单髁膝置换术与全膝关节置换术治疗膝关节内侧间室骨关节炎的近期疗效比较

目的探讨单髁膝置换术(UKA)与全膝关节置换术(TKA)治疗膝关节内侧间室骨关节炎的近期疗效。方法回顾性分析2017-01～2017-10对因膝关节内侧间室骨关节炎行UKA治疗患者15例(15膝),选取同期行TKA治疗患者30例(34膝)作为对照组。术前评估并记录两组患者的疼痛视觉模拟评分(VAS)、美国特种外科医院(HSS)评分、膝关节活动度(ROM),记录手术时间、术中出血量、术后3 d血红蛋白(Hb)下降量、术后3个月及1年VAS评分、HSS评分、ROM。结果所有患者手术顺利完成。两组患者年龄、体重指数(BMI)比较差异无统计学意义(P0.05)。UKA组手术时间、术中出血量、术后3 d Hb下降量、VAS评分均低于TKA组,而HSS评分、ROM高于TKA组,差异均有统计学意义(P0.05)。结论膝关节内侧间室骨关节炎的手术治疗选择UKA更优于TKA,UKA具有手术时间短、术中出血量少、术后恢复快、功能恢复良好等优点,能够取得良好的近期疗效。     

两种手术方式治疗膝关节内侧单间室骨性关节炎疗效对比分析

目的探讨膝关节单髁置换术(UKA)和全膝关节置换术(TKA)两种手术方式治疗膝关节内侧单间室骨性关节炎的应用效果。方法根据手术方式不同,将研究对象分为两组:UKA组53例和TKA组61例,收集两组病例相关资料,对手术应用效果进行对比分析和评价。结果经SAS9.1统计分析,两组病例切口长度、手术用时、术中出血量、术后VAS疼痛评分、首次直腿抬高时间、住院时间以及术后感染发生率差异均有统计学意义(均P0.05);术后1d关节活动度ROM和功能HSS评分差异无统计学意义(均P0.05)。结论两种手术方式均取得满意效果,但各有特点。UKA术前须严格病例筛选,应引起重视。     

微创全膝关节置换术的早期疗效观察

目的探讨微创全膝关节置换术的早期疗效。方法对60例(70膝)入组患者随机分成2组进行前瞻性对照研究。微创组取股内侧肌下切口入路,采用美国捷迈公司特殊的微创器械,利用膝关节屈伸位置的不断变化和"移动窗口"技术行微创全膝关节置换术。对照组采用标准全膝关节置换手术。比较2组病例的膝关节评分(knee society score,KSS)、关节活动度(ROM)增加度数、视觉模拟评分法(VAS)、引流管出血量、切口长度和术后无协助负重行走时间(下地时间)等指标。结果术后1周KSS评分、引流管出血量、切口长度和术后无协助负重行走时间(下地时间)方面,微创组手术效果优于传统对照组,2组差异有统计学意义(P<0.05)。术后12月2组KSS评分、ROM增加度数、VAS比较,差异无统计学意义(P>0.05)。结论微创全膝关节置换术具有手术切口小、出血少、股四头肌功能干扰少等优点,可以减轻术后疼痛,尽早恢复下肢活动,短期随访手术效果优良。     

