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1.
S O Schoenberg M Bock M V Knopp M Essig G Laub H Hawighorst I Zuna F Kallinowski G van Kaick 《Radiology》1999,211(3):667-679
PURPOSE: To compare two different three-dimensional (3D) gadolinium-enhanced magnetic resonance (MR) angiographic techniques. MATERIALS AND METHODS: In 26 patients suspected of having renal artery stenosis, results with fast multiphase 3D MR angiography were compared to those with standard 3D MR angiography in 37 patients. With both techniques, 31-second breath-hold acquisitions were performed. Multiphase angiography comprised five discrete 6.4-second acquisitions without bolus timing, and standard angiography comprised a single acquisition based on test-bolus timing. Two readers evaluated images obtained with both techniques in terms of image quality, artifacts, and vessel conspicuity. Accuracy of findings on the multiphase 3D MR angiograms for assessment of renal artery stenosis was determined by comparing them to digital subtraction angiograms and surgical findings. RESULTS: In the early arterial phase, multiphase 3D MR angiograms showed no image degradation by venous overlay, whereas standard 3D MR angiograms depicted at least minor overlay in 53 of 83 renal arteries (P < .001). Less parenchymal enhancement in the early arterial phase resulted in a higher vessel conspicuity for the divisions and segmental arteries (P < .001). Both readers detected and correctly graded 18 of 20 stenoses on the multiphase angiograms with almost perfect interobserver agreement (kappa > 0.89). CONCLUSION: Renal multiphase 3D MR angiography is an accurate technique requiring no bolus timing. The performance of early arterial phase imaging leads to improved depiction, particularly of the distal renovascular tree, compared to that with standard single-phase 3D MR angiography. 相似文献
2.
Assessment of gadolinium-enhanced time-resolved three-dimensional MR angiography for evaluating renal artery stenosis 总被引:3,自引:0,他引:3
Masunaga H Takehara Y Isoda H Igarashi T Sugiyama M Isogai S Kodaira N Takeda H Nozaki A Sakahara H 《AJR. American journal of roentgenology》2001,176(5):1213-1219
OBJECTIVE: The purpose of this study was to assess the image quality of gadolinium-enhanced time-resolved three-dimensional (3D) MR angiography and to evaluate its accuracy in revealing renal artery stenosis. SUBJECTS AND METHODS: Thirty-nine patients underwent MR angiography using an ultrafast 3D Fourier transform spoiled gradient-recalled acquisition in the steady state (TR/TE range, 2.6/0.7--0.8). Five seconds after administration of 15--20 mL gadodiamide hydrate, four or five consecutive data sets with imaging times of 7.0--7.6 sec were acquired during a single breath-hold. A timing examination was not performed. Image quality was assessed using quantitative analysis (signal-to-noise, contrast-to-noise, and venous-to-arterial enhancement ratios) and qualitative analysis (presence of venous overlap, presence of artifacts, and degree of renal arterial enhancement). MR angiography depiction of the renal artery stenosis was evaluated using conventional angiography as the standard of reference. RESULTS: On the best arterial phase, average aortic signal-to-noise ratio (+/-SD) was 74.5 +/- 24.4, aorta-to--inferior vena cava contrast-to-noise ratio was 70.8 +/- 23.4, and inferior vena cava--to-aorta venous-to-arterial enhancement ratio was 0.03 +/- 0.04. No venous overlap was seen in 38 of 39 patients. Substantial enhancement of renal arteries was seen in all patients without any noticeable artifacts. MR angiography correctly depicted the degree of stenosis in 44 of 47 normal arteries, 13 of 16 mildly stenotic arteries, five of five moderately stenotic arteries, three of four severely stenotic arteries, and one of one occluded artery. Sensitivity and specificity for revealing greater than 50% stenosis was 100%. CONCLUSION: Time-resolved 3D MR angiography can provide high-quality arteriograms. Its performance in revealing renal artery stenosis is comparable with that of conventional angiography. 相似文献
3.
