合格伦综合征磁共振涎腺造影图像分析

目的：分析舍格伦综合征患者的腮腺磁共振涎腺造影表现、特点及应用价值。方法：应用1．5T超导型全身磁共振扫描仪对32例舍格伦综合征患者进行磁共振涎腺造影检查，获得自旋回波磁共振涎腺造影，对其特点进行观察和总结。结果：在舍格伦综合征患者磁共振成像中可看到点状、球状、腔状及破坏性表现，少数有正常的主导管和分支导管表现；无造影检查所见主导管层状或葱皮状。结论：磁共振涎腺造影可客观、清晰地反映舍格伦综合征患者腮腺主分支导管、腺泡病变，可作为诊断舍格伦综合征的依据之一。     

合格伦综合征磁共振涎腺造影图像分析

目的:分析舍格伦综合征患者的腮腺磁共振涎腺造影表现、特点及应用价值.方法:应用1.5T超导型全身磁共振扫描仪对32例舍格伦综合征患者进行磁共振涎腺造影检查.获得自旋回波磁共振涎腺造影,对其特点进行观察和总结.结果:在舍格伦综合征患者磁共振成像中可看到点状、球状、腔状及破坏性表现,少数有正常的主导管和分支导管表现;无造影检查所见主导管层状或葱皮状.结论:磁共振涎腺造影可客观、清晰地反映舍格伦综合征患者腮腺主分支导管、腺泡病变,可作为诊断舍格伦综合征的依据之一.     

磁共振腮腺导管成像术对慢性阻塞性腮腺炎的诊断价值

目的 评价磁共振腮腺导管成像术(MRS)对慢性阻塞性嘿腺炎（COP）的诊断价值：方法：18例患者在经X线腮腺造影检查，确诊为慢性阻塞性腮腺炎后，再行磁共振检查。磁共振检查采用重T2加权序列TR=4000ms．TE=250ms)及快速自旋回波水成像技术并做最大信号强度投影(MIP)处理，获得腮腺导管的成像图像(MRS)，比较X线腮腺造影和MRS对慢性阻塞性腮腺炎的诊断准确率。结果：MRS可显示哩腺的主导管和一级分支导管．对COP的定性诊断准确率为94．4％(17/18)，定位诊断准确率达100%(17/17)。结论：MRS可成功地用于腮腺的导管系统检查，具有无创性特点，在慢性阻塞性腮腺炎的诊断中，有望取代部分创伤性憾腺造影检查。     

腮腺炎性肿块的临床,造影及病理分析

本文报道３２例腮腺性肿块临床，造影及病理分析，术前诊断：良性肿物１５例，肿物性质待查５例，舍格伦综合征结节型９例，腮腺炎性包块３例，本次根据病理并结合临床及造影重新诊断：１８例慢性炎症，１４例舍格伦综合征结节型，在临床上，３２例患者中１６例表现为无任何不适感的腮腺区肿块，９例伴有腮腺肿块史，７例有口干，眼干或疼痛症状。在腮腺造影上，２７例腮腺造影患者中６例全导管扩张，９例末梢导管扩张，１７例腺泡充     

腮腺造影用于腮腺疾病的诊断112例分析

目的探讨腮腺造影对腮腺疾病的诊断价值。方法回顾性分析112例139个腺体的腮腺造影影像学特征及诊断结果。结果舍格伦综合征38例、儿童复发性腮腺炎27例、慢性阻塞性腮腺炎29例,其影像学表现符合其各自的特征性表现而得到确诊,良性肥大8例中的2例结合B超检查确诊,腮腺肿瘤10例中有2例结合B超检查定性。结论腮腺造影对腮腺非肿瘤性疾病有诊断价值,腮腺肿瘤应结合病史、化验并配合高频超声等其他手段提高诊断准确率。     

腮腺舍格伦综合征与非霍奇金淋巴瘤相关性分析

目的:了解腮腺非霍奇金淋巴瘤与舍格伦综合征的临床及发病机制的相关性，正确诊断和治疗舍格伦综合征，尽早明确有无恶性变。方法：对142例口腔颌面部的非霍奇金淋巴瘤中21例发生在腮腺的非霍奇金淋巴瘤，及3例从合格伦综合征演变成淋巴瘤的病例进行分析。结果：21例腮腺区非霍奇金淋巴瘤的局部表现主要为肿块、反复肿胀，与类肿瘤型舍格伦综合征的一般特征和腮腺表现有相关性，其中3例腮腺淋巴瘤患者有明确的舍格伦综合征病史。结论：舍格伦综合征与腮腺非霍奇金淋巴瘤的发生发展，以及临床表现有相关性，部分类肿瘤型舍格伦综合征可演变为淋巴瘤，临床表现和免疫学改变可早期判断舍格伦综合征有无恶性变。     