超声引导下腰方肌阻滞对全髋关节置换患者术后疼痛和恢复质量的影响

目的 探讨超声引导下腰方肌阻滞(QLB)对行全髋关节置换术(THA)患者术后疼痛和恢复质量的影响。方法 选择2018年12月至2019年9月徐州医科大学附属医院择期全身麻醉下行THA患者60例,采用随机数表法随机将患者分为对照组(C组)和阻滞组(Q组),每组30例。Q组患者在全身麻醉诱导前行腰方肌阻滞,C组不进行阻滞。患者术后均使用自控静脉镇痛泵。评估患者术后4、8、24、48h静息时和运动时视觉模拟疼痛评分(VAS)。采用15项恢复质量评分量表(QoR-15)评估患者术后24h恢复质量;采用阿森斯失眠量表(AIS)评估患者术后第1晚睡眠质量;采用躁动评分评估患者苏醒期躁动状态;采用Ramsay镇静评分评估患者拔管后10min镇静状态。记录患者术中全麻药的用量、术后补救镇痛例数、不良反应和住院时间。采用SPSS19.0 统计软件进行数据分析。结果 Q组患者术后4、8、24h静息时VAS评分分别为1(1,2)、2(1,2)、2(1,3);C组患者分别为3(2,3)、3(2,4)、3(2,5),差异均有统计学意义(均P＜0.05)。Q组患者术后4、8、24h运动时VAS评分分别为3(2,4)、3(2,4)、5(4,6);C组患者分别为6(5,7)、6(5,8)、7(6,8),差异有统计学意义(均P＜0.05)。2组患者术后48h VAS评分比较,差异无统计学意义(P＞0.05)。Q组患者术后24h QoR-15评分显著高于C组[(99.2±9.7)和(74.4±9.1);P＜0.05],术后第1晚阿森斯失眠量表评分显著低于C组[(9.8±2.4)和(16.0±3.6);P＜0.05]。Q组患者苏醒期躁动评分显著低于C组[0(0,1)和2(1,2);P＜0.05],拔管后10min Ramsay镇静评分显著高于C组[3(2,3)和1(1,1);P＜0.05]。Q组患者术中瑞芬太尼用量和术后补救镇痛率显著低于C组[(1.15±0.23)和(1.73±0.26)mg, 23.3%和53.3%;均P＜0.05]。2组患者住院时间和恶心呕吐发生率比较,差异无统计学意义(P＞0.05)。结论 QLB为THA患者提供良好的术后镇痛,并提高术后早期恢复质量。     

自拟四肢洗方对全膝关节置换术后患者疼痛及膝功能康复影响的研究

目的评估自拟四肢洗方对全膝关节置换术后患者膝关节疼痛及功能康复的影响。方法回顾性分析自2018年1月至2019年6月在复旦大学附属中山医院骨科行全膝关节置换术的患者,根据是否进行了2个疗程自拟四肢洗方的治疗,分为四肢洗方组和对照组;分析2组患者术后1、3、6月随访时的疼痛评分(VAS),膝关节功能评分(KSS)。结果四肢洗方组共纳入122例患者,对照组纳入109例,2组患者在年龄、性别、BMI、手术侧和内/外翻膝比例差异无统计学意义;四肢洗方组患者在1月和3月随访时VAS评分和KSS评分优于对照组,6月时2组差异无统计学意义。结论使用自拟四肢洗方可对全膝关节置换术后患者膝关节疼痛及功能康复有积极的意义。     

膝关节镜联合腓骨近端截骨术治疗老年膝关节骨性关节炎的疗效及对血清炎症因子的影响

目的探讨膝关节镜联合腓骨近端截骨术治疗老年膝关节骨性关节炎(KOA)的疗效及对血清炎症因子的影响。方法老年KOA患者68例。根据随机数表法分为对照组(n=34)与研究组(n=34),对照组行膝关节镜清理治疗,研究组在对照组基础上联合腓骨近端截骨术治疗,比较两组手术时间、住院时间,术前与术后6个月美国特种外科医院(HSS)、美国膝关节协会评分(KSS)评分、视觉模拟疼痛评分(VAS)及炎症因子水平,同时观察并发症发生情况。结果研究组手术时间显著高于对照组(P0.05);两组住院时间比较无统计学差异(P0.05)。两组术后6个月KSS、KSS评分较术前升高,且研究组高于对照组(P0.05);VAS评分较术前降低,且研究组低于对照组(P0.05)。两组患者术后6个月白介素(IL)-6、肿瘤坏死因子(TNF)-α水平均较术前明显降低,且研究组明显低于对照组(P0.05)。两组并发症发生率对比无统计学差异(P0.05)。结论膝关节镜联合腓骨近端截骨术治疗老年KOA患者疗效确切,可改善患者的膝关节功能,同时降低炎症因子水平,并发症发生率较低。     