Three-dimensional gadolinium-enhanced MR angiography: applications for abdominal imaging. 总被引:11,自引:0,他引:11
J F Glockner 《Radiographics》2001,21(2):357-370
Three-dimensional (3D) gadolinium-enhanced magnetic resonance (MR) angiography is a versatile technique that combines speed, superb contrast, and relative simplicity. It has a wide range of applications, particularly in the abdomen and pelvis, where superb images of the abdominal aorta and renal arteries are routinely obtained. Aneurysms, atherosclerotic lesions, and occlusions of the major mesenteric arteries are also well depicted. In addition, 3D gadolinium-enhanced MR angiography is ideal for noninvasive evaluation of the systemic and mesenteric veins and can be used to demonstrate parenchymal lesions in the liver, pancreas, kidneys, and other organs. It is also useful in staging genitourinary neoplasms: Parenchymal lesions, venous extension, and adenopathy are all clearly depicted. Three-dimensional gadolinium-enhanced MR angiography can be useful in the preoperative evaluation of potential transplant donors and recipients and in the evaluation of vascular complications following transplantation. Delayed 3D acquisitions of the kidneys, ureters, and bladder can be performed routinely to generate gadolinium-enhanced urograms and demonstrate obstruction, delayed function, filling defects, and masses. A variety of methods for increasing the speed and improving the resolution of 3D acquisition are currently under investigation. These include novel imaging and reformatting techniques and the use of intravascular contrast agents with much longer vascular half-lives. 相似文献
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Accuracy of three-dimensional gadolinium-enhanced MR angiography in the assessment of extracranial carotid artery disease 总被引:2,自引:0,他引:2
Serfaty JM Chirossel P Chevallier JM Ecochard R Froment JC Douek PC 《AJR. American journal of roentgenology》2000,175(2):455-463
OBJECTIVE: The purpose of this study was to assess three-dimensional (3D) gadolinium-enhanced MR angiography, used alone or in association with duplex Doppler sonography, with a fast acquisition time (8 sec) for evaluating the extracranial carotid arteries. SUBJECTS AND METHODS: In this prospective study, 48 successive patients with carotid artery stenoses were examined with 3D gadolinium-enhanced MR angiography and 3D time-of-flight MR angiography. Of the 44 eligible patients, conventional angiography was available in 33 and duplex sonography in 27. We used the North American Symptomatic Carotid Endarterectomy Trial technique to quantify stenosis on all angiograms, and a 250 cm/sec threshold at duplex sonography to diagnose stenoses greater than 70%. Image quality of 3D gadolinium-enhanced MR angiography and 3D time-of-flight MR angiography was assessed, as well as sensitivity and specificity for each technique alone and in combination with duplex sonography. Conventional angiography was the gold standard. RESULTS: Three-dimensional gadolinium-enhanced MR angiography yielded good image quality in 90% of cases. When used alone, it yielded a sensitivity and a specificity of 94% and 85%, respectively, in screening stenoses greater than 70% (70-99%). When combined with duplex Doppler sonography, it provided a 100% sensitivity and specificity for detection of stenoses between 70% and 99% and would have obviated 61% of conventional angiography. In comparison, 3D time-of-flight MR angiography used alone yielded a sensitivity of 88% and a specificity of 94%. In combination with duplex Doppler sonography, its use would have obviated conventional angiography in 74% of cases. Three-dimensional gadolinium-enhanced MR angiography provided accurate results in the diagnosis of occlusions and ulcers and can visualize distant stenoses. CONCLUSION: Used alone, 3D gadolinium-enhanced MR angiography is not accurate enough to replace conventional angiography in the evaluation of extracranial carotid arteries. In association with duplex Doppler sonography, however, it is accurate and may obviate a significant number of conventional angiographic examinations. 相似文献
5.
