半月神经节高电压脉冲射频治疗原发性三叉神经痛的疗效

目的:探讨半月神经节高电压脉冲射频治疗原发性三叉神经痛的疗效及安全性。方法:60例保守治疗无效的原发性三叉神经痛患者随机分为两组,分别接受半月神经节标准电压和高电压脉冲射频治疗,比较两组的疗效及副作用。结果:术后6月有效率标准电压组(41%)明显低于高电压组(69%)(P=0.037);术后1年有效率标准电压组降至19%,显著低于高电压组(69%)(P=0.000)。两组脉冲射频治疗后均未发现明显副作用。结论:高电压脉冲射频治疗三叉神经痛患者安全有效,这种非毁损的技术将为三叉神经痛患者提供又一治疗选择。     

影响脉冲射频治疗原发三叉神经痛患者疗效的因素

目的:分析影响脉冲射频治疗原发三叉神经痛患者疗效的因素。方法:CT引导下半月神经节脉冲射频治疗28例原发三叉神经痛患者,以治疗后2周疼痛程度降低50%以上为标准将患者分为有效组和效差组,比较两组患者术前、术中和术后的临床资料。结果:11例患者有效,17例患者效差改行射频热凝术治疗。两组患者年龄、性别、病程、术前疼痛程度、术前抗癫痫类药物用量、术中电刺激定位时电压、电阻、手术时间均无显著性差异,但有效组疼痛治疗发生器上监测的电压、计算的电场强度均明显高于效差组(P<0.05)。患者术后2周NRS评分与术中输出电压和电场强度呈明显的负相关(P<0.05)。结论:高电场效应治疗三叉神经痛的效果更好,提示提高术中电压即电场强度可能是提高疗效的方法之一。     

螺旋CT引导半月节脉冲射频治疗三又神经痛的远期疗效观察

目的 观察螺旋CT引导下半月节穿刺脉冲射频治疗三叉神经痛的远期疗效.方法 100例原发性三叉神经痛患者分为研究组(脉冲射频组,n=44)和对照组(射频热凝组,n=56).比较治疗前,治疗后0.5年、1年、2年时的疼痛数字模拟评分(NRS)及临床疗效.结果 治疗后1年内两组NRS无显著性差异,但2年后研究组复发率明显高于对照组(P＜0.01).结论 半月节脉冲射频治疗三叉神经痛安全有效,但远期疗效欠佳.     

50℃脉冲射频治疗三叉神经痛患者的临床效果

目的:探讨50℃脉冲射频治疗三叉神经痛患者的疗效及安全性。方法:对我院42℃标准脉冲射频治疗后效果欠佳的原发三叉神经痛患者32例行50℃脉冲射频治疗,评价治疗前后的疼痛程度数字评分(numerical rating scale,NRS),记录并发症发生情况。结果:42℃标准脉冲射频治疗后效果欠佳改行50℃脉冲射频治疗后NRS较治疗前明显降低(P<0.01),治疗后面部有轻度麻木感,但短期内(平均2.1月)即可完全恢复,无其他严重并发症发生。结论:50℃脉冲射频治疗三叉神经痛安全、有效,是42℃标准脉冲射频无效时的临床选择。     

脉冲射频配合针灸牵引治疗神经根型颈椎病的临床研究

目的 观察脉冲射频配合针灸、牵引对神经根型颈椎病的治疗效果.方法 62例神经根型颈椎病患者分为治疗组(脉冲射频配合针灸、牵引治疗)和对照组(单纯针灸、牵引治疗),每组31例.比较两组临床疗效.结果 治疗组有效率及治愈率明显高于对照组(P＜0.01),无严重不良反应发生.结论 脉冲射频配合针灸、牵引治疗神经根型颈椎病的疗效优于单纯针灸、牵引治疗.     

