共查询到20条相似文献，搜索用时 15 毫秒
1.
Kathrin J. Grochau Ali-Farid Safi Uta Drebber Andrea Grandoch Joachim E. Zöller Matthias Kreppel 《Journal of cranio-maxillo-facial surgery》2019,47(3):505-509
Purpose
The aim of this prospective work was to examine oral leukoplakia for their podoplanin expression to determine whether podoplanin expression is associated with the degree of dysplasia.Materials and methods
We took biopsy samples from 50 patients with oral leukoplakia in 2013. The preparations studied by immunohistochemistry were analyzed in correlation with the degree of dysplasia and other clinicopathological variables.Results
The Chi-square test showed a significant correlation between podoplanin expression and the degree of dysplasia according to the squamous intraepithelial neoplasia (SIN) classification (p = 0.033). Also, a significant association between age grouping and podoplanin expression was found. We were able to show that the distribution is the same for both age groups in relation to the score of podoplanin expression (p = 0.003).Conclusion
In a comparable retrospective work of our working group, it could be shown that podoplanin is a reliable predictive marker for the assessment of the risk of malignant transformation. The present work was able to substantiate the assumption that podoplanin not only plays an important role in the context of malignant degeneration but also exerts a major influence in advance. 相似文献2.
Cristiane Barbosa Lopes Luciana Armada Fábio Ramôa Pires 《Journal of endodontics》2018,44(7):1105-1109
Introduction
The aim of the present study was to compare the immunoexpression of CD34, intercellular adhesion molecule-1 (ICAM-1), and podoplanin and the presence of mast cells with clinical, demographic, radiologic, and histologic features from periapical granulomas, periapical cysts, and residual cysts.Methods
Thirty-one lesions (5 granulomas, 15 periapical cysts, and 11 residual cysts) were selected. Histologic sections in silanized slides were used for the immunohistochemical reactions. The analysis of the images was performed by using an optical microscope, and data were analyzed with 5% significance (P < .05).Results
Cysts presented atrophic and hyperplastic epithelium in 11 cases (35.5%) and 15 cases (48.8%), respectively (P > .05). The intensity of the inflammatory infiltrate was similar when comparing the 3 groups (P > .05). CD34 and podoplanin expression and the presence of mast cells were similar when comparing the 3 groups; ICAM-1 expression was more intense in granulomas than cysts (P < .05). There were no statistically significant differences associated with the expression of the evaluated markers according to the intensity of the inflammatory infiltrate.Conclusions
There were no differences in the expression of CD34 and podoplanin and in the presence of mast cells when the 3 groups were compared. ICAM-1 expression was more common in periapical granulomas. 相似文献3.
Statement of problem
Lack of an accepted definition for the ascending ramus of the mandible means no common reference point is available for clinical or research dialogue.Purpose
The purpose of this review was to determine whether the ascending ramus has been defined, by using a search of published studies.Material and methods
PubMed was searched, using terms “ascending ramus” and “mandible.”Results
The search found no acceptable definition of the ascending ramus of the mandible.Conclusions
An acceptable definition for the ascending ramus of the mandible is lacking, and one is proposed here. 相似文献4.
Domenico Ricucci Simona Loghin Lucio S. Gonçalves Isabela N. Rôças José F. Siqueira 《Journal of endodontics》2018,44(3):405-413
Introduction
This histobacteriologic study described the pattern of intraradicular and extraradicular infections in teeth with sinus tracts and chronic apical abscesses.Methods
The material comprised biopsy specimens from 24 (8 untreated and 16 treated) roots of teeth associated with apical periodontitis and a sinus tract. Specimens were obtained by periradicular surgery or extraction and were processed for histobacteriologic and histopathologic methods.Results
Bacteria were found in the apical root canal system of all specimens, in the main root canal (22 teeth) and within ramifications (17 teeth). Four cases showed no extraradicular infection. Extraradicular bacteria occurred as a biofilm attached to the outer root surface in 17 teeth (5 untreated and 12 treated teeth), as actinomycotic colonies in 2 lesions, and as planktonic cells in 2 lesions. Extraradicular calculus formation (mineralized biofilm) was evident in 10 teeth.Conclusions
Teeth with chronic apical abscesses and sinus tracts showed a very complex infectious pattern in the apical root canal system and periapical lesion, with a predominance of biofilms. 相似文献5.
