非有机溶剂高聚物萃取法分离测定Al3+、Ca2+、Co2+、Cu2+、Mg2+、Pb2+、Zn2+混合样品中Al3+的研究

「目的」多组分混合物中铝的测定。「方法」在ＫＨ２ＰＯ４－Ｋ２ＨＰＯ４缓冲溶液，聚乙二醇－铬黑Ｔ－硫酸铵体系中，水溶性高聚物对Ａｌ＾３＋、Ｃａ＾２＋、Ｃｏ＾２＋、Ｃｕ＾２＋、Ｍｇ＾２＋、Ｐｂ＾２＋、Ｚｎ＾２＋萃取研究。「结果」在ｐＨ＝８时，Ｃｏ＾２＋、Ｃｕ＾２＋、Ｍｇ＾２＋、Ｚｎ＾２＋被聚乙二醇相完全萃取，Ｃａ＾２＋、Ｐｂ＾２＋被ＨＰＯ４＾２－掩蔽，而Ａｌ＾３＋几乎不被萃取，从而实现了对上述混合离子     

Ethanol may stimulate or inhibit (Na+ + K+)-ATPase, depending upon Na+ and K+ concentrations

The influence of varying the ratios of [Na+]/[K+] on the effects of alcohol (500 mg/dl) on brain (Na+ + K+)-ATPase, using a commercial porcine enzyme preparation, showed that, generally, activity was stimulated by ethanol when [Na+] less than [K+], but inhibited when [Na+] greater than [K+] (with sum kept constant at 150 mM). In addition, when [Na+]/[K+] was 15/90 mM, representative of normal intracellular levels, ethanol (500 mg/dl) stimulated the porcine enzyme, but inhibited it when [Na+]/[K+] was 144/6 mM, representative of normal extracellular levels. Similarly, in freshly prepared enzyme from highly purified rat brain synaptic membranes, ethanol (100, 300, and 450 mg/dl) stimulated when [Na+]/[K+] was 15/88 mM (representing intracellular levels), but inhibited when [Na+]/[K+] was 142/4 mM (extracellular levels).     

Care = organisation + physical labour + emotional labour

The formula‘care = organisation + physical labour + emotional labour' identifies component parts of ‘carework’ as they were observed at a hospice. A comparison between women's domestic carework and that of the hospice nurses is made firstly to clarify the component elements of care and secondly to show how the interrelation and balance of the components differs in the two settings. It is argued that family care has been a model for hospice care but that division of labour in hospices, which replicates hospital labour-divisions, results in an inflexibility in hospice care which is incompatible with the ‘family’ model. In the final section it is suggested that emotional labour is likely to be increasingly recognised as part of health care but that the concept of ‘total care’ needs to be questioned.     

Regulation of the Renal Na+-H+ Exchanger

Regulation of the activity of this transporter is critical to the overall acid-base economy of the organism. Studies have now elucidated some of the regulatory mechanisms. One important type of regulation is by processes involving protein phosphorylation mediated by specific protein kinases. Some of the intracellular pathways involved in the regulation are described.     

子痫前期患者CD4~+CD25~+Foxp~(3+)调节性T细胞检测及意义

目的:研究CD4+CD25+Foxp3+调节性T细胞在子痫前期患者(PE)外周血中的比例变化,探讨其在子痫前期发病中意义。方法:采用细胞内染色的流式细胞术检测22例子痫前期患者外周血中CD4+CD25high和CD4+CD25+Foxp3+的表达,并与正常妊娠和正常育龄妇女进行比较。结果:子痫前期患者外周血单个核细胞(PBMCS)CD4+T细胞中CD25high细胞明显低于正常妊娠和正常育龄妇女,CD4+CD25+Foxp3+的表达显著降低,而且其CD4+CD25+Foxp3+的表达与平均动脉压呈负相关。结论:子痫前期患者CD4+CD25+Foxp3+的表达明显减少,表明调节性T细胞的降低可能打破了母胎之间的耐受,参与了子痫前期的病理进程。     

Mergers + acquisitions

The hospital sector in 2001 led the health care field in mergers and acquisitions. Most deals involved a network augmenting its presence within a specific region or in a market adjacent to its primary service area. Analysts expect M&A activity to increase in 2002.     

Medicare+Choice

Created five years ago out of the Balanced Budget Act, Medicare+Choice was thought to be the next generation of Medicare, giving benefits to seniors and saving the government money. But enrollment has dropped and health plans, complaining of low reimbursement rates, have fled. What went wrong? Can it be fixed?     

就医指南

三枚支架疏通下腔静脉栓塞;输尿管镜气压弹道碎石;新的子宫颈癌根治术;多靶点治疗可延长肝癌患者生存期;糖尿病足治疗有方.     