人工全膝关节置换联合螺钉治疗重度膝内翻畸形合并胫骨平台沉降的临床疗效探讨

［摘要］　目的　探讨人工全膝关节置换联合螺钉治疗重度膝内翻畸形合并胫骨平台沉降的临床疗效。方法　2016-08～2019-01收治11例（16膝）内翻畸形合并胫骨平台沉降患者,均为女性,采用人工全膝关节置换手术治疗。根据X线片比较术前和术后膝内翻角度,应用术前膝关节学会评分系统（KSS）临床评分为（40.28±11.34）分、功能评分为（48.32±15.54）分,膝关节活动度(range of motion,ROM)为（89.76±14.13）°,胫股角（femoral tibia angle,FTA）为（15.04±3.38）°。结果　手术时间为75～90 min,平均80 min;显性失血量为200～700 ml,平均430 ml;住院时间为10～15 d,平均12.5 d。随访时间为6～21个月,平均15个月。复查X线片测量膝关节FTA为（5.87±1.10）°,下肢力线均恢复正常。随访期间无假体松动、下沉。末次随访时,膝关节KSS临床评分为（87.33±5.42）分,功能评分为（89.45±5.94）分,膝关节ROM为（107.54±10.68）°,与术前比较差异有统计学意义(P<0.05)。结论　对于膝内翻畸形合并胫骨平台沉降患者,人工全膝关节置换术后下肢力线恢复良好,螺钉联合骨水泥支撑小面积胫骨平台沉降,膝关节活动度、稳定性及功能恢复满意。     

针刺四关联合塞来昔布对全膝关节置换患者围术期超前镇痛的疗效

目的探讨针刺四关联合塞来昔布在全膝关节置换(TKA)患者围术期中超前镇痛的临床疗效。方法行人工TKA患者60例,随机分为针药组及对照组各30例,分别在手术前2 d及术后2 w对患者进行镇痛治疗,并用疼痛视觉模拟评分(VAS)及膝关节协会评分(KSS)评定,观察治疗后的近远疗效。结果治疗后,手术前1 d、术后1、2 d及术后7 d的静息/活动VAS评分,两组差异有统计学意义(P0.05);术后7 d及术后14 d两组KSS评分差异有统计学意义(P0.05);针药组总体镇痛满意度明显高于对照组(P0.05)。结论针刺四关联合塞来昔布用于全膝关节置换术患者,可以获得比单用塞来昔布更好的镇痛效果。     

单髁置换术治疗老年单间室膝关节骨关节炎的中期疗效

目的评价单髁置换(UKA)术治疗老年单间室膝关节骨关节炎(OA)的中期临床疗效。方法回顾性分析2007年1月至2009年1月空军总医院骨科收治的单间室膝关节OA患者23例(24膝),其中男性4例,女性19例,年龄52~71岁,平均年龄61.3岁,体质量55~69 kg,平均62.4 kg。由同一医师行UKA术,通过比较患者术前和术后末次随访时膝关节屈曲活动度(ROM)、膝关节学会评分(KSS)及西大略和麦克马斯特大学骨关节指数(WOMAC)进行中期临床疗效评估。采用SPSS 17.0软件对数据进行统计学分析,计量资料用均数±标准差(x±s)表示,术前、术后膝关节ROM、KSS、WOMAC比较采用配对t检验,以P0.05为差异有统计学意义。结果所有患者经关节镜探查无UKA术禁忌证,未转行全膝置换(TKA)术,均顺利完成手术。手术时间为(93.8±11.6)min,术中出血量为(196.7±40.1)ml。患者术后无感染、无深静脉血栓发生,手术切口为I/甲愈合。患者随访5~7年,平均6.3年,相比手术前,随访末次时的ROM、KSS、WOMAC提高,差异有统计学意义(P0.001)。患者随访期间无假体松动、移位及关节翻修等严重并发症。结论在严格掌握手术适应证的前提下,UKA治疗单间室膝关节OA可获得良好的中期疗效,具有创伤小,恢复快等优点,但长期疗效还有待研究。     

