面部痤疮患者两种生活质量量表的考评

目的了解Cardiff痤疮伤残指数(CADI)和面部痤疮特异性生活质量调查问卷(Qol-acne)两种痤疮量表在国内临床的适用性。方法在知情同意的前提下,应用两量表对66例面部痤疮患者进行生存质量的调查,并分析两量表的信度、效度,并对两量表的得分进行相关分析。结果两量表的信度、效度均较好。两量表得分呈负相关(γ=-0.854,P0.001),即CADI得分越高Qol-acne得分越低。结论两量表均具有较好的信度及效度,能作为我国面部痤疮患者生活质量的测评工具。临床医师可以根据实际情况选择合适的量表对面部痤疮患者进行生活质量的评估。     

中国银屑病患者生活质量量表的编制与考评

目的:编制银屑病患者生活质量量表(psoriasis quality of life scale,PQOLS),并验证该量表信度和效度。方法:根据WHO对生活质量的定义提出理论框架,通过文献回顾和专家咨询的方式编制PQOLS测试版。然后采用初始量表测定银屑病患者的生活质量,根据结果对条目筛选,形成PQOLS的正式版。结果:通过文献回顾和专家咨询建立包含40个条目的备选条目池。通过条目筛选,最终形成了含22个条目的PQOLS,包括疾病、心理、生理、社会4个维度。对136例患者进行测试结果表明:量表各维度及整个量表的Cronbachα均0.8,Sperman-Brown系数均0.7;因子分析发现单因素能够代表量表的大多数因子;PQOLS与皮肤病生活质量指数(DLQI)的Pearson相关系数为0.821;PQOLS总分与银屑病皮损面积和严重程度指数(PASI)值的相关系数为0.506,生活质量与病情严重度呈显著负相关。结论:编制的PQOLS具有较好的信度、效度,适用于银屑病患者生活质量的测评。     

痤疮患者相关知识问卷的信效度研究

目的研究能够客观评价痤疮患者相关知识的问卷,并进行信效度检验。方法通过回顾相关文献回顾、半结构化访谈、专家访谈和专家评议法,形成初始问卷。选取403例痤疮患者进行调查。对问卷信效度进行评价,形成问卷终稿。结果最终形成的痤疮相关知识问卷包括5个维度、24个条目。通过探索性因子分析提取5个公因子。累计方差贡献率为53.907%,问卷内容效度为0.961,Cronbach’sα系数为0.829,重测信度0.897。结论该问卷具有良好的信效度,可作为评价痤疮患者痤疮相关知识了解程度的工具。     

患者健康问卷抑郁量表9在痤疮患者中的信度和效度检验

【摘要】 目的 检验患者健康问卷抑郁量表9（PHQ?9）在痤疮患者中的信度和效度。方法 2017年1月至2018年6月在西南医科大学附属医院门诊收集痤疮患者300例,应用PHQ?9及汉密顿抑郁量表（HAMD）对患者进行问卷调查并记录完成时间,采用美国《精神障碍诊断与统计手册（第4版）》（DSM?Ⅳ）临床定式访谈（SCID）作为抑郁“金标准”进行评定。采用Cronbach′s α系数和1周后重测信度对PHQ?9进行信度分析;效度分析采用因子分析、Spearman相关分析和受试者工作特征曲线（ROC曲线）,并分析PHQ?9在不同分组人群中的筛查效度。结果 共258例痤疮患者完成全部问卷,47例符合抑郁障碍诊断标准。PHQ?9诊断抑郁最佳划界分为9分,此时灵敏度为95.7%,特异度为88.6%,ROC曲线下面积为0.973（95% CI：0.956 ~ 0.990）,在不同分组人群中,ROC曲线下面积最低0.886,最高0.955。效度分析显示,PHQ?9总分与HAMD总分的相关系数为0.766,Kappa值为0.530。因子分析共获得2个公因子,分别为认知-情感因子、躯体症状因子,累计方差贡献率为65.52%。信度分析显示,PHQ?9 Cronbach′s α系数为0.851,各条目与量表总分的相关系数为0.550 ~ 0.709,各条目间的相关系数为0.224 ~ 0.654,重测信度为0.824。完成每份PHQ?9的时间为（4.9 ± 1.2） min,完成HAMD的时间为（44.2 ± 5.9） min,差异有统计学意义（t = 108.787,P < 0.001）。结论 PHQ?9应用于痤疮患者具有良好的信度和效度,可用于对痤疮伴抑郁患者初筛,该量表较HAMD具有明显时间及人力优势,更便于在临床中实施。     

痤疮患者生活质量调查

采用DLQI调查问卷,对112例门诊痤疮患者分别于就诊时和治疗后1个月进行调查,着重研究痤疮患者治疗前、后的生活质量的变化.结果:治疗后随着临床病情的改善,DLQI评分显著下降.DLQI可作为判断痤疮病情及疗效的新指标.     