6.
Leila Galiay François Simon Raphaël Lévy Vincent Couloigner Jean Donadieu Julie Toubiana Thomas Blauwblomme Roman Hossein Khonsari 《Journal of cranio-maxillo-facial surgery》2018,46(8):1179-1184
Purpose
Gorham-Stout disease (GS) is a rare and little understood bone disease that leads to the progressive replacement of the affected bone by fibrous tissues. The mandible is the most commonly affected craniofacial bone, but there is no report to date of temporomandibular joint (TMJ) lesions in this condition. We aimed to characterize the involvement of the TMJ in this uncommon bone disorder.Material and methods
We retrospectively included all patients managed for craniofacial forms of GS in our pediatric institution over a period of 12 years. We collected clinical data on TMJ function and radiological data from computed tomography and magnetic resonance imaging.Results
Four pediatric patients were managed for craniofacial forms of GS between 2005 and 2017. All patients presented with various radiological lesions of the TMJs, including osteolytic lacunae of the condylar head, condylar head flattening and thinning of the glenoid cavity. Only one patient presented with functional TMJ impairment.Conclusion
The TMJ appears to be radiology affected in pediatric craniofacial forms of GS. Nevertheless, TMJ lesions, even when radiologically severe, rarely impair TMJ function. TMJ structure and function should be systematically assessed in craniofacial forms of GS, and, in the case of joint lesions, a regular follow-up of TMJ function should be considered. 相似文献7.
Bruno Ramos Chrcanovic Ricardo Santiago Gomez 《Journal of cranio-maxillo-facial surgery》2018,46(3):504-510
Purpose
To integrate the available data published on squamous odontogenic tumors (SOT) and squamous odontogenic tumor-like proliferations in odontogenic cysts (SOT-LPOC) into a comprehensive analysis of their clinical/radiologic features.Materials and methods
An electronic search was undertaken in January 2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm a definite diagnosis.Results
A total of 74 publications reporting 110 SOTs (102 central, 8 peripheral) and 60 SOT-LPOC were included. Compared to SOT-LPOC, SOT showed lower mean age, no preference regarding maxilla or mandible localization, significant association with cortical bone perforation, multilocular radiographic appearance, and mobility of the tooth/teeth associated with the lesion. While 5 recurrent SOT were reported after enucleation, no recurrent SOT-LPOC was found.Conclusions
SOT shows a more aggressive biologic behavior than SOT-LPOC, which supports the hypothesis that the two lesions are distinct clinicopathological conditions. 相似文献8.
Karina Morais Faria Ana Carolina Prado Ribeiro Thais Bianca Brandão Wagner Gomes Silva Marcio Ajudarte Lopes Juliana Pereira Marcelo Corrêa Alves Luiz Alcino Gueiros Werner Harumiti Shintaku Cesar Augusto Migliorati Alan Roger Santos-Silva 《Journal of the American Dental Association (1939)》2018,149(5):382-391
Background
The purpose of this study was to evaluate whether intravenous (IV) bisphosphonate (BP) therapy can change the radiographic patterns of multiple myeloma (MM) in the jawbones.Methods
The authors evaluated panoramic radiographs obtained from 188 patients with MM for the presence of solitary osteolytic lesions, multiple osteolytic lesions, diffuse osteoporosis, diffuse sclerosis, lamina dura abnormalities, nonhealing alveolar sockets, and bone sequestration. The authors compared results obtained from patients treated with IV BPs with those obtained from patients who had never been exposed to BPs.Results
Multiple osteolytic lesions (P = .001), diffuse osteoporosis (P = .001), and diffuse sclerosis (P = .0036) occurred more often in the mandible in both groups. Solitary osteolytic lesions occurred less frequently in the BP group (P = .0078). Lamina dura abnormalities (P = .0006) and nonhealing alveolar sockets (P = .0021) were associated with BP treatment.Conclusions
IV BP therapy changes the radiographic patterns of MM in the jawbones.Practical Implications
The effect of BPs in the maxillofacial area is a matter of concern for health practitioners because this type of medication causes several alterations of the jawbones in patients with cancer. 相似文献9.