加速康复外科管理对膝关节置换老年患者手术效果的影响

目的探究加速康复外科管理对膝关节置换老年患者手术效果影响。方法选取168例膝关节置换老年患者为研究对象,将其依据随机数字表法分为对照组和观察组,各84例。两组均行全膝关节置换手术治疗,对照组围术期管理采用常规方式,观察组给予加速康复外科模式围术期管理。比较两组围术期情况、视觉模拟量表(VAS)评分、美国特种外科医院(HSS)评分、关节活动度(ROM)和并发症情况。结果观察组手术时间、术后引流量、肛门排气时间和住院天数均明显低于对照组,24 h血红蛋白水平明显高于对照组(均P<0.05)。术前观察组与对照组VAS评分、HSS评分和ROM比较差异无统计学意义(P>0.05);术后两组VAS评分均明显降低,HSS评分均明显升高,且观察组VAS评分和ROM明显低于对照组,HSS评分明显高于对照组(P<0.05)。观察组与对照组并发症总发生率差异无统计学意义(P>0.05)。结论膝关节置换老年患者经加速康复外科模式治疗能够有效改善围术期情况,缓解疼痛,改善膝关节功能,且无严重并发症。     

悬吊技术联合Mulligan手法对膝骨关节炎老年人群运动后疼痛的康复效果

目的 探究悬吊技术联合Mulligan手法用于膝骨关节炎老年人运动后膝关节疼痛康复的效果.方法 选取84例单侧膝关节运动后疼痛的膝骨关节炎老年患者,依据随机数字表法分为观察组和对照组,各42例.对照组给予常规物理治疗与悬吊训练治疗,观察组在对照组基础上给予Mulligan技术治疗.比较两组治疗开始前与治疗后视觉模拟评分(VAS)疼痛评分、QOL-BREF评分、LEFS下肢功能评分、膝关节功能评分、关节活动度、四头肌与腘绳肌肌力.结果 两组治疗后VAS评分明显降低(P<0.05),且观察组VAS评分明显低于对照组(P<0.05).两组治疗后QOL-BREF评分/LEFS评分、膝关节功能评分、关节活动度、四头肌与腘绳肌肌力较治疗前明显提高(P<0.05),且治疗后观察组QOL-BREF评分/LEFS评分、膝关节功能评分、关节活动度、四头肌与腘绳肌肌力明显高于对照组(P<0.05).结论 对于膝关节运动后疼痛的膝骨关节炎老年患者,悬吊技术联合Mulligan手法,能有效缓解膝关节疼痛、促进膝关节功能恢复,提高患者生活质量.     

Patellofemoral osteoarthritis does not influence clinical outcomes of fixed-bearing unicompartmental knee arthroplasty

Unicompartmental knee arthroplasty (UKA) is an ideal surgical approach in treatment of end-stage knee osteoarthritis (KOA), however, indications of UKA have been controversial, and the radiographic and symptomatic patellofemoral osteoarthritis (PFOA) are often considered as a contraindication of medial UKA. 337 fixed bearing UKAs were retrospectively recruited in our joint center between January 1, 2011 and June 30, 2020. There were 105 patients accompanied by PFOA and 232 patients have normal PF joint. International Cartilage Repair Society (ICRS) system was introduced to quantify the degeneration degree of PF joint. Oxford Knee Score (OKS), Forgotten Joint Score (FJS), Kellgren-Lawrence (K-L) classifying system and visual analogue scale (VAS) were adopted to evaluate outcomes between with and without PFOA. There was no significant difference of age, BMI, gender, OKS, FJS and other variables between PFOA and Non-PFOA group. After more than 5 years follow-up, UKA patients with or without PFOA could all achieve a satisfactory improvement of OKS, VAS and FJS score. ROM of the replaced knee increased from preoperative 110° to 130°. 74.3% (78/105) and 75.0% (174/232) patients have no change of K-L grade in PFOA and Non-PFOA group, OKS, FJS, VAS score and ROM were also comparable in all patients and no significant outcomes difference were found between two group. The presence of patellofemoral joint osteoarthritis and anterior knee pain should not be considered to be contraindications to medial fixed-bearing UKA.     

