABG.14例采用左前外侧小切口,19例采用胸骨下段正中切口.31例行左乳内动脉至前降支旁路移植,1例使用大隐静脉行主动脉根部至前降支旁路移植,1例行胃网膜右动脉至后降支旁路移植. 结果全组无手术死亡.术中出血量(163±120)ml,术后引流量(193±169)ml,术后拔管时间(6.4±5.5)h,ICU时间(17.8±4.4)h.随访(14.7±7.4)月,无死亡. 结论 MIDCABG安全可靠,具有创伤小、出血量少、并发症少的优点.     

胸部小切口冠状动脉搭桥术

目的 评价胸部小切口冠状动脉搭桥术的临床疗效。方法 采用左胸部小切口取左乳内动脉,左心脏跳动下行冠状动脉搭桥术141例。其中前降支单支病变83例,多支病变58例。合并高危因素者58例,经行皮冠状动脉腔内成型术（PTCA）术后45例,冠状动脉搭桥术后10例。结果 全组均完成手术,其中左乳内动脉搭至前降支139例,第一对角支2例。无围手术期死亡。术后行2次冠状动脉搭桥术1例,PTCA21例。冠状动脉造影显示血管桥通畅率98．5％。结论 胸部小切口冠状动脉搭桥术主要适用于前降支的再血管化。该手术安全可靠,疗效优良,在合并高危因素或常规搭桥手术效果不满意者中应用更佳。     

左胸前外侧小切口不停跳冠状动脉旁路移植术26例

目的探讨左胸前外侧小切口不停跳冠状动脉旁路移植术的效果.方法26例单支或2支血管病变经左胸前外侧小切口进胸,其中14例直视下游离乳内动脉,12例在胸腔镜辅助下游离,肝素化后切开心包,显露病变的靶血管,心脏跳动下行冠状动脉旁路移植术.结果26例手术顺利完成,22例旁路移植1支,4例旁路移植2支(1例行序贯吻合,3例桡动脉与乳内动脉行"Y"形吻合).术后无死亡及严重并发症.26例随访3个月～3年,平均16.8月,无心绞痛复发,心功能Ⅰ级18例,Ⅱ级8例.结论左前外侧小切口不停跳冠状动脉旁路移植术主要适用于前降支单支病变者,对于合并高危因素,不宜行常规冠状动脉旁路移植的多支血管病变病人亦适用.     

Minimally invasive coronary artery bypass grafting for the left anterior descending coronary artery.

OBJECTIVE: A single surgeon conducted One hundred and twelve patients underwent minimally invasive direct coronary artery bypass grafting for the left anterior descending coronary artery 112 patients at Yamato Seiwa Hospital from September 1996 until August 1999. METHODS: All procedures were performed via left anterior short thoracotomy using a stabilizer during graft anastomosis. RESULTS: No operative deaths occurred but 3 patients died while hospitalized due to noncardiac events. Graft occlusion was seen in 3 patients early postoperatively. Other angiography graft failure such as stenosis was seen in 11 patients. Occlusive lesions of other coronary arteries occurred in 77 patients (69%) and 53 patients underwent percutaneous transluminal coronary angioplasty the pre/postoperatively for those lesions. CONCLUSIONS: These results suggest that minimally invasive direct coronary artery bypass grafting is seen by cardiologists as a reasonable form of revascularization in conditioned patients having left anterior descending artery lesion, and that minimally invasive direct coronary artery bypass grafting has a spectrum of candidates different from that of conventional surgical revascularization for the coronary artery.     

