长脉冲翠绿宝石激光治疗141例多毛症的疗效观察

依据选择性光热作用原理，各种激光广泛应用于多余毛发的脱除治疗，我院于2002年应用美国生产的激光治疗仪治疗141例多毛患者，取得良好疗效。     

多毛症及其激光治疗的研究进展

多毛症是临床上的一种常见病，累及8％～15％的女性。虽然对患者的身体健康不产生严重后果，但对患者的美观和心理会产生较大影响，日益受到广泛关注。该病的治疗方法较多，疗效各异。近年在国外取得较大进展的激光脱毛法，效率高，疼痛轻，并发症少，是目前临床上治疗多毛症的一个有前景的课题。本文对激光治疗多毛症的研究进展作了综述。     

应用CSM-8电针美容仪治疗毛细血管扩张症的疗效观察

毛细血管扩张症是指近皮肤或黏膜表面的细静脉、毛细血管和细动脉呈持久的细丝状、星状或网状扩张,损害呈鲜红色,压之不褪.可长期无变化或扩大,患者因影响美容而非常痛苦.病因多由使用过量糖皮质激素或冻伤、酒渣鼻等致,也可由SLE、着色干皮病、皮肤异色症等引发,来我科治疗的毛细血管扩张症患者多数是美容问题.我们随机把患者分成2组,分别用CSM-8电针美容仪和GX-Ⅱ型多功能电离子治疗,结果如下.     

药物治疗女性多毛症的研究进展

药物治疗女性多毛症的研究进展王学民，陈霞凤综述李长恒审校上海市皮肤病防治所皮肤病防治科（邮政编码２０００５０）女性多毛症（ＨｙｐｅｒｔｒｉｃｈｏｓｉｓＦｅｍａｌｅ，ＨＦ）一般可分为三型，即自发性多毛症（ＩｄｉｏｐａｔｈｉｃＨｉｒｓｕｔｉｓｍ，ＩＨ）、...     

国产光子脱毛仪治疗多毛症疗效观察

目的观察国产光子脱毛仪治疗多毛症的临床疗效。方法采用国产的光子脱毛系统对148例患者各部位多余毛发治疗，反复2～7次，每次间隔4～6周。疗程结束随访6个月。治疗前后进行对比，记录效果并让病人对满意度打分。结果所有患者均能耐受治疗。脱毛总有效率为91．9％。病人满意度为83．1％，副反应发生率为4．1％。结论国产光子脱毛仪疗效满意，操作简单，治疗费用明显低于进口机，对多毛症患者是一个很好的选择。     

半导体激光辅助药物治疗带状疱疹60例疗效观察

我科近年来采用阿昔洛韦加半导体激光局部照射治疗带状疱疹神经痛，取得了显著效果，报道如下。     

1450nm半导体激光治疗痤疮临床疗效观察

目的观察1450nm半导体激光治疗痤疮的疗效及安全性。方法应用1450nm半导体激光对72例痤疮患者进行治疗。治疗前在局部外涂复方利多卡因乳膏,15～20min后进行治疗,激光光斑直径为6mm,能量密度为9～12J/cm2,动态冷却(DCD)时间为22～26ms;每次间隔为2～3周。结果治疗3次后,总皮损和炎症性痤疮皮损分别减少52.8%与79.4%,随访6月后皮损继续减少,与治疗前相比,差异有统计学意义。术后局部可出现红斑和炎症后色素沉着,但无水疱形成和色素减退。结论1450nm半导体激光治疗炎症性痤疮安全而有效。     

1450 nm半导体激光治疗痤疮临床疗效观察

目的：探讨1450nm半导体激光对痤疮的疗效及安全性。方法：应用1450nm半导体激光对44例中、重度痤疮患者进行一侧面部治疗,激光光斑为6mm,剂量为8—12J／cm^2,动态冷却（DCD）时间为20—30ms。结果：治疗3、4次后,痤疮皮损分别减少67．3％与88．1％,与对照侧相比,差异有统计学意义。术后局部无色素沉着。结论：1450nm半导体激光治疗痤疮安全而有效。     

脉冲染料激光治疗蜘蛛痣206例疗效观察

应用脉冲染料激光治疗206例蜘蛛痣患者，结果206例患者中201例痊愈，痊愈率为97.6%，其中102例患者经过1次激光治疗即痊愈，79例患者经过2次治疗痊愈，20例患者经过3次治疗痊愈。无1例有肥厚性或萎缩性瘢痕，随访1例均无复发。     

CO2激光治疗20种皮肤病疗效观察

目的：评价CO2激光治疗多种皮肤病的疗效及其在皮肤科治疗上的应用。方法：利用CO2激光的热作用对病变组织进行凝固、汽化和／或切割治疗，而使病变组织破坏而清除。结果：共治疗皮肤性病科20个病种1516例患者，治疗次数1～2次，痊愈1459例(96.24％)，显效54例(3．56％)，有效3例(0．20％)，无效0例(0．00%)。结论：CO2激光对皮肤科多种疾病有较好疗效。     

Pili bigemini complicating diode laser hair removal

After two diode laser treatments for hair removal, a 39-year-old woman was noted to have pili bigemini within the treated areas. It resolved after a third treatment. Pili bigemini, the appearance of two hairs coming from the same follicular opening, can be induced by intermediate doses of laser energy. It follows sublethal damage to the hair follicule apparatus.     