Dario Di Nardo Gianluca Gambarini Silvia Capuani Luca Testarelli 《Journal of endodontics》2018,44(4):536-542
Introduction
This review analyzes the increasing role of magnetic resonance imaging (MRI) in dentistry and its relevance in endodontics. Limits and new strategies to develop MRI protocols for endodontic purposes are reported and discussed.Methods
Eligible studies were identified by searching the PubMed databases. Only original articles on dental structures, anatomy, and endodontics investigated by in vitro and in vivo MRI were included in this review. Original articles on MRI in dentistry not concerning anatomy and endodontics were excluded.Results
All the consulted studies showed well-defined images of pathological conditions such as caries and microcracks. The enhanced contrast of pulp provided a high-quality reproduction of the tooth shape and root canal in vitro and in vivo. Assessment of periapical lesions is possible even without the use of contrast medium.Conclusions
MRI is a nonionizing technique characterized by high tissue contrast and high image resolution of soft tissues; it could be considered a valid and safe diagnostic investigation in endodontics because of its potential to identify pulp tissues, define root canal shape, and locate periapical lesions. 相似文献10.
K. Siva sankar K. Pranitha A.J. Sai Sankar B. Sujatha V. Sai krishna K. Kiran kumar 《Pediatric Dental Journal》2018,28(3):160-164
Background
Remineralizing agents are found to be effective in the remineralization of early enamel caries and the remineralized enamel crystallites are more resistant to decalcification and also have the same orientation as the original enamel crystallites. Although child formula fluoridated dentifrices are used safely by young children their remineralizing capability remains questionable.Aim
To evaluate the remineralizing potential of three commercially available pediatric dentifrices on artificial carious lesions in primary teeth.Materials and methods
A total of fifty sound human primary teeth were coated with nail varnish leaving a window of 2 mm × 4 mm on buccal surface and were subjected to demineralization for a period of 96 h and then sectioned. Out of the hundred sections obtained, ninety sections are equally divided into three groups with thirty in each group: Group I (Colgate Spider man), Group II (Kids bunny), Group III (Kidodent) subjected to remineralization respectively for 10 days using pH cycling model. The sections were then evaluated under the stereomicroscope for the remineralization values using MICAP image analyser software.Results
Statistical analysis was done by using ANOVA test which showed that all the three dentifrices showed remineralization with artificial carious lesions. Among the three test groups, Group I showed higher remineralization potential compared with the other two pediatric dentifrices which was statistically significant (p < 0.05).Conclusion
All the three dentifrices demonstrated remineralization of carious lesions by virtue of decrease in lesion depth. 相似文献11.
Introduction
The success of periodontal and endodontic treatments depends on the total recovery from both conditions regardless of their occurrence as independent or combined lesions. There is strong presumptive evidence that teeth with periodontal disease may cause pulpal inflammation and degeneration. Therefore, the goal of this study was to establish a correlation between periodontitis and pulp volume.Methods
Thirty-four dental images from 17 patients obtained by cone-beam computed tomography were analyzed by medical software to create three-dimensional images. Paired t test analysis was used for statistical analysis.Results
The statistical analysis showed that periodontitis had a significant effect on the volume and surface areas of the dental pulp (P < .05).Conclusions
The findings of this study showed that periodontitis causes pulp volume to reduce by approximately 20%. The use of three-dimensional models provides better understanding of the dental anatomy before endodontic treatment and, consequently, improvement of treatment outcomes. Additional studies are needed to investigate the effect of periodontal disease on pulp volume and surface area. 相似文献12.
