Assessment of the Subclavian Vein in Patients with Transvenous Pacemaker Leads

Thrombosis of the subclavian vein can occur after the implantation of transvenous pacemaker electrodes. Although this is seldom followed by thromboembolic complications, it can cause problems when replacing the leads. To assess the impact of the pacemaker leads on the subclavian vein, a study using nonin-vasive duplex sonography was performed on 56 patients at an average of 41 months after the implantation. Forty-three percent of the patients were found to have a normal function of the subclavian vein, 46% developed pathological changes of the vessel wall, and 11% occluded. These changes rarelv caused symptoms, and, therefore, had little clinical significance. Moreover, the occlusion rate was found independent of the patient's age, the patient's sex, the number of electrodes, the procedure of implantation, and even the time from implantation. As a result, the clinical diagnosis of occlusion is uncertain. Therefore, duplex sonography is recommended as an easy means of excluding a totally thrombosed subclavian vein prior to replacing pacemaker leads.     

Prospective Randomized Comparison of the Safety and Effectiveness of Placement of Endocardial Pacemaker and Defibrillator Leads Using the Extrathoracic Subclavian Vein Guided by Contrast Venography Versus the Cephalic Approach

CALKINS, H., et al. : Prospective Randomized Comparison of the Safety and Effectiveness of Placement of Endocardial Pacemaker and Defibrillator Leads Using the Extrathoracic Subclavian Vein Guided by Contrast Venography Versus the Cephalic Approach. The purpose of this prospective randomized study was to compare the safety and efficacy of the cephalic approach versus a contrast-guided extrathoracic approach for placement of endocardial leads. Despite an increased incidence of lead fracture, the intrathoracic subclavian approach remains the dominant approach for placement of pacemaker and implantable defibrillator leads. Although this complication can be prevented by lead placement in the cephalic vein or by lead placement in the extrathoracic subclavian or axillary vein, these approaches have not gained acceptance. A total of 200 patients were randomized to undergo placement of pacemaker or implantable defibrillator leads via the contrast-guided extrathoracic subclavian vein approach or the cephalic approach. Lead placement was accomplished in 99 of the 100 patients randomized to the extrathoracic subclavian vein approach as compared to 64 of 100 patients using the cephalic approach. In addition to a higher initial success rate, the extrathoracic subclavian vein medial approach was determined to be preferable as evidenced by a shorter procedure time and less blood loss. There was no difference in the incidence of complications. In conclusion, these results demonstrate that lead placement in the extrathoracic subclavian vein guided by contrast venography is effective and safe. It was also associated with no increased risk of complications as compared with the cephalic approach. These findings suggest that the contrast-guided approach to the extrathoracic portion of the subclavian vein should be considered as an alternative to the cephalic approach.     

Venous Access Thrombosis Detected by Transcutaneous Vascular Ultrasound in Patients with Single-Polyurethane-Lead Permanent Pacemaker

In order to assess the incidence of significant venous thrombosis after transvenous permanent pacemaker implantation, transcutaneous ultrasound studies were performed in 109 consecutive patients with single-polyurethane-lead pacemakers. Ultrasonic evaluation was found to be a good noninvasive method in assessing the veins. Six patients (5.5%) were found to have significant venous obstruction in the subclavian vein. However, none of them were symptomatic. No difference in the incidence of venous obstruction was found, based on the age, duration of implantation, operative technique, potentially thrombogenic factors including atrial fibrillation, diabetes mellitus, hypertension, heart failure and end-stage renal disease.     

