半月节脉冲射频治疗三叉神经痛的临床观察

目的 观察螺旋CT引导下半月节穿刺脉冲射频治疗三叉神经痛的临床疗效.方法 100例原发性三叉神经痛患者随机分为研究组(n=44,行半月节脉冲射频治疗)和对照组(n=56,行半月节射频热凝).比较治疗前、治疗后1 d、3 d、1周、1个月,6个月和12个月时的数字评分(NRS)及副作用发生情况.结果 治疗后两组各时间点NRS评分均较治疗前明显降低(P<0.01).对照组见效较快.治疗后随访1年两组疗效相当,研究组的副作用发生率低于对照组.结论 半月节脉冲射频治疗三叉神经痛安全有效、副作用少,适用于高龄、体弱的患者.     

半月节穿刺温控热凝射频术治疗顽固性三叉神经痛358例临床分析

目的：对采用半月节穿刺射频热凝术治疗358例顽固性三又神经痛病人临床资料进行分析，找出影响手术效果的因素及产生并发症的原因。方法：采用侧方入路或前侧入路穿刺半月节进行射频热凝术治疗，效果欠佳者加用眶下孔或颏孔射频治疗，对合并第肢痛的加用眶上孔射频治疗。结果：术后疗效优258例（占72％），良72例（占20％），无效28例（占8％），总有效率为92％。共285例随访3个月～5年。1年内复发16例（5．6％）；2年内复发25例（8．8％）；5年内复发29例（10．2％）。无严重并发症发生。结论：顽固性三又神经痛采用半月节穿刺温控射频治疗的效果满意，加用外周支组合治疗可提高疗效，该方法可进一步推广应用。     

经卵圆孔三叉神经半月节射频热凝术治疗三叉神经痛的效果分析

目的 探讨经卵圆孔三叉神经半月节射频热凝术治疗三叉神经痛的临床效果,分析其并发症的诱发原因与防治措施.方法 选取2018年1月至2021年5月邯郸市眼科医院收治的300例三叉神经痛患者为研究对象,按照随机数字表法分为对照组和观察组,各150例.对照组患者采用常规药物治疗,观察组患者采用经卵圆孔三叉神经半月节射频热凝术治...     

C臂引导下经卵圆孔半月节选择性位点射频治疗三叉神经痛

目的:观察和分析C臂引导下经卵圆孔半月节选择性位点射频治疗三叉神经痛的临床效果。方法:78例三叉神经痛患者依据其受累分支不同分为三组:A组-Ⅱ支,B组-Ⅲ支,C组-Ⅱ、Ⅲ支;通过卵圆孔分区及进针深度确定不同受累分支的治疗位点,进而行C臂引导下射频热凝术。采用视觉模拟评分法(visual analogue scale,VAS)评定术前和术后即刻、3天疼痛程度;术后3月和12月进行疗效随访。结果:各组术后即刻、3天VAS均较术前减低(P<0.05)。术后3月和12月各组有效率均达60%以上,其中单纯Ⅲ支受累者为95.7%,有Ⅱ支受累者相对较低(60%~75.6%)。各例术中及术后均无严重并发症。结论:C臂引导下经卵圆孔半月节选择性位点射频热凝术为治疗第Ⅱ、Ⅲ支三叉神经痛安全而有效的方法。     

三叉神经痛的颅外非半月节射频治疗进展

经皮穿刺三叉神经半月节射频治疗三叉神经痛已有近半个世纪的历史,现已成为三叉神经痛的主要治疗技术之一。但该技术存在对分支选择性不高和颅内穿刺相关的颅内出血与颅内感染风险。本文提出"三叉神经痛颅外非半月节射频治疗"理念,即将三叉神经痛的射频治疗靶点由传统的颅内半月节转移至颅外三叉神经各分支出颅孔洞(眶上孔、圆孔、卵圆孔),从而提高对分支治疗的选择性,避免颅内穿刺相关的颅内出血和感染。并综述了目前在治疗靶点和穿刺路径选择、穿刺影像引导技术、穿刺针具改进、射频参数设定、适应证的选择和治疗过程舒适化等方面的临床应用进展。     

