原发性精囊癌1例报道并文献复习

目的 探讨原发性精囊癌的诊治方法.方法 分析收治的原发性精囊癌1例,结合文献进行复习.结果 经CT、MRI及经直肠超声(transrectal ultrasound,TRUS)引导下穿刺活检确诊为精囊腺癌,行左侧精囊肿物切除、右侧精囊切除、膀胱与前列腺部分切除及左输尿管膀胱再吻合术,术后恢复良好.现已随访23个月,未见复发转移.结论 原发性精囊癌临床罕见,术前诊断较为困难,TRUS引导下穿刺活检可明确诊断,应根据患者个体情况选择不同的根治性切除术.术后定期随访,注意是否复发转移.     

原发性精囊透明性细胞癌1例报告并文献复习

目的:探讨原发性精囊透明细胞癌的临床表现、病理特征及诊断治疗。方法:对我院收治的1例原发性精囊透明细胞癌患者的临床资料进行回顾分析,并复习相关文献。结果:本例患者因反复血精2年入院,术前经影像学及精囊镜活检证实为右侧精囊原发透明细胞癌,免疫组织化学检查示PSA-,CK7-,CD125-,CD20-,RCC+,CD10+,EMA+,行开放性膀胱前列腺精囊切除术、盆腔淋巴结清扫术及回肠膀胱术。术后随访1年,未见肿瘤复发及肾脏占位病变。结论:原发性精囊癌病理分型为透明细胞癌类型极为罕见,手术为其主要治疗方法,需达到肿瘤切缘阴性,术后是否行抗雄激素治疗或放化疗等辅助治疗尚存在争议。     

应用Da Vinci机器人治疗精囊原发性恶性肿瘤的临床效果观察

目的:探讨应用Da Vinci机器人治疗精囊原发性恶性肿瘤的临床效果。方法:回顾性分析2013年1月~2016年8月解放军总医院应用Da Vinci机器人实施的4例精囊原发性恶性肿瘤手术患者的临床资料。结果:4例患者中,2例实施精囊肿瘤切除术,2例实施膀胱、前列腺、精囊切除术,其中1例术前发现盆腔淋巴结转移患者同时实施了盆腔淋巴结清扫术。4例手术均获成功,术中无直肠、大血管损伤等严重并发症。手术时间50~180min,术中失血量50~300ml。精囊肿瘤切除患者术后5天出院,膀胱、前列腺、精囊切除患者分别于术后7天和11天出院。术后病理回报,2例精囊腺癌,1例精囊未分化癌,1例精囊肉瘤。随访6个月~2年,2例精囊腺癌均无瘤存活。1例精囊未分化癌于术后1年发现局部复发,1例精囊肉瘤在术后6个月因肿瘤多发转移死亡。结论:精囊原发性恶性肿瘤恶性度高,手术操作难度较大。Da Vinci机器人操作精巧灵活,便于术野和肿瘤显露,应用于精囊原发性恶性肿瘤的手术效果良好。     

原发性精囊恶性肿瘤的诊断及治疗(附3例报告)

目的 探讨原发性精囊恶性肿瘤的诊断及治疗方法。方法 回顾分析了3例原发性精囊恶性肿瘤的症状、体征、检查结果及手术方案，并对患者进行随访，总结了原发性精囊恶性肿瘤诊断及治疗特点。结果 1例行双侧精囊连同膀胱、前列腺、直肠（全盆腔切除术）根治性切除术，2例行精囊肿瘤、膀胱部分、前列腺部分切除术，2例术后随访5年内无复发和转移，1例术后至今（3个月）未复发。结论 原发性精囊恶性肿瘤初期症状不明显，早期诊断困难，容易误诊，但是临床工作中注意该病的存在，可提高诊断率。手术是本病的基本治疗措施，可根据肿瘤的范围、周围器官受累情况选择手术范围。     

肾透明细胞癌精囊转移一例报告

转移性精囊癌临床少见,肾透明细胞癌转移至精囊腺的病例在临床中更加罕见,在临床工作中难以与膀胱、前列腺和直肠肿瘤相鉴别。2017年11月潍坊市人民医院收治1例肾透明细胞癌转移至左侧精囊腺患者,应用腹腔镜技术切除精囊转移肿瘤。术后规律行膀胱灌注及口服舒尼替尼治疗,随访19个月,精囊及周围组织未见肿瘤复发。     

