烧伤创疡再生医疗技术治疗电烧伤的临床疗效观察

目的探讨分析烧伤创疡再生医疗技术治疗电烧伤创面的临床疗效。方法给予2012年3月至2019年10月静海区中医医院烧伤科收治的115例电烧伤患者抗休克、抗感染等全身综合治疗的同时,局部创面应用湿润烧伤膏换药治疗,观察治疗效果。结果 115例患者均痊愈出院,创面愈合时间为10～90 d,其中,8例行钻孔术治疗的骨外露患者中有3例患者创面仅采用湿润烧伤膏换药治疗后即在短期内愈合,13例肌腱坏死、8例肌腱外露患者创面均于湿润烧伤膏换药治疗后在短期内愈合,其余患者创面均于皮瓣移植或植皮封闭后愈合。结论烧伤创疡再生医疗技术可有效促进电烧伤创面愈合,疗效显著,且操作简便,临床应用价值较高。     

湿润烧伤膏治疗唇周单纯疱疹30例疗效观察

目的观察、探讨湿润烧伤膏治疗唇周单纯疱疹的临床疗效。方法对30例唇周单纯疱疹患者采用湿润烧伤膏换药治疗,每日2~4次,观察疱疹创面愈合情况。结果 30例患者的局部疱疹创面均在换药治疗24 h后明显减轻,平均治疗3 d后,局部肿胀及渗出完全消退,破损创面完全愈合。结论湿润烧伤膏治疗唇周单纯疱疹疗效好、愈合快、操作简便,值得临床推广应用。     

头皮广泛缺损伴部分颅骨外露坏死的治疗效果观察

目的:观察软组织缺损、颅骨外露伴部分坏死的非手术治疗效果.方法:美宝湿润烧伤膏和其它中药联合使用予创面换药,修复软组织缺损、颅骨外露伴部分坏死的创面,其中烧伤2例,电击伤1例,头皮撕脱伤2例.结果:5例患者创面愈合满意.结论:美宝湿润烧伤膏和其它中药联合使用是治疗头皮广泛缺损伴部分颅骨外露坏死的理想方法.     

湿润烧伤膏治疗糖尿病足的临床体会

目的 探讨湿润烧伤膏治疗糖尿病足的效果.方法 对56例糖尿病足创面应用MEBO包扎治疗,每日换药1次,并发感染的创面4 h换药1次.结果 56例患者中有53例创面自行愈合,3例因创面较大较深,经抗感染治疗后行截肢或截趾治疗.结论 湿润烧伤膏对糖尿病足有较好的治疗效果.     

湿润烧伤膏治疗压疮的疗效与护理

目的探讨湿润烧伤膏治疗压疮的临床疗效与护理对策。方法 48例压疮患者创面全部采用湿润烧伤膏换药治疗,根据创面情况分别采取暴露疗法和包扎疗法,暴露疗法者每日换药4~6次,包扎疗法者每日换药1次,观察创面愈合效果。结果 48例患者中痊愈39例,好转9例,总有效率达100%。结论湿润烧伤膏具有保护创面,为创面持续营造湿润、微酸、洁净环境等作用,可促进压疮创面愈合。     

复杂肛瘘术后外用湿润烧伤膏疗效分析

目的:观察湿润烧伤膏(MEBO)对复杂肛瘘术后的治疗疗效.方法:54例复杂肛瘘术后患者,于术毕用湿润烧伤膏纱条填塞创面,压迫止血,48小时取出纱条,以后用湿润烧伤膏涂于创面内,每12小时1次,直至痊愈.结果:复杂肛瘘术后创面外用湿润烧伤膏换药,无出血、感染及肛门失禁,疼痛轻,创面愈合时间缩短.结论:湿润烧伤膏是复杂肛瘘术后理想的局部治疗药物.     

湿润烧伤膏治疗跟骨骨折术后钢板外露疗效观察

目的探讨湿润烧伤膏(moist exposed burn ointment,MEBO)治疗跟骨骨折术后内固定钢板外露的临床疗效。方法将2015年1月—2016年6月河南宏力医院骨科收治的35例跟骨骨折术后内固定钢板外露患者随机分为观察组(19例)与对照组(16例),观察组患者采用湿润烧伤膏换药治疗,对照组患者采用常规换药治疗,对比观察两组患者的临床疗效。结果两组患者创面均完全愈合,其中观察组患者的创面愈合时间为11~27 d,明显短于对照组的19~38 d。治疗21 d后,观察组患者的总有效率为94.74%,明显高于对照组的56.25%,P0.05,差异具有统计学意义,即湿润烧伤膏治疗跟骨骨折术后内固定钢板外露的临床疗效明显优于传统疗法。结论湿润烧伤膏治疗跟骨骨折术后内固定钢板外露,创面愈合时间较短,疗效显著,值得临床推广应用。     

湿润烧伤膏与皮瓣移植序贯治疗足踝部软组织缺损感染伴骨外露效果观察

目的探讨湿润烧伤膏与皮瓣移植序贯治疗足踝部软组织缺损感染伴骨外露的临床疗效。方法对2015年1月至2018年1月武警黑龙江省总队医院收治的26例足踝部软组织缺损感染伴骨外露患者的局部创面实施湿润烧伤膏与皮瓣移植序贯治疗,观察治疗效果。结果皮瓣移植术后,20例患者移植皮瓣完全成活,创面一期愈合,无张力性水疱、肿胀、静脉回流障碍、感染等并发症发生;6例患者移植皮瓣边缘部分坏死,予以湿润烧伤膏换药治疗后愈合。随访0.5～3.5年[(1.5±0.5)年],移植皮瓣柔软有弹性,足踝部功能恢复良好,无局部发凉等异常感觉。结论湿润烧伤膏与皮瓣移植序贯治疗足踝部软组织缺损感染伴骨外露,可有效促进创面肉芽组织生长及创面一期愈合,疗效满意。     

MEBO治疗手足皮肤剥脱伤的临床体会

目的探讨湿润烧伤膏联合创疡贴治疗手足皮肤剥脱伤的临床疗效。方法 8例不同程度的手足皮肤剥脱伤患者创面清创缝合后应用湿润烧伤膏联合创疡贴治疗,每日换药1次,直至创面愈合,观察治疗效果。结果所有创面均于治疗45~60 d后愈合,平均愈合时间为50.2 d;随访3~14个月,愈后皮肤平整,无明显瘢痕增生,弹性和功能恢复良好。结论湿润烧伤膏联合创疡贴治疗手足皮肤剥脱伤疗效确切,值得临床推广应用。     

遗传性大疱性表皮松解症1例报告

对2017年12月南方医科大学皮肤病医院皮肤科收治的1例遗传性大疱性表皮松解症患儿局部皮损创面采用夫西地酸乳膏、复方多粘菌素B乳膏、湿润烧伤膏混合物换药治疗4 d后改为单纯应用湿润烧伤膏换药治疗,治疗10 d后,创面明显缩小,患儿出院,并于家中自行应用湿润烧伤膏换药治疗。出院后随访6个月,创面完全愈合,愈后皮肤仅留有少许色素沉着,无明显增生性瘢痕形成。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.