软骨样汗管瘤

组织病理特征本文2张组织病理图片的主要特征为真皮内可见界限清楚的团块,团块内有较多小的导管及囊腔样结构.在管样结构之间可见大量黏液样间质,内有软骨样细胞及梭形的成纤维细胞.     

足部软骨样汗管瘤

报告1例足部软骨样汗管瘤。患者男,68岁。左足背外缘肿物1年余。皮肤科检查:左足背外缘一1.5 cm×2.0 cm圆形粉红色结节,无触痛,基底部边缘皮肤呈灰白色伴增厚。皮损组织病理检查:真皮内可见大量由细胞核小及胞质丰富的立方形上皮细胞形成的条索状或领带状结构,基质呈淡蓝色软骨样或嗜酸性透明样。阿辛蓝染色示黏蛋白沉积。免疫组化:癌胚抗原(CEA)、上皮膜抗原(EMA)、细胞角蛋白广谱抗体(AE1/AE3)及S-100蛋白均阳性。诊断:良性软骨样汗管瘤(皮肤混合瘤)。治疗:予手术切除,随访至今未复发。     

眉弓部软骨样汗管瘤

报告1例眉弓部软骨样汗管瘤.患者男,88岁.因右眉弓反复出现肿块10年就诊.皮损组织病理检查:真皮基质由无腔隙的上皮细胞堆积,可见黏液性、软骨样、脂肪细胞样物质.诊断:软骨样汗管瘤.     

下颌肤色结节——软骨样汗管瘤

诊断:软骨样汗管瘤. 皮损组织病理检查:皮下组织中限局性肿瘤,嗜碱性的结节性基质中,可见上皮细胞构成的不规则囊腔和管腔.囊壁由二三层复层立方上皮构成,囊腔内见丰富的嗜碱性黏液样和假软骨性基质.免疫组化组织病理:管腔内外层细胞低分子质量角蛋白(CK)阳性,管腔内层细胞上皮细胞膜抗原(EMA)阳性、癌胚抗原(CEA)阳性.     

表现为多发性斑块的软骨样汗管瘤

报告1例罕见的多发性软骨样汗管瘤。患者男,36岁。右跖部褐色斑块2年,手部褐色斑块1年,均伴有局部疼痛。经组织病理检查诊断为软骨样汗管瘤。采用雷公藤多苷治疗有效。     

粟丘疹样汗管瘤

患者女,64岁。主诉:外阴多发丘疹1年。现病史:患者1年前无明显诱因双侧大阴唇多发肤色丘疹,伴轻度瘙痒,渐增多。曾予外用糖皮质激素治疗,皮损无明显消退。为明确诊断,遂于2017年4月11日来我科就诊。既往史及家族史:患者10年前行子宫切除术。家族中无类似疾病患者。体格检查:各系统检查均正常。皮肤科检查:双侧大阴唇多发粟粒大肤色丘疹,部分丘疹表面有蜡样光泽,不融合(图1),质坚实。左侧大阴唇皮损组织病理检查:表皮轻度角化过度,棘层轻度肥厚,真皮浅层可见数个角囊肿,其下可见大小不一的嗜碱性导管、囊腔及条索结构(图2A);细胞条索呈蝌蚪状或逗点状,导管和囊腔均由2层上皮组成,腔内为嗜酸性无定形物(图2B)。     

少见部位汗管瘤1例

报告1例少见部位的发疹型汗管瘤。患者女,23岁,四肢出现粟粒到米粒大小的丘疹两年,无自觉症状。皮肤组织病理检查符合汗管瘤特征。     

毛囊角化病样发疹性汗管瘤1例

患者男, 45岁。四肢皱褶部位多发性褐红色小丘疹 5年,依靠组织病理学的特异性表现确诊为发疹性汗管瘤。     

Malignant Chondroid Syringoma

Malignant chondroid syringoma (MCS) is a rare tumor, of the sweat gland; only a few hundred such cases are reported in literature. A female presented with a subcutaneous swelling on the scalp with repeated recurrence and positive regional lymph nodes. Adequate planning for the treatment of this case was possible as preoperative diagnosis of MCS was documented by fine needle aspiration cytology (FNAC). The case was successfully managed with a multimodal approach, which included radical surgery and subsequent radiotherapy. The patient is symptom free after 25 months. The possibility of this type tumor should be entertained when multiple recurrences occur following adequate excision. FNAC has a definitive role in planning rational therapy.     

Unusual Cases of Syringoma of the Forehead

Syringoma involving the forehead is rare and can be confused with other diseases that are common on the forehead. Therefore, we describe here three patients with syringoma who developed numerous skin colored papules on the forehead. To our knowledge, syringoma of the forehead was reported previously only once by Tagami et al.     

Syringoma of the face treated with fractional photothermolysis

Abstract

We experienced that two Japanese women diagnosed with syringoma, confirmed by a punch biopsy, were successfully treated with fractional resurfacing. Both clinical cases have had positive results after only a few treatments, with high patient satisfaction, not only for the improvement of syringoma, but also for the improvement of aging skin, and with no side effects. From that aspect, laser treatment with fractional photothermolysis may be considered to be one of the effective treatment methods for syringoma. Although fractional photothermolysis was originally developed for an aesthetic purpose, it also can be utilized for intractable skin disease, as demonstrated by taking the concept of fractional photothermolysis and the results from this study with skin biopsy.     

A Case of Unusual Syringoma: Unilateral Linear Distribution and Plaque Formation

We describe a 25-year-old woman with syringoma, clinically manifested by unilateral linear distribution and a plaque formation. Syringoma papules are located on the extensor aspect of the left upper arm, the left antecubital fossa, and the left side of the chest. The papules distributed in linear fashion on the left upper arm, and partially formed plaques on the left upper arm and the left antecubital fossa. Syringoma must be included in the differential diagnosis of unilateral linear papular or plaque skin lesions.     

Chondroid Syringoma of the Forearm: A Case Report of a Rare Localization

Chondroid syringoma (CS) is an uncommon benign adnexal tumor of the skin with eccrine and apocrine origin, which usually involves the head and neck region. The presentation of CS in other areas of the body is rare. A 45-year-old male patient presented to the dermatology clinic with a chief complaint of a painless, slow-growing mass on his left forearm, which gradually developed over the course of 2 years. A solitary, firm, purple, mobile, non-tender nodule was located in the distal part of left dorsal forearm, which was 1.8 cm in diameter. The tumor was surgically excised and sent for the histopathological evaluation. Results of biopsy and hematoxylin and eosin staining confirmed the diagnosis of CS and showed no evidence of malignancy. Although CS is an uncommon tumor in uppr limb region, it should be considered as one of the differential diagnoses, when dealing with tumors of this area.     

表现为粟丘疹的汗管瘤

报告1例表现为粟丘疹的汗管瘤。患儿女,9岁,面部、颈部、双侧腋窝、胸部、下腹部和外阴部出现许多肤色或白色丘疹4年。临床上皮损类似于粟丘疹。皮损组织病理检查示真皮浅层有数个角囊肿,其下方真皮纤维基质中有许多囊性管腔和实性上皮细胞条索。