患神经症士兵的心理健康状况及人格特征研究

目的探讨患神经症士兵的心理健康状况与人格特征之间的关系。方法采用心理卫生症状自评量表（Symptom Checklist90,SCL-90）、艾森克人格问卷（Eysenck Personality Questionnaire,EPQ）对32名住院患神经症士兵进行了调查。结果患神经症士兵各因子分均高于男军人常模（P〈0.05）,且主要集中在强迫、焦虑、抑郁因子上。患神经症士兵的EPQ中精神质（P）和神经质（N）维度分高于中国男军人常模（P〈0.05）,内外向性（E）维度分低于中国男军人常模（P〈0.05）,掩饰程度（L）维度无显著差异。患神经症士兵EPQ的N分与SCL-90总均分和各因子分呈正相关,P分与SCL-90总均分和人际敏感、抑郁、焦虑、偏执、精神病性呈正相关,E分与人际敏感、抑郁呈负相关,除躯体化、恐怖以外,EPQ的L分与SCL-90总均分及各因子分呈负相关。结论患神经症士兵存在着较多的心理问题,新兵入伍前进行SCL-90、EPQ检查,可有效的减少有严重心理卫生问题或精神病患者带病入伍。     

军事应激条件下军人个性特征和应对方式及心理健康的关系研究

目的：探讨军事应激条件下军人个性特征、应对方式及心理健康的关系．方法：采用症状自评量表(SCL-90)、EPQ和应对方式量表,对参加军事演习的某部队985名军人进行现场问卷调查．结果：①应激军人SCL-90得分,除抑郁外,各因子分显著地高于军人常模．EPQ的4个纬度,除L外,P、E、N显著地高于军人常模．而积极应对和消极应对显著低于国内常模．②积极应对与其SCL-90的总均分呈现明显负相关,而消极应对则与之呈明显正相关;P、E、N与消极应对方式呈显著正相关,P、L与积极应对方式呈显著负相关．③从对军事应激条件下军人心理健康状况作用大小来看,消极应对方式的作用最大,依次为P、N、L、积极应对．④N和消极应对对军事应激条件下军人心理健康的直接效应是显著的．结论：军事应激条件下军人的心理健康受个性特征与应对方式的影响。     

医务人员个性特征与心理健康相关性研究

目的 研究医务人员个性特征与心理健康的关系,为有针对性的对医务人员开展心理健康教育和有关部门在制定相关政策时提供依据和参考.方法 用症状自评量表(SCL-90)和艾森克个性问卷(EPQ成人型)对东莞市厚街镇644名医务人员进行心理健康状况调查.结果 医务人员SCL-90各因子中躯体化、人际关系、恐怖、偏执、精神病性因子与中国常模相比差异有统计学意义;EPQ评分P、E、N及L分与中国常模相比差异均有统计学意义;EPQ量表的N分和P分与SCL-90各因子分存在正相关关系;有明显心理健康问题者的N分和P分均较高:不同个性类型明显心理健康问题的检出率间的差异有统计学意义,检出率从高到低顺次的个性类型为内向不稳定型、外向不稳定型、外向稳定型和内向稳定型.结论 医护人员心理卫生水平总体较好,其个性特征与心理健康状况关系密切,具有神经质倾向、精神质倾向、性格内向的个性特征者容易出现不良心理体验,应重视和关注医务人员的心理健康问题.     

高三教师心理健康水平与人格特征的相关研究

目的 研究高三教师的心理健康、人格特征状况及两者关系.方法 应用症状自评量表(SCL-90)、艾森克人格问卷(EPQ)测评337名高三教师.结果 教师的SCL-90在躯体化[(1.54±0.58)分]、抑郁[(1.57±0.51)分]、精神病性[(1.35±0.43)分]和阳性项目数[(44.11±25.68)分]显著高于全国常模(P＜0.05,P＜0.01),人际关系敏感显著低于常模;教师EPQ中N量表与SCL-90总分及所有因子分显著正相关,P量表与SCL-90总分及7个因子分显著正相关;回归分析表明,神经质N、精神质P和掩饰度L对心理健康有预测作用.结论 应对高三教师加强健全人格教育,提高其心理健康水平.     

急诊科护士心理健康状况与人格特征的相关分析

目的 探讨急诊科护士的心理健康状况与人格的关系,为医院的管理提供有价值的数据.方法 68名急诊科护士进行SCL-90和EPQ测查,同时分析心理健康状况与人格之间的相关性.结果 急诊科护士在SCL-90躯体化(1.58±0.51)、焦虑(1.658±0.47)、恐怖(1.48±0.39)等因子得分高于常模,差异具统计学意义(P＜0.05);SCL-90各因子分子与EPQ的N分呈显著正相关,躯体化和敌对因子与P分呈显著正相关,人际关系和抑郁因子与E分呈显著负相关.结论 情绪稳定性对急诊科护士的心理健康影响最大,医院的管理者可以参考EPQ测定结果选拔合适的人选进入急诊科,同时要加强心理卫生指导,促进心理健康.     

