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The response of broiler chickens to a wide range of dietary supplementation of thiamine to broiler breeder diet was studied in order to understand the effects of maternal thiamine nutrition on the status of thiamine indices in the offspring. Thiamine, and thiamine pyrophosphate (TPP) content, and alpha-ketoglutarate dehydrogenase (KGDH) activity were measured in hearts from 20 day old chicken embryos and from chickens at 1, 7, 14, and 21 days of age and in blood at 21 days of age. Total thiamine content in the heart of day old chicks was higher in comparison to 20 day old embryos. Maternal supplementation of thiamine increased heart thiamine in the offspring (p < 0.001), and increased the activity of KGDH in the hearts of day old chicks (p < 0.001), but not in the embryo. The TPP content in the heart increased in response to both maternal and offspring thiamine supplementation (p < 0.001), however the effect of broiler thiamine supplementation was largely independent from the maternal effect. The effect of maternal thiamine nutrition on the offspring's heart KGDH activity was apparent, but the responses to broiler supplementation were dependent largely on the maternal effect. Blood TPP content was not affected by maternal thiamine supplementation (p = 0.39), but thiamine supplementation in the offspring diets increased blood TPP (p < 0.001). Both maternal and offspring thiamine supplementation increased blood free base thiamine content (both p < 0.001). It is concluded from this study that maternal thiamine nutrition affects thiamine status indices and thiamine metabolism of the offspring.  相似文献   

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Cook (2000) advocated parental replacement of thiamine as aroutine accompaniment to in-patient alcohol detoxification.The justification is . . . [Full Text of this Article]REFERENCES  相似文献   

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Both thiamine hydrochloride and thiamine tetrahydrofurfuryl disulfide were added separately to table wines at concentrations equivalent to 0.3 and 1.5 microgram of free thiamine per kJ of caloric energy. The resultant mean increments in thiamine activity, measured by Lactobacillus fermenti microbiological assay after 21 months of storage, were in the range 55 to 103% of the added vitamin, indicative of high bioavailability of thiamine from this source.  相似文献   

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抚触对正常婴儿神经精神及体格发育的影响   总被引:19,自引:1,他引:18  
目的 :探讨抚触对正常婴儿神经精神及体格发育的影响。方法 :采用北京 GESEL L评定量表对 2 8例抚触婴儿及 37例未抚触婴儿进行测评 ,对比两组婴儿适应性、大动作、精细动作、语言、个人—社交 5个能区的差异 ;测量两组婴儿身长、体重 ,进行对比研究。结果 :抚触组婴儿在适应性、语言、个人—社交 3个能区的发育商优于未抚触组 ,两者有显著性差异 (P<0 .0 5 ) ,大动作和精细动作 2个能区的发育商也高于对照组 ,但无显著性差异 ;身长和体重两者无显著性差异。结论 :抚触对婴儿的神经精神发育有明显的促进作用 ,且对婴儿早期神经精神发育的影响比对体格发育的影响更明显  相似文献   

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