原发性膀胱小细胞癌3例的诊断和治疗

目的 认识原发性膀胱小细胞癌的发病和临床特点,提高对该病的诊治水平。方法 分析3例原发性膀胱小细胞癌患者的临床资料,结合文献对该病的病理学及临床特征、诊断、治疗和预后进行讨论。结果本组原发性膀胱小细胞癌3例,其中2例经手术、1便经膀胱镜下活检病理证实为膀胱小细胞癌。1例T_4M_1经化疗三月后死亡,1例T_(3a)M_0行膀胱部分切除术,术后予以化疗,一年后死于心梗,1例T_4M_0行根治性膀胱切除术,术后予以放疗,仍在随访中,无复发及转移。结论 原发性膀胱小细胞癌系高度恶性肿瘤,其治疗方式是根治性膀胱切除术辅以术后放疗,化疗疗效尚不肯定。     

原发性精囊癌2例诊治分析

目的探讨原发性精囊腺癌的临床表现、影像学特点及诊治方法。方法分析收治的原发性精囊腺癌患者2例,其中1例合并巨大多分隔精囊囊肿,并结合文献进行复习。结果 1例术前行前列腺穿刺活检阴性,行前列腺电切术后病理证实为偶发癌,2个月后二期行开放前列腺癌根治术后确诊为精囊癌;另一例术前经CT及经直肠超声可见盆腔巨大囊性多分隔肿物,未见正常前列腺及精囊结构,代之以多房囊肿,行腹腔镜下盆腔囊肿切除术,术中冰冻病理诊断为精囊癌,转行开放性前列腺根治术。两例术后恢复良好,分别随访10年及7个月,未见复发转移。结论原发性精囊腺癌临床罕见,术前诊断较困难,影像学表现大致可分为3类,手术为主要治疗方式,切除范围应足够广泛。     

原发性膀胱印戒细胞癌1例报告并文献复习

目的：探讨原发性膀胱印戒细胞癌的临床特征。方法：报告1例原发性膀胱印戒细胞癌患者的临床资料。患者因间歇性肉眼血尿就诊,术前检查未找到任何膀胱外病灶,行膀胱全切除术＋输尿管造瘘术。结果：术后病检报告为膀胱印戒细胞癌。患者术后转肿瘤科化疗,目前正在随访中。结论：原发性膀胱SRCC非常罕见,进展快、恶性程度高,局部浸润性生长,有早期扩散转移倾向,预后差。其确诊主要依靠病理组织学检查。     

前列腺增生并前列腺部尿道癌临床分析

目的探讨原发性前列腺部尿道癌的临床特征及治疗方法。方法对3例前列腺增生合并原发性前列腺部尿道癌患者的临床资料进行回顾性分析。结果 3例患者均表现为排尿不畅并膀胱刺激症状等,术中病理确认后,均行经尿道电切手术,切除肿瘤及前列腺增生组织,其中2例坚持膀胱灌注化疗,分别随访5年和3年6个月,未发现复发和转移,1例未行膀胱灌注化疗,术后10个月发现膀胱肿瘤。结论老年前列腺增生合并前列腺部尿道癌的患者,如肿瘤分级分化较好,行保留器官的肿瘤切除术,术后坚持膀胱灌注化疗,密切随访,是保证患者生活质量的有效治疗方法。     

膀胱内翻性乳头状瘤的诊治

目的：探讨膀胱内翻性乳头状瘤的临床特点、病因、病理和诊断治疗。方法：回顾性分析50例膀胱内翻性乳头状瘤的临床资料,复习相关文献,并随访患者。结果：所有患者均接受经尿道膀胱肿瘤电切术（TURBT）治疗;术后病理证实均为膀胱内翻性乳头状瘤,其中29例合并膀胱移行细胞癌;术后42例行膀胱灌注治疗,随访3个月～5年,1例患者肿瘤复发。结论：膀胱内翻性乳头状瘤是泌尿系少见的良性肿瘤,易合并移行细胞癌,很少复发,预后良好。确诊需行内镜检查及活检。TURBT是其标准治疗方法。术后予膀胱灌注有利于防治复发。     

Primary carcinoma of seminal vesicle. Diagnosis assisted by sonography

A case of primary carcinoma of the seminal vesicle in a nineteen-year-old man is described. This patient represents the twelfth case reported in the literature in Japan. The experience gained in this case indicated the potential usefulness of ultrasonography in the diagnosis of primary carcinoma of the seminal vesicle.     