粉尘作业工人心理卫生状况调查

目的探讨粉尘作业工人心理卫生状况。方法148名粉尘作业工人统一填症状自评量表(SCL-90)和艾森克人格问卷(EPQ)。并将其SCL-90各症状因子分与724名国内常模组进行对比和统计处理。根据SCL-90各症状因子分筛查阳性,划分成心理问题组和心理健康组,将两组EPQ各量表分进行对比和统计学处理。结果粉尘作业组筛查阳性42例,占28．38％,与国内常模组各症状因子分比较躯体化、焦虑敌对、恐怖因子分差异显著(P＜0．05)。心理问题组与心理健康组EPQ各量表分比较,神经质型量表分差异非常显著(P＜0．01)。结论28．38％的粉尘作业工人有不同程度的心理问题,其个性特征为神经质型。     

高一年级学生自我概念与心理健康的相关性研究

目的　探讨灵武市高一学生自我概念与心理健康的关系。方法　采用症状自评量表 (scl- 90 )和自我概念量表Piers-Harris,对 172名高一学生进行统一测评。结果　自我概念的行为与焦虑因子分显著低于常模(P <0 .0 5或 P <0 .0 1) ,而躯体外貌与属性因子分显著高于常模 (P <0 .0 1) ;低自我概念组的学生 ,心理问题相对较多 ;自我概念总分、各因子分与scl- 90总分、各因子分均呈负相关。结论　自我概念得分较高者 ,心理问题相对较少。     

高三教师心理健康水平与人格特征的相关研究

目的研究高三教师的心理健康、人格特征状况及两者关系。方法应用症状自评量表(SCL-90)、艾森克人格问卷(EPQ)测评337名高三教师。结果教师的SCL-90在躯体化[(1．54±0．58)分]、抑郁[(1．57±0．51)分]、精神病性[(1．35±0．43)分]和阳性项目数[(44．11±25．68)分]显著高于全国常模(P＜0．05,P＜0．01),人际关系敏感显著低于常模；教师EPQ中N量表与SCL-90总分及所有因子分显著正相关,P量表与SCL-90总分及7个因子分显著正相关；回归分析表明,神经质N、精神质P和掩饰度L对心理健康有预测作用。结论应对高三教师加强健全人格教育,提高其心理健康水平。     

高原山区军人的人格特征和心理健康状况研究

目的研究高原山区环境对军人的心理健康状况的影响,为军队心理保健提供依据。方法采用心理健康测查表（PHI）、艾森克个性问卷（EPQ）对某高原山区军人进行心理状况调查。结果高原山区军人在PHI中除UNR外,各临床量表均高于常模组（P〈0．05～0．01）;EPQ与全国常模比较,E分增高（P〈0．01）,L分降低（P〈0．05）,与普通军人常模比较E和N分均增高（P〈0．05—0．01）;PHI与EPQ相关分析表明,EPQ的P分和N分与PHI各临床因子分呈正相关（P〈0．05—0．01）,E分与HMA呈正相关（P〈0．001）,而E分与DEP、SOM和ANX呈负相关（P〈0．01,0．05）,L与PHI各临床因子分呈负相关。结论高原山区军人存在较多的心理问题,心理问题的发生可能与长期艰苦的生活环境、军队性质、个性特征等多种因素有关。     

卫校高护生心理健康状况与个性特征的调查分析

目的 探讨卫校高护生个性特征对其心理健康的影响.方法 采取整群抽样,对某卫校172名高护生进行症状自评量表(SCL-90)和艾森克个性问卷(EPQ)调查.结果 (1)卫校高护生有33.7%存在心理健康问题,其中1.7%存在中度以上的心理健康问题;(2)高护生9个因子分与常模相比差异有显着性意义(P＜0.01);(3)高护生P、E、N分与常模差异不显着(P＞0.05),L分较常模低且有显着性意义(P＜0.001);(4)SCL-90的9因子与N维度呈显着正相关(P＜0.001),除敌对外其余因子均与E维度呈负相关(P＜0.05),敌对、抑郁和偏执3因子与P维度呈正相关(P＜0.05),敌对与L维度存在显着性负相关(P＜0.001).结论 卫校高护生的心理健康水平较低,个性特征及成长环境在心理健康问题方面起着重要作用.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.