Evaluation of dynamic gadolinium-enhanced breath-hold MR angiography in the diagnosis of renal artery stenosis. 总被引:2,自引:0,他引:2
M J Thornton F Thornton J O'Callaghan J C Varghese E O'Brien J Walshe M J Lee 《AJR. American journal of roentgenology》1999,173(5):1279-1283
OBJECTIVE: The aim of our study was to evaluate a three-dimensional gadolinium-enhanced breath-hold MR angiography sequence using standard MR gradients in detecting renal artery stenosis. SUBJECTS AND METHODS: Forty-two patients referred for angiography for suspected renal artery stenosis underwent both conventional digital subtraction angiography (DSA) and MR angiography. MR angiography was performed on a 1.5-T scanner with standard gradients. A fast multiplanar spoiled gradient-echo sequence was used with the following parameters: TR/TE, 10.3/1.9; flip angle, 45 degrees; field of view, 36 x 32 cm; matrix size, 256 x 128; one excitation; volume thickness, 70 mm; and partitions, 28. Gadolinium was administered IV as a dynamic bolus of 30-40 ml. Conventional and MR angiographic images were interpreted by two radiologists in consensus. RESULTS: DSA revealed 87 renal arteries, of which 79 were in 35 patients with native kidneys and eight arteries were in seven patients with transplanted kidneys. Gadolinium-enhanced MR angiography showed 85 (98%) of 87 renal arteries. Seventeen patients had 20 significant (>50% stenosis) renal artery stenoses and five patients had five occluded renal arteries revealed by DSA. MR angiography revealed 85 renal arteries (98%), 20 stenoses (100%), and five occlusions (100%). Gadolinium-enhanced MR angiography led to one false-positive interpretation for renal artery stenosis and no false-negative interpretations. Thus, the sensitivity, specificity, and accuracy of MR angiography for renal artery stenosis were 100%, 98%, and 99%, respectively. CONCLUSION: The MR angiography pulse sequence we used was an effective and reliable technique for the diagnosis of renal artery stenosis. The sequence can be performed on widely available MR equipment that does not require fast gradient hardware. 相似文献
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Assessment of renal artery stenosis: comparison of captopril renography and gadolinium-enhanced breath-hold MR angiography 总被引:3,自引:0,他引:3
AIM: To determine the accuracy of captopril renography (CR) and gadolinium-enhanced breath-hold magnetic resonance (MR) angiography in the diagnosis of 50-99% renal artery stenosis (RAS). MATERIALS AND METHODS: Forty-three patients with possible RAS, of whom 53% had renal function impairment (creatinine >130 micromol/l), were included.(99m)Tc-mercaptoacetyl triglycine (MAG(3)) renography was performed after an oral dose of 25 mg captopril. Gadolinium-enhanced MR angiography was performed on a standard 1.5 Tesla system: TR 13.5, TE 3.5, flip angle 60 degrees, matrix 195 x 512. Intra-arterial digital subtraction angiography (DSA) was the standard of reference. RESULTS: Captropril renography accurately categorized 22 of 26 patients who had either uni- or bilateral RAS of 50-99%. The sensitivity and specificity of CR for the detection of 50-99% stenosis were 85 and 71%, respectively. With MR angiography one occluded artery was incorrectly diagnosed as a stenosis. Sensitivity and specificity were 100 and 94%, respectively. The difference between the accuracies of MR angiography and CR was statistically significant (P = 0.02). The accuracy of CR was lower in patients with renal impairment (70%) than in those with normal renal function (90%).CONCLUSION: MR angiography showed a high accuracy in diagnosing RAS of between 50 and 99%. CR was less accurate than MR angiography, especially in patients with renal function impairment. In patients with normal renal function, however, CR remains a useful diagnostic test. 相似文献
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Reed A Omary Kevin P Henseler Orhan Unal Lawrence J Maciolek J Paul Finn Debiao Li Albert A Nemcek Robert L Vogelzang Thomas M Grist 《AJR. American journal of roentgenology》2002,178(1):119-123
OBJECTIVE: Catheter-based intraarterial injections of gadolinium are useful during MR imaging-guided endovascular procedures to generate rapid vascular road maps. Using an animal model of renal artery stenosis, we tested the hypothesis that intraarterial gadolinium-enhanced MR angiography is as accurate as IV gadolinium-enhanced MR angiography and digital subtraction angiography (DSA). We also tested the hypothesis that intraarterial MR angiography uses less gadolinium than IV MR angiography. MATERIALS AND METHODS: We induced bilateral renal artery stenosis in five pigs. All pigs underwent comparative imaging with DSA, IV MR angiography, and aortic catheter-directed intraarterial MR angiography. For IV and intraarterial MR angiography, we used the same three-dimensional acquisition. We assessed differences in quantitative stenosis measurements among DSA, IV MR angiography, and intraarterial MR angiography using the Wilcoxon's signed rank test. RESULTS: Mean stenosis measurements (+/-SD) were as follows: DSA, 58% +/- 12%; IV MR angiography, 63% +/- 9.3%; and intraarterial MR angiography, 64% +/- 11%. There were no statistically significant differences in accuracy between DSA and IV MR angiography (p = 0.06), DSA and intraarterial MR angiography (p = 0.16), or IV and intraarterial MR angiography (p = 0.70). Intraarterial MR angiography used a mean gadolinium dose of 5.6 mL, compared with 9 mL for IV MR angiography. CONCLUSION: In swine, IV and intraarterial MR angiography have a similar accuracy for detecting renal artery stenosis. Intraarterial MR angiography uses smaller doses of injected gadolinium. 相似文献
10.