~(99m)锝腮腺动态显像对舍格伦综合征的诊断价值

目的 探讨＾９９ｍ锝腮腺动态显像对诊断舍格伦征的价值。方法 应用＾９９ｍ锝对临床诊断为舍格伦综合征的５２例患者进行腮腺动态显像,将所得的结果应用计算机ＲＯＩ程序进行定量分析和动态曲线分析,结果 腮腺外形较正常大者４６例（８８．４％）肿大腮腺轮廓清晰２８例（５３．８５％）轮廓模糊１８例（３４．６２％）腮腺功能正常７例（１３．４６％）轻度受损１５例（２８．８４％）中８度受损１７例（３２．６９％）,重度     

85例舍格伦综合征腮腺表现的临床分析与探讨

目的　为了明确舍格伦综合征腮腺表现的特点;以及与其它临床表现之间的关系。方法　对85例舍格伦综合征患者的临床资料进行回顾性分析,并结合文献进一步进行探讨。结果　舍格伦综合征的腮腺表现以炎症型最多;肥大型次之;类肿瘤型最少;三者与口干燥之间的关系存在显著差异;部分患者有恶变可能。结论　舍格伦综合征腮腺表现的特点是该病诊断的一个重要依据,临床应引起重视     

口腔诊断学

磁共振腮腺导管成像术对慢性阻塞性腮腺炎的诊断价值／沈宁…∥上海口腔医学．3种检查方法对早期邻面龋诊断水平的评价／李涢…∥实用口腔医学杂志．舍格伦综合征MRI造影和X线造影的对比研究／郑凌艳…∥中国口腔颌面外科杂志。     

舍格伦综合症55例临床及X线研究

本文报道我院近５年来５５例舍格伦综合征的临床及Ｘ线表现，其中女性４１例，男性１４例，女性占７５％，高发年龄４０岁以上４４例，占８０％。本文就其临床表现及Ｘ线造影进行讨论，同时将影像诊断分为四型。５５例中，５０例初诊为ＳＳ，５例初诊为慢性化脓性炎症。影像诊断与临床诊断之初诊符合率达９０．９％。少数ＳＳ患者早期，特别是腮腺反复肿胀、口眼干燥不明显，易误诊为慢性化脓性腮腺炎，对这种ＳＳ亚临床型，作者认为除临床各种检查外，应做双侧造影检查，并随访观察。当前腮腺造影对舍格伦综合征的诊断仍不失为一有效的方法     

Orofacial granulomatosis: presentation, pathology and management of 13 cases

BACKGROUND: Orofacial granulomatosis (OFG) comprises of a group of conditions, all characterized histologically by the presence of granulomatous inflammation. METHODS: This diagnosis may be determined by exclusion from other conditions that may present with similar clinical and histopathologic features. These include Melkersson-Rosenthal syndrome (MRS), Miescher's cheilitis (an oligosymptomatic form of MRS), Crohn's disease, and sarcoidosis. RESULTS: A great deal of attention has been devoted to the similarity and overlap in clinicopathologic and histomorphologic features of these conditions, suggesting that they may actually represent a spectrum within a single overarching entity. In the review of the 13 cases of OFG retrieved from the files of the Long Island Jewish Medical Center, Department of Dental Medicine, we describe their presentation, clinicopathologic features, and management. These cases comprise examples of MRS (in its oligosymptomatic forms) and Crohn's disease. The similarity, kinship, and overlap between the cases presented are clearly demonstrated. CONCLUSION: In addition, based upon our observations and review, we propose the notion that oral manifestations of Crohn's disease may be classified as an oligosymptomatic form of MRS.     

造影-介入治疗慢性化脓性腮腺炎78例分析

目的 探讨造影—介入方法诊断和治疗慢性化脓性腮腺炎的价值。方法 对78例接受过全身抗感染治疗和支持疗法，但疗效不明显的慢性腮腺炎病人，在X线监控下行48％碘化油注射造影。根据影像所见，将患者分为慢性阻塞性(21例)和慢性非阻塞性(57例)腮腺炎。造影前，经微导管引流腮腺内分泌液，做细菌培养及药敏试验。对慢性阻塞性腮腺炎病人，给予经导管向腮腺内灌注2％利多卡因、1％甲紫治疗。对慢性非阻塞性腮腺炎病人，用同样方法注入α—糜蛋白酶、丁胺卡那霉素、生理盐水混合液治疗。结果 慢性阻塞性腮腺炎组治愈率为80．95％，慢性非阻塞性腮腺炎组治愈率为87．72％。结论 造影—介入是诊断和治疗慢性化脓性腮腺炎确切有效的方法。     