Pacemaker Implantation in Children: A 21-Year Experience

Forty-one children, 20 hoys and 21 girls, aged 11 days to 19 years (mean 9.9 years) at initial pacemaker implant, were followed 1 to 248 months (mean 90 months). Ten (mean age 8.2 years) were implanted between 1966 and 1972 (Group I), 14 (mean age 9.9 years) between 1973 and 1980 (Group 11) and 17 (mean age 10.9 years) from 1981 through April 1988 (Group 111). Arrhythmias were congenital complete heart block in 19, postoperative heart block in 15, acquired heart block in 3, sick sinus syndrome in 3, and bradycardia-induced ventricular fibrillation in 1. Twenty-eight of 41 children had a transvenous implant: 40% of Group I, 71% of Group 11 and 82% of Group III. Thirteen were cephalic, four subclavian and 11 jugular. Generator site was pectoral in 19, abdominal in 12, intrathoracic in one, and retromammary in nine of 12 girls aged 10 years or more at implant. In Groups 1,11 and 111, 5, 14 and 6 had VOO or WI units; 5, 0 and 8 dual chamber (VAT, VDD and DDD) pacemakers; 0, 0 and 1 AAI; and 0, 0 and 2 rate-modulated (WIR) units at initial implant. The average interval between pacer-related hospitalizations in Groups I, II and III was 20, 42, and 39 months. Complications included infection in six, hemothorax in one, and impending pacemaker erosion in one. Six patients died, one of pacer infection, four from primary cardiac disease, and one suddenly without apparent reason. Follow-up continues in 31: 14 are employed full-time, three are homemakers, eight are full-time students, and six are active pre-schoolers. Four women have had normal children. We conclude: (1) children with implanted pacemakers can have a normal lifestyle, with prognosis based on underlying cardiac disease; (2) elective epicardial electrodes are now rarely needed; (3) implantation via the cephalic vein is feasible and complication-free; (4) retromammary implant is technically easy and cosmetic; (5) dual chamber and rate-modulated pacemakers can be utilized effectively.(PACE, Vol. 11 November Part II 1988)     

A New Approach to Percutaneous Subclavian Venipuncture to Avoid Lead Fracture or Central Venous Catheter Occlusion

Pacemaker and defibrillator leads and central venous catheters placed by commonly recommended techniques have been found to pass through the subclavius muscle, the costocaracoid ligament, or the costoclavicular ligament before entering veins medial to the first rib. Entrapment by these soft tissues subjects leads and catheters to stresses imposed by movements of the ipsilateral upper extremity. Accordingly, a new approach has been developed that introduces the lead or catheter into the subciavian vein near the lateral border of the first rib. This placement avoids soft tissue entrapment and may extend the longevity of leads and catheters.     

Double Target Method (Double Marker-Guided Extrathoracic Introducer Insertion)

Incidence of damage to pacemaker and implantable cardioverter defibrillator leads is an emerging problem that should be prevented. The extrathoracic venipuncture approach has been suggested as a technique for venous access to avoid the problem. This report describes the method of double marker-guided venipuncture of extrathoracic subclavian and/or axillary vein. This approach achieves definite, safe, and speedy extrathoracic venipuncture and may be especially suitable for multiple lead placement for cardiac resynchronization therapy. (PACE 2004; 27[Pt. I]:818–820)     

Clinical Experience with the Extrathoracic Introducer Insertion Technique

The extrathoracic approach to transvenous introducer insertion into the subclavian vein was initially described as an alternative approach in "Safe Introducer Technique for Pacemaker Lead Implantation." Since this technique was so successful as an alternative approach, it was tried as the primary approach in 213 consecutive cases. The subclavian vein was cannulated in all cases. There were no introducer related complications. The extrathoracic approach cannulates the subclavian vein as it passes over the body of the first rib prior to entering the thoracic inlet. The technique includes maneuvering the introducer needle from the clavicle to the first rib by a series of partial withdrawals and reinsertions, visualized by fluoroscopy, The needle is advanced posteriorly along the rib until the vein is punctured. Orientation is maintained by touching the rib with each maneuver. The early results of the extrathoracic approach reinforces the belief that a complication-free, transvenous introducer approach can he achieved.     