PURPOSE: To compare the accuracy of multisection true fast imaging with steady-state precession (FISP) with gadolinium-enhanced magnetic resonance (MR) angiography for the detection of coronary artery bypass graft patency. MATERIALS AND METHODS: Twenty-five patients with coronary artery bypass grafts who had recently undergone conventional coronary angiography underwent MR angiography with a 1.5-T system. True FISP angiographic images were acquired in transverse and coronal planes. Coronal cardiac-gated MR angiography was performed with 0.2 mL per kilogram of body weight of gadopentetate dimeglumine injected at a rate of 2 mL/sec. With conventional angiography as the reference standard, the sensitivity, specificity, and accuracy of each technique for the detection of graft patency were determined. Image quality and duration of analysis were determined by two experienced radiologists. RESULTS: In 25 patients, 46 of 56 venous grafts were patent and 22 of 23 arterial grafts were patent. In all grafts at true FISP angiography, sensitivity for patency was 84% (57 of 68 grafts), specificity was 45% (five of 11 grafts), and accuracy was 78% (62 of 79 grafts). At MR angiography, sensitivity was 85% (58 of 68 grafts), specificity was 73% (eight of 11 grafts), and accuracy was 84% (66 of 79 grafts) (difference not significant). Image quality scores were similar with both techniques, but duration of analysis was significantly longer with MR angiography than with true FISP angiography (29 minutes 24 seconds vs 14 minutes 6 seconds, P <.001). CONCLUSION: Accuracy for detection of coronary artery bypass graft patency was similar with gadolinium-enhanced MR angiography and true FISP angiography, with a trend toward more false-positive findings for occlusion and reduced visualization of arterial grafts with true FISP angiography. 相似文献
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Kim T Murakami T Takahashi S Hori M Takahara S Ichimaru N Okuyama A Narumi Y Nakamura H 《Radiation Medicine》2006,24(9):617-624
Purpose The purpose of this study was to clarify and compare the accuracy of contrast-enhanced computed tomography (CT) angiography
using multidetector-row helical CT (MDCT angiography) and gadolinium-enhanced MR angiography using three-dimensional Fourier
transformation gradient-echo sequence (3D MR angiography) for preoperative evaluation of renal arteries in living renal donors.
Materials and methods A total of 42 living renal donor candidates underwent both MDCT angiography and 3D MR angiography before digital subtraction
angiography (DSA). Each MDCT angiogram and 3D MR angiogram was prospectively interpreted, and the findings were compared with
the DSA results.
Results MDCT angiography identified all of the 12 supernumerary arteries detected by DSA, whereas 3D MR angiography identified only
8. MDCT angiography identified all of the 19 proximal arterial branches detected by DSA, whereas 3D MR angiography identified
only 16.
Conclusion A more accurate depiction of renal arteries in living renal donors can be achieved with MDCT angiography than with 3D MR angiography. 相似文献
13.