胸骨下段正中小切口在冠状动脉旁路移植术中的应用

目的总结162例胸骨正中下段小切口行冠状动脉旁路移植手术的经验. 方法 1998年4月～2003年6月,经胸骨下段正中小切口行冠状动脉旁路移植手术162例,包括体外循环下冠状动脉旁路移植术(coronary artery bypass grafting, CABG)77例,CABG联合心内手术13例,非体外循环CABG(off-pump coronary artery bypass grafting, OPCABG)72例. 结果手术死亡1例(0.6%),再手术1例(0.6%),术后并发症9例(5.6%).体外循环手术的主动脉阻断、体外循环及手术时间分别为(74.8±23.1) min、(113.6±31.3) min及(255.5±54.5) min.非体外循环手术时间(195.6±50.6) min.吻合口数目1～5个,(2.4±0.7) 个.术后气管插管时间0～364 h,中位数11 h;恢复室时间1～28 d,中位数3 d;术后住院5～60 d,中位数10 d.胸腔引流量(607.2±443.0) ml,按体重计算为(8.6±6.0) ml/kg.38例输血,输血量(1 161.3±741.2) ml. 结论胸骨正中下段小切口行冠状动脉旁路移植手术创伤小,安全可靠;皮肤切口小;无须特殊器械,操作简单,可获得冠状动脉多支病变充分再血管化的效果,可同时进行其他心内手术.     

Minimally invasive coronary artery bypass grafting for myocardial muscle bridging

Myocardial bridging is a congenital anomaly of the left anterior descending coronary artery (LAD), which is associated with myocardial ischemia and infarction, cardiac arrhythmias, and sudden cardiac death. Two cases are reported of symptomatic myocardial bridging refractory to medical management treated by minimally invasive coronary artery bypass grafting without cardiopulmonary bypass. We conclude that minimally invasive coronary artery bypass techniques are appropriate alternatives to endovascular stent placement, muscle bridge division, or aortocoronary grafting with cardiopulmonary bypass for the management of symptomatic myocardial bridging.     

经左胸前外侧小切口冠状动脉旁路移植术

目的 评价经左胸前外侧小切口冠状动脉旁路移植术的临床疗效及远期随访结果.方法 2002年1月至2006年10月,38例单支或多支冠状动脉病变患者经左胸前外侧小切口进胸,直视下或胸腔镜辅助下,完成非体外循环冠状动脉旁路移植术.其中男性25例.女性13例;年龄38～78岁,平均(63.3±11.1)岁.结果 38例手术均顺利完成.20例行单纯旁路移植1支;10例先行支架植入,后行胸廓内动脉至前降支端侧吻合,其中2例行胸廓内动脉与第一对角支、前降支序贯吻合;8例行旁路移植2支,其中3例为序贯吻合,5例应用桡动脉行"Y"形吻合.术后无死亡及严重并发症.37例患者获得26～82个月随访,平均(53.2±28.5)个月;无晚期死亡,无再发心肌梗死.心功能Ⅰ级26例,Ⅱ级12例.3例心绞痛复发,2例经药物控制后症状缓解,1例经造影证实吻合口狭窄于术后2年行支架植入.结论 左前外侧小切口非体外循环冠状动脉旁路移植术具有较低的病死率和心脏不良事件发生率,远期结果良好.     

应用Port-Access系统行微创冠状动脉旁路移植术21例体会

目的　介绍应用Port-Access系统进行微创冠状动脉旁路移植术的体会。　方法　采用左胸小切口 (6～ 7)cm ,经股静脉插静脉管 ,经升主动脉或股动脉插动脉管 ,主动脉内球囊阻断的方法 ,行微创冠状动脉旁路移植术。　结果　本组 2 1例无手术死亡 ,无重大并发症。　结论　应用Port-Access系统进行微创冠脉搭桥手术是一种安全可靠的手术方法 ,可以避免胸骨切开 ,减轻疼痛 ,利于患者后恢复。     

经左前外侧小切口不停跳冠状动脉旁路移植术治疗多支血管病变的临床研究

目的 分析经左前外侧小切口行不停跳冠状动脉旁路移植术(CABG)治疗多支血管病变冠状动脉粥样硬化性心脏病(冠心病)的安全性和随访结果.方法 回顾性分析2018年1月至2020年3月在我院行左前外侧小切口不停跳CABG 30例多支血管病变冠心病患者的临床资料,其中男18例、女12例,平均年龄(61.3±7.5)岁;三支血...     

Perioperative myocardial infarction in patients undergoing off-pump coronary artery bypass grafting

Two patients in whom myocardial infarction in the inferior wall occurred after off-pump coronary artery bypass grafing (OPCAB) are described. In both patients, the right coronary artery had no critical lesion and was not grafted. There was no ischemic episode during operation. Coronary artery spasms and/or intracoronary thrombus formation may have been causes of these events. To our knowledge, this is the first report on perioperative myocardial infarction in OPCAB.     