腰膝协同中医外治技术治疗膝骨关节炎的临床疗效

目的 观察腰膝协同中医外治技术治疗膝骨关节炎(knee osteoarthritis,KOA)的临床疗效.方法 纳入60例KOA病人,随机分为腰膝协同用药组、腰部用药组、膝部用药组并给予相应治疗.采用西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、VAS评价3组关节疼痛、肿胀、功能障碍的改善情况,并进行比较.结果 ...     

风湿性二尖瓣病变行二尖瓣成形术的效果分析

目的 探讨风湿性二尖瓣病变行二尖瓣成形术的临床效果。 方法 选取2016年1月至2020年1月在郑州大学第一附属医院心外科因风湿性二尖瓣病变治疗的133例患者为研究对象。其中46例患者行二尖瓣成形术（观察组）,87例患者行二尖瓣置换术（对照组）。观察组中男性10例,女性36例,平均年龄（53.80±8.87）岁;对照组中男性25例,女性62例,平均年龄（56.54±9.88）岁。收集两组患者的基线资料、术前超声结果、围手术期资料、随访资料（术后6个月）,分析二尖瓣成形术的临床效果。 结果 观察组的主动脉阻断时间、体外循环时间、住院时间与对照组相比,差异无统计学意义（P > 0.05）。观察组术后呼吸机辅助时间较对照组短[（9.4±1.6）h比（12.9±1.5）h],差异有统计学意义（P < 0.05）。观察组与对照组术后 6个月左房内径[（41.00±8.00）mm比（46.75±10.13）mm]、左室舒张末期内径[（45.49±5.90）mm比（47.87±5.66）mm]差异有统计学意义,且观察组小于对照组（P < 0.05）。 结论 二尖瓣成形术治疗风湿性二尖瓣病变的早期临床效果满意,有利于心脏重构,值得临床推广应用。     

Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: data from the Osteoarthritis Initiative

Objective

To evaluate the association of magnetic resonance imaging (MRI)–based knee cartilage T2 measurements and focal knee lesions with knee pain in knees without radiographic osteoarthritis (OA) among subjects with OA risk factors.

Methods

We studied the right knees of 126 subjects from the Osteoarthritis Initiative database. We randomly selected 42 subjects ages 45–55 years with OA risk factors, right knee pain (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC] pain score ≥5), no left knee pain (WOMAC pain score 0), and no radiographic OA (Kellgren/Lawrence [K/L] score ≤1) in the right knee. We also selected 2 comparison groups: 42 subjects without knee pain in either knee and 42 with bilateral knee pain. Both groups were frequency matched to subjects with right knee pain only by sex, age, body mass index, and K/L score. All of the subjects underwent 3T MRI of the right knee. Focal knee lesions were assessed and cartilage T2 measurements were performed.

Results

Prevalences of meniscal, bone marrow, and ligamentous lesions and joint effusion were not significantly different between the groups (P > 0.05), while cartilage lesions were more frequent in subjects with right knee pain only compared to subjects without knee pain (P < 0.05). T2 values averaged over all of the compartments were similar in subjects with right knee pain only (mean ± SD 34.4 ± 1.8 msec) and in subjects with bilateral knee pain (mean ± SD 34.7 ± 4.7 msec), but were significantly higher compared to subjects without knee pain (mean ± SD 32.4 ± 1.8 msec; P < 0.05).