儿童皮肤病生活质量指数中文版的信度、效度评价

目的评估儿童皮肤病生活质量指数(CDLQI)中文版的信度和效度。方法对广东省中医院151名儿童皮肤病患者进行CDLQI中文版的测试。结果重测信度,计算组内相关系数(ICC)为0.820;Gutt-man分半信度为0.814;Cronbach′sα系数为0.816。各条目得分与其维度得分之间相关系数r均在0.540以上;各维度间的相关系数波动在0.232~0.452;除日常生活领域,各维度与总分的相关系数均在0.60以上。以主成分分析法进行因素萃取,并以Varimax法进行因素转轴,共萃取累计解释变异量大于83.09%的因素。皮肤病患者与其他疾病及健康者CDLQI分值的分布差异有统计学意义(Z=-7.207,-7.164;P=0.000)。结论 CDLQI中文版具有比较好的信度和效度,可在临床研究中将其用于儿童皮肤病生活质量的评估。     

女性玫瑰痤疮患者生活质量调查分析

目的:调查玫瑰痤疮对女性患者生活质量的影响。方法:应用皮肤病生活质量指数(DLQI)调查表和Beck抑郁自评量表(BDI)对123例女性玫瑰痤疮患者进行问卷调查,并收集患者人口统计学基本信息,评估疾病亚型与严重程度。结果:DLQI评分为10.46±6.444;BDI评分提示存在严重抑郁症状的占5.69;单因素方差分析结果提示婚姻情况是重要影响因素;相关性分析结果显示DLQI评分、BDI评分、疾病严重程度三者之间呈正相关。结论:玫瑰痤疮对女性患者的生活质量有明显影响。患者易产生抑郁情绪,且这种影响与疾病的严重程度呈正相关,对已婚女性的影响大于未婚女性。因此对于玫瑰痤疮患者的治疗不仅限于药物治疗,同时要及早进行心理疏导。     

病耻感量表在男性不育症患者中的信效度检验

目的 检验病耻感量表在我国男性不育症患者中的信效度。方法 采用方便取样法,选取2021年12月15日至2022年2月15日在北京市某三甲医院生殖医学中心诊治的338例男性不育症患者作为研究对象。采用基本情况调查表、修订后的病耻感量表及生育生活质量量表进行研究调查。结果 本研究最终形成了包含4个公因子和22个条目的病耻感量表。修订后量表总的Cronbach′s α系数为0.974,折半信度为0.924。方差累计贡献率为78.9%,量表结构效度、聚敛效度、组合信度与区分效度经检验结果均较好,且与生育生活质量有较好的效标关联效度。结论 修订后的病耻感量表信效度良好,可用于我国男性不育症患者病耻感的评估。     

痤疮及相关因素对患者生活质量的影响

新的医学模式提倡临床医生在治疗寻常痤疮患者时,不仅要考虑痤疮分型及临床严重程度,还要考虑患者生活质量受到的影响.近年来,应用不同量表为工具的调查研究均表明,痤疮对患者生活质量有较大的影响,但其对不同年龄、性别患者的影响评价不一.提示专科医生有必要对患者生活质量所受到的影响进行个体化评估,进而选择最佳的治疗方案.     

对痤疮患者生活质量影响因素的分析

目的:了解痤疮患者生活质量及其影响因素。方法:采用自制生活质量调查问卷,对345例痤疮患者进行调查。结果:痤疮患者生活质量降低。多因素Logistic回归分析表明:自我感知和情感功能同性别、家庭情况、痤疮轻重分级和学生与否相关性密切;社会功能同长期居住地、痤疮轻重分级和学生与否相关性密切。结论:针对上述影响因素,临床医师适当实施心理干预措施和健康教育,有助于提高痤疮患者的生活质量。     

Validation of the Dermatology Life Quality Index among patients with podoconiosis in southern Ethiopia

