皮肤血管肉瘤一例并文献复习

报道1例皮肤血管肉瘤并对相关文献进行复习。患者，女，66岁。因头皮结节1年，额部瘀斑8个月就诊。皮肤科查体：头皮散在肤色至淡红色结节，表面可见少量鳞屑及毛细血管扩张，伴脱发。右侧额颞部可见水肿性紫红色斑片，压之不褪色。皮肤组织病理及免疫组织化学染色符合皮肤血管肉瘤的诊断。局部行放射治疗，目前仍在随访中。     

皮肤窦性组织细胞增生症一例并文献复习

报道1例皮肤窦性组织细胞增生症并对文献进行复习。患者,女,56岁,右上肢暗红色结节、斑块2年余,无系统受累。组织病理：真皮内大量组织细胞、淋巴细胞,可见组织细胞伸入现象。免疫组化：S-100（+）、CD68（+）、CD1a（-）。外用卤米松等治疗后皮损范围已明显缩小。     

Cutaneous protothecosis: a case report and review of the literature

Protothecosis is a rare cause of systemic and/or cutaneous infection. Because approximately 100 cases of human infection with Prototheca wickerhamii have been reported, little is known about the pathogenesis of this infection. Cases include both immunocompetent and immunocompromised patients. However, most cases contain an element of immune compromise, either local or systemic. We present a case of an 81-year-old white woman with a history of multiple nonmelanoma skin cancers, including squamous and basal cell carcinomas and actinic keratoses, throughout her legs and thighs bilaterally. She presented to a central Florida dermatology clinic with complaints of persistent bumps on her right lower leg despite therapy with diclofenac sodium gel 3% and 5-fluorouracil cream 5%. Biopsies of skin specimens from the right lower leg revealed a dermal abscess that contained spherical funguslike organisms, with periodic acid-Schiff staining revealing 6- to 10-microm organisms with internal septations, which are characteristic of P wickerhamii.     

Cutaneous granuloma with ataxia telangiectasia—a case report and review of literature

A patient is reported who had ataxia telangiectasia with multiple cutaneous lesions mainly on the limbs, which showed atrophy and scarring. Histopathology of these skin lesions showed tuberculoid granulomas without frank collagen necrobiosis in the dermis. Chromosomal analysis revealed a translocation between 7 and 14 as well as deletion of chromosomes 4 and 6.     

Cutaneous lymphadenoma: a case report and review of the literature

We report a case of cutaneous lymphadenoma, a tumour first described by Santa Cruz and Barr under the name of‘lymphoepithelial tumour1. Twenty-three cases have been reported to date. The commonest site is the head and neck, and it is most commonly diagnosed in the fourth and fifth decades. The usual clinical diagnosis is basal ceil carcinoma. To date, no recurrences have been observed after iocai excision. The tumour is C(miposed of dermal lobules with a biphasic pattern of epithelial and lymphoid cells. It has been suggested that it arises as a result of faulty interaction between lymphocytes and epithelial cells.     

Cutaneous granulomatous vasculitis associated with chronic lymphocytic leukemia: case report and review of literature of a rare entity

Cutaneous granulomatous vasculitis associated with lymphoproliferative disorders is a rare entity, with only 14 cases previously reported in the English literature. Patients generally present with nodules or ulcers involving the extremities, which can appear months or years before or after onset of systemic disease. Granulomatous vasculitis has a poor prognosis when associated with underlying lymphoproliferative disorders, with the majority of reported cases fatal. Knowledge of this unusual entity is important to allow for proper clinical evaluation, follow-up, and therapy. We report a 77-year-old female with chronic lymphocytic leukemia and granulomatous vasculitis, which highlights the features of this association, and expands the clinical data.     

皮肤母细胞性NK细胞淋巴瘤一例

患者男,20岁,因右大腿起皮疹5个月,泛发全身2个月余就诊.体检:躯干、四肢散在分布的蚕豆至鸽蛋大小的暗红色结节,表面无破溃,质韧,无压痛.全身浅表淋巴结未扪及.背部皮损组织病理及免疫组化染色证实为母细胞性NK细胞淋巴瘤.经依托泊苷+环磷酰胺+长春新碱+地塞米松+甲氨蝶呤方案化疗后缓解.     

Cutaneous schistosomiasis: report of a case and review of the literature

Cutaneous disease is a previously reported but unusual presentation for schistosomiasis. We report a case of Schistosoma haematobium infection that appeared 3 years after exposure, with skin lesions as the sole manifestation. The diagnosis was made on the basis of a routine skin biopsy and the patient did well after therapy with praziquantel. Dermatologists should be aware of this presentation of schistosomiasis when evaluating patients with unusual skin lesions who have traveled in areas where schistosomiasis is endemic.     

Cutaneous Hodgkin's lymphoma: a case report and review of the literature

报告1例皮肤霍奇金淋巴瘤.患者男,28岁.因右侧锁骨上不规则鲜红色斑块1年就诊,全身系统检查未见肿大淋巴结和内脏肿瘤,经皮损组织病理和免疫组化检查诊断为皮肤霍奇金淋巴瘤.     

Cutaneous pili migrans: a case report and review of the literature

Background  Cutaneous pili migrans is a rare condition in which the hair shaft penetrates the superficial layer of the skin and produces a creeping eruption mimicking the lesion of cutaneous larva migrans.
Methods  We report a 28-year-old Chinese man who presented with a painful and slow-moving black, linear eruption on the left sole after walking on a waterlogged street wearing slippers without socks.
Results  The lesion started at the anterior part of the foot near the external border, extending linearly along Langer's line towards the lateral side. It then turned in a U-shaped direction and moved across the foot to the other side, where it made a right angle and moved along the internal side of the foot. The lesion was reminiscent of cutaneous larva migrans. Walking made the line move more quickly. Physical examination showed that there was a broken epidermis at the probable entrance and a black thin line at the advancing end of the lesion. The black line was demonstrated to be a hair shaft with a sharp head by a shallow incision of the skin and examination under a microscope. After removal of the hair, the pain disappeared and the lesion diminished immediately, leaving slight pigmentation.
Conclusion  The broken epidermis may be one of the main reasons for the hair shaft entering the skin. The force of body motion caused movement, which was made easier by the sharp head of the hair shaft. Hair can produce an eruption reminiscent of cutaneous larva migrans.     