María Peñarrocha-Diago Isabel Menéndez-Nieto Juan Cervera-Ballester Laura Maestre-Ferrín Juan Antonio Blaya-Tárraga David Peñarrocha-Oltra 《Journal of endodontics》2018,44(8):1205-1209
Introduction
Several variables have been associated with a better prognosis of periapical surgery. The aim of this study was to evaluate the influence of 2 hemostatic agents on the prognosis of periapical surgery at 12 months.Methods
A prospective study was designed with 2 randomized parallel groups established depending on the hemostatic agent used: epinephrine or aluminum chloride. The analysis of the hemorrhage control was recorded as 0 (no hemorrhage control), 1 (slight but apparent intermittent bleeding persisted after application of the material), or 2 (complete hemorrhage control). At 12 months, periapical lesion healing was determined clinically and radiologically as success, improvement, or failure.Results
Ninety-five patients (67 women and 28 men) with periapical lesions involving a single tooth were enrolled in this study; in 45 teeth, epinephrine was used and in 50 teeth aluminum chloride. In the epinephrine group, 28 teeth were classified as successes, 10 as improvements, and 7 as failures. In the aluminum chloride group, 34 teeth were classified as successes, 11 as improvements, and 5 as failures. No statistically significant difference was found.Conclusions
The present study found no association between the use of epinephrine or aluminum chloride as hemostatic agents on the prognosis of periapical surgery. The efficacy of hemostatic agents at the time of surgery showed no relationship with the healing outcome. 相似文献13.
Daniel Kruber Thomas Hierl Hans-Martin Doerfler Heike Huempfner-Hierl Matthias Krause 《Journal of cranio-maxillo-facial surgery》2018,46(7):1159-1161
Introduction
Polydioxanone (PDS) sheets are commonly used in the treatment of orbital wall fractures. A potential drawback of PDS is that it may be difficult to adapt to the anatomy of the orbital walls. Therefore a study was conceived to test the feasibility of preforming PDS sheets.Material and methods
PDS sheet material was water-heated and preformed using a template based on a statistical anatomical model. Then the deformed sheet was cooled, stored and compared to the original model to investigate post-deformation changes.Results
PDS sheet material could easily be deformed using a mould. No significant post-cooling shape changes were noticed.Conclusions
PDS sheet material can be preformed into complex geometric shapes. This could be a benefit in the treatment of orbital wall fractures. 相似文献14.
Raymond A. Kuthy Susan C. McKernan Mark Pooley M. Bridget Zimmerman 《Journal of the American Dental Association (1939)》2018,149(4):308-316
Background
In this study, the authors used observational data from 2014 to evaluate the association between the number of general dentists and several community characteristics.Methods
The authors collected community-level characteristics from secondary sources for all 947 Iowa incorporated communities to study their relationships with the mean number of general dentists per 1,000 population per square mile (population density), the dependent variable. The authors used zero-inflated negative binomial models to examine the association between the dependent and predictor variables.Results
Only 22.8% of communities had a dentist. Urban, young, well-educated, fluoridated communities with at least 1 elementary school had the highest estimated mean concentration of dentists. Isolated communities with older, less educated adults and lacking fluoridation and an elementary school had the fewest dentists.Conclusions
Although population is an important determinant for where a dentist practices, other variables such as urbanization, demographic characteristics, fluoridation status, and presence of at least 1 elementary school are also predictors of the number of dentists in a community.Practical Implications
These findings provide dental students and young practitioners useful information by highlighting community characteristics that are associated with office locations. 相似文献15.
Jochen Weitz Klaus-Dietrich Wolff Marco Rainer Kesting Christopher-Philipp Nobis 《Journal of cranio-maxillo-facial surgery》2018,46(11):1975-1978
Introduction
The authors developed a semi-standardised resection and cutting guide for mandibular reconstruction with free fibula flap based on data of mandible sizes and angles.Methods
After analyzing the angles and lengths of mandibular angles and segments on computer tomography, a partly-adjustable resection guide for the mandible and cutting guide for the fibula were designed.Results
After testing and optimizing the guides on plastic models and cadavers, the guides were successfully used for mandible resection and reconstruction with free fibula flap in 8 patients with segmental mandibulectomy. Application of the cutting and resection guides and functional results like occlusion and aesthetic appearence were satisfactory in all cases.Conclusions
The developed semi-standardised device is a helpful instrument for facilitating reconstruction of segmental mandibular defects with free fibula flaps. No extensive preoperative preparation and 3D printing is necessary which can avoid additional costs for virtual planning. Especially for lower budget health systems this can be an alternative to virtual planning. 相似文献16.