Conclusion

These results suggest that elevated cartilage T2 values are associated with findings of pain in the early phase of OA, whereas among morphologic knee abnormalities only knee cartilage lesions are significantly associated with knee pain status.     

体验式营养教育对维持性血液透析患者营养状况的影响

目的研究体验式营养教育是否可改善维持性血液透析(MHD)患者营养状况。方法入选2017年1月至12月宜宾市第二中医院内一科进行维持性血液透析患者180例,随机数表法分为干预组和对照组,每组90例。分别采取传统和体验式营养教育进行干预,6个月后比较2组患者营养知识-态度-行为(KAP)评分、营养相关生化指标和体格测量指标,并采用患者自评-主观全面评定(PG-SGA)量表评估患者整体营养状况。采用SPSS 19.0统计软件对数据进行分析。结果 2组患者年龄、性别、透析时间、原发疾病等差异无统计学意义(P0.05)。干预后干预组相比对照组患者知识评分[(8.5±1.3)和(6.7±2.0)分]、行为评分[(4.1±1.0)和(3.4±1.3)分]、血红蛋白[(106.4±9.2)和(96.1±8.7)g/L]、白蛋白[(38.3±5.2)和(36.2±4.9)g/L]、肱三头肌皮褶厚度[(6.1±2.1)和(5.4±1.9)mm]、上臂围[(26.0±4.4)和(24.5±4.1)cm]、上臂肌围[(24.1±2.6)和(22.8±2.9)cm]、体脂比[(22.6±4.1)%和(21.1±4.4)%]水平均高,差异均具有统计学意义(P0.05)。干预前2组患者PG-SGA评分[(6.1±2.2)和(6.3±2.4)分]差异无统计学意义(P0.05)。干预后干预组PG-SGA评分低于对照组[(4.5±2.0)和(5.6±2.1)分],差异具有统计学意义(t=3.60,P0.05)。干预后对照组营养状况A分级27%(24/90),干预组营养状况A分级40%(36/90),干预组明显高于对照组,差异具有统计学意义(P0.05)。结论体验式营养教育可改善MHD患者营养知识、态度和行为,提高患者饮食依从性,改善患者营养状况。     

In‐patient rehabilitation in haemophilic subjects with total knee arthroplasty

Summary. Total knee arthroplasty (TKA) is a major orthopaedic surgery intervention, indicated for severe haemophilic arthropathy. The aim of our study was to analyse rehabilitation outcome in haemophilic patients after TKA. A consecutive series of 21 patients (23 knees) was retrospectively evaluated. The mean age was 37 ± 8 years (range 22–55). Physiotherapy treatment was performed twice a day for 5 days week^?1, for 3 h day^?1. Assessment included knee range of motion (ROM), Visual Analogue Scale (VAS) for pain evaluation, Western Ontario and McMaster University (WOMAC) Score for functional outcome, Medical Research Council Scale (MRC) for quadriceps muscle strength evaluation, incidence of adverse events and a self‐reported questionnaire. The patients’data were recorded before surgery (t0), at Rehabilitation Unit admission (t1), before discharge (t2) and at follow‐up (t3), 11–48 months after rehabilitation. Western Ontario and McMaster University Score (ref. score: 0–96) was 56.7 ± 12 at t0 and 6.2 ± 6 at t3 (t3 vs. t0: P < 0.001). Visual Analogue Scale (ref. score: 0–10) decreased from 5.0 ± 2 at t1 to 2.1 ± 2 at t2 (t2 vs. t1: P < 0.05) and to 0.1 ± 0 at t3 (t3 vs. t2: P < 0.05). Flexion degrees increased from 43.4 ± 21° at t1 to 80.2 ± 15° at t2 (t2 vs. t1: P < 0.001) and to 95.0 ± 15° at t3 (t3 vs t2: P < 0.05). According to MRC (ref. score: 0–5), quadriceps muscle strength increased from 2.3 ± 0.6 at t1 to 3.6 ± 0.5 at t2 (t2 vs. t1: P < 0.05). Adverse events were found in four patients. Patients’ satisfaction on their outcome at follow‐up was referred as good by 72% of patients or excellent by 28% of patients. Postsurgical intensive rehabilitation in haemophilic patients resulted effective, safe and feasible.     

