奥硝唑糊剂治疗慢性根尖周炎的疗效评价

目的 :比较奥硝唑碘仿糊剂和替硝唑碘仿糊剂治疗慢性化脓性根尖周炎的疗效差异。方法 :选择慢性化脓性根尖周炎病例 12 1例 ,随机分成两组。奥硝唑碘仿根管糊剂组为实验组 ,替硝唑碘仿根管糊剂组为对照组。采用二次法治疗并用牙胶尖充填根管 ,记录临床症状和体征 ,6个月后拍摄X线牙片 ,观察根尖阴影变化情况。结果 :实验组临床疗效优于对照组 ,有统计学差异 (P <0 .0 5 )。结论 :奥硝唑碘仿根管糊剂治疗慢性根尖周炎的疗效优于替硝唑碘仿根管糊剂。     

氢氧化钙碘仿糊剂治疗根管封药疼痛的临床观察

目的 评价氢氧化钙碘仿糊剂治疗根管封药后的根尖周炎的疗效。方法 在扩管封药后疼痛的根管内置人氢氧化钙碘仿糊剂棉捻，评价其疗效。结果 37例疼痛消失或减轻，有效率达94．9％。结论 在治疗根管封药后的根尖周炎中，氢氧化钙碘仿糊剂是一种有效的治疗手段。     

2种糊剂对慢性根尖炎患牙侧副根管封闭性的效果比较

目的:观察2 种根管充填糊剂充填慢性根尖炎侧副根管的治疗效果.方法:选择术后X 线片显示有侧副根管的慢性根尖炎病例54 例, 随机分为AH-plus 组和赛普敦组,每组27 例.开髓、揭顶、去除牙本质肩领,应用逐步后退法进行根管预备,氢氧化钙糊剂根管封药消毒,分别选用AH-plus 糊剂和赛普敦(SEPTODONT)美松根管充填糊剂, 热牙胶连续波垂直加压充填技术进行根管充填.比较根尖1/3侧副根管充填率、治疗一年后根管治疗成功率和感染控制率.结果:AH-plus 组根尖1/3 侧副根管充填率为62.96%,根管治疗成功率为88.89%,感染控制率为96.30%,分别高于赛普敦组的37.04%、66.67% 和74.07%,差异有统计学意义(P<0.05).结论:AH-plus 糊剂较赛普敦美松糊剂对侧副根管充填的疗效好.     

改良奥硝唑碘仿糊剂与碧兰糊剂的临床效果比较

目的：比较改良奥硝唑碘仿糊剂与碧兰糊剂的临床疗效。方法：选择临床394例需要根管治疗的牙髓病或根尖周病患者，年龄13～65岁，随机分为两组，根管治疗中分别以改良奥硝唑碘仿糊利和碧兰糊剂进行根管充填。结果：根管允填后于1周复诊。实验组和对照组治疗成功率分别为93．5％和95．4％；1年复诊，通过临床和X线检查，两组治疗成功率分别为91％和93．3％。结论：改良奥硝唑碘仿糊剂与碧兰糊剂比较，临床疗效无显著性差异，其复合组方成本低廉，安全可靠，疗效确切。     

METAPEX糊剂预防乳牙一次性根管治疗术后急诊的效果评价

目的:评价METAPEX糊剂-氢氧化钙碘仿糊剂用于乳牙一次性根管治疗术后急诊的效果.方法:选择178例238颗需要进行根管治疗的乳磨牙,随机分为2组,实验组采用METAPEX糊剂一次性根管充填,对照组采用氧化锌丁香油糊剂治疗.采用SPSS14.0软件包对数据进行X2检验.结果:METAPEX糊剂组急症发生率明显低于氧化锌丁香油糊剂组,具有显著性差异.结论:METAPEX糊剂能有效降低乳牙一次性根管治疗术后急诊的发生.     

