视网膜母细胞瘤B超诊断

视网膜母细胞瘤Ｂ超诊断山东省立医院眼科丛培芹临床疑诊为视网膜母细胞瘤９１例，男６４例，女２７例，患者２个半月至１３岁。用美国Ｃｏｏｐｅｒｖｉｓｉｏｎ公司产的ＵｌｔｒａｓｃａｎⅡ超声诊断仪，换能器１０ＭＨｚ，采取直接接触法用Ａ型及Ｂ型超声对双眼扫描探查...     

B型超声在诊断结核性腹水中的应用

Ｂ型超声检查是协助诊断结核性腹水的一种有价值的检查方法。我院自１９９６年３月～１９９７年１０月，应用Ｂ型超声显象诊断结核性腹膜炎并腹水病人２３例，经临床其它辅助检查及抗痨治疗所证实，现总结如下。１　资料和方法２３例病人为我院门诊及住院患者，男性１２例，女性１１例，年龄１７～５７岁。临床表现有消瘦、腹胀、腹痛、发热（１２例为低热或中等发热，２例为高热）、出汗。患者均经血结核抗体及腹水结核抗体检查和胸部摄片检查。仪器为日本产ＥＵＢ—２４０型线阵式实时超声诊断仪，探头频率３－５ＭＨｚ。患者取仰卧位和左…     

惠州中德人造皮肤在烧伤创面的临床应用

随着科学技术的发展，对烧伤病人创面处理的方法越来越多。我院自1992年开始使用惠州中德人造皮肤，对于浅Ⅱ°、深Ⅱ°烧伤创面的愈合取得了满意的效果。本文对此进行探讨，旨在进一步了解人造皮肤的特性、适应证及使用人造皮肤的注意事项，从而提高烧伤病人的治愈率。1临床资料1992－1994年，我院共收治各类烧伤病人417例，选择不同深度的创面6O例（浅Ⅱ°34例，深Ⅱ°20例，Ⅲ°肉芽6例），应用人造皮肤，并进行疗效观察。其中男性38例，女性22例。年龄最高75岁，最低5个月。平均烧伤面积12．5％±10．4％，应用部位主要是面部、躯干及…     

116例盆腔肿块B型超声显像与手术病理符合率分析

１１６例盆腔肿块Ｂ型超声显像与手术病理符合率分析（２７７４００）山东省枣庄市台儿庄人民医院马孝银１资料与方法我院自１９９１～１９９６年间，经妇科和外科诊断为盆腔肿块收入院患者，术前均经Ｂ超检查。采用ＳＡ－１５００型Ｂ超仪，探头频率３．５ＭＨｚ。病人仰...     

286例化学烧伤病人的流行病学调查

目的：为预防化学烧伤提供资料和提出预防对策。回顾性流行病学调查。对象：近１０多年来我科住院的化学烧伤病人。方法：统计分析病人的性别、年龄、职业、烧伤环境、烧伤原因、致伤化学物质、烧伤总面积（ＴＢＳＡ）、烧伤部位、烧伤深度、创面处理、合并症、死亡率。结果：化学烧伤２８６例，占同期烧伤病人的８．５０％，男女之比为３．２７：１，１５～６０岁的病人２２５例（８９．１６％）病人职业以工人最多，共１８８例（６５．７３％），１９４例病人（６７．８３％）是在工作环境受伤。２５３例病人（８８．４６％）是意外受伤，３３例病人（１１．５４％）是人为致伤，最常见的致伤化学物质是酸（６０．８４％），其次为碱（３３．９２％），大多数化学烧伤的面积〈１０％（７２．７３％），面积超过５０％的仅占２．１０％，烧伤部位以四肢多见，占５６．６４％，     

诊断超声对中孕胎儿骨髓细胞形态学的影响

采用临床诊断Ｂ超（常用探头频率３．５ＭＨｚ和最大频率５．０ＭＨｚ）对拟行引产的中孕（孕１６～２６周）妇女（实验组）行腹部超声照射１０ｍｉｎ，２０ｍｉｎ随后行水囊术，抽取引产胎儿骨髓，比较各组骨髓象，观察各组骨髓细胞的超微结构，并与未行Ｂ超照射的引产胎儿（对照组）进行比较，以探讨诊断超声安全性，结果；各实验组与对照组之间，骨髓细胞的超微结构及骨髓象均无差别，提示：目前产产常用诊断剂量超声未引起的孕胎     

毛萝藦中各部位对眼镜蛇毒中毒小鼠的保护作用研究

从毛萝中分离出ＭＨⅠ，ＭＨⅡ，ＭＨⅡ，ＭＨⅡ＿Ｂ等部位和牛奶菜醇（Ｃｏｎｄｕｒｉｔｏｌ），分别观察其对眼镜蛇毒中毒小鼠的保护作用，发现ＭＨⅡ_Ｂ为有效部位，保护率为５０％（Ｐ＜０．０１）。     

诊断超声对中孕胎儿骨髓细胞形态学的影响

采用临床诊断Ｂ超（常用探头频率３．５ＭＨｚ和最大频率５．０ＭＨｚ）对拟行引产的中孕（孕１６～２６周）妇女（实验组）行腹部超声照射１０ｍｉｎ，２０ｍｉｎ，随后行水囊引产术，抽取引产胎儿骨髓，比较各组骨髓象，观察各组骨髓细胞的超微结构，并与未行Ｂ超照射的引产胎儿（对照组）进行比较，以探讨诊断超声的安全性。结果：各实验组与对照组之间，骨髓细胞的超微结构及骨髓象均无差别。提示：目前产科常用诊断剂量超声未引起中孕胎儿骨髓细胞形态学的改变     

34例膀胱肿瘤的超声诊断

３４例膀胱肿瘤的超声诊断高邮市城北医院陈大梅我院自１９８９年以来应用超声检查３４例膀胱肿瘤病人，并经手术及膀胱镜病理证实，报告如下。１资料与方法男性３０例，女性４例，年龄５１～７６岁，男女之比７∶１。采用ＥＵＢ－３１５型超声诊断仪，频率３．５ＭＨｚ。...     

应用B型超声对胆结石定性分类诊断符合率的探讨

本文１００例胆结石病人，术前经Ｂ型超声（Ｂ超）分类诊断。手术取石后用偏光显微镜及吸收光谱作结石定性分析，确定胆结石的性质，以此探讨术前Ｂ超对胆结石定性诊断的符合率。结果表明术前Ｂ超对胆固醇结石诊断符合率为７３％；对胆色素结石诊断符合率为６２％；而对混合结石的诊断符合率仅为１．６％。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.