长脉冲半导体激光脱毛的长期疗效和安全性评价

目的 评价长脉冲半导体激光对于Ⅲ－Ⅴ型皮肤多毛患者脱毛的长期疗效和安全性。方法 用长脉宽半导体激光（波长800 nm，脉宽30 ms，光斑大小9 mm × 9 mm）对350例多毛患者进行多次治疗。治疗结束后22.5个月，回顾性分析了脱毛的疗效和不良反应，每个部位根据治疗次数分2组： < 6次组和≥6次组（腋窝分为 ＜ 4次组和≥4次组），比较不同部位这2组脱毛的疗效。结果 随访到并进行评价的多毛患者235例共375处部位。经2 ~ 18次脱毛治疗后，有效302处，总有效率为80.53%。不同部位2个治疗次数组疗效有一定差异，唇部≥6次组治疗部位38处，有效33处，有效率86.84%， ＜ 6次组治疗部位20处，有效7处，有效率35.00%；面颈（唇以外）≥6次组治疗部位38处，有效26处，有效率68.42%， ＜ 6次组治疗部位13处，有效4处，有效率30.77%；下肢≥6次组治疗部位50处，有效46处，有效率92.00%， ＜ 6次组治疗部位9处，有效5处；躯干≥6次组治疗部位23处，有效20处，有效率86.96%， ＜ 6次组治疗部位8处，有效4处；以上各部位≥6次组疗效均优于 ＜ 6次组（P < 0.05）。腋窝≥4次组治疗部位97处，有效91处，有效率93.81%， ＜ 4次组治疗部位9处，有效5处，两组疗效比较，P < 0.01。上肢部两组疗效比较，差异无统计学意义（P ＞ 0.05）。235例患者中有6例出现不良反应，包括色素沉着、毛囊性丘疹、瘙痒、水疱、白色毛发，未见色素减退及瘢痕形成。结论 长脉冲半导体激光对Ⅲ－Ⅴ型皮肤多毛患者脱毛安全有效。疗效与脱毛部位、治疗次数相关。     

Effects of the 755-nm Alexandrite laser on fine dark facial hair: review of 90 cases

Laser hair removal is a relatively effective method for thick hair. Despite the risk for induction of fine hair growth, application of laser for fine dark hair is sometimes inevitable. We investigate the effects of 755-nm Alexandrite laser on fine dark facial hair and evaluate the induction rates of fine hair growth and case satisfaction. In the present study, the thickening rate of hairs (33.33%) was found to be higher than the previously published rates. However, reduction of hair density can be obtained when the laser sessions are continued.     

Paradoxical effects of hair removal systems: a review

Although a variety of lasers have proven to be clinically effective for long-term hair removal, the use of these lasers has also been associated with undesirable side effects, such as hyper- and hypopigmentation, crusting, erythema, and edema. One notable side effect that seems to be underreported in the literature is the growth of fine dark hair in untreated areas close to the treated ones. This contradictory hypertrichosis is known as the paradoxical effect. In this paper, we review the published reports of the paradoxical effect and offer some possible explanations for this effect. The paradoxical effect has been documented most commonly after the use of induced pulse light and alexandrite lasers. One possible explanation is the activation of dormant hair follicles by suboptimal fluences. Another mechanism may be the synchronization of hair growth cycles by direct light stimulation.     

Patient satisfaction with laser hair removal

Background Laser hair removal (LHR) is a widely used treatment for unwanted hair. Aim To determine patient satisfaction with LHR. Methods The clinic offered LHR by long pulse ruby, alexandrite and Nd:YAG. Patients attending the LHR clinic completed a patient satisfaction questionnaire. Satisfaction with LHR treatment was recorded on a linear analogue scale (LAS 0 = laser very much worse than alternative method; 10 = laser very much better than the alternative method). Results In terms of hair removal, 71% of patients were satisfied with their treatment. Laser treatment compared favourably with electrolysis and waxing. LHR scored 8.6 when compared with electrolysis and 7.7 when compared with waxing. During LHR treatments, 61% of patients used fewer ancillary methods than before. Most patients would recommend LHR to other persons with unwanted hair. Conclusions Most patients were satisfied with LHR.     