Equilibrium-phase MR angiography of the aortoiliac and renal arteries using a blood pool contrast agent 总被引:1,自引:0,他引:1
Weishaupt D Rühm SG Binkert CA Schmidt M Patak MA Steybe F McGill S Debatin JF 《AJR. American journal of roentgenology》2000,175(1):189-195
OBJECTIVE: The purpose of this study was to determine the diagnostic usefulness of a new blood pool contrast agent, NC100150, for assessing the aortoiliac and renal arteries. SUBJECTS AND METHODS: Twenty patients with hemodynamically significant stenosis (> or =50% of luminal diameter) of the iliac or renal arteries or an aortic aneurysm documented by digital subtraction angiography underwent MR angiography at 1.5 T after administration of NC100150. Three-dimensional MR angiographic data sets were collected ill the equilibrium phase. In a prospective analysis, each vascular segment (16 segments per arterial tree) was evaluated. RESULTS: All patients tolerated the NC100150 administration well. Mean contrast-to-noise ratios of the vascular data collected in the equilibrium phase of NC100150 was 3.3+/-15.9. Compared with digital subtraction angiography, the sensitivity and specificity of MR angiography for the renal arteries were 82% and 98%, respectively; for the common iliac arteries, 86% and 97%, respectively; for the external iliac arteries, 80% and 100%, respectively; and for the internal iliac arteries, 71% and 977, respectively. All 83 aneurysmal changes revealed by digital subtraction angiograpy of the aortoiliac arteries were well displayed on the MR angiographic data sets. CONCLUSION: Equilibrium-phase NC 00150-enhanced three-dimensional MR angiography shows high specificity when evaluating the abdominal and pelvic vascular systems, but the attendant venous overlap can limit the assessment of stenosis in renal and pelvic arterial segments. 相似文献
14.
Daniel A. Leung Pia Pelkonen Thomas F. Hany Gesine Zimmermann Thomas Pfammatter Jrg F. Debatin 《Journal of magnetic resonance imaging : JMRI》1998,8(3):598-602
The objective of this study was to evaluate quantitatively and qualitatively the effect of image subtraction on the image quality of three-dimensional (3D) gadolinium-enhanced MR angiograms of the renal arteries. Breath-hold 3D gadolinium MR angiography (MRA) as well as conventional contrast angiography of the renal arteries was performed on 20 patients with suspected renovascular hypertension. MR angiograms were acquired before and during dynamic infusion of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Contrast-enhanced images were compared with images that had undergone voxel-by-voxel signal intensity subtraction of contrast-enhanced data from precontrast data. One false positive finding for significant renal artery stenosis was recorded with MRA using conventional angiography as the gold standard. Image subtraction did not alter the diagnosis at MRA in any case. The mean contrast-to-noise ratio (CNR) was significantly higher (P < .05) on the subtraction MR angiograms compared to the nonsubtracted MR angiograms. There was no significant difference in the signal-to-noise ratio (SNR). Qualitative analysis revealed a significant improvement in image quality after image subtraction with respect to visualization of the distal renal arteries. In conclusion, image subtraction improves the quality of renal MRA in terms of both CNR and visualization of the distal renal arteries. 相似文献
15.
George J. Hunter Leena M. Hamberg Robert M. Weisskoff Elkan F. Halpern Thomas J. Brady 《Journal of magnetic resonance imaging : JMRI》1994,4(1):51-58
The measurement of cardiac output and ejection fraction is useful in the treatment of diverse cardiac and cardiopulmonary disease states. Although several techniques are available for accurate measurement of left ventricular parameters, assessment of the right ventricle is less well represented. No single method is overwhelmingly superior, each having different strengths and weaknesses. In the present study, the applicability of an echo-planar magnetic resonance (MR) imaging method in which a complete volumetric measurement of the right and left ventricles may be obtained during 12 heartbeats is demonstrated. This rapidity permits imaging during a 15-second breath hold. The authors show in 12 volunteers that breath-hold echo-planar volume measurements of both ventricles were consistent with results obtained with conventional MR imaging methods. 相似文献
16.