牙髓病及根尖周病

不同根管糊剂在根管治疗一次法中临床疗效比较;派丽奥治疗慢性根尖周炎临床疗效观察;氢氧化钙碘仿糊剂与干髓糊剂治疗乳牙尖周炎的临床比较研究;Hero 642根管预备系统在弯曲根管应用中的比较研究;ProPex测量仪对磨牙根管工作长度准确性的临床评价     

复方氢氧化钙糊剂治疗乳牙根尖周炎的疗效评价

目的 应用灭滴灵、碘仿、氢氧化钙复方糊剂配成根管充填剂，治疗乳牙根尖周炎，评价其在治疗乳牙根尖周炎中的疗效。方法 随机将301个乳牙分为两组：实验组用复方根管充填糊剂，对照组用氧化锌丁香油糊剂进行根管充填。结果 复方根管充填糊剂组的成功率高于对照组，且患儿易配合。结论 复方糊剂较常规氧化锌丁香油糊剂充填根管具有更好的临床疗效。     

替硝唑碘仿根管糊剂治疗慢性根尖周炎伴异位窦道的疗效评价

目的 比较替硝唑碘仿根管糊剂和甲硝唑碘仿根管糊剂在治疗慢性化脓性根尖周炎伴异位窦道疗效上的差异。方法 选择慢性化脓性根尖周炎伴异位窦道的患者127例，随机分为2组，替硝唑碘仿根管糊剂组(实验组)和甲硝唑碘仿根管糊剂(对照组)。应用两次法与牙胶尖充填根管，记录临床症状和体征，6月后拍摄X线片，观察根尖阴影是否消失。结果 实验组临床疗效优于对照组，且有统计学差异(P＜0．05)。结论 替硝唑碘仿根管糊剂在治疗慢性化脓性根尖周炎伴异位窦道的疗效优于甲硝唑碘仿根管糊剂。     

氢氧化钙碘仿糊剂用于乳牙感染根管消毒的疗效观察

目的：观察氢氧化钙碘仿糊剂用于乳牙感染根管消毒的临床疗效。方法：272个患牙随机分成两组,治疗组151个用氢氧化钙碘仿糊剂根管封药,对照组121个用甲醛甲酚根管封药,1周后复查,观察疗效。结果：1周后复查,治疗组临床疗效明显优于对照组。结论：氢氧化钙碘仿糊剂可抑制细菌的生长,诱导根尖周组织矿化修复,有益于保护继承恒牙胚,用于乳牙感染根管消毒疗效好。     

AH Plus与CCQ碘仿糊剂根管充填的疗效比较

目的比较AHPlus糊剂加牙胶尖、CCQ碘仿糊剂加牙胶尖充填根管后的患牙疼痛反应和疗效。方法将300颗患牙随机分为AHPlus糊剂组和CCQ碘仿糊剂组,在行常规根管治疗术的基础上分别采用AHPlus糊剂加牙胶尖和CCQ碘仿糊剂加牙胶尖充填根管,观察术后1周内患牙疼痛发生情况以及术后12个月的疗效。结果疼痛发生率AHPlus糊剂组术后较CCQ碘仿糊剂组低,差异有统计学意义(P<0.05);术后12个月疗效,AHPlus糊剂组高于CCQ碘仿糊剂组,差异有统计学意义(P<0.05)。结论AHPlus糊剂加牙胶尖充填根管可有效降低术后患牙的疼痛反应,与CCQ碘仿糊剂加牙胶尖比较,远期疗效有意义。     

冠桥修复对根管糊剂超填基牙疗效的影响

目的评价冠桥修复对根管糊剂超填的基牙疗效影响。方法慢性根尖周炎患牙用自配根管糊剂行一次法根管治疗术将超填的165颗患牙分为2组,基牙组91颗,非基牙组74颗,治疗后6、12、24个月随访,经临床检查和X线片检查,比较2组治愈率和超填糊剂残留率。结果治疗24个月,基牙组71颗痊愈,治愈率78.02%;非基牙组61颗痊愈,治愈率82.43%。基牙组45颗超填糊剂残留,残留率49.45%;非基牙组38颗超填糊剂残留,残留率51.35%。2组治愈率和超填糊剂残留率差异无统计学意义(P>0.05)。结论冠桥修复对根管糊剂超填的基牙疗效无影响。     

两种根充糊剂治疗乳牙根尖周炎的疗效观察

目的观察Vitapex糊剂与氧化锌丁香油糊剂应用于乳牙根充的临床疗效。方法选择186例乳牙患急、慢性根尖周炎病例,随机分为观察组(Vitapex)和对照组(氧化锌丁香油糊剂)各93例,观察根管充填后临床疗效。结果两组根充后根尖反应程度和治疗效果差异有显著性。观察组根充反应程度(6.48%)低于对照组(10.58%),根充成功率观察组(87.04%)高于对照组(74.04%)。结论采用Vitapex糊剂作为乳牙根尖周炎治疗后的充填药物,治愈成功率优于传统的根充药物。     

An investigation into the effect of denture adhesives on incisal bite force of complete denture wearers using pressure transducers - a clinical study

PURPOSE

Study was conducted to determine and assess the effect of different type of denture adhesives on the incisal bite force of complete denture wearers until the dislodgement of upper denture, using pressure transducer.