Alexandrite laser hair removal results in 2359 patients: A Turkish experience

Background: Various lasers have been developed for epilation of unwanted hair. Effective hair removal in the Turkish population can be difficult, and multiple treatments are usually required for effective treatment. Objective: To evaluate the safety and efficacy profile of a long-pulsed alexandrite laser for hair removal in the Turkish population with Fitzpatrick skin types II–V exclusively and to determine the benefit of multiple treatments. Methods: Retrospective clinical evaluation conducted from September 2005 to May 2008 at a referral private clinic. Pre-laser skin testing was performed starting at 16 J/cm² and the energy fluence was selected according to response. All subjects were followed for 6 months after their final treatment. Results: A total of 2359 patients are reported (264 men and 2095 women) ranging in age from 14 to 70 years, for a total of 3830 treatment sites. The majority of treatment sites were axillae (24.2%) followed by the bikini line (16.8%). Maximum reductions observed were 95% for axillae, 92% for the bikini line, 86% for breast, respectively. The patients had a mean 80.6% hair reduction. Complications occurred in only 2.2% of cases. Transient hyperpigmentation (0.7%), folliculitis (0.5%), transient hypopigmentation (0.5%), and blistering (0.4%) were commonly seen complications. No subjects had scarring or long-term pigmentary changes. Conclusion: The long-pulsed alexandrite laser is safe for hair removal in darker skin tones. Although Turkish skin can be effectively treated with a cooled, long-pulsed alexandrite laser, complications do occur.     

Effect of hair removal by Nd:YAG laser on the recurrence of pilonidal sinus

Background  Pilonidal sinus (PNS) is chronic inflammatory process of the skin in the natal cleft. Management of PNS is mainly surgical. Although different types of surgery have been performed, the recurrence rate is still high.
Objective  To evaluate the effectiveness of laser hair removal (LHR) in the natal cleft area on the recurrence rate of PNS as an adjuvant therapy after surgical treatment.
Methods  Twenty five patients with PNS were included in this study. Fifteen patients underwent LHR treatment using Nd:YAG laser after surgical excision of PNS (Patients group) while ten subjects with PNS did not do LHR and served as a control group.
Results  All of the patients were male patients. Their age ranged from 17 to 29 years with a mean of 21.60 ± 3.13 years. They had Fitzpatrick skin type III, IV and V. The patients have got 3 to 8 sessions of LHR (mean 4.87 ± 1.64). Follow up period lasted between 12 to 23 months. None of the patients, who underwent LHR, has required further surgical treatment to date. Seven patients out of ten in the control group have developed recurrent PNS. Pain was the most frequent side effect and it was seen in 6 patients (40%).
Conclusion  LHR can prevent the recurrence of PNS. LHR should be advised as an essential adjuvant treatment after surgical excision of PNS. In non-complicated recurrent PNS, LHR is strongly advocated to be started before and continued after doing surgical treatment.     

An efficacy comparison of hair removal utilizing a diode laser and an Nd:YAG laser system in Chinese women

Abstract

Background: The 800 nm diode laser and the 1064 nm Nd:YAG laser have been used successfully for hair removal for many years. Objective: To compare the efficacy of a diode laser with a Nd:YAG laser regarding axillary fossa hair removal in Chinese women. Methods: Twenty-nine Chinese women underwent three treatment sessions at 4-week intervals with a diode laser (34–38 J/cm²) on one side and a Nd:YAG laser (34–40 J/cm²) on the other side. Assessments included the reduction of hair diameter following treatment, the regrowth rate in hair length, total hair reduction and the immediate pain associated with the treatments. Results: At follow-up visit number 1 (4 weeks after the first session), the average reduction in hair diameter on the diode laser side and the Nd:YAG laser side was 2.44 μm and –0.6 μm, respectively. The regrowth rates of the hair were 61.93 μm/day and 59.84 μm/day, respectively, which were not statistically significant (p > 0.05). At follow-up visit number 1, hair reduction was 60.09% and 41.44%, respectively. At follow-up visit number 2 (4 weeks after the second session), hair reduction was noted to be 78.56% and 64.50%, respectively, which were both statistically significant (p < 0.05). Immediate pain scores at the first session were 6.97 and 6.17, respectively; at the second session were 5.48 and 6.69, respectively; and at the third session were 5.76 and 7.45, respectively; all statistically significant (p < 0.05). Conclusions: The diode laser showed more efficacy and was found to be more comfortable than the Nd:YAG laser for axillary fossa hair removal in Chinese women.     

808 nm半导体激光脱毛的疗效分析

目的：评价808 nm半导体激光低能量多脉冲方式脱毛的疗效。方法：采用半导体激光脱毛仪对362例患者421个部位进行脱毛治疗（波长808 nm,脉宽100 ms,光斑直径10 mm×12 mm,能量密度11～15 J/cm2,频率5 HZ）,共5次。结果：腋部、下肢、上肢的1～5次治疗平均脱毛率分别达20%、30%、60%、70%和80%以上,唇部1～5次治疗平均脱毛率分别为15%,22%,31%,42%,51%。未见明显不良反应。结论：808 nm半导体激光脱毛安全有效。