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1.
Kirsten Sola Nina Brekke Mette Brekke 《Scandinavian journal of primary health care》2010,28(4):199-204
Objective
To investigate the feasibility and impact on BMI and physical fitness of an intervention for obese and inactive children, based on physical activity and carried out in primary health care.Design
A prospective, longitudinal one-year follow-up study.Setting
The community of Kristiansand, Norway (80 000 inhabitants).Intervention
A 40-week structured intervention based on physical training with some lifestyle advice for the obese child and one parent.Subjects
A total of 62 physically inactive children aged 6–14 years with iso-BMI ≥ 30 kg/m2.Main outcome measures
Body mass index (BMI), maximum oxygen uptake, and physical fitness in tests of running, jumping, throwing, and climbing assessed at baseline and after six and 12 months as well as number of dropouts and predicting factors.Results
A total of 49 out of 62 children completed the first six months and 37 children completed 12 months. Dropout rate was higher when parents reported being physically inactive at baseline or avoided physical participation in the intervention. The children''s maximum oxygen uptake increased significantly after 12 months from 27.0 to 32.0 ml/kg/min (means), as did physical fitness (endurance, speed, agility, coordination, balance, strength) and BMI was significantly reduced.Conclusion/implications
This one-year activity-based intervention for obese and inactive children performed in primary health care succeeded by increasing cardiovascular capacity and physical fitness combined with reduced BMI in those who completed. Dropout was substantial and depended on the attendance and compliance with physical activity by the parents.Key Words: BMI, childhood obesity, dropouts, family practice, fitness, parental participation, physical activity, primary careFew studies have presented intervention models for obesity among children organized by GPs. Our study focusing on physical activity showed:- Effect on BMI and physical fitness after six months and after 12 months;
- A high dropout rate among the children, related to parents’ compliance and lifestyle;
- The child''s adherence to the training programme mainly depended on the attendance of the parents.
2.
Johansen ML Holtedahl KA Rudebeck CE 《Scandinavian journal of primary health care》2010,28(4):249-255
Objective
To explore GPs’ own views on their role in cancer care.Design
Qualitative study based on semi-structured interviews.Setting
Norwegian primary care.Methods
The stories of 14 GPs concerning 18 patients were analyzed for core content and abstracted into general ideas, to create a broader sense of the experienced professional role.Results
The GPs claimed to have an important role in cancer care. In our analysis, three main aspects of GPs’ work emerged: first, as a flexible mediator, e.g. between the patient and the clinic, interpreting and translating; second, as an efficient “handyman”, solving practical problems locally; and third, as a personal companion for the patient throughout the illness.Conclusion
The interviewed GPs see their place in cancer care as being close to their patients. In their many tasks we found three main aspects: the mediating, the practical, and the personal.Key Words: Family practice, neoplasms, primary health care, professional role, qualitative researchGPs can be seen in cancer treatment as either peripheral or having a unique role, offering continuity of care and information throughout the illness.- GPs can accompany patients through the whole cancer journey.
- GPs talk about significant tasks in interpreting illness, mediating in the healthcare system, and handling many practical issues.
- Support of seriously ill patients and their families is seen both as very challenging and as deeply meaningful work.
- How do they perceive and describe their place in health care for people with cancer?
- What are the challenges and dilemmas that they face?
3.
Ingrid Wikstrand Jarl Torgerson Kristina Bengtsson Bostr?m 《Scandinavian journal of primary health care》2010,28(2):89-94
Objective
The primary objective was to investigate the feasibility and cost-effectiveness of weight reduction using very low calorie diet (VLCD) in groups. The secondary objective was to investigate whether subsequent corset treatment could maintain the weight reduction long term.Design
Participants, consecutively included in groups of 8–14 subjects, underwent three months of VLCD with lifestyle advice at group meetings. Subjects attaining ≥ 8 kg reduction were randomized to corset (A) or no corset (B) treatment for nine months. Weight was registered at all meetings and after 24 months. Costs were calculated using current salaries and anti-obesity drug prices as at 2008.Settings
Primary care in Skaraborg, Sweden.Subjects
A total of 26 men and 65 women aged 30–60 years with BMI ≥ 30−< 45 kg/m2.Main outcome measures
Weight changes and costs of treatment.Results
VLCD (dropout n = 14) resulted in a mean weight reduction of 20.1±6.6 kg (20 men) and 15.7±4.7 kg (57 women). These 77 subjects were randomized to treatment A (n = 39) or B (n = 38). Compliance with corset was only 20% after three months. After one year (dropout n = 17) weight loss was 11.7±8.1 kg (A) and 9.3±6.9 kg (B), p = 0.23 and after two years (dropout n = 22) 6.1±7.0 kg and 4.4±7.3 kg respectively, p = 0.94. Serum glucose and lipids were altered favourably. The cost per participant of treatments A and B was SEK 4440 and SEK 1940 respectively.Conclusions
VLCD in groups was feasible and reduced weight even after one year. The cost of treatment was lower than drug treatment. Corset treatment suffered from poor compliance and could therefore not be evaluated.Key Words: Family practice, group treatment, obesity, primary care, very low calorie dietVery low calorie diet (VLCD), mainly used as an individual treatment in specialized clinics, gives a substantial weight reduction but weight is often soon regained.- VLCD during a three-month period in primary care was well accepted, and effective. It gave a similar weight reduction to when used in specialised clinics and reduced weight even after one year.
