共查询到20条相似文献,搜索用时 15 毫秒
1.
Chorionic gonadotropin is shown to alter lactate dehydrogenase and alcohol dehydrogenase activity in the pathologically altered
liver and to exert a regulatory effect on the catalytic properties of these enzymes.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N
o
6, pp. 590–591, June, 1994
Presented by Yu. A. Romanov, Member of the Russian Academy of Medical Sciences 相似文献
2.
I. M. Nosova T. L. Zaets T. I. Kotkina 《Bulletin of experimental biology and medicine》1977,84(3):1265-1268
Activity of lactate dehydrogenase (LD) and its isozymes in the injured zone and in adjacent areas of the skin was investigated at various times after infliction of burns in rats. On the 1st–8th day after burning total LD activity was reduced in the zone of the scab and in the underlying tissues by 70–80% and in the border and intact skin by 50%. These changes were accompanied by changes in the LD isozyme spectrum in the injured tissue: On the 1st day the activity of fraction 5 was sharply increased and activity of fractions 2 and 3 reduced; by the 8th day, on the other hand, some decrease in activity of fraction 5 and an increase in activity of fractions 2 and 3 were observed. By the 14th–22nd day after burning total LD activity remained low, the LD isozyme spectrum in the border and scab was largely restored to normal, whereas in the underlying tissue changes in the relative proportions of LD isozymes were still present (a decrease in activity of fractions 1–3 and an increase in activity of fraction 5).Laboratory of Biochemistry, A. V. Vishnevskii Institute of Surgery, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR M. I. Kuzin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 9, pp. 294–297, September, 1977. 相似文献
3.
F. N. Gil'miyarova V. M. Radomskaya B. S. Mirzaev V. Yu. Golenishchev O. B. Anikeeva T. I. Stukolova N. V. Shamina 《Bulletin of experimental biology and medicine》1994,117(5):476-477
Active realization of 2-oxoglutarate, malate, and oxaloacetate is observed after administration of lactate dehydrogenase.
The levels of transamination and urea formation are within the normal range. By its targeting of oxidative metabolism, lactate
dehydrogenase may be regarded as a biogenic factor correcting the glycolytic processes.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N
o
5, pp. 480–481, May, 1994
Presented by T. T. Berezov, Member of the Russian Academy of Medical Sciences 相似文献
4.
N. I. Gryazeva A. V. Shurlygina L. V. Verbitskaya E. V. Mel'nikova N. N. Kudryavtseva V. A. Trufakin 《Bulletin of experimental biology and medicine》2000,129(1):44-46
The influence of social status on some immunological characteristics in experimental animals was studied (sensory contact
model). Lactate dehydrogenase activity in blood lymphocytes changed similarly in aggressive and submissive mice probably due
to social stress. The activity of succinate dehydrogenase changed differently and correlated with the type of social behavior.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 1, pp. 53–55, January 2000 相似文献
5.
I. M. Fedorova R. A. Danilova I. P. Ashmarin 《Bulletin of experimental biology and medicine》1994,118(4):1050-1052
Active immunization of white rats with alcohol dehydrogenase (horse ADH-1), a major ethanol-metabolizing enzyme shown to cause
considerable and long-term inhibition of alcohol consumption, did not have adverse effects on their behavior. Rather, the
rats showed enhanced motor and orienting-exploratory activities, developed conditioned responses (with both positive and negative
reinforcements) more readily, and spent less time in a state of immobilization in the forced swimming test as compared with
nonimmunized controls.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
o
10, pp. 349–351, October, 1994 相似文献
6.
N. G. Khrushchov V. M. Faktor I. V. Uryvaeva É. V. Chernyshova 《Bulletin of experimental biology and medicine》1977,83(2):222-224
It was shown by the splenic colonies method that hematopoietic stem cells are present in the intact liver of adult CBA mice. Their number increases during regeneration of the liver after partial hepatectomy.N. K. Kol'tsov Institute of Developmental Biology, Academy of Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 2, pp. 209–210, February, 1977. 相似文献
7.
O. D. Mishnev A. P. Ettinger A. I. Shchegolev M. V. Anurov S. P. Yavolov 《Bulletin of experimental biology and medicine》1995,119(1):101-104
A histophotometric study of the liver dehydrogenase activity reveals the nature of changes of enzymatic homeostasis and its
periodicity in the dynamics of endotoxinemia in dogs. A compensatory reaction to lipopolysaccharide administration develops
during the first two hours. A decrease of dehydrogenase and diaphorase activity and the development of structural damage to
hepatocytes appear later. It is shown that the activation of free-radical oxidation as well as an increase of the level of
medium-sized molecules in the blood plasma play a key role in the pathogenesis of liver damage.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No. 1, pp. 105–108, January, 1995
Presented by V. V. Kupriyanov, Member of the Russian Academy of Medical Sciences 相似文献
8.
Z. A. Ryabinina 《Bulletin of experimental biology and medicine》1976,82(2):1236-1239
A comparative cytological study was made of the control and regenerating liver in two strains of rats: August and cotton-tail. Two-thirds of the liver was removed from both groups of experimental animals and the intact organ served as the control. The animals were killed five or six at a time 30 h and 3, 8, 42, and 120 days after partial hepatectomy. The number of binuclear cells, the dimensions of the mononuclear hepatocytes and of their nuclei, and the mitotic activity and ploidy of the cells were studied. With the exception of mitotic activity, the regenerating and intact liver of the August rats differed from the regenerating and intact liver of the cotton-tail rats in all the above-mentioned cytological parameters. It is concluded that differences in the cytological parameters between the two different strains are due to the genotype of the particular strain.Laboratory of Growth and Development, Institute of Human Morphology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 987–989, August, 1976. 相似文献
9.