Aplasia cutis congenita type V: a case report and review of the literature

Aplasia cutis congenita (ACC) is a relatively rare congenital anomaly that most commonly occurs as a solitary cutaneous defect on the scalp. Depth of involvement varies, and involvement of deeper calvarium and dural structures can be seen in more severe cases. Multiple classification systems have been devised with the Frieden Classification System being the most widely adopted. Using this system, we describe a patient that developed Type V ACC with associated fetal papyraceous. The child healed remarkably well with the application of petrolatum impregnated gauze and topical silver sulfadiazine twice daily for approximately 4 weeks. The child was noted to have no significant contractures or complications at 6‐months and 1‐year follow‐up exams. Herein, we review the current literature on type V ACC including a discussion of treatment options.     

Bullous aplasia cutis congenita: case report and review of the literature

Aplasia cutis congenita is a rare condition characterized by the absence of skin and sometimes other underlying structures such as bone or dura. It can be a part of various syndromes and can be associated with multiple genetic diseases, malformation patterns, or a combination of all. It is even considered as a form frustre of a neural tube defect in several literatures. Bullous aplasia cutis congenita is a clinical subtype of the condition, with extremely few cases reported in the literature. It presents as a cystic or bullous lesion at birth, which eventually transforms into an atrophic, flat scar covered by a thin epithelium. Some cases present with a dark collar hair sign around the lesion, which can be even more indicative of an underlying neural tube defect. Management remains controversial and depends on the characteristics of the lesion, but conservative treatment is usually chosen.     

Cutaneous and lymphadenopathic Kaposi's sarcoma: a case report and review of literature

Kaposi's sarcoma (KS) of childhood is an extremely rare and unexplained disease. It is usually associated with immunosuppression and human herpes virus 8 (HHV-8) infection. It can involve skin, mucous membranes, lymph nodes and viscera. This investigation describes a case of a 3-year-old boy with cutaneous and lymphangiopathic KS. Initially, the patient presented with cutaneous lesions of KS behind the right ear. Two months later, the disease disseminated not only cutaneously but also to the cervical, axillary and inguinal lymph nodes. Immunological evaluation showed severe lymphocytopenia but without evidence of human immunodeficiency virus infection. The vascular nature of the lesion was supported by positive staining for CD31 and CD34. This study examines the clinicopathologic features of KS in children and summarizes the relevant literature.     

Cutaneous basal cell carcinosarcoma: case report and literature review

Carcinosarcomas are malignant neoplasms with biphasic carcinomatous and sarcomatous or sarcoma‐like components. In general, the sarcomatous component is accepted to be the result of divergent mesenchymal differentiation of the epithelial component. Although well characterized in some anatomic locations (e.g. uterus, upper aerodigestive tract and lung), carcinosarcomas of the skin are rare. Reported epithelial components include squamous, adnexal, neuroendocrine and basaloid. Including this case, only 47 cases of primary cutaneous basal cell carcinosarcoma have been reported in the literature to date. We performed an extensive immunophenotypic evaluation in our case, which confirmed the previously reported coexpression of p53 in both components, and revealed a hitherto unreported coexpression of p16 and p63. Additionally, this report reviews the clinical, pathologic, immunophenotypic characteristics and outcomes of the basal cell carcinosarcomas reported in the literature, in order to emphasize the overall uniform characteristics and clinical behavior of this neoplasm.     

Cutaneous melanoma in a patient with neurofibromatosis: a case report and review of the literature

We report the occurrence of a malignant melanoma in a patient with neurofibromatosis (von Recklinghausen's disease; NF 1). Neurofibromatosis, like malignant melanoma, is believed to be a disorder of neural crest origin, and is associated with a number of different malignancies, but a definite association between cutaneous malignant melanoma and neurofibromatosis has not been established. We describe a patient with a malignant melanoma and with neurofibromatosis, and review the literature pertinent to this topic. The malignant melanoma was not related to a café-aulait patch or congenital naevus. The paucity of reports of patients with neurofibromatosis associated with cutaneous malignant melanoma suggests that these diseases probably do not occur together with any greater frequency than that determined by chance alone.     

Cutaneous lymphoid hyperplasia: a case report and brief review of the literature

Cutaneous lymphoid hyperplasia (CLH) is considered a benign lymphoid reactive process that results from various antigenic stimuli and may have potential for progression to overt lymphoma. CLH lesions may closely resemble lymphoma both clinically and histologically. We present a case of a 54-year-old woman who spontaneously developed lesions of unknown cause consistent with CLH. We also review the literature and discuss the etiology, clinical features, diagnosis, and management of CLH.     

以皮肤结节为显著表现的先天性白血病一例并文献复习

报道1例出生时以皮肤结节为显著表现的先天性白血病并文献复习.患儿,女,出生时即全身弥漫性多发大小不等紫红色结节;外周血示白细胞284.24×109/L,原始细胞90％;皮肤病理示真皮及脂肪层弥漫性密集分布大量非典型细胞,表皮未受累,免疫组化染色CD68、CD43阳性;骨髓穿刺示白细胞数明显增高,以原始和幼稚单核细胞为主...