Diacerein as adjuvant to diclofenac sodium in osteoarthritis knee

Aim: To evaluate clinical effectiveness of diacerein as an adjuvant to diclofenac sodium in treatment of Indian patients with symptomatic osteoarthritis (OA) knee. Methods: This is a prospective, double‐blind, placebo‐controlled and intention‐to‐treat study. An initial washout period of 1 week, was followed by 3 months treatment period during which patients were randomly divided to receive either capsule diacerein 50 mg or matched placebo once daily for the first month and twice daily for the next 2 months with diclofenac sodium 75 mg sustained release tablet once daily given to both groups. Patients were observed for one more month, using paracetamol as rescue therapy. Treatment efficacy was assessed by a visual analogue scale (VAS) and the Western Ontario and McMaster University (WOMAC) Osteoarthritis Index, patient and physician global assessment of OA, daily paracetamol intake. Results: Of 84 patients screened, 74 patients formed the intent‐to‐treat population (37 patients in each group). At baseline, both groups were comparable and at the third month functional index and pain intensity were better in the diacerein group (VAS 15.33 ± 5.07; WOMAC 15.9 ± 2.40) as compared to the placebo group (VAS 22.83 ± 6.90;WOMAC 36.8 ± 2.92; P < 0.05). When analyzed at the fourth month, improvement persisted in the iacerein group (VAS 14.83 ± 5.16; WOMAC 16 ± 2.5) as compared to placebo group (VAS 33 ± 7.72; WOMAC 48.26 ± 3.5; P < 0.05), demonstrating the carry‐over effect of diacerein, which was confirmed by lesser paracetamol consumption in the diacerein group (5.967 ± 0.8087) as compared to the placebo group (12.433 ± 2.128; P < 0.05). Conclusion: Use of diacerein and diclofenac sodium together decreases pain and improves joint function significantly more than diclofenac alone in OA knee.     

Effect of balneotherapy on temporospatial gait characteristics of patients with osteoarthritis of the knee

Effects of balneotherapy on gait properties of patients with osteoarthritis of the knee were investigated prospectively. A total of 30 patients with knee osteoarthritis received balneotherapy consisting of two daily thermomineral water baths for 2 weeks. Patients were evaluated using gait analysis and clinical scores, both within 2 weeks, before and after spa treatment. Patients were walking faster in their control analyses (0.81 ± 0.21 to 0.89 ± 0.19 m/s; P = 0.017), with a shorter mean stance time (63.0 ± 3.3 to 61.8 ± 2.5% stride; P = 0.007), an increased cadence (96 ± 13.1 to 100 ± 11.9 steps/min; P = 0.094) and stride length (996 ± 174 to 1,058 ± 142 mm; P = 0.017). Balneotherapy also resulted in a significant decrease in Lequesne knee osteoarthritis index (12.1 ± 3.7 to 10.0 ± 3.3 points; P = 0.003), VAS for pain (58 ± 25 to 33 ± 15; P = 0.0001), VAS for patients’ (56 ± 24 to 29 ± 19; P < 0.001) and investigator’s global assessment (55 ± 20 to 26 ± 15; P < 0.0001) and WOMAC score (2.1 ± 0.7 to 1.6 ± 0.8; P = 0.0004). Balneotherapy has positive effects on gait properties and clinical health quality parameters of patients with knee osteoarthritis in short-term evaluations.