Samer George Hakim Ali Shakery Tehrany Robert Wendlandt Hans-Christian Jacobsen Thomas Trenkle Peter Sieg 《Journal of cranio-maxillo-facial surgery》2018,46(11):1939-1942
Purpose
The fibula flap has been established for orofacial reconstruction following ablative surgery. Donor-site morbidity of the lower leg may be explained by the harvest technique and particularly by detachment of the M. extensor halluces longus (EHL) and M. extensor digitorum longus (EDL).Material and methods
On cadaveric lower leg specimens, the tendons of the EHL and EDL were dissected at the proximal phalanges and loaded with corresponding weights. The average displacement of the muscle was evaluated during the harvesting procedure.Results
Cumulative detachment of the interosseous membrane caused considerable displacement of the EHL but less impairment of the EDL. Segmental and cumulative osteotomy of the fibula implicated significant displacement of both EHL and EDL.Conclusion
A recommendation can be given for cautious selection of osteotomy site of the fibula and for limited sacrifice of the fibula and adjacent attachments of the extensors to keep local-site morbidity at a minimum. 相似文献17.
Natalia Martínez-Rodríguez Cristina Barona Dorado Jorge Cortés-Bretón Brinkmann María Martín Ares Javier Sanz Alonso José Maria Martínez-González 《Journal of the American Dental Association (1939)》2018,149(11):976-982
Background
Maxillary sinus carcinoma is a rare entity with an incidence of 0.2% and a low patient survival rate due to the frequency of late diagnosis.Methods
In this multicenter, transversal, retrospective, observational study, the authors analyzed patients who had received a diagnosis of maxillary sinus carcinoma, registering their oral symptoms, histologic type, treatment efficacy, and survival rate.Results
Maxillary sinus carcinoma was diagnosed in 24 patients (15 men and 9 women), of which 75% were squamous cell carcinomas. All patients had dental mobility, and some had swelling, orosinus fistula, or some dental loss. Mean patient survival rate was 38.83 months.Conclusions
A history of pain or swelling of unknown origin, an unexplained widening of periodontal ligament space, or mobility of the teeth should be considered warning signs of maxillary sinus carcinoma.Practical Implications
Recognition of oral symptoms by the dentist would help in making an early diagnosis of maxillary sinus carcinoma, improving the patient’s chances of survival and quality of life. 相似文献18.
19.
Filippo Giovannetti Federico Mussa Paolo Priore Mirko Scagnet Elena Arcovio Valentino Valentini Lorenzo Genitori 《Journal of cranio-maxillo-facial surgery》2018,46(12):2017-2021
Object
At present, a minimally invasive endoscopic endonasal approach is considered an efficient option for lesions affecting the anterior and middle skull base with sellar and parasellar region involvement. In this study we will retrospectively analyze the pediatric patients that we have been treating in the same medical center for the past four years, using an endoscopic approach in the skull base.Methods
We performed a retrospective chart and imaging review of pediatric patients who underwent endoscopic endonasal skull base surgery (ESBS) at the Meyer Children's Hospital, (Azienda Ospedaliero Universitaria Meyer), in Florence, from January 2012 to July 2016.Results
Mean age was 12,5 years; 28 (65%) of the 44 patients were females. Skull base lesions were broadly classified as either bony abnormalities (4 cases) or skull base tumors (40 cases). The postoperative clinical follow-up duration ranged from 2 to 36 months. The two more frequently occurring diseases in our study were: craniopharyngioma and pituitary adenoma.Conclusions
After reviewing the international literature about pediatric endoscopic endonasal approach to skull base, we can affirm that our study is the world's second broadest work for number of records. While compiling this report, we have examined the first 40 consecutive pediatric patients to undergo ESBS at our institute. The appearance of postoperative complications is consistent with other international studies, confirming ESBS being feasible and safe even in the pediatric population.Level of evidence
4. 相似文献20.
Rebecca L. Slayton Olivia Urquhart Marcelo W.B. Araujo Margherita Fontana Sandra Guzmán-Armstrong Marcelle M. Nascimento Brian B. Nový Norman Tinanoff Robert J. Weyant Mark S. Wolff Douglas A. Young Domenick T. Zero Malavika P. Tampi Lauren Pilcher Laura Banfield Alonso Carrasco-Labra 《Journal of the American Dental Association (1939)》2018,149(10):837-849.e19