无囊膜支撑的后房型人工晶体睫状沟缝线固定术

目的：探讨无囊膜支撑的后房型人工晶体睫状沟缝线固定术的有效方法。方法：术中使用改进的方法均成功完成后房型人工晶体睫状沟缝线固定术20例。结果：术后视力明显改善,最佳矫正视力≥0．5者13例（占65％）。结论：后房型人工晶体睫状沟缝线固定术是无囊膜时矫正无晶体眼性屈光不正,恢复双眼单视的最好方法。     

白内障超声乳化术中后囊膜破裂行后房型人工晶体睫状沟缝线固定术65例分析

目的观察白内障超声乳化术中后囊膜破裂后房型人工晶体睫状沟缝线固定术的手术方法和效果.方法65例白内障超声乳化术后囊膜破裂后行后房型人工晶体睫状沟线缝线固定术,随访6个月,对术后并发症进行分析.结果术后6个月视力≥0.5者占89%,无严重并发症发生.结论后房型人工晶体睫状沟缝线固定术是白内障超声乳化术中后囊膜破裂的一种补救措施.     

白内障超声乳化术中后囊膜破裂行后房型人工晶体睫状沟缝线固定术65例分析

目的 观察白内障超声乳化术中后囊膜破裂后房型人工晶体睫状沟缝线固定术的手术方法和效果。方法 65例白内障超声乳化术后囊膜破裂后行后房型人工晶体睫状沟线缝线固定术，随访6个月，对术后并发症进行分析。结果 术后6个月视力≥0．5者占89％，无严重并发症发生。结论 后房型人工晶体睫状沟缝线固定术是白内障超声乳化术中后囊膜破裂的一种补救措施。     

硅油取出联合Ⅱ期人工晶体植入缝线固定术42例临床分析

目的观察硅油取出联合Ⅱ期后房型人工晶体植入缝线固定术治疗无晶状体硅油填充眼的临床效果。方法对行硅油取出联合Ⅱ期后房型人工晶体植入缝线固定术的42例患者临床资料进行回顾性分析。结果绝大多数患者术后视力均较术前有不同程度的提高,全组病人术后矫正视力与术前矫正视力比较差异无统计学意义(P0.05)。结论硅油取出联合Ⅱ期后房型人工晶体植入缝线固定术是合理、安全、有效的手术方式。     

外伤性白内障后房型人工晶体缝线固定术

目的观察后房型人工晶体缝线固定术治疗外伤性白内障的临床疗效.方法对25例外伤性白内障因后囊破裂不能按常规法植入后房型人工晶体,而行后房型人工晶体睫状沟缝线固定术.结果术后23例人工晶体位置正常,2例人工晶体轻度倾斜;5例人工晶体前膜形成,经散瞳、球结膜下注射地塞米松后逐渐吸收,术后视力达0.2～0.6.结论后房型人工晶体睫状沟缝线固定术是治疗因后囊破裂的外伤性白内障的有效方法.     

外伤性白内障后房型人工晶体缝线固定术

目的 观察后房型人工晶体缝线固定术治疗外伤性白内障的临床疗效。方法 对25例外伤性白内障因后囊破裂不能按常规法植入后房型人工晶体，而行后房型人工晶状睫状沟缝线固定术。结果 术后23例人工晶体位置正常，2例人工晶体轻度倾斜；5例人工晶体前膜形成，经散瞳、球结膜下注射地塞米松后逐渐吸收，术后视力达0.2-0.6。结论 后房型人工晶状体睫状沟缝线固定术是治疗因后囊破裂的外伤性白内障的有效方法。     

虹膜固定型人工晶体与后房型人工晶体双襻缝线固定术治疗无后囊无晶体眼临床对比观察

目的评价虹膜固定型人工晶状体和后房型人工晶体双襻缝线固定术治疗无晶状体眼的疗效。方法无后囊膜无晶状体眼105例(110眼),55眼行虹膜固定型人工晶体植入术,55眼行后房型人工晶状体双襻缝线固定术。术后随访观察6个月,记录患者手术前后裸眼视力(VA)、最佳矫正视力(BCVA)、眼压(TOP)、手术时间、角膜内皮细胞计数及并发症情况。结果术后6个月时虹膜固定组BCVA为(0.50±0.26),32眼VA高于术前BCVA,23眼BCVA≥0.5,裸眼视力改善效果明显优于后房型人工晶体固定术组。结论虹膜固定型人工晶状体植入术治疗无晶状体眼,可安全、有效地提高患者术后视力。     

后房型人工晶体双襻缝线固定术

目的观察后房型人工晶体双襻缝线固定术的手术方法及疗效.方法 观察22例(23眼)手术结果随访1-12个月.结果术后视力≥0.5者72%.并发症主要为人工晶体偏心和倾斜.结论后房型人工晶体双襻缝线固定术,对于无后囊膜或后囊膜破裂者是一种可行有效的术式.     

人工晶体单襻睫状沟经角膜进针缝线固定治疗无晶体眼

目的:治疗后房型人工晶体巩膜缝线固定术治疗小切口非超声乳化白内障术中,后囊破裂无后囊膜支撑的无晶体眼。方法:人工晶体单襻睫状沟经角膜进针缝线固定。结果:术野清晰,操作简单,省时,无1例角膜内皮失代偿,视力0.3以上占90%。结论:小切口非超声乳化白内障摘除术,术中后囊破裂可选择人工晶体单襻睫状沟经角膜进针缝线固定术。     

前房型人工晶状体植入术与后房型人工晶体睫状沟缝线术治疗无晶体眼的比较

目的比较Artisan前房型人工晶体植入术及后房型人工晶体睫状沟缝线固定术治疗无晶体眼的疗效及并发症。方法 35例35眼无后囊膜支持的无晶体眼患者,随机分成两组,一组20眼行Artisan虹膜夹持型人工晶体植入术,另一组15眼选择后房型人工晶体睫状沟缝线固定术。观察手术前及手术后1天、1周、1个月的裸眼视力（VA）、最佳矫正视力（BCV）、眼压（IOP）、角膜内皮细胞计数（CECC）。结果两组术前、术后VA、BCV、CECC间比较,差异无统计学意义。Artisan组手术后BCV优于术前BCV,差异有统计学意义性。结论 Artisan前房型人工晶体植入术与后房型人工晶体睫状沟缝线固定术是治疗无晶体眼有效方法。Artisan前房型人工晶体植入术手术操作简单,组织损伤小,更加安全,是治疗无后囊膜支持的无晶体眼的比较理想的治疗方法。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.