腮腺导管磁共振成像研究

目的　探讨磁共振腮腺导管成像术用于诊断腮腺疾病的可行性 ,并筛选出可获得最佳显示效果的扫描序列。方法　采用 4种不同的扫描序列 ,对 2 3例腮腺疾病患者 (病变组 )及 5名健康志愿者 (对照组 )行磁共振腮腺导管成像。首次扫描后 ,患者含化VitC 2 0 0mg ,于含药后 3、10min再次扫描 ,将所获图像按腮腺导管及其分支显示效果分级 ,比较各扫描序列及服药前后的显示效果。并依据图像对疾病定性诊断 ,将诊断结果与术后病理诊断结果比较。结果　磁共振腮腺导管成像能清楚地显示腮腺主导管、叶间导管、小叶间导管及小叶内导管 ,清楚显示导管有无狭窄、扩张、导管中断及破坏的情况 ,对疾病定性诊断的准确率为 95 6 %。扫描序列中 ,以IR FSE序列的显示效果最佳 ,与FSE比较 ,效果明显提高 (P <0 0 5 )。含服VitC并不显著提高显示效果 (P >0 0 5 )。结论　磁共振腮腺导管成像能清晰显示腮腺导管及其病理改变 ,对腮腺疾病的定性诊断准确率高于普通腮腺造影术。其中IR FSE脂肪抑制序列的显示效果最好 ,可作为腮腺导管X线造影的替代方法应用于临床     

Accuracy in the diagnosis of parotid tumours.

Parotid lesions are often not easily classified. Important information is gathered by conventional and instrumental investigation. But these data are often insufficient to make a correct diagnosis. The authors have compared these techniques. In particular, they have evaluated their accuracy in identification of site and histology. 60 patients with parotid tumours underwent the same instrumental diagnostic techniques (echography, sialography, computed tomography and fine needle aspiration biopsy). In regard to the identification of the site, the highest percentage was achieved by computed tomography (98%). Echotomography has shown an accuracy of 83%, and sialography 87%. Fine needle aspiration biopsy has allowed the definition of the histiotype in 98% of cases. Computed tomography, echotomography and sialography have not allowed the definition of histiotype in malignant tumours, but in the case of benign tumours computed tomography has permitted a diagnosis in 29 cases (57% of benign tumours). Echotomography and sialography in 25 (49%) and 26 cases (51%), respectively.     

Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications

INTRODUCTION: Confirmation of a clinical diagnosis of oral lichen planus (OLP) by means of histopathologic study of a biopsy specimen is generally advised. However, hardly any data exist about the correlation between clinical and histopathologic diagnoses of OLP. The aim of the present investigation was to study the correlation between the clinical and histopathologic assessment of OLP, and to propose diagnostic refinements, if appropriate. METHODS: Clinical and histopathologic data of two previously published studies were used for this purpose. The number of clinical cases in which all clinicians agreed as well as the number of microscopic slides on which all reviewing pathologists agreed were calculated and compared with each other in order to assess the clinicopathologic correlation. RESULTS: In 42% of the cases in which all clinicians agreed about the clinical diagnosis being diagnostic of OLP, there appeared to be no consensus on the histopathologic diagnosis. Conversely, in 50% of the cases in which all pathologists agreed about the histopathologic diagnosis being diagnostic of OLP there was a lack of consensus on the clinical diagnosis. CONCLUSION: Based on the findings of the present study, there appears to be a lack of clinicopathologic correlation in the diagnostic assessment of OLP. We therefore propose a set of revised diagnostic criteria of OLP and oral lichenoid lesions, based on the WHO definition of OLP, including clinical as well as histopathologic aspects.     

涎腺疾病导管系统的磁共振水成像研究

目的应用磁共振水成像术(MRH)衍生的磁共振涎管成像术(MRS)对涎腺病变导管系统变化进行观察。方法对33例涎腺病变患者进行MRS,采用4种序列显示腮腺导管系统,然后给患者含服维生素C,分别于3min和10min后再次扫描,比较腮腺导管系统的显示效果。结果IR-FSE序列较FSE腮腺导管显示效果明显提高(P<0.05),服药后腮腺导管显示效果有一定的提高(P>0.05)。结论MRS对腮腺导管系统显像良好,具有简单、无创、安全等优点,能提供全面、立体的腮腺病变信息。     

慢性复发性腮腺炎的诊断和治疗进展

慢性复发性腮腺炎是一类非阻塞性的腮腺炎性疾病,常表现为腮腺间断性的反复肿胀,可发生在儿童或成人,但以儿童复发性腮腺炎最为常见。这类疾病病因不明确,临床表现与其他疾病类似,目前缺乏有效的防治办法。本文回顾近年来慢性复发性腮腺炎的病因研究进展,阐述并比较了腮腺造影、超声及内镜分别在本病的诊断与治疗过程中的作用,总结儿童及成人复发性腮腺炎的诊断、鉴别诊断的要点,并分析了慢性复发性腮腺炎与临床上较易混淆的舍格伦综合征两类疾病的关系与鉴别方法。