CT引导下半月神经节射频热凝治疗术治疗三叉神经痛的远期疗效分析

三叉神经痛为面部爆发性、短暂性、刺激性、周期性的疼痛,疼痛分布在三叉神经单支或多支分布区,发生率3—5/10万人年,并且随着年龄上升。另有报道,三叉神经痛的国内及国外发病率分别为47.8/10万人口和62.6/10万人口。该病可严重影响患者的生存质量,有研究显示,三叉神经痛患者伴随高发的抑郁和焦虑异常[1]。其治疗方法有:药物治疗、     

CT引导下半月神经节射频热凝治疗三叉神经痛的手术配合

三叉神经痛分为原发性(真性或特发性)和继发性(症状性)两种[1],半月神经节射频热凝治疗三叉神经痛,是目前国际上有效、安全的方法之一[2]。我院2004年1月-2005年1月共开展了此类手术63例。在CT定位引导下行半月神经节穿刺,准确率高,并发症少。术中半月神经节射频热凝毁损,给予无插管异丙酚静脉全麻,患者痛苦小,创伤小,术后愈合快,疗效好。现将手术配合体会介绍如下。1临床资料本组病例63例,男31例,女32例,年龄31~85岁,病程1个月~20年。病变累及三叉神经1支者13例,包括VⅠ支、VⅠVⅡ支、VⅠVⅡVⅢ支,病变累及三叉神经2、3支者50例,包括V…     

CT引导下半月神经节射频热凝治疗三叉神经痛的手术配合

三叉神经痛分为原发性(真性或特发性)和继发性(症状性)两种[1],半月神经节射频热凝治疗三叉神经痛,是目前国际上有效、安全的方法之一[2].我院2004年1月-2005年1月共开展了此类手术63例.在CT定位引导下行半月神经节穿刺,准确率高,并发症少.术中半月神经节射频热凝毁损,给予无插管异丙酚静脉全麻,患者痛苦小,创伤小,术后愈合快,疗效好.现将手术配合体会介绍如下.     

DSA下半月神经节射频热凝术治疗原发性三叉神经痛远期疗效观察

三叉神经痛(trigeminal neuralgia,TN)是指头面部三叉神经分布区内的阵发性剧痛,传统治疗效果不佳且易复发,严重影响患者的生活质量.选择性半月神经节射频热凝术是治疗三叉神经痛的有效方法之一.现将我院从2006年5月至2007年3月收治的199例原发性三叉神经痛患者,均在DSA引导下行半月神经节射频热凝术远期随访的情况报告如下.     

CT引导下三叉神经半月神经节射频热凝术病人的护理

三叉神经痛是口腔科常见疾病之一,疼痛是与存在或潜在组织损伤有关的一种不愉快感觉或情感经历,是一种主观感受,而且一致公认测疼痛＂金标准＂是病人主诉[1]。虽不会危及病人生命,但严重影响病人的生活质量及健康,目前常用治疗方法有药物、针灸等保守治疗,疗效不佳者可行手术治疗,20世纪70年代由Swect等首先采用经皮穿刺半月神经节射频温控热凝术治疗三叉神经痛,其原理是传导痛觉的细纤维70℃～80℃发生变性,而传导触觉粗纤维能耐受更高的温度,采用射频产热并能控制温度的特点来选择部分痛觉纤维。     

脉冲射频治疗三叉神经痛时射频电压与疗效的关系

目的 探讨脉冲射频治疗三叉神经痛时射频电压与术后镇痛效果的关系.方法 选取脉冲射频治疗后效果欠佳的原发三叉神经痛患者22例(无效组)及同期随机选取脉冲射频效果满意的患者22例(有效组),比较两组患者术中射频电压、局部电阻、刺激电压等数据,并且比较两组术后并发症发生情况.结果 有效组射频电压明显高于无效组(P＜0.01),面部麻木患者明显多于无效组(P＜0.01).结论 脉冲射频电压高的患者治疗效果更好.     