MATERIALS AND METHODS

30 patients out of 100 were included in the study. Based on the Kapur''s method of scoring denture retention and stability, these patients were divided into 3 groups- Group A - Clinically good dentures; Group B - Clinically fair dentures; and Group C - Clinically poor dentures. A custom made occlusal force meter was constructed based on the load cell type of pressure transducers. Different adhesives (powder, paste and adhesive strips) were used in the study. Complete denture wearers were asked to bite on the load cell and the readings of incisal bite force were recorded. The readings of incisal bite force were subjected to statistical analysis using Repeated measures ANOVA followed by post-hoc bonferroni test.

RESULTS

The result suggests that denture adhesives improved the incisal bite force of complete denture wearers significantly The incisal bite force (in kg) in Group A without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 2.48 (± 0.16), 3.43 (± 0.11), 6.01 (± 0.11), 3.22 (± 0.09) respectively. The incisal bite force (in kg) in Group B without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 1.87 (± 0.18), 3.35 (± 0.14), 5.34 (± 0.18), 3.21 (± 0.12) respectively. The incisal bite force (in kg) in Group C without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 1.00 (± 0.17), 3.07 (± 0.14), 4.37 (± 0.26), 2.99 (± 0.14) respectively.

CONCLUSION

Within the limitations of the study, it was concluded that the use of denture adhesive was found to be significantly effective in improving the incisal bite force of complete dentures until the dislodgement of upper denture. Fittydent paste adhesive was found to be more effective than the powder and strips adhesives. The improvement in incisal bite force was found to be higher in Group C in comparison to that of Group A and Group B.     

2种充填剂治疗乳牙根尖周炎的疗效观察

目的:总结分析179例患儿283颗窦道型乳牙根尖周炎患牙的治疗效果。方法:选择283颗乳牙慢性根尖周炎伴窦道的患牙,196颗用氧化锌丁香油糊剂充填,87颗用Vitapex充填。分别于治疗后3个月和1a复查自觉症状、临床体征及X线表现。结果:两组不同药物根充的根管治疗疗效于治疗3个月和1a时复查,成功率均在96.0%以上。结论:乳牙窦道型根尖周炎只要适应证选择恰当,及时做根管治疗,大部分患牙均可予以保留。     

Oral implants placed in bone defects treated with Bio‐Oss®, Ostim®‐Paste or PerioGlas: an experimental study in the rabbit tibiae

Objectives: To compare the histological features of bone filled with Bio‐Oss^®, Ostim‐Paste^® or PerioGlas placed in defects in the rabbit tibiae by evaluating bone tissue composition and the integration of titanium implants placed in the grafted bone. Material and methods: Two cylindrical bone defects, about 4 mm in diameter and 6 mm in depth, were created in the tibiae of 10 rabbits. The defects were filled with either Bio‐Oss^®, PerioGlas, Ostim^®‐Paste or left untreated, and covered with a collagen membrane. Six weeks later, one titanium sandblasted and acid‐etched (SLA) implant was inserted at the centre of each previously created defect. The animals were sacrificed after 6 weeks of healing. Results: Implants placed in bone previously grafted with Bio‐Oss^®, PerioGlas or Ostim^®‐Paste obtained a larger extent of osseointegration, although not statistically significant, than implants placed in non‐grafted bone. The three grafting materials seemed to perform in a similar way concerning their contribution towards implant osseointegration. All grafting materials appeared to be osteoconductive, thus leading to the formation of bridges of mineralized bone extending from the cortical plate towards the implants surface through the graft scaffold. Conclusions: Grafting with the above‐mentioned biomaterials did not add any advantage to the osseointegration of titanium SLA implants in a self‐contained defect.     

根管侧壁穿孔的修补及桩冠的临床探索

对２０例，２１个有根壁侧穿，并伴有根周脓肿或窦道的患牙，重新进行根管清理、预备、消毒，达到根充指征时，即采用氢氧化钙加碘仿糊剂修补侧壁穿孔，同时加牙胶尖进行根充，３～４周后，采用铸造基底背板桩行桩冠修复患牙，取得了较为满意的效果。     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.