气功调息的心率变异

应用心率变异分析（HRV）对18名气功师进行了调息前后的自主神经功能变化观察。HRV采用时域和频域两种方法。结果显示在调息状态下,交感神经活劝增强,LF、LF/HF明显增大、但RR^—无明显差异,提示气功调息对自主神经功能的调节主要表现为对瞬间心率的调控。     

调息对健康老人膈肌作用及肺功能的影响

调息，即以一定的方式调练呼吸。84位无心肺严重疾患的老年人．随机分组．采用双盲法，按随机发生数编号。在开始时，一年后，各测一次Pidmax（最大凝膈压）、VC、FEV_1.0、MMEF、MVV。结果显示：实验组调息前后自身对比、调息后与对照组相比，Pdimax、VC、FEV_1.0、MVV均有显著差异，P＜0．05，MMEF有极显著差异，P＜0．01。对照组的前后自身对比，各项皆呈下降趋势。表明：调息是一种能增强健康老人呼吸功能的有效锻练模式；Pdimax的显著改变，提示调息主要是通过锻炼膈肌。增强膈肌力量．从而提高呼吸功能。     

HRV结合神经递质分析对脑卒中患者预后价值探讨

[目的]探讨动态心电图心率变异性分析对急性脑血管卒中患者临床预后价值。[方法]分析108名脑卒中住院患者24h动态心电图各项指标及神经体液因素变化。[结果]脑卒中患者的HRV的参数值降低，即全部窦性R—R间期的标准差、每5min节段正常窦性R—R间期的标准差、高功率谱、低频功率谱、明显低于正常对照组患者，差异有显著性（P〈0．01）。脑卒中组神经递质变化显著高于正常对照组（P〈0．01）。[结论]HRV是脑卒中死亡的独立危险因素。同时脑卒中患者交感神经张力亢进。可能是导致心率变异性降低的主要原因。     

个体化运动处方对高血压合并2型糖尿病患者心率变异的影响

目的探讨高血压合并2型糖尿病（hypertensive patient complicated with type2 diabetes mellitus,EH＋T2DM）且有心率变异（heaa rate variability,HRV）异常的患者,接受常规降压、降糖药物治疗及个体化运动处方后HRV变化的情况。方法运动处方一为每日运动一次,15min／次;运动处方二为隔13运动一次,30min／次。运动量为靶心率≈{（60％-70％）×[（220—170）-实际年龄）]}次／分。30例符合研究对象患者随机分为三组,均接受常规药物治疗,其中A组接受运动处方一治疗,B组接受运动处方二治疗,C组不接受运动处方治疗。结果三组患者治疗三个月后HRV均有改善。治疗前后对比A、B组HRV改变有统计学意义（P〈0．05）,而C组HRV改变无统计学意义（P〉0．05）。A、B两组间HRV差异比较无统计学意义（P〉0．05）。结论常规降压、降糖药物对改善HRV作用不明显,个体化运动处方对改善HRV有较显著的作用。     

胆囊炎伴快心率依赖型Ⅰ度房室传导阻滞1例

患,男,6l岁,因右上腹阵发性疼痛月余人院。体检：急性病容,神志清晰,无心悸气短,既往无心肌炎。T：3TC,P：92次／min,心律不齐,心脏元杂音,BP：18．5／13．OKPa,Murphy征阳性。心电图示：Ⅰ导联心率为73次／min,P—R间期0．18S：Ⅱ、Ⅲ、avR、avL、avF、V1、V5导联心率为103次／min,P—R间期为0．2l～0．24S;avL、V3导联兼有上述二种改变,心电图诊断：窦性心律,间歇性快心率依赖型Ⅰ度房室传导阻     

B超观察妊娠早期胎心率变化的初步总结

目的初步总结妊娠早期胚胎心率在不同孕周的变化趋势,为临床提供参考信息。方法妇科常规超声检查,使用B超仪M取样,放大模式测量胎心率,确定临床医学参考值范围。结果妊娠早期胚胎心率相对中晚期妊娠总体较高,本组最高胎心率234次／min,最低胎心率96次／min;0～8周（151．93±20．86）次／min,0～9周（179．12±6．22）次／min,0～10周（175．06±6．66）次／min,0～12周（168．28±5．60）次／min;呈急升缓降趋势,并确定了早期胚胎心率临床医学参考值范围。结论妊娠早期胚胎心率的变化趋势与胎心解剖分化和传导系统的成熟高度相关,孕8周以前胚胎心率更易受外来因素影响。     