- Corset treatment for nine months to maintain weight reduction could not be evaluated due to poor compliance.
- The cost of VLCD treatment and group sessions with lifestyle advice was lower compared with pharmacological treatment.
4.
Kaisa Turunen Markku Sumanen Riitta-Liisa Haukilahti Pertti Kirkinen Kari Mattila 《Scandinavian journal of primary health care》2010,28(2):102-107
Objective
Pregnant women complaining of itching are screened for intrahepatic cholestasis (ICP) by laboratory tests in primary healthcare. Cases of ICP are referred to specialist care. In Finland, ICP occurs in 1% of pregnancies. The aim was to study the outcome of deliveries.Design
Retrospective study of ICP pregnancies. Data were collected from the hospital discharge register, patient records, and the labour register.Setting
The region of Tampere University Hospital in Finland.Subjects
Altogether 687 ICP cases from 1969 to 1988 and two controls for each.Main outcome measures
ICP patients were compared with controls in terms of mother''s age, pregnancy multiplicity, weeks of gestation at delivery, frequency of induction and Caesarean section, length of ward period, child''s weight, Apgar scores, and stillbirth.Results
For ICP patients, the risk for hospital stay of 10 days or more was eightfold (OR 8.41), for gestational weeks less than 37 at delivery sevenfold (OR 7.02), for induction threefold (OR 3.26), for baby''s low weight at birth almost twofold (OR 1.86), and for Caesarean section one and a half fold (OR 1.47). The possibility of the incidence of multiple pregnancy was two and a half fold (OR 2.49, 95%). ICP was not associated with mother''s age, the baby''s risk of stillbirth, or low Apgar scores.Conclusion
ICP mothers are found and taken care of appropriately, and thus ICP is only a minor risk for mothers and their children.Key Words: Caesarean section, intrahepatic cholestasis, length of stay, pregnancy outcome, primary healthcareIntrahepatic cholestasis of pregnancy (ICP) contains risks for the foetus. It is important that ICP cases are detected in primary healthcare.- ICP mothers’ ages did not differ significantly from others.
- Childbirth happened at earlier weeks of gestation in ICPs, but Apgar scores were only slightly lower.
- In ICP cases labour induction and Caesarean section were more common and hospital stay was significantly longer.
5.
Westerdahl C Bergenfelz A Isaksson A Nerbrand C Valdemarsson S 《Scandinavian journal of primary health care》2011,29(1):57-62
Objective
To evaluate the prevalence of primary aldosteronism (PA) in newly diagnosed and untreated hypertensive patients in primary care using the aldosterone/renin ratio (ARR), and to assess clinical and biochemical characteristics in patients with high and normal ARR.Design
Patient survey study.Setting and subjects
A total of 200 consecutive patients with newly diagnosed and untreated hypertension from six primary health care centres in Sweden were included.Main outcome measures
ARR was calculated from serum aldosterone and plasma renin concentrations. The cut-off level for ARR was 65. Patients with an increased ARR were considered for confirmatory testing with the fludrocortisone suppression test (FST), followed by adrenal computed tomographic radiology (CT) and adrenal venous sampling (AVS).Results
Of 200 patients, 36 patients had an ARR > 65. Of these 36 patients, 11 patients had an incomplete aldosterone inhibition during FST. Three patients were diagnosed with an aldosterone producing adenoma (APA) and eight with bilateral adrenal hyperplasia (BHA). Except for moderately lower level of P-K in patients with an ARR > 65 and in patients with PA, there were no biochemical or clinical differences found among hypertensive patients with PA compared with patients without PA.Conclusion
Eleven of 200 evaluated patients (5.5%) were considered to have PA. The diagnosis of PA should therefore be considered in newly diagnosed hypertensive subjects and screening for the diagnosis is warranted.Key Words: Aldosterone, aldosterone to renin ratio, family practice, hypertension, primary aldosteronism, reninPrimary aldosteronism (PA) is common in patients diagnosed with “essential hypertension” in specialized centres; however, reports on prevalence in primary care are few.- Screening with the aldosterone to renin ratio followed by confirmatory testing showed that 5.5% of newly diagnosed and untreated hypertensive patients had PA.