Background Podoconiosis is a geochemical elephantiasis common among subsistence farmers in Ethiopia. It is completely preventable but, untreated, leads to considerable physical disability, social stigma and economic disadvantage. Quality of life has to date not been assessed among patients with podoconiosis. Objectives We aimed to assess the feasibility, internal consistency and concurrent validity of an Amharic translation of the Cardiff Dermatology Life Quality Index (DLQI) among patients with podoconiosis in southern Ethiopia. Methods We performed a comparative cross‐sectional study among 74 new patients and 74 patients treated for at least 3 months at outreach clinics of the Mossy Foot Treatment and Prevention Association, a nongovernment organization providing services for more than 30 000 patients annually in southern Ethiopia. Results The DLQI was quick and simple to use, taking on average 4 min to administer. It distinguished successfully between new and treated patients (median scores 13 vs. 3, P < 0·001). The inter‐item correlation averaged 0·44, and Cronbach’s alpha was 0·90, indicating high internal consistency. The mean DLQI score for all patients was 8·42, and the highest score was for item 2 (feeling self‐conscious). The item with the highest score among new patients was item 1 (pain), while that among treated patients was item 4 (clothes choice). Conclusions The Amharic DLQI appears feasible, reliable and valid among patients with podoconiosis in southern Ethiopia. The DLQI will play an important role in assessing the physical and social interventions available locally and in guiding the roll‐out of these interventions to much larger groups of patients throughout Ethiopia.     

Anxiety Sensitivity and Quality of Life in Patients with Acne

BackgroundAnxiety sensitivity (AS) is a continuous fundamental fear and defined as extreme fear of anxiety sensations and symptoms. High AS can cause tendency to anxiety disorders. There are many studies evaluating the anxiety in patients with acne; however, AS has not been investigated.ObjectiveWe aimed to investigate AS in patients with acne.MethodsTwo hundred and fourteen acne patients and 117 healthy control subjects, aged older than 16 years were enrolled in the study. Severity of acne was evaluated by Global Acne Grading System. The acne patients and healthy controls were asked to complete the anxiety sensitivity index-3 (ASI-3), the Beck anxiety inventory (BAI) and the Turkish version of acne quality of life index.ResultsAnxiety and AS levels in acne patients were significantly higher than healthy controls (p<0.001). Quality of life was impaired in acne patients. Quality of life was negatively correlated with anxiety and AS levels in acne patients (p=0.014, p=0.019, respectively). There was no correlation between quality of life and disease severity (p=0.556) and also there was no correlation between psychiatric scale scores (ASI-3, BAI) and disease severity (p=0.147, p=0.871, respectively).ConclusionTo our knowledge, our study is the first to report that AS is high in acne patients. Clinically, our results suggest that there might be a relationship between AS and acne. We conclude that further studies are needed in order to clarify the relationship between acne and AS and to investigate the efficacy of cognitive behavioral treatments in acne patients.     

Quality of life and acne in Scottish adolescent schoolchildren: use of the Children''s Dermatology Life Quality Index© (CDLQI) and the Cardiff Acne Disability Index© (CADI)

BACKGROUND: Acne vulgaris is known to adversely affect all aspects of quality of life. However, although acne is thought to occur in the majority of adolescents, there are few data currently available on the impact of acne in this age group. OBJECTIVES: Measurement of the impairment of health-related quality of life (HRQoL) in teenage Scottish schoolchildren in a comparative study using two HRQoL questionnaires. A secondary objective was to collect data on the use and perceived efficacy of medical and over-the-counter (OTC) preparations. STUDY DESIGN: An anonymous cross-sectional survey of 200 adolescent (15-18 years) Dundee schoolchildren was conducted by means of two self-reported questionnaires: the Children's Dermatology Life Quality Index (CDLQI) and the Cardiff Acne Disability Index (CADI). Data on demographics and therapeutic modalities and their perceived efficacy were also collected. ANALYSIS: Statistical analysis was performed using the package Stata 7.0. RESULTS: Self-reported acne was present in 83% of teenagers (147/178), with similar sex distribution (54% male, 46% female). The overall mean CDLQI score (max. 30) was low 1.7 {6% impairment} (CI -1 to 0), range 0-19. Nine pupils scored between 5 and 9 {17-30% impairment} suggesting moderate HRQoL impairment and three scored > 10 {> 33% impairment} indicating severe impairment. The overall mean CADI score (max. 15) of 1.9 {13% impairment}, CI 0 to 1 (range 0-15) was also low, but 12 pupils scored between 5 and 9 {33-60% impairment}, one scoring 10 + {> 67% impairment} and one scoring the maximum, 15 {100% impairment}. There was no significant difference in mean scores between the sexes in either questionnaire (P = 0.5). There was good correlation between the results from the two questionnaires (Spearman's rho = 0.62). Three-quarters (75%) had used OTC products, of which only a third (33%) felt they helped 'a lot'. Fifteen per cent were receiving prescribed treatment from their doctors of which 66% found it helpful. CONCLUSIONS: Self-reported acne occurred in 83% (147/178) of the Scottish teenagers involved in this study, which confirms previous reports of a high prevalence of acne in teenagers. Cross-validation of the CLDQI and CADI demonstrated good correlation and both scales were easy to administer and identified 11% (16/147) of teenagers who perceive their lives to be significantly affected by their acne (8% moderately to severely, 3% severely). It is important to identify and treat such teenagers early to reduce the future socio-economic burden of their acne.     