探讨半月神经节不同温度模式射频在老年三叉神经痛中的治疗效果

目的探讨半月神经节不同温度模式射频在老年三叉神经痛(TN)中的治疗效果。方法选取我院2015年4月~2016年7月收治的TN患者80例,随机数字表法分为观察组和对照组各40例。对照组采用75℃+脉冲射频治疗,观察组采用70℃+脉冲射频治疗。对比两组手术前后面部疼痛、麻木评分、生活质量评分及临床疗效。结果两组术前面部疼痛、麻木评分、生活质量评分比较,差异无统计学意义(P0.05),术后3个月观察组面部疼痛、麻木评分低于对照组,生活质量评分高于对照组,差异有统计学意义(P0.05)。观察组治疗总有效率92.50%低于对照组70.00%,差异有统计学意义(P0.05)。方法半月神经节不同温度模式射频可有效治疗老年TN,其中70℃+脉冲射频效果显著,可有效改善患者面部疼痛、麻木症状,减轻患者痛苦,提高生活质量。     

半月节脉冲射频治疗三叉神经痛的临床观察

目的 观察螺旋CT引导下半月节穿刺脉冲射频治疗三叉神经痛的临床疗效.方法 100例原发性三叉神经痛患者随机分为研究组(n=44,行半月节脉冲射频治疗)和对照组(n=56,行半月节射频热凝).比较治疗前、治疗后1 d、3 d、1周、1个月,6个月和12个月时的数字评分(NRS)及副作用发生情况.结果 治疗后两组各时间点NRS评分均较治疗前明显降低(P<0.01).对照组见效较快.治疗后随访1年两组疗效相当,研究组的副作用发生率低于对照组.结论 半月节脉冲射频治疗三叉神经痛安全有效、副作用少,适用于高龄、体弱的患者.     

DSA引导下射频热凝术治疗三叉神经痛精细化护理干预效果

目的:探讨精细化护理在DSA引导下射频热凝术治疗三叉神经痛中干预的效果研究。方法:采用随机对照研究,选取射频治疗术治疗三叉神经痛患者60例,利用随机号码表抽取样本的方法将60例患者分为两组,对照组30例,观察组30例。对对照组施行常规护理方案,对观察组施行精细化护理方案。观察两组患者的疗效、VAS评分、生活质量评分、术后感染率、复发率及患者满意度。结果:两组治疗效果的对比有显著性差异(P0.05);观察组病人的疼痛VAS评分低于对照组、生活质量评分高于对照组(P0.05);观察组术后感染率、复发率低于对照组(P0.05);对照组对护理工作的满意率为56.67%,两组满意率的对比有明显差异(P0.05)。结论:精细化护理在DSA射频治疗术治疗三叉神经痛围手术期能够提高手术疗效,缓解病人疼痛,并能有效降低手术风险,减少手术并发症的发生,提高患者生活质量,增加患者满意度。     

腰椎多靶点射频联合银质针疗法对老年腰椎椎管狭窄症的临床疗效

目的 分析腰椎多靶点射频联合银质针疗法治疗老年退行性腰椎椎管狭窄症的临床效果.方法 选取48例老年腰椎椎管狭窄症患者,按照治疗方法的不同分为射频组22例和联合组26例.比较2组患者术后1、3、6、12个月视觉模拟评分法(VAS)评分和临床治疗有效率.记录2组不良反应和并发症发生情况.结果 2组术后1、3、6、12个月VAS评分均低于术前,且联合组VAS评分低于射频组,差异有统计学意义(P＜0.05或P＜0.01).术后1、3、6、12个月,联合组临床治疗有效率高于射频组,差异有统计学意义(P＜0.01).2组均无不良反应和并发症发生.结论 腰椎多靶点射频联合银质针治疗老年腰椎椎管狭窄症的近期及中期疗效较好,且风险低.     

半月神经节射频损毁术治疗三叉神经痛的护理

目的 探讨对经射频热凝术治疗的三叉神经痛患者做好围手术期护理对治疗效果的影响.方法 180例经保守治疗无效的三叉神经痛患者采用经皮射频热凝术治疗,随机分为两组,护理组实施心理护理、术中的严密配合、观察术后反应及采取相应的护理措施.结果 护理组治愈率98％,对照组治愈率80％,无死亡、无永久并发症发生.结论 积极有效的护理干预措施对提高经皮射频热凝术治疗三叉神经痛的疗效,降低不良反应具有重要作用.     