- No particular clinical features could distinguish these patients from patients with essential hypertension.
- Screening for PA should always be performed in younger patients with newly diagnosed hypertension and in patients with resistant hypertension irrespective of potassium concentrations.
6.
Objective
Using validated screening instruments to detect depressive symptoms in the elderly has been recommended. The aim of this study was to compare a patient-centred consultation model with the PRIME-MD screening questionnaire, using the MADRS-S as reference for detecting depressive symptoms in an elderly primary care population.Design
Comparative study.Setting
Primary care, Sweden.Subjects
During an 11-month period 302 consecutive patients aged 60 and over attending a primary care centre were screened with the PRIME-MD and the Montgomery-Asberg Depression Rating Scale-Self-rated version (MADRS-S) instrument. The results were unknown to the GPs who used a structured, patient-centred consultation model comprising seven open-ended “key questions”.Main outcome measures
Sensitivity, specificity, positive predictive values (PPV), and negative predictive values (NPV) were calculated for the PRIME-MD screening questionnaire and the patient-centred consultation model using MADRS-S as reference for possible depression at two cut-off levels with 15% prevalence.Results
Sensitivity was lower for the consultation model than the PRIME-MD screening questionnaire: 78% and 98%, respectively. The GPs failed to identify every fifth patient using the lower cut-off (MADRS-S≥13) but the number of required diagnostic interviews decreased by almost 50%: 85 versus 162, respectively. PPV was 43% and 28%, respectively. Both instruments showed high sensitivity (93%) using the higher cut-off (MADRS-S≥20) and had high NPV: 95% and 99%, respectively.Conclusions
The findings suggest that the consultation screening procedure might be as useful in everyday practice as the PRIME-MD screening questionnaire. Both screening procedures may also be useful for ruling out depressive symptoms.Key Words: Depressive symptoms, elderly, family practice, primary care, screening instrumentsTo enhance the detection of elderly patients with depression the use of screening instruments has been recommended. In this study a patient-centred consultation model was used as a screening procedure for detecting depressive symptoms and its performance was compared with the validated screening questionnaire of the PRIME-MD instrument.- The patient-centred consultation has acceptable properties and is well functioning in the GP''s clinical situation in which patient-centredness plays an essential role in the diagnostics.
- The contexts of the presented symptoms need to be considered in relation to psychological, physical, and social factors before the assessment.
7.
Janne Fangel Jensen Louise Lindhardt T?nnesen Margareta S?derstr?m Hanne Thorsen Volkert Siersma 《Scandinavian journal of primary health care》2010,28(2):115-120
Objective
The sale of paracetamol products for children is increasing, and more children are accidentally given overdoses, even though the use of paracetamol against fever is still under discussion. This study explores Danish parents’ use of paracetamol for feverish children and their motives for this use.Design
A cross-sectional survey using structured interviews.Setting
Four general practices located in city, suburb, and rural area.Subjects
A total of 100 Danish parents with at least one child under the age of 10 years.Main outcome measures
Number of parents administering paracetamol to feverish children, situations triggering medication of a child, parental views regarding fever and effects of paracetamol, and sources of information on fever treatment.Results
Three in four parents use paracetamol for feverish children, mainly to reduce temperature, to decrease pain, and to help the child fall asleep. Highly educated parents medicate more often than less educated. Parents often fear fever but this does not clearly affect their use of paracetamol. Many parents believe in perceived beneficial effects of paracetamol, such as increased appetite and well-being, better sleep, and prevention of fever seizures. These expectations of paracetamol influence parental use of the drug. Parents’ main source of information on fever and paracetamol is their general practitioner (GP).Conclusions
Danish parents regularly treat feverish children with paracetamol. Although parents contact their GP for advice on fever treatment, paracetamol is sometimes given to children on vague indications. Clearer information for parents on when to give paracetamol as fever treatment may help regulate its use.Key Words: Antipyretic, children, family practice, fever, gender, paracetamol, parents, primary healthcareThe sale of child-friendly paracetamol products is increasing in Denmark, even though use of paracetamol as treatment of fever is still being debated.- Parents give paracetamol to improve well-being, appetite, and sleep of feverish children – research only vaguely supports this use.