Ken-Pin Hwang Jordin D Green Debiao Li Orlando P Simonetti Scott A Resnick J Paul Finn Jeffrey L Duerk Reed A Omary 《Journal of magnetic resonance imaging : JMRI》2002,15(1):55-61
PURPOSE: To minimize contrast agent dosage for intra-arterial (IA) contrast-enhanced magnetic resonance angiography (CE-MRA) by examining the effects of encoding order (elliptical vs. sequential) and injection duration (100% to 30% of the acquisition time). MATERIALS AND METHODS: Catheter-based IA gadolinium (Gd) injections were performed in an arterial flow phantom. Blood flow rates, injection rates, and injection durations were systematically varied. Signal-to-noise (SNR) measurements were obtained in the aorta, renal artery, and common iliac artery. RESULTS: No significant SNR losses were observed for any of the vessels with 75% injection duration, or for the aorta and iliac artery with 50% injection duration. Excellent images of all vessels were obtained at 50% injection duration. There was no significant SNR difference between encoding schemes. CONCLUSION: Contrast agent dosage can be substantially reduced without loss of SNR by limiting injection to part of the imaging acquisition time. 相似文献
17.
Comparison of digital subtraction angiography with gadolinium-enhanced magnetic resonance angiography in the diagnosis of renal artery stenosis 总被引:2,自引:0,他引:2
J. Thornton J. O'Callaghan J. Walshe E. O'Brien J. C. Varghese M. J. Lee 《European radiology》1999,9(5):930-934
Renal artery stenosis (RAS) is a treatable cause of hypertension and renal failure for which no ideal screening technique
is currently available. We evaluated the use of dynamic gadolinium-enhanced magnetic resonance angiography (MRA) for the diagnosis
of RAS. Sixty-two patients with secondary hypertension were enrolled in the study. All patients had conventional renal angiography
and gadolinium enhanced MRA. The sequence used was a 3D FMP SPGR sequence with the following parameters (TR: 26 ms, TE: 6.9
ms, flip angle 40 °, field of view 36 × 36 cm, matrix 246 × 256, 1 excitation). Gadolinium 0.3 mmol/kg was administered and
60 1.5-mm-thick partitions were obtained over a duration of 3.5 min. The MRA images were then compared with conventional digital
subtraction angiography (DSA) images. Conventional DSA demonstrated 138 renal arteries, whereas gadolinium-enhanced MRA demonstrated
129 (93 %). Twenty-one renal artery stenoses and four occluded arteries were seen at conventional DSA. Gadolinium-enhanced
MRA had a sensitivity of 88 %, specificity of 98 %, accuracy of 96 %, positive predictive value of 92 % and negative predictive
value of 97 % when compared with conventional DSA. Gadolinium-enhanced MRA is an accurate technique for identifying patients
with RAS. It is less sensitive in picking up accessory renal arteries.
Received: 17 March 1998; Revision received: 30 June 1998; Accepted: 28 August 1998 相似文献
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Transesophageal echocardiography (TEE) is the procedure of choice for identifying aortic atheromas, which may result in stroke, transient ischemic attack and peripheral embolization. However, because of anatomic constraints, the innominate artery may not be visualized. We investigated gadolinium-enhanced MR angiography (MRA) as an alternative technique for evaluation of suspected atheromas of the innominate artery. From a retrospective review of 520 examinations, we identified five patients who had innominate artery atheromas diagnosed prospectively with gadolinium-enhanced MRA who also underwent TEE within 1 month. A total of 10 innominate artery atheromas were demonstrated on MRA; none of these were visualized on TEE. One patient had three atheromas, two patients had two atheromas and three patients had one atheroma. They ranged in size from 3 mm to 1.5 cm (mean 6.5 mm). One atheroma was flat, two were filiform, and seven were protruding. Gadolinium-enhanced MRA is superior to TEE for the diagnosis of atheromas of the innominate artery. In the setting of right cerebral or right arm embolization, when no source is seen in the arch on TEE, gadolinium-enhanced MRA should be considered. 相似文献