射频热凝联合阿霉素治疗原发性三叉神经痛

目的:探讨射频热凝联合阿霉素治疗原发性三叉神经痛的安全性及临床疗效.方法150例三叉神经痛患者随机分成两组,RFT组(n=75):行单纯射频热凝术;RFT+A组(n=75):同RFT组方法行射频热凝后注射阿霉素3毫克.观察两种方法的疗效、复发率及副反应.结果:两种方法治疗三叉神经痛均获得良好的近期效果,RFT+A组副反应多于RFT组,RFT+A组远期复发率低于RFT组.结论:射频热凝联合阿霉素治疗原发性三叉神经痛远期效果优于单纯射频热凝术.阿霉素可暂时引起头痛、恶心、呕吐等不适.     

Pulsed radiofrequency treatment of the Gasserian ganglion in patients with idiopathic trigeminal neuralgia

Pulsed radiofrequency treatment has been described as a minimal invasive alternative to radiofrequency thermocoagulation for the management of chronic pain syndromes. We present here our first five high-risk patients with idiopathic trigeminal neuralgia who were treated with pulsed radiofrequency after multidisciplinary assessment; with a mean follow-up of 19.2 months (range 10-26). These patients were at high risk due to age, co-morbidities or previous interventional and surgical treatments. An excellent long-term effect was achieved in three of the five patients, a partial effect in one patient and a short-term effect in one patient. No neurological side effects or complications were reported.     

Pulsed radiofrequency treatment for idiopathic trigeminal neuralgia: A retrospective analysis of the causes for ineffective pain relief

We retrospectively analyzed the reasons for ineffective pain relief in patients with idiopathic trigeminal neuralgia (TN) who had undergone pulsed radiofrequency (PRF) treatment guided by computed tomography scan. We found that intraoperative PRF output voltage and electrical field intensity was significantly higher (p < 0.05) in the group who had received effective treatment than in the ineffective group. These findings suggest that optimizing PRF parameters and increasing the intraoperative output voltage (electric field intensity) may therefore, provide better pain relief in patients with TN.     

Comparison of pulsed radiofrequency with conventional radiofrequency in the treatment of idiopathic trigeminal neuralgia.

The aim of this prospective, randomized, double-blinded study was to evaluate the effect of pulsed radiofrequency (PRF) in comparison with conventional radiofrequency (CRF) in the treatment of idiopathic trigeminal neuralgia. A total of 40 patients with idiopathic trigeminal neuralgia were included. The 20 patients in each group were randomly assigned to one of the two treatment groups. Each patient in the Group 1 was treated with CRF, whereas each patient in the Group 2 was treated by PRF. Evaluation parameters were: pain intensity using a Visual Analogue Scale (VAS), patient satisfaction using a Patient Satisfaction Scale (PSS), additional pharmacological treatment, side effects, and complications related to the technique. The VAS scores decreased significantly (p<0.001) and PSS improved significantly after the procedure in Group 1. The VAS score decreased in only 2 of 20 patients from the PRF group (Group 2) and pain recurrence occurred 3 months after the procedure. At the end of 3 months, we decided to perform CRF in Group 2, because all patients in this group still had intractable pain. After the CRF treatment, the median VAS score decreased (p<0.001) and PSS improved (p<0.001) significantly. In conclusion, the results of our study demonstrate that unlike CRF, PRF is not an effective method of pain treatment for idiopathic trigeminal neuralgia.     

选择性射频热凝治疗三叉神经痛1936例临床分析与手术技巧

目的：总结1936例选择性射频热凝治疗的三叉神经痛病例的经验和体会，探讨三叉神经痛射频热凝治疗的方法和技巧。方法：分别进行眶上孔入路、眶下孔入路、侧入路或前入路卵圆孔射频热凝治疗。对Hartel前入路卵圆孔穿刺法进行改良。对45例半月神经节定位困难的三叉神经痛病人，在射频热凝治疗术中应用X线、三维CT或导航进行卵圆孔定位或在术中验证靶点。结果：术后即刻疗效，优良1528例，良好336例，无疗效72例，总有效率96．3％。8个月～2年远期随访1097例，1年内复发122例，复发率为11．1％，2年内复发274例，复发率为24．9％，无严重并发症。结论：温控射频热凝治疗三叉神经痛疗效可靠，X线、三维CT及导航卵圆孔定位在一定程度上弥补了徒手穿刺的缺陷。     

Comparison of High‐voltage‐ with Standard‐voltage Pulsed Radiofrequency of Gasserian Ganglion in the Treatment of Idiopathic Trigeminal Neuralgia