A cosmetic approach for pectoral pacemaker implantation in young girls

Pectoral placement of pacemaker generators, combined with use of a redundant intravascular lead portion, reduces the need for endocardial lead advancement during growth in children. While the use of small generators and submuscular pockets has contributed to cosmetic acceptability, the conventional subclavicular incision may occasionally form a keloid scar that is unacceptable in young girls. A modified implantation technique was used in five girls (age 2.6-13.3 years) during implantation of VDD (n = 2), VVIR (n = 2), and DDDR (n = 1) pacemakers. A 5-cm incision was made in the axilla along the line of the pectoralis major and dissection was continued below the muscle to create a pocket for the generator. Subclavian vein puncture was performed from the axillary incision and beneath the pectoralis major muscle using standard or extra long needles with a needle guard. Peel away sheaths were used for lead positioning. The generator was placed in the submuscular pocket and the wound closed with absorbable sutures. At follow-up, pacemaker function was excellent and neither the scars nor pacemakers were visible from the front. In conclusion, the axillary incision with direct subclavian vein puncture from below the pectoralis major muscle offers the advantages of pectoral pacemaker implantation through a single cosmetic incision.     

Transvenous Placement of a Pacemaker Lead Through an Introducer Despite Long-standing Subclavian-Vein Occlusion

Under ordinary circumstances complete chronic subclavian vein occlusion precludes using that vein for the pacemaker lead. There are circumstances, however, in which a patent vein beyond the obstruction can be reached with an introducer needle, thus permitting transvenous access similar to any other introducer-assisted implantation. A case exemplifying this point is described. Patency of the right subclavian vein beyond an occlusion was demonstrated by angiography, and a new dual-chamber pacemaker lead was inserted through that site by use of the introducer method.     

Use of the Contralateral Subclavian Vein for Placement of Atrial Electrodes in Chronically VVI Paced Patients

Two patients with documented pacemaker syndrome were referred for AV sequential pacing and were found to have inaccessible venous systems on the side of their original transvenous pacemaker placement. The confralateral subclavian vein was subsequently catheterized with an atrial electrode using the sheathset technique, Then the proximal aspecf of the atrial endocardial lead was tunneled to the original pacemaker pocket, Once accomplished, both (atrial and ventricular) leads were connected to an AV sequentiat pulse generafor. The united puise generalorand lead were reinserted in the original pacemaker pocket.     

Lead Failure Due to the Subclavian Crush Syndrome in a Patient Implanted with Both Standard and Thin Bipolar Spiral Wound Leads

Subclavian crush syndrome is a well-described cause of pacemaker lend failure resulting from an entrapment of a lead or leads between the clavicle and the first rib. A new thinner lead (Thin Line^tm) was designed to minimize this complication. Our patient de veloped atrial and ventricular lead subclavian crush syndrome with both conventional and thin leads.     

Course of Symptoms and Spontaneous ECG in Pacemaker Patients: A 5-Year Follow-up Study

We investigated the course of symptoms and the spontaneous ECG retrospectively in 308 patients who had received a pacemaker because of atrioventricular (AV) block (n = 115), sick sinus syndrome (SSS, n = 107), bradyarrhythmic atrial fibrillation (bradyarrhythmia, n = 51), carotid sinus syndrome (CSS, n = 16), complete bifascicular block associated with 1st degree AV block (n = 13) and with other indications (n = 6). The mean implantation time was 63 months. The clinical state of 93% of all patients improved after pacemaker implantation; their symptoms decreased markedly. Persisting syncopy in some patients with SSS, however, supports a restricted implantation policy. We rarely saw improved AV conduction in patients with AV block (11%). Furthermore, in patients with SSS, atrial fibrillation occurred significantly more often (35%) than in those with AV block (17%; P less than 0.01). Only 3% of patients with SSS developed 2nd and 3rd degree AV block within the observation period. In all patients with initial bifascicular block and additional 1st degree AV block, pacing prevented further syncopal attacks; four of them showed 3rd degree AV block at control, indicating that pacemaker implantation is mandatory in symptomatic patients with bifascicular disease and 1st degree AV block.     

Survival and Mortality in 3,701 Pacemaker Patients: Arguments in Favor of Pacemaker Reuse

This study analyzed the results of 3,701 patients implanted with cardiac pacemakers at the Centre Chirurgical du Val d'Or between 1976 and 1981. Two pacemaker populations were compared; those having a new pacemaker and (hose implanted with a reused pacemaker. There were no statistically significant differences between the two groups, either in terms of indications for implantation or in terms of actuarial survival of patients. In addition, there was no significant change in survival of the pulse generator. The reutilization of pacemakers appeared to be in no way detrimental to patients.     