L. M. Strigun E. N. Chirkova G. G. Grigor'eva L. Yu. Bazhenova 《Bulletin of experimental biology and medicine》1995,120(3):933-937
The common variation pattern and the synchronous increases of enzymatic and solar activity are explained by the identical
frequencies of the bio- and heliorhythms and by the strict phase coordination of the latter. It is shown to be possible to
predict enzymatic activity according to the sum of the resonance heliorhythms. The wave genesis of the resonance between enzymatic
and solar fluctuations is confirmed by the fact that the periods of the bio- and heliorhythms are the same as the wave periods
of planets.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N
o
9, pp. 294–298, September, 1995
Presented by F. I. Komarov, Member of the Russian Academy of Medical Sciences 相似文献
10.
The intensity of cortisol metabolism was studied during perfusion of the liver in situ with solutions containing different concentrations of cortisol. Under these circumstances metabolism was shown to take place chiefly in the direction of cortisone formation. With an increase in the cortisol concentration in the perfusion fluid the intensity of its metabolism in the liver tissue also increased. During anaphylactic changes in the liver tissue the intensity of conversion of cortisol into cortisone was reduced, indicating a disturbance of the oxidation of cortisol. In experimental allergic encephalomyelitis the intensity of cortisol metabolism also was reduced.Department of General Pathology, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. M. Chernukh.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 981–984, August, 1976. 相似文献
11.
12.
O. M. Petrashchuk O. V. Smirnova A. N. Smirnov 《Bulletin of experimental biology and medicine》1994,118(3):962-965
Strong expression of prolactin receptors in sinusoidal domains and cytoplasmic granules of hepatocytes, which is independent
of cell location in the hepatic lobule and is positively regulated by estrogens, is revealed in pubertal female rats. In estrogen-treated
animals, Prolactin receptors are also exposed in the perinuclear space of some hepatocytes surrounding the central veins.
Estrogens regulate the intensity of prolactin receptors expression in hepatocytes, but not the number of cells containing
these receptors.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
o
9, pp. 264–267, September, 1994
Presented by I. P. Ashmarin, Member of the Russian Academy of Medical Sciences 相似文献
13.
I. M. Nosova 《Bulletin of experimental biology and medicine》1975,80(2):907-909
Changes in the activity of malate dehydrogenase (MD) and its isozymes in the blood serum and heart muscle of rats were investigated during hypoxia and under the influence of ATP and cocarboxylase. An additional cathodic isozyme (MD4) appeared in the blood serum during hypoxia. Under the influence of ATP and cocarboxylase the metabolic changes in the blood and myocardium induced by hypoxia did not correlate fully.Presented by Academician of the Academy of Medical Sciences of the USSR A. A. Vishnevskii.Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 8, pp. 48–50, August, 1975. 相似文献
14.
P. A. Vunder V. P. Vunder T. A. Andronova 《Bulletin of experimental biology and medicine》1976,82(5):1718-1720
The -adrenergic blocking drug phentolamine was injected into male rats 1 h before resection of 70% of the liver and again 24 h after the operation. Phentolamine inhibited mitotic activity of the regenerating liver. Two injections of propranolol, a -adrenergic blocking drug, at the same times caused an increase in mitotic activity. It was concluded that adrenalin, which excites -adrenergic receptors, may inhibit regeneration. By its action through -adrenergic receptors, however, adrenalin stimulates this process.Department of Physiology of Animals, N. G. Chernyshevskii Saratov University. Central Scientific-Research Laboratory, Saratov Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 11, pp. 1373–1374, November, 1976. 相似文献
15.
V. I. Urbanovich T. A. Vylegzhanina O. A. Maneeva T. E. Kuznetsova E. L. Ryzhkovskaya 《Bulletin of experimental biology and medicine》1999,127(5):511-514
In experiments on guinea pigs, the nerve-tissue relationships in gingival papillae were studied under conditions of experimental
inflammation induced by local (turpentine injection) and general (whole-body γ-irradiation). It is found that structural and
metabolic changes in the lamina propria and epithelium of the gingival mucosa correlate with disturbances in trophic influences
from the sympathetic nervous system.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 5, pp. 564–568, May, 1999 相似文献
16.
17.
18.
S. I. Kolesnikov Yu. V. Gladyshev L. N. Demidova N. G. Gladysheva S. V. Alisievich 《Bulletin of experimental biology and medicine》1997,123(5):509-512
After 2 days of aseptic inflammation in pregnant rats the number of hematopoietic lineage cells in the embryonic liver decreased,
while proliferative activity of cells in the embryonic lung increased. Degenerative changes were noted in the placenta.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 5, pp. 584–587, May, 1997 相似文献
19.
V. V. Ryvnyak V. S. Gudumak E. S. Onya 《Bulletin of experimental biology and medicine》1995,120(3):952-953
The activity of aminopeptidase M in rat liver is studied electron histochemically. The enzyme is shown to be localized in
the lysosomes of Kupffer's cells and endotheliocytes, and extracellularly on hepatocyte microvilli.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N
o
9, pp. 312–314, September, 1995
Presented by D. S. Sarkisov, Member of the Russian Academy of Medical Sciences 相似文献
20.
Comparison of the effects of stimulation of vagus nerves in intact and desympathized rats showed differences in the variation
pulsogram parameters in different age groups. A similar time course of variation pulsogram parameters in response to vagus
nerve stimulation was observed in normal and experimental rats.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 6, pp. 703–706, June, 1997 相似文献