共查询到20条相似文献,搜索用时 15 毫秒
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目的对奥曲肽(Octreotide)治疗晚期血吸虫病食管、胃静脉曲张大出血的疗效作出评价。方法将96例病人分为3组,A组32例,用垂体后叶素0.2u/min静脉持续注射,24h后减半剂量连续用3d。B组34例,垂体后叶素的用法同A组,同时加用硝酸甘油10~40μg/min持续静脉注射4d。C组30例,用奥曲肽100μg静脉注射后,以25μg/h的速度持续静脉注射,24h后减半剂量维持1d。结果3组止血率,分别为56.2%(18/32)、50.0%(17/34)及86.7%(26/30),C组明显优于A组与B组(P<0.05)。3组止血有效的病例停药后1周内的再出血率,分别为2/18、2/17及5/26,无显著差异(P>0.05)。结论奥曲肽的疗效明显优于垂体后叶素及硝酸甘油。 相似文献
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目的 评价内镜套钆治疗肝硬化门脉高压食管静脉曲张出血的远期效果。方法 内镜低位密集套扎,首次套扎6-12点,后隔2周重复套扎直至食管静脉曲张完全闭塞和缩小至I度以下。追踪时间,第1次于治后3个月,第2交于治后6-12个月,以后每年1次。追踪发现复发者动员再次套扎。结果 21例中套扎1次3例,2次10例,3次8例。近期止血效果好。随访1-3年,再出血8例,死于再出血4例。死亡病例中肝功能按Child's分级属C级为主。结论 套扎治疗食管静脉曲张出血远期疗效,以反复多次套扎使食管静脉曲张呈根治状态的病例效果好,出血复发率亦低。远期存活率与肝功能损害程度有关。 相似文献
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Large colonic polyps have large vessels, which often cause post‐polypectomy hemorrhage. Some of the stalks of large pedunculated polyps are formed by the weight of the polyps and disappear after polypectomy. There are some reports suggesting that pre‐ligation with EndoloopR may minimize the risk of post‐polypectomy hemorrhage. However, the current density increases more at the site of pre‐ligation as compared with that at the site of polypectomy, because polypectomy is carried out with gradual snaring. This implies that burn injury may also occur at the site of pre‐ligation, causing the loss of pre‐ligation and, consequently, post‐polypectomy hemorrhage. Ligation of stalks after polypectomy is very difficult. The EndoloopR rolls back when it is tightened, because of the lack of torsional stiffness. We have developed a simple and improved post‐polypectomy ligation technique using the Anchor clip. Before polypectomy, an EndoclipR is placed partially at the base of the pedunculated polyp. When the stalk is tightened completely with the EndoclipR before polypectomy, burn injury occurs around the EndoclipR. The Anchor clip at the base of the pedunculated polyp holds the stalk after polypectomy and the constricted part formed by the Anchor clip prevents the rolling up of the EndoloopR and helps in easy ligation of the stalk. We have used the Anchor clip for 50 patients. Application of the EndoloopR after polypectomy was impossible in two patients. The remaining 48 patients underwent EndoloopR–assisted polypectomy with the Anchor clip, and in none of the cases did bleeding occur after polypectomy. 相似文献
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施他宁对食管胃底静脉曲张破裂出血的疗效 总被引:1,自引:0,他引:1
目的 探讨施他宁对食管胃底静脉曲张破裂出血(EVB)的疗效。方法 142例EVB患者随机分为两组:施他宁(SS)组72例,先以250μg静注,随后以250μg·h~(-1)持续静滴共3d;对照组70例,用垂体后叶素20单位加入5%葡萄糖,以0.2u·min~(-1)静滴,1次/8h,共3d。结果 SS组3d天内的止血率明显优于对照组(P<0.01),再出血率(P<0.05)、病死率(P<0.01)及副作用发生率(P<0.01)明显低于对照组。结论 SS是治疗EVB的安全有效药物。 相似文献
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目的 观察巴曲酶联合加压素治疗食管曲张静脉破裂出血的止血效果。方法 70例肝硬化食管曲张静脉出血病人(男62例,女8例,平均年龄46±9岁),随机分成2组,治疗组36例用巴曲酶2kuiv后,随后三天每日静注lku,并给加压素以0.2u/min的速度持续静滴72h。对照组34例,予用加压素1Ou iv后,以相同的速度维持静滴72h。结果 治疗组止血有效率为86.1%(31/36),显著高于对照组(52.9%,18╱34);治疗组病死率19.4%(71/36)明显低于对照组(58.8%,20/34,P相似文献
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目的 探讨抗生素对奥曲肽治疗食管曲张静脉破裂出血(EVB)的影响。方法 60例EVB患者,随机分为2组,分别给予奥曲肽、奥曲肽联合抗生素治疗。结果 EVB患者6小时、12小时、24小时止血率奥曲肽组分别为27%、40%、63%。治疗前后血清一氧化氮(NO)含量分别为6.9±0.82μmol/L、5.6±0.95μmol/L;奥曲肽联合抗生素组止血率分别为50%、70%(P<0.05)、93%(P<0.05)。治疗前后NO含量分别为7.3±0.66μmol/L、4.3±0.79μmol/L(P<0.05)。结论 抗生素能明显提高奥曲肽治疗EVB的疗效,其机理可能与降低血清NO含量有关。 相似文献
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肝硬变上消化道大出血患者62例,出血后6小时~1周内行胃镜检查及硬化剂治疗。检查证实无食管胃底静脉曲张2例;胃及十二指肠球部明显糜烂14例(22.6%),胃和十二指肠球部溃疡6例(9.7%)。9例(14.5%)为非静脉曲张性出血,7例(11.3%)为双因素性出血,表明将肝硬变上消化道大出血一概推断为食管静脉曲张破裂出血是片面的。作者强调早期内镜检查和治疗的重要性。 相似文献
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