有机磷中毒病人出现低渗血症1例

患者女性30岁，主因：口服乐果1h。于1998年8月7日入院。患者自服乐果约20ml，20min后口吐白沫，大汗急送我院。查体：T36．5℃；P50次／min；R14次／min；Bp120／80mmHg。面色苍白，神志清晰、大汗。面部胸部可见肌颤。双侧瞳孔0．5mm，光反射不明显。双肺呼吸音粗，可闻及散在大中水泡音。心率50次／min，律齐。心音低。各瓣膜区均未     

不同频率下的停闭调息方式对心率变异的影响

目的研究停闭调息对自主神经功能的影响和阴阳调节机制.方法采用R-R间期的心率变异频谱分析方法,观察心率分别为16次/min和5次/min的吸-呼-停式和吸-停-呼式对心率变异性的影响.结果 16次/min的停闭调息的LF、HF、LF/HF均与调息前的自然呼吸无显著性差异.5次/min的吸-呼-停式可使LF、HF和LF/HF值明显升高(P<0.05);吸-停-呼式可使LF、LF/HF呈现出极显著性的升高(P<0.01),而HF值的变化不显著.结论①16次/min的吸-呼-停式和吸-停-呼式对自主神经功能的影响不明显.②5次/min的吸-呼-停式和吸-停-呼式均可导致交感神经的兴奋性升高.在此基础上,具有加强呼气作用吸-呼-停式可同时导致副交感神经系统的兴奋性升高;而具有加强吸气作用的吸-停-呼式,可使交感神经兴奋性呈现更为显著的升高.这两种停闭调息方式对内脏起到的阴阳调节作用各异.③不同的停闭调息后均可导致生理后效应.     

成功抢救复方苯乙哌啶中毒并发呼吸衰竭1例

患儿，男，3岁。入院前9h误服复方苯乙哌啶20～30片。5h前唤之不醒，3h前到当地医院查体：瞳孔散大，呼吸节律不整。经吸氧、吸痰、肌注洛贝林无好转而转我院。查体：T37．4℃，P104次／min，R0～1次／min，BP10／5．5kPa。深昏迷状态，全身皮肤发绀，双瞳孔7mm，对光反射消失。心率104次／min，律齐、心音尚有力。腹胀，肝脾未触及，膀胱区充     

红霉素静点引起过敏性休克一例

患者，女，74岁。有青霉素及粉尘过敏史。1993年7月20日晚，因气管炎收住院。查体：T37．8℃，P94次／min，R24次／min，BP20／12kPa，心率94次／min，节律齐，心音正常，两肺有少量干罗音，腹平软，肝、脾无触及。WBCll．3XIO’／L，N078，L0．22，住院后服自备氨茶碱0．ig，甘草片0．6s，配合穴位按摩，病入高枕卧位休息。因青霉素过敏采用红霉素0．sg，加入5％葡萄糖液500ml，静脉点滴，50滴／min。当液体进入体内约50ml时，病人诉头痛，胃难受，恶心，呼吸不畅而坐起。当时认为红霉素副作用，调慢滴速继续静点。10min后病人出现…     

Repeatability of heart rate variability during simple cardiovascular reflex tests on healthy subjects

BACKGROUND: Our purpose was to determine the repeatability, after 2 weeks, of frequency domain measures of heart rate variability (HRV) during simple cardiovascular reflex tests. METHODS: Twenty healthy volunteers aged 29.3 +/- 2.5 years were assessed twice (at weeks 0 and 2). Continuous electrocardiogram and minute-to-minute blood pressure were recorded during spontaneous and metronome-paced breathing (0.2 Hz). Under paced breathing, two tests were performed: 1) active change of posture: 5 min supine position, 5 min seated upright, and 5 min standing up, and 2) cold pressor test: the right hand was immersed in cold water (5 degrees C) for 2 min. RESULTS: Paced breathing elicited a significant increase of the high-frequency (HF) component of HRV. This effect was repeatable on 95% of the subjects. Active change of posture induced a significant increase of the heart rate with an increase of the low-frequency/high-frequency ratio of HRV. Although repeatability was better for the response to being seated upright than for the response to being standing up, it was always higher than 90%. The cold pressor test induced a significant increase of the heart rate and blood pressure, but with variable changes on the HRV measurements (either a decrease or an increase). Repeatability of responses was evident for 95-100% of the subjects. Although repeatability of HRV measurements in the same subject during the tests was higher than 95%, coefficients of repeatability reflected large differences among the subjects. CONCLUSIONS: The results suggest that it is not advisable to use isolated HRV changes to interpret the response to simple cardiovascular reflex tests in groups of healthy subjects.     