Although pulsed radiofrequency treatment (PRFT) has been used to treat trigeminal neuralgia (TN) safely, satisfactory improvement is lacking. Recently, much attention has been paid to the PRFT dose and intra‐operative parameters. It has been reported that high‐voltage PRFT could significantly reduce discogenic pain. However, there is no study investigating the effects of high‐voltage PRFT on TN. The aim of this prospective, randomized, double‐blinded study was to evaluate the efficacy and safety of high‐voltage PRFT in comparison with standard‐voltage PRFT for idiopathic TN. Sixty severe TN patients were randomly assigned to 2 groups treated with CT‐guided standard‐ or high‐voltage‐pulsed radiofrequency (RF) of Gasserian ganglion, respectively, between January 2012 and July 2012. Numeric Rating Scales (NRS), carbamazepine dose, and side effects were evaluated at day 1, weeks 1 and 2, months 1, 3, and 6, and 1 year postoperative. There were 27 patients in the standard‐voltage group and 26 patients in the high‐voltage group who completed the 1‐year follow‐up study. The effective rates in the standard‐voltage and high‐voltage PRFT groups were 41% and 69%, respectively, at 1, 3, and 6 months postoperative (P = 0.037). The effective rate in the standard‐voltage group decreased to 19% at 1‐year postoperative, while in the high‐voltage group remained at 69% (P = 0.000). No significant side effects were detected in both groups. In conclusion, CT‐guided high‐voltage PRFT is an effective and safe interventional therapeutic choice for idiopathic TN patients.     

脉冲射频刺激联合普瑞巴林治疗带状疱疹后遗三叉神经痛的临床效果

目的 探讨脉冲射频刺激联合普瑞巴林治疗带状疱疹后遗三叉神经痛的临床效果,为临床治疗该病提供参考依据.方法 选取我科室于2017年2月至2020年2月收治的358例带状疱疹后遗三叉神经疼痛者为研究对象,以随机数字表法将其分为对照组和观察组,各179例.对照组给予普瑞巴林治疗,观察组给予脉冲射频刺激联合普瑞巴林治疗.比较两...     

半月节穿刺温控热凝射频术治疗顽固性三叉神经痛358例临床分析

目的：对采用半月节穿刺射频热凝术治疗358例顽固性三又神经痛病人临床资料进行分析，找出影响手术效果的因素及产生并发症的原因。方法：采用侧方入路或前侧入路穿刺半月节进行射频热凝术治疗，效果欠佳者加用眶下孔或颏孔射频治疗，对合并第肢痛的加用眶上孔射频治疗。结果：术后疗效优258例（占72％），良72例（占20％），无效28例（占8％），总有效率为92％。共285例随访3个月～5年。1年内复发16例（5．6％）；2年内复发25例（8．8％）；5年内复发29例（10．2％）。无严重并发症发生。结论：顽固性三又神经痛采用半月节穿刺温控射频治疗的效果满意，加用外周支组合治疗可提高疗效，该方法可进一步推广应用。     

McGill疼痛问卷在三叉神经痛诊断和治疗中的应用

目的:通过采用McGill疼痛问卷(McGill pain questionnaire,MPQ)鉴别三叉神经痛,并观察射频热凝术的疗效,研究MPQ在面痛诊断上的重要性。方法:本研究共观察159例三叉神经痛患者,其中136例患有典型三叉神经痛(CTN),23例患有混合型三叉神经痛(MTN)。采用MPQ评估患者的疼痛,并观察其中124例术后患者疼痛的缓解情况。结果:CTN组的平均现有疼痛强度(PPI)值为4.20±0.34,MTN组的平均PPI值为3.50±0.57,明显低于CTN组(P0.001);与MTN患者相比,CTN患者在疼痛分级指数(PRI)-感觉项上报告了更高的强度(P0.001);两组间PRI-情感和PRI-评价项上有明显区别,CTN组的得分更高(P0.001);RFT术后CTN患者显示了高的立即疼痛缓解率,达到93.6%。MTN患者的结果没有CTN组的好,只有58.8%的患者疼痛明显缓解。结论:MPQ可以很好鉴别不同类型的三叉神经痛,鉴于射频热凝治疗两种三叉神经痛疗效的差异,使用MPQ在面痛诊断中有重要意义。