说"魂"话"魄"

“魂”与“魄”虽皆可用以表示精神、神志等，但就本义而言，有“阴”与“阳”之分。中医学中与之相关的许多名词术语及理念，既发端于先民对“魂”、“魄”不同初始义的认识，又促进了其词义的外延。     

释"营"与"荣"

对中医的“营”、“荣”二字，从词义引申与语言文化角度进行阐释．说明了二者的区别与联系，并探讨所涉及的医理。     

从"神"论治"石"

五行学说认为世界是物质的,宇宙世界是由木、火、土、金、水五种基本物质所构成的.人体身体健康,气化功能正常,气运行通畅,血与津液流通也通畅,精气充足,生理活动正常,生命力旺盛,叫有"神".如果五脏不调和,精气生成不足,循行不调和,必生凝滞,"石"乃产生.五脏六腑以通为用,五脏六腑条达,气血流通.人即有神,石乃自出.     

"肾主骨"与"肾主外"刍议

从《黄帝内经》原文及相关文献的角度,探讨“肾主骨”与“肾主外”的关系,得出重要结论;“肾主外”虽有多种意义,但“肾主骨”是最符合原意的。     

浅析"整体观"与"整体护理"

“整体观”是中医基础理论的核心,是辨证施护的指导思想;“整体护理”是在整体观的理论指导下的具体实施。但无论是整体观还是整体护理,其实质都是对人的健康实施全面的护理,充分体现了人性化的护理及人文关怀。整体观与整体护理的理论有着相似之处。     

浅谈"传"经、"经尽"、"再经"、"过经"揭示的辨证意义

从《伤寒论》中反映外感病发展的病机、病势且具有辨证意义的原文入手,探讨“传”经、“经尽”、“再经”、“过经”的内涵及辨证意义。结论:(1)“传”经,提示邪气波及或递转他经。前者指部分邪气内传他经;后者指邪气离表而尽转他经。(2)“经尽”,寓示病势转归的两种形式。一是指邪离本经而转入下一经的趋势,即“再经”;二是指邪气尽离本经而转愈的趋势,即“经不传”。(3)“过经”有两种情形:一为由表入里而病进;二为由阴转阳而病退。前者泛指疾病发展到某一阶段时的病性转变;后者指病由太阴转入阳明而转愈。     

羊涤生中国文化的"公"、"立德"与"和"

“观于海者，难为水。游于圣人之门者，难于言。”上面是孟子的喟叹，不论是观象、观变、观物、观生或观心．中国人的思维绕不开拥有超拔的儒家精神，今中见古，吉中示令。     

论中风"血瘀髓海"与"活血化瘀"

中风是卒然昏倒,不省人事,伴口眼(喁)斜、半身不遂,或不经昏仆而仅以半身不遂、口眼(喁)斜为主症的一种疾病.本病起病急骤,证见多端,变化迅速,与自然界风性善行数变特征相似,故古代医家从广义上认识该病,遂类比名中风.又因发病突然而称"卒中".     

论"精确处方"与"模糊处方"

药物与药物合用之后可能发生的关系,称为"药际关系",这种关系是客观存在,而配伍则具有主观性。要使配伍的主观愿望得以实现,必须使药物符合"好的药际关系"。经方、时方产生的根源正在于是否符合"特别好的药际关系"。在此基础上,可由含糊的经方、时方的概念,推出"精确处方"与"模糊处方"的新概念。由此,方剂大致可区分为两大类,这样的区分,使方剂学教学和方剂学研究今后可以向着两个不同的方向发展,而临床运用方剂也可以按不同的思路进行。     

"苦杏仁"更名为"杏仁"的商榷

通过考释“苦杏仁”与“杏仁”的源流,发现现代有关中药著作及《药典》中“苦杏仁”既未遵照古代主要本草命名传统,也未参考临床用药习惯,其命名欠妥,建议应以“杏仁”作为正名。     

Effects of Penta‐O‐galloyl‐β‐D‐glucose on Human Neutrophil Function: significant Down‐Regulation of L‐selectin Expression

Penta‐O‐galloyl‐β‐D‐glucose (PGG) occurrs in high concentrations in medicinal herbs such as Rhus chinensis, Paeonia suffruticosa, Acer truncatum and Terminalia chebula, which demonstrate anti‐inflammatory activity. We investigated the effect of PGG on stimulated and non‐stimulated neutrophils in processes which included reactive oxygen species generation (ROS), metalloproteinase‐9 and interleukin‐8 secretion (IL‐8), β₂ integrin (CD11b) and L‐selectin (CD62L) expression and apoptosis. In concentrations of 5 μM–20 μM, PGG demonstrated statistically significant inhibition of ROS generation, IL‐8 secretion and β₂ integrin expression in stimulated neutrophils. The inhibition of L‐selectin expression by PGG resulted in prevention in neutrophils’ endothelial attachment. The result obtained may explain the anti‐inflammatory activity of this compound and underline the contribution of PGG in the activity of PGG rich plant extracts. Copyright © 2012 John Wiley & Sons, Ltd.     

Anti‐inflammatory activity of Rhodiola rosea – “a second‐generation adaptogen”

Rhodiola rosea (golden root), a unique phytoadaptogen grown in high‐altitude regions has gained attention for its various therapeutic properties. In India, this plant is found in the Himalayan belt and has not been completely explored for its beneficial health effects. The present study was undertaken to evaluate the anti‐inflammatory efficacy of the tincture extract of Rhodiola rosea roots (RTE). The anti‐inflammatory activity was determined through carrageenan‐induced paw oedema, formaldehyde‐induced arthritis and nystatin‐induced paw oedema in rat model. The tincture extract exhibited inhibitory effect against acute and subacute inflammation at a dose of 250 mg/kg body weight. Inhibition of nystatin‐induced oedema was also observed in a dose‐dependent manner. The in vitro inhibitory effects of the tincture extract from R. rosea roots was evaluated against the enzymes relating to inflammation. The enzymes include cyclooxygenase‐1 (COX‐1), cyclooxygenase‐2 (COX‐2) and Phospholipase A₂ (PLA₂). The extract showed varying inhibitory activities against these enzymes depending on the concentrations. A potent inhibition was observed against Cox‐2 and PLA₂. Inhibition of nystatin induced oedema and phospholipase A₂ suggested that membrane stabilization could be the most probable mechanism of action of RTE in anti‐inflammation. The findings in this study may provide the use of R. rosea root extract in the treatment of inflammatory conditions. Copyright © 2009 John Wiley & Sons, Ltd.     

阿胶生产工艺中胶原蛋白降解过程研究

目的:研究阿胶生产工艺中胶原蛋白的降解过程以及关键单元操作.方法:在阿胶生产过程中取样并分析其氨基酸组成和相对分子质量范围,利用高效液相色谱质谱技术分析其多肽组成.结果:阿胶生产工艺中原料胶中甘氨酸含量提高了16.8%,表明原料胶中胶原蛋白含量逐渐升高;凝胶过滤色谱分析结果表明原料胶相对分子质量逐渐降低,胶原蛋白的降解过程主要集中在常压浓缩阶段;质谱分析结果表明原料胶内除胶原蛋白外还存在细胞外基质蛋白和部分细胞骨架蛋白的降解物,在常压浓缩过程中以泡沫形式被去除的物质主要为非胶原类蛋白的降解物.结论:阿胶生产工艺中胶原蛋白的降解过程主要集中在常压浓缩阶段,常压浓缩过程是影响阿胶产品组成的关键单元操作.