Pacemaker Upgrade for Recurrent Pacemaker Syndrome Using a Redundant Contralateral Electrode in a Patient with Bilateral Venous Stenoses

Following His-bundle ablation and VVIR pacemaker implantation, severe pacemaker syndrome developed and was treated with DDDR pacing, in a 70-year-old woman. Due to bilateral subclavian vein stenoses, DDDR pacing could not be maintained and an unusual method of restoring atrioventricular synchrony is described using the contraiateral redundant atrial electrode connected to the ipsilateral dual chamber pacemaker and ventricular electrode.     

化疗期锁骨下中心静脉置管并发症的早期干预

目的 探讨肿瘤患者锁骨下中心静脉置管并发症的原因及防护措施。方法 总结2002年9月-2006年10月间为肿瘤内科患者行锁骨下中心静脉置管术320例,观察和记录各种并发症的发生,分析其原因及护理注意事项。结果 出现并发症36例,发生率为11．2％,其中气胸4例,误伤动脉3例,臂丛神经损伤2例,感染8例,导管脱落4例,导管堵塞12例,静脉血栓3例。经密切观察,及时发现,加强护理,均顺利恢复并完成治疗。结论 熟练掌握锁骨下中心静脉置管操作技能,严格把握禁忌证,建立持续监测系统,促进质量改善,实施全面的健康教育,可以大大降低中心静脉置管患者并发症的发生率。     

An Argument for Pacemaker Reuse: Pacemaker Mortality in 169 Patients over Ten Years

Retrospective examination of 169 consecutive pacemaker patient deaths was done to test the hypothesis that early mortality would preclude full utilization of current battery longevity. We found a 58% mortality within two years of the last generator implant. Nineteen percent occurred within six months, and 38% occurred within a year. This compares to a current clinic of 246 patients where 43% have utilized these pacemakers for greater than 48 months. The age comparison shows that those who died were older than the Jiving controls. The 58% 24-month mortality demonstrates that many patients underutilize expected battery life. The economic implications o/pacemaker reuse can then be understood.     

Safe Introducer Technique for Pacemaker Lead Implantation

Over the last several years, an introducer approach for pacemaker lead insertion has evolved that eliminates most introducer-related complications. The approach consists of defining a safe region for intrathoracic cannulation of the subclavian vein. If specific conditions cannot be met for entering the "safe" region or if the vein cannot be found, the subclavian vein is cannulated extrathoracically. Recently, this technique was used in 263 consecutive patients undergoing pacemaker implantation. The intrathoracic portion of the subclavian vein was used in 239 (90.9%) cases and the extrathoracic portion in 24 (9.1%). One hundred and ninety-eight (75.3%) cases were right-sided and 65 (24.7%) were left-sided. On the right side, 177 (89.4%) used the intrathoracic portion of the subclavian vein and 21 (10.6%) used the extrathoracic portion. On the left side, 62 (95.4%) used the intrathoracic portion and three (4.6%) used the extrathoracic. The introducer technique was successful in all cases and there were no introducer-related complications.     

Computer-Assisted Pacemaker Management Systems: Three Years of Clinical Experience

The implantation of large numbers of cardiac pacemakers and the increasing sophistication in engineering techniques has resulted in the demand for computer-assisted pacemaker management systems to remain on top of the available programmable features of the pacers as well as being able to access the follow-up data of pacemaker patients. A pacemaker patient management systems is introduced (PATIENTLOG™) that has been used in the clinical environment for a number of years. The menu-guided program is easy to handle and features a patient card for administration data, an implantation card for the technical data of the pacer, and a follow-up card where a large number of follow-ups can be stored side by side which are easily graphically displayable. An extensive statistical program, letter functions, automatic back-up and on-line communication with external equipment through an RS 232C interphase and a parallel adapter are available. The data base in Frankfurt holds 8,000 patients, 10,000 interventions and more than 30,000 follow-ups, the existing data base needs 20 M bytes storage space. Up to 96 different pacer types with their specific features can be introduced into the system. Software and hardware design complies with the recommendation of the NASPE Computer Committee.