Anaesthesia for off-pump coronary artery bypass grafting

Achieving surgical revascularization of the heart, while avoiding the insult of cardiopulmonary bypass, is particularly desirable in specific high-risk patient groups. The relatively recent advances in surgical technique allowing high-quality grafting without mechanical arrest have led to an increase in popularity of off-pump coronary artery bypass surgery. Nonetheless, operating on the beating heart, manipulating it and purposely inducing ischaemia, invariably has significant haemodynamic consequences which must be carefully yet aggressively managed. To compound the situation, the intraoperative monitoring typically employed to evaluate cardiac function, such as electrocardiography and echocardiography, are of limited efficacy at crucial moments in the procedure. It is therefore essential that the anaesthetist is able to assimilate information from a multitude of sources in order to safely navigate the patient through a period of continually changing cardiovascular stress.     

Anaesthesia for off-pump coronary artery bypass grafting

Achieving surgical revascularization of the heart, while avoiding the insult of cardiopulmonary bypass, is particularly desirable in specific high-risk patient groups. The relatively recent advances in surgical technique allowing high-quality grafting without mechanical arrest have led to an increase in popularity of off-pump coronary artery bypass surgery. Nonetheless, operating on the beating heart, manipulating it and purposely inducing ischaemia, invariably has significant haemodynamic consequences which must be carefully yet aggressively managed. To compound the situation, the intraoperative monitoring typically employed to evaluate cardiac function, such as electrocardiography and echocardiography, are of limited efficacy at crucial moments in the procedure. It is therefore essential that the anaesthetist is able to assimilate information from a multitude of sources in order to safely navigate the patient through a period of continually changing cardiovascular stress.     

Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

Objectives. Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. Design. We retrospectively analysed the in-hospital data of all patients (n?=?384) undergoing MIDCAB at our department in years 2006-2016. Subsequently, the data were enriched by long-term outcomes from national registries. Results. There were 96 women in our group (25%). Females were significantly older (67.1 vs 63.8 years; p?p?p?=?.02), and also the need for blood transfusion (19.8% vs 10.4%; p?=?.02) and wound complications (15.6% vs 2.4%; p?p?p?p?=?.26), long-term mortality (p?=?.73), and the risk of coronary intervention post-operatively (p?=?.16) were the same in both sexes. Higher incidence of cardiac cause of death in women was observed from long-term aspect (69.6% vs 38.7%; p?=?.01). However, after adjustment it lost its significance. Conclusions. Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.     

Minimally invasive surgery for lung cancer with coronary artery disease

We report a 69-year-old woman with lung cancer and severe stenosis in the left anterior descending coronary artery. To perform a curative operation for the lung cancer without myocardial infarction, minimally invasive direct coronary artery bypass and left lower lobectomy with video-endoscopic assistance were performed simultaneously. There was no major complication, and she was discharged at 14 days after the operation. This procedure may be useful and safe for patients with lung cancer and coronary artery disease.     

左心室功能明显减退患者的冠状动脉旁路术

目的 探讨左心室功能明显减退患者的冠状动脉旁路移植术(CABG)的外科治疗效果。方法 回顾分析2000年12月至2002年12月对心肌梗死或长期慢性心肌缺血造成心室功能明显减退的45例冠心病患者进行CABG的相关资料。结果 42例联合应用左乳内动脉与前降支吻合。人均旁路移植3.3(1～5)支,无手术死亡。术后随访2～23个月,LVEF21.3％～65％,平均(42.7±5.9)％,与术前相比提高9％～24％(P<0.05);LVEDD55.2～64.6 mm,平均(54.7±3.8)mm。与术前相比,无明显变化(P>0.05);心绞痛完全消失39例,活动耐力增加。随访期间死亡2例。结论 左心室功能明显减退的冠心病患者,CABG手术成功率和近期效果满意,生活质量明显提高。术前合理选择病例、术中充分的再血管化和良好的围手术期处理是手术成功的关键。