Primary squamous cell carcinoma of the seminal vesicle

A 69-year-old man with primary squamous cell carcinoma of the seminal vesicle was successfully treated. The patient presented with complaints of gross hematuria and difficulty in urination. Transrectal ultrasonography revealed a cystic mass behind the bladder, and solid tumorous lesions were visualized in the cyst wall by magnetic resonance imaging. The cystic mass was surgically excised and was verified as the enlarged seminal vesicle with concomitant squamous cell carcinoma. The histopathologic diagnosis was squamous cell carcinoma in the seminal vesicle. Postoperatively, 50 Gy of external beam radiation was targeted to the whole pelvic cavity, and the patient was alive without recurrence 2.5 years after surgery. No other neoplasm was discovered in the body.     

Primary extraskeletal osteosarcoma of the seminal vesicle: a case report and literature review

A primary extraskeletal osteosarcoma (EOS) is a rare tumour. An EOS of the seminal vesicle has not been reported in the literature. We describe a case of a seminal vesicle EOS initially detected as a pre-rectal mass on a routine transrectal ultrasound in a 48-year-old man. A computed tomography (CT) scan confirmed the tumour to be arising from the left seminal vesicle. A robot-assisted laparoscopic seminal vesiculectomy was performed to avoid neurovascular bundle injury. Microscopic examination of the resected specimen showed a poorly differentiated osteosarcoma originating from the seminal vesicle. The patient received adjuvant chemotherapy. He is doing well without voiding or erectile dysfunction and he is tumour-free five months after surgery.     

Primary seminal vesicle carcinoma detected at transurethral resection of prostate

We present a case of primary seminal vesicle carcinoma detected at transurethral resection. The clinical presentation, radiologic findings, and pathologic features of these tumors are reviewed. Grossly, seminal vesicle carcinoma is poorly circumscribed and solid or solid/cystic and may be misinterpreted as an abscess or hemorrhage on radiologic examination. Although a definitive diagnosis often cannot be given until after complete resection, we describe the findings indicative of seminal vesicle origin, including papillary histologic architecture, sometimes with mucinous differentiation, and a characteristic immunophenotype positive for CA-125 and cytokeratin 7, but negative for prostate-specific antigen and cytokeratin 20.     

Carcinoma of the seminal vesicle

Strict criteria were applied to 12 cases of carcinoma of the seminal vesicle in the Mayo Clinic tumor registry. Diagnosis was carcinoma of the seminal vesicle if the neoplasm was a papillary or anaplastic carcinoma localized primarily to the seminal vesicle and no other primary tumors were demonstrated. In addition, some degree of mucin production was required, especially when prostatic involvement was present. Only 2 of our cases and 35 cases reported previously were judged acceptable or probable cases of carcinoma of the seminal vesicle. Prognosis for patients with this tumor is poor. A combination of extirpative surgery and hormonal therapy appears to provide the best opportunity for extended survival, although this remains to be proved.     

Primary adenocarcinoma of seminal vesicle presenting as bladder tumor

A case of primary seminal vesicle carcinoma is described and is discussed in the context of current knowledge regarding the clinicopathologic features of this rare neoplasm.     

42例血精症病因的诊断与治疗

目的：探讨血精症病因的诊断与治疗。方法：对42例血精症患者中4l例进行超声引导下经会阴精囊穿刺造影，精囊液常规检查和细菌培养及其他检查；1例作直肠指检、CT与超声检查。针对血精症的病因采用多种方法进行治疗。结果：42例血精症的病因分别为前列腺癌、精囊癌和后尿道炎症各l例，精阜开口处息肉4例，精囊炎35例，其中17例并发前列腺炎。2例肿瘤源性血精症采用根治性前列腺和精囊切除术后治愈，35例炎性血精症采用超声引导下经会阴精囊穿刺滴注抗生素治疗后32例血精消失(91．4％)，4例精阜开口处息肉和l例后尿道炎症经相应治疗后痊愈。结论：血精症主要是下尿路生殖道的炎症，尤其是前列腺和精囊炎引起，超声引导下经会阴精囊穿刺和经导管滴注抗生素是一种诊断和治疗慢性精囊炎有效的方法。