疥疮患者96例生活质量分析

目的调查疥疮患者的生活质量。方法用10%硫磺乳对96例门诊疥疮患者进行治疗,采用皮肤病生活质量指标,分别对治疗前后的生活质量进行评估。结果疥疮患者的平均生活质量得分为10.09,该表具有较好的内容信度及效度。结论疥疮患者的生活质量较低,10%硫磺乳可以显著提高患者的生活质量。     

甲真菌病患者生活质量调查研究

目的 调查甲真菌病对患者生活质量的影响.方法 采用国际通用的半定势调查问卷,由皮肤科医师对确诊为甲真菌病的患者逐项询问.在全国421家医院进行.结果 共调查55602例甲真菌病患者,其中有效病例47638例,男22616例(47.5%),女25022例(52.5%).指甲真菌病为55.4%,趾甲真菌病为70.6%,指、趾甲共患率26%.甲真菌病对生活质量有显著的负面影响,85.3%的患者主观感到存在健康问题,83.1%的患者具有情感受影响,79.5%出现思维受影响,而社交障碍达到73.3%.甲真菌病对14～30岁年龄组、病程在6个月至1年之间患者的生活质量影响最显著,对女性患者生活质量(主观感受、情感受影响、思维受影响和社交障碍)的影响显著大于男性(P<0.001).感染指/趾甲数目越多,患者生活质量的影响越大.结论 甲真菌病不仅是一个病理和美容问题,还导致患者的生活质量降低,表现为患者对自身健康状况评价降低,影响患者情感、思维并出现社交障碍.     

Impact of Postthyroidectomy Scar on the Quality of Life of Thyroid Cancer Patients

Background

Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy.

Objective

To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL.

Methods

Patients with post-thyroidectomy scars on the neck were recruited. QoL was measured using the Dermatology Life Quality Index (DLQI). Scar characteristics were graded according to Vancouver scar scale (VSS) score.

Results

Ninety-seven patients completed a battery of questions at the time of enrollment. Post-thyroidectomy scars were classified according to morphology as linear flat scars, linear bulging scars, hypertrophic scars or adhesive scars. There were 32 patients (33.0%), 9 patients (9.3%), 41 patients (42.3%) and 15 patients (15.5%), respectively, in each group. The mean total DLQI score was 9.02. Domain 2 (daily activities, 2.87 points), which includes questions about clothing, was the most greatly impacted among patients. The total DLQI scores of patients who have experienced scar-related symptoms were significantly higher than those of patients without symptoms (p<0.05). The VSS scores were 3.09 for linear flat scars, 6.89 for linear bulging scars, 6.29 for hypertrophic scars and 5.60 for adhesive scars. However, the DLQI scores did not significantly differ among scar types or VSS scores.

Conclusion

Post-thyroidectomy scars on the neck affect the QoL of thyroid cancer patients regardless of scar type. Therefore, clinicians should pay attention to the psychological effects of scars on patients and take care to minimize post-thyroidectomy scar.     

瘢痕疙瘩患者128例生活质量评估及影响因素分析

目的 评估瘢痕疙瘩对患者生活质量的影响,并分析其影响因素.方法 应用皮肤病生活质量指数(dermatology life quality index,DLQI)评估瘢痕疙瘩患者的生活质量.结果 共调查了128例瘢痕疙瘩患者,DLQI得分为0～23分,平均为(7.12±4.68)分,患者瘢痕评估量表(patient sc...     

Assessing Quality of Life in Patients with Acne Vulgaris

Diagnosing acne is easy. However, treatment must be adapted to the type and severity of acne, and must also take into account the impact of acne on patients' quality of life. As there is not always a correlation between the severity of acne and its impact on quality of life, it can be helpful for the dermatologist to use a quality of life scale to determine the psychological impact of acne on patients. Either global scales or specific scales for acne can be used. This article reviews the different scales used for evaluation of quality of life in patients with acne.Consideration of specific scales suggests that the Acne Disability Index/Cardiff Acne Disability Index is the easiest scale to use in routine dermatology practice. The Acne Quality of Life scale is particularly useful for evaluating anxiety and depression. The Acne-Specific Quality of Life questionnaire has been mainly validated in adult acne. The Assessment of the Psychological and Social Effects of Acne scale has yet to be validated. Clinical trials indicate that use of global and specific scales together has complementary benefits. In the management of acne, evaluation of quality of life may help to detect depression in teenagers. It may also help to enhance adherence to treatment, which is a crucial factor for success. Finally, there are now validated quality of life scales that are easy to use during patient consultations (taking <2 minutes to complete) by clinicians wishing to evaluate quality of life in patients with acne.