就医指南

上颌骨缺失新疗法上颌骨位于面中部,对于面部的功能和美观起着举足轻重的作用。由于外伤、肿瘤切除、先天畸形等原因造成的上颌骨缺失是颌面部骨缺损中最严重类型,给患者造成极大痛苦。上颌骨全部缺失后,缺损腔巨大,骨骼丧失,只余留薄弱的黏膜。以传统办法进行修复时,由于缺乏足够的骨骼支撑,患者面中部塌陷状况不能得到根本性改善,严重者会出现"没脸"的状况。更不利的是,安装的义齿由于上方缺乏有效支持和固位.不能有效承力且容易脱落,难以正常咀嚼食物,严重者只能吞食食物。另外,患者还会伴随发音不清、吞咽困难。因此,如何实现上颌骨缺失患者面型及咀嚼、发音、吞咽等功能的有效重建,     

Project 67+

Project 67+ is carried out in Oslo, the capital city of Norway.Oslo has 450 000 inhabitants, and was once known in health-circlesfor the ‘Oslobreakfast’. Project 67+ is a campaignwhich sets out to change attitudes towards the elderly amongthe public in general and also the elderly and their attitudetowards ageing. The major part of the work is done by the elderlythemselves. It has proved to be a movement that is here to stay,and it is continuously developing in new directions. On 1 July 1988 Oslo Municipality inaugurated a system of 25local Neighbourhood Administrative Schemes. These urban schemesare to administer all municipal health and social services,with the exception of specialist services and hospitals. Thishas caused a lot of changes, however, but will also give opportunities,not least to create an influence on local politics, etc.     

就医指南

颅内电极埋藏技术诊治癫痫 李女士患癫痫病已达18年之久.在国内多家医院诊治并服用了大剂量抗癫痫药物后,仍难以控制病情.     

2,3,7,8-四氯二苯并二噁英急性染毒对小鼠脑组织中Na+-K+-ATP酶和Ca2+-ATP酶活力的影响

目的 研究2,3,7,8-四氯二苯并二噁英(TCDD)对小鼠脑组织中Na+-K+-ATP酶、Ca2+-ATP酶活力的影响.方法 将48只雌雄各半的昆明种小鼠按性别随机分为高、中、低剂量TCDD染毒组和对照组,每组雌雄各6只,TCDD染毒剂量分别为100、10、1 μg/kg,用腹腔注射的方式一次染毒,48 h后,测定脑组织中Na+-K+-ATP酶、Ca2+-ArrP酶活力.结果 雌性低剂量、中剂量染毒组和雄性高剂量染毒组小鼠脑组织中Na+-K+-ATP酶活力[分别为(17.35±3.07)、(16.13±2.42)、(20.25±2.72)μmolPi·mg pro-1·h-1]明显升高,与对照组[分别为(13.60±1.72)、(15.97±1.90) μmol Pi·mg pro-1·h-1相比,差异均有统计学意义(P<0.05).各染毒组小鼠Ca2+-ATP酶活力有增加的趋势,但与对照组比较,差异无统计学意义(P>0.05).结论 TCDD急性染毒能提高小鼠脑组织中Na+-K+-ATP酶的活力,且存在性别差异.     

支气管哮喘患儿CD4~+CD25~+Foxp3~+IL-10~+ T淋巴细胞水平变化和意义

目的:探讨对尘螨过敏的轻度持续支气管哮喘患儿淋巴细胞增殖情况及CD4+CD25+Foxp3+IL-10+ T淋巴细胞水平变化。方法:选择30例对尘螨过敏的轻度持续支气管哮喘患儿作为实验组,同时选择30例健康儿童作为对照组。分离所有入选者的外周血淋巴细胞,给予户尘螨浸出液刺激48 h后检测淋巴细胞增殖的刺激指数以及CD4+CD25+Foxp3+IL-10+ T淋巴细胞水平变化。结果:支气管哮喘患儿外周血淋巴细胞接受户尘螨浸出液刺激后淋巴细胞增殖的刺激指数显著高于对照组(P<0.01),支气管哮喘患儿CD4+CD25+Foxp3+IL-10+ T淋巴细胞水平显著低于对照组(P<0.01)。结论:支气管哮喘患儿接受过敏原刺激后发生明显的增殖反应,支气管哮喘患儿存在CD4+CD25+Foxp3+IL-10+ T淋巴细胞功能障碍。     

CD4+CD25+T细胞研究新进展

CD4 CD25 T细胞是新近才被认识的一类免疫调节细胞,在胸腺中产生,主要发挥抑制性免疫调节功能,表达IL-10 mRNA,细胞表面表达IL-2受体a链(CD25),在维持机体内环境的稳定、抗感染免疫、抗肿瘤免疫、诱导移植耐受及自身免疫性疾病等方面发挥重要作用。