3D CT‐Guided Pulsed Radiofrequency Treatment for Trigeminal Neuralgia

Trigeminal neuralgia (TN) is a pain syndrome characterized by pain in the trigeminal area often accompanied by a brief facial spasm or tic. The purpose of our study was to investigate the efficacy and clinical utility of CT‐guided pulsed radiofrequency (PRF) for treatment of TN. Patients who were diagnosed with severe TN between September 2010 and October 2010 at Beijing Tiantan Hospital were included. Pulsed radiofrequency treatment (PRFT) was employed to treat TN. To verify the accurate needle position, a thin‐section cranial CT scan was performed by using a multidetector CT scanner. Three‐dimensional reconstruction was performed to visualize the location of the needle and the foramen ovale. A total of 20 patients were included in the study. Seven patients (35%) had favorable outcome 1 year after the PRFT. The numeric rating scale in the 7 patients with good outcome was significantly lower than the 13 patients with bad outcome at 1 day, 1 week, and 2 weeks after the treatment. The remaining 13 patients had residual pain 2 weeks after the PRFT and had to receive radiofrequency thermocoagulation (RFTC). In conclusion, the results of our study demonstrate that CT‐guided PRFT is not an effective method of pain treatment for idiopathic TN as compared with conventional RFTC. However, CT‐guided PRFT is associated with less complication than RFTC.     

Comparison of High‐voltage‐ with Standard‐voltage Pulsed Radiofrequency of Gasserian Ganglion in the Treatment of Idiopathic Trigeminal Neuralgia

Although pulsed radiofrequency treatment (PRFT) has been used to treat trigeminal neuralgia (TN) safely, satisfactory improvement is lacking. Recently, much attention has been paid to the PRFT dose and intra‐operative parameters. It has been reported that high‐voltage PRFT could significantly reduce discogenic pain. However, there is no study investigating the effects of high‐voltage PRFT on TN. The aim of this prospective, randomized, double‐blinded study was to evaluate the efficacy and safety of high‐voltage PRFT in comparison with standard‐voltage PRFT for idiopathic TN. Sixty severe TN patients were randomly assigned to 2 groups treated with CT‐guided standard‐ or high‐voltage‐pulsed radiofrequency (RF) of Gasserian ganglion, respectively, between January 2012 and July 2012. Numeric Rating Scales (NRS), carbamazepine dose, and side effects were evaluated at day 1, weeks 1 and 2, months 1, 3, and 6, and 1 year postoperative. There were 27 patients in the standard‐voltage group and 26 patients in the high‐voltage group who completed the 1‐year follow‐up study. The effective rates in the standard‐voltage and high‐voltage PRFT groups were 41% and 69%, respectively, at 1, 3, and 6 months postoperative (P = 0.037). The effective rate in the standard‐voltage group decreased to 19% at 1‐year postoperative, while in the high‐voltage group remained at 69% (P = 0.000). No significant side effects were detected in both groups. In conclusion, CT‐guided high‐voltage PRFT is an effective and safe interventional therapeutic choice for idiopathic TN patients.     

Pulsed Radiofrequency V2 Treatment and Intranasal Sphenopalatine Ganglion Block: A Combination Therapy for Atypical Trigeminal Neuralgia

Trigeminal neuralgia (TN) is a chronic condition affecting the fifth cranial nerve and resulting in sporadic intense burning and shock‐like pain lasting for seconds to minutes that can be incapacitating to patients. Atypical TN includes additional features such as continuous pain and sensory disturbances in the area innervated by one or more branches of the trigeminal nerve. Documented cases of TN have dated back to the 18th century. Today, there are roughly 140,000 people suffering with this condition in the U.S.A. Conventional treatments for this disorder include medical management with nonconvulsants such as carbamazepine, which decrease the nerves response to peripheral stimulation. These agents have good initial pain relief, but relief rates fall off dramatically over the long‐term. Recently, methadone has shown promise as a pharmacologic adjunct to patients with intractable neuropathic noncancer pain, including patients suffering from TN. Cases refractory to medical management can be treated with surgical microdecompression or minimally invasive procedures such as radiofrequency (RF) treatment. Pulsed RF (PRF) is a method gaining interest as it is delivered in pulses, allowing adequate time for dissipation of heat and energy resulting in less damage to surrounding structures. This case report describes the successful treatment of atypical V2 TN refractive to medical management requiring PRF treatment, a sphenopalatine block series, and low‐dose methadone.     