气功外气对秋水仙素酒精溶液紫外吸收光谱的影响

秋水仙素酒精溶液(3×10~(-5)mol/L)在气功外气作用约10min后,紫外吸收光谱波长为350nm的特征峰被移至330nm,吸光度约增大一倍.暗藏在距气功师约1.5m书包内的相同溶液,也出现了同样变化.非气功人员数人模拟发功动作后,与对照组之间无任何差异.提示气功外气改变了该溶液的分子结构.     

A preliminary study on the changes of T-cell subsets in patients with aplastic anemia treated with qigong

It has been well known that Qigong keeping one in a self-controlling condition is a traditional method for promoting human health, prolong life and treating several kinds of diseases refractory to other remedies. As aplastic anemia (AA) is one of the disease poor responded to conventional therapy. Qigong was applied to a number of AA patients. Five principle methods of Qigong were practiced as fellows: (1) Regulating respiration consciously to tonify Qi; (2) ameliorating the digestive function on tiptoe; (3) holding one's head for tranquilizing; (4) massaging the loins to nourish the essence; (5) at one's ease to regulate the circulation of Qi and blood. Besides according to the various conditions of different patients, some other Qigong methods such as for anti-inflammation and analgesia, diuretic, massage to viscerals etc. were also applied for symptomatic treatment. In authors' previous work by ABC immune enzymic assay, the authors have shown in most AA patients, their suppressor T cell (Ts) were significantly increased, the helper T cell (Th) dropped resulting in a decreased ratio of Th/Ts. The changes of T-cells subsets were investigated in 10 cases treated by Qigong. For the patients in Qigong therapy, their Th and the ratio of Th/Ts were greatly elevated than those without Qigong treatment (P less than 0.02). In addition, Ts went down but not significantly in Qigong treating patients. Because the change of T cell subsets play an important role in the pathogenesis of AA, the reversion of the change by treating with Qigong may be a promising way for recovery of the AA patients.     

Effects of Qigong Exercises on 3 Different Parameters of Human Saliva

Objective： To analyze the effects of a Qigong program on various parameters of unstimulated saliva, including volume, pH and secretory immunoglobulin A （S-IgA） level. Methods： Twice a day from the beginning of Fall 2005, twenty-three healthy volunteers aged 22-24 did special Qigong exercises and massage of acupuncture points which stimulated the energy cycle and increased body water energy. The unstimulated saliva volume and pH were recorded every week in Spring （April, May, June） 2005 before the volunteers started to learn and exercise Qigong, and after Qigong intervention in Spring （April, May, June） 2006. During the period of study, saliva was collected in the same location and on similar dates at the Dental Faculty of Tehran University of Medical Sciences. The S-IgA levels of the last samples of the last week of Spring 2005 and 2006 were measured. Results： The unstimulated saliva volume after Qigong exercises （2.94±0.20 mL/5min） was significantly higher as compared to the pre-Qigong phase （1.65±0.102 mL/5min, P〈0.05）. The S-IgA level was 105.45±69.41 mg/mL before doing Qigong exercises, and 156.23±88.56 mg/mL after doing Qigong exercises, and a statistically significant difference was seen between the two measurements （P=0.005）. The change in pH was not statistically significant. Conclusions： The application of Qigong is beneficial for increasing salivary volume and other parameters. Moreover, the results suggest that Qigong may be a useful medication for patients with salivary hyposecretion. Further research is recommended in examining the long-term effects of Qigong on improving salivary volume and other parameters in individuals with salivary hyposecretion.     