Intracranial Hemorrhage After Percutaneous Radiofrequency Trigeminal Rhizotomy

Radiofrequency thermocoagulation (RFT) of trigeminal ganglion is a commonly performed percutaneous procedure for the management of trigeminal neuralgia. However, it is not free from potentially life-threatening complications. A case of intracranial hemorrhage following RFT, which was managed conservatively, is reported. The authors suggest that coagulation parameters be normalized and intra-procedural blood pressure controlled while performing this technique. As RFT is carried out as an ambulatory procedure, absence of any intracranial complication must be ascertained clinically before the patient is discharged.     

半月神经节联合射频治疗三叉神经痛的临床研究

目的:观察CT引导下半月神经节脉冲射频联合连续射频治疗三叉神经痛的临床效果。方法:90例原发性三叉神经痛患者随机分为对照组(CRF组,单纯采用75℃连续射频进行治疗,N=45)和联合射频组(采用42℃脉冲射频和75℃连续射频进行治疗,CRF+PRF组,N=45),比较治疗前、治疗后1d、3d、7d、3个月、6个月、1年、2年的视觉模拟评分(VAS)、疼痛缓解率,以及治疗前、治疗后3个月、6个月、1年、2年的生存质量评分(QOL)、麻木评分和并发症发生率。结果:治疗后两组患者的VAS评分均较治疗前明显降低(P<0.05),随访2年两种方法治疗的有效率均达100%(P>0.05);治疗后7d联合射频组的VAS显著低于CRF组(P<0.05),但治疗后2年联合射频组的VAS评分较对照组明显增高(P<0.05);治疗后2年联合射频组的麻木发生率和麻木评分均较对照组明显降低(P<0.05)。结论:半月神经节脉冲射频联合连续射频可有效缓解三叉神经痛,尽管短期疗效超过了连续射频,但长期疗效低于连续射频,并发症的发生率明显低于连续射频。     

Radiofrequency and Pulsed Radiofrequency Treatment of Chronic Pain Syndromes: The Available Evidence

There are currently 6 reviews on (pulsed) radiofrequency (RF) for the management of spinal pain. Two reviews on interventional pain management techniques in general also discuss RF. The outcomes of those reviews depend on the type of studies included and the opinion of the reviewers, which may result in different evidence levels. Radiofrequency denervation at the cervical and lumbar level has produced the most solid evidence. The differences in treatment outcome registered in the 5 randomized controlled trials (RCTs) regarding lumbar facet denervation can be attributed to differences in patient selection and/or inappropriate technique. There is not sufficient evidence supporting the use of RF facet denervation for the management of cervicogenic headache. The studies examining the management of cervical radicular pain suggest a comparable efficacy for RF and pulsed RF (PRF). The PRF treatment is supposed to be safer and therefore should be preferred. The superiority of RF treatment adjacent to the lumbar dorsal root ganglion for the management of lumbar radicular pain has not been demonstrated in an RCT. Information regarding RF treatment of sacroiliac joint pain is accumulating. No randomized sham‐controlled trials on the value of RF treatment of the Gasserian ganglion for the management of idiopathic trigeminal neuralgia have been published. One RCT indicates superiority of RF over PRF for the management of idiopathic trigeminal neuralgia. Future research to confirm or deny the efficacy of (P)RF should be conducted in carefully selected patient populations. The tests used for patient inclusion in such a trial could potentially help the clinician in selecting patients for this type of treatment. The value of PRF treatment of the peripheral nerves also needs to be confirmed in well‐designed trials.