针刺刺激可达到前气功状态

目的：研究在短时间之内使普通人进入前气功状态的方法。方法：健康的试验参与者以不随机的方式纳入本次研究。使用多通道生理记录仪检测试验参与者是否有进入前气功状态。参与者在针刺合谷穴的时候获得酸（得气）的感觉,同时暗示参与者丹田处有热及放松的感觉,由此让参与者进入一个松、静、自然的前气功状态。结果：本研究中,72.2%没有习练气功经历的参与者成功进入前气功状态。参与者进入气功状态后,大部分生理指标与基线指标相比有显著差异。结论：使用针刺引起酸的感觉可以让试验参与者快速进入前气功状态。因此气功的研究不再限制在特定的人才可以实行,本研究方法可以应用到每个人身上。     

气功锻炼预防血栓形成的临床观察

用RIA法测定GMP－140、TXA2、PGI2，用酶法测定CH、TG、HDL，用萤光偏振法测定红细胞膜流动性。观察232例，其中健康中老年47例，高脂血症患者185例；气功组152例，对照组80例。气功锻炼3个月前后血浆中的变化、结果表明气功锻炼后，GMP－140含量较功前明显减少；TXB2含量明显减少，6－K－PGF1α量无明显变化，T／K比值明显减小；红细胞膜流动性明显增强；TG和CH均显著减少，HDL有明显增多，经统计处理均有显著性差异（P＜0．01～0．001）。而对照组无明显变化。提示气功锻炼通过提高红细胞膜的流动性，抑制血小板激活，调节血管内皮细胞功能，加强体内脂质代谢，共同起到预防血栓形成的作用。     

气功防治高血压远期疗效的对比观察：306例患者25—30年随访

306例高血压病人随机分为气功组(气功加规律服用小剂量降压药)154例和对照组(仅规律服用小剂量降压药)152例。25～30年随访发现:气功组血压稳定率为86.56%,对照组血压稳定率为68.87%,气功组疗效较佳。25～30年随访期间气功组总病死率(22.73%)明显低于对照组(40.79%)。进一步分析发现气功组脑卒中发生率为18.83%,病死率为14.29%,而对照组则分别达33.55%和28.95%,气功组明显低于对照组(P<0.01),14项脑卒中危险和防护因子的多因子回归分析,提示脑卒中的发生与坚持气功锻炼呈负相关。以上结果表明气功锻炼具有预防脑卒中和改善高血压预后的有益作用。     

腹式呼吸对心算任务后心率变异的影响

目的观察正常人群在心算任务下心率变异性的变化及腹式呼吸对心率变异的调节作用。方法选择正常健康被试者21名采用短程测量法分别采集静息期、心算刺激下及腹式呼吸中心率变异的频域指标,并进行前后对照。结果被试者心算刺激下与静息时的心率变异频域指标比较LF(z=-1.93,P<0.01)、LF/HF(t=2.38,P<0.05)、LF%(t=3.43,P<0.01)均上升,HF%则明显下降(t=3.25,P<0.01)。被试者腹式呼吸与心算刺激的比较中,心率变异频域指标LF/HF(z=-2.24,P<0.05)、LF%(t=3.47,P<0.01)、LFPK(t=2.37,P<0.05)显著增高,HF%显著降低(t=-2.23,P<0.05)。结论正常人群在心理应激中表现出交感神经的活动增强,副交感神经抑制,腹式呼吸能调节自主神经低频峰值趋于向理想的峰值靠近。     

Influence of qigong therapy upon serum HDL-C in hypertensive patients

The serum HDL-C concentration of 100 hypertensive patients had been measured. The results showed that the mean levels of cholesterol (Tc), triglyceride (Tg), LDL-C and AI (AI-Tc-HDL-C/HDL-C) in the serum of male hypertensive patients (n = 100) all were significantly higher than those of male normotensive subjects (n = 50), while the mean levels of serum HDL-C, HDL-C/Tc and HDL-C/LDL-C of male hypertensive patients all were significantly lower than those of male normotensive subjects. The 100 hypertensive patients were also divided randomly into Qigong group (Qigong with regularly antihypertensive drug taking, n = 50) and control group (with regularly antihypertensive drug taking only, n = 50). After one year treatment, in Qigong group, the levels of Tc, Tg, LDL-C and AI were decreased; while the levels of HDL-C, HDL-C/Tc and HDL-C/LDL-C were significant increased. In control group, however, no significant changes were found. The differences between the two groups both were statistically significant (P less than 0.05-0.001). The above results indicated that Qigong practising could elevate serum levels of HDL-C and regulatory metabolism of lipid.