- Highly educated parents medicate more often than less educated.
- Danish parents’ main source of information concerning fever and its treatment is their general practitioner.
- to what extent and in which situations parents give their children antipyretics;
- if parental views of the effects of paracetamol are consistent with existing evidence, and if their views influence the use of the drug;
- if fever phobia is present among parents and if it motivates them to give paracetamol;
- where parents seek information on handling a feverish child.
8.
9.
Andrew M. Garratt Kirsten Danielsen Oddvar Forland Steinar Hunskaar 《Scandinavian journal of primary health care》2010,28(2):95-101
Objective
To develop and evaluate the Patient Experiences Questionnaire for Out-of-Hours Care (PEQ-OHC) in Norway.Design
Questionnaire development was based on a systematic literature review of existing questionnaires, interviews with users, and expert group consultation. Questionnaire testing followed a postal survey of users who had attended out-of-hours centres in the North, West, and South of Norway.Setting
Primary care out-of-hours services.Subjects
The questionnaire was pre-tested with 13 users and was then mailed to 542 users who had had telephone contact and/or had a consultation with one of three out-of-hours centres.Main outcome measures
Data quality, internal consistency, reliability, and construct validity.Results
The questionnaire was considered to have good content validity by the expert group. There were 225 (41.51%) respondents to the postal questionnaire. Levels of missing data at the item and scale level were acceptable. Principal component analysis supported the four scales of user experiences relating to telephone contact, doctor services, nursing services, and organization. Item-total correlations were all above 0.5 and Cronbach''s alpha was above 0.80 for all scales. Statistically significant associations based on explicit hypotheses were evidence for the construct validity of the PEQ-OHC.Conclusion
The development of the PEQ-OHC followed a rigorous process based on a systematic review, interviews with users, and an expert group which lend the questionnaire content validity. The PEQ-OHC has evidence for data quality, internal consistency, reliability, and construct validity.Key Words: Family practice, out-of-hours, patient satisfaction, questionnaire, reliability, survey, validityQuestionnaires are increasingly used for assessing patient experiences of out-of-hours care.- Existing questionnaires have limitations relating to data quality, reliability, and validity.
- The PEQ-OHC has undergone a rigorous process of development following a systematic review and interviews with patients.
- The PEQ-OHC has good evidence for data quality, reliability, and validity.
10.
Objective
To explore the influence of sociodemographic factors on access to appointments with physicians in primary, secondary, and tertiary health care in a publicly funded health care system.Design
A population-based registry study.Setting
Different health care settings in Västernorrland county, Sweden.Subjects
All residents in the county at the end of 2006.Main outcome measures
The number of people per 1000 residents who had at least one appointment with a physician in an average month in different health care settings.Results
A total of 87 people had appointments with a physician in primary health care, 44 in outpatient clinics at a regional hospital, 20 in an emergency department, 14 in home care, and two in a university hospital outpatient clinic. Twelve were hospitalized at a regional hospital and <1 at the university hospital. Being young or elderly, female, divorced, widowed, and having a contractor as usual source of care were all independently associated with higher odds of receiving primary care.Conclusions
The physician''s office in primary care is the setting that has the potential to affect the largest number of people. The extent of the use of health care was independently influenced by all sociodemographic characteristics studied, which highlights the importance of individual factors in future resource allocation. Regarding availability the ecology model provides superior information as compared with the absolute number of physicians'' appointments. The prerequisites in Sweden of high-quality registries and unique personal identification numbers encourage future research on the ecology model to optimize accessibility of health care.Key Words: Delivery of health care, health services research, medical ecology, resource allocationThe medical ecology model has been used to assess health care use in private and mixed-finance systems but not in publicly funded systems. In the present study of a publicly funded health care system highly reliable population-based registers on an individual level were used.- The physician''s office in primary care is the setting that has the potential to affect the largest number of people.
- Sociodemographic characteristics influenced the proportion of physician appointments, which highlights the importance of individual factors in future resource allocation.
11.
Mariko Teramura-Gr?nblad Helka Hosia-Randell Seija Muurinen Kaisu Pitkala 《Scandinavian journal of primary health care》2010,28(3):154-159
Objective
The aim of this study is to investigate the use of proton-pump inhibitors (PPI) and their associated risks among frail elderly nursing home residents.Design
A cross-sectional study.Setting
General practice.Subjects
An assessment of residents (n = 1987, mean age 83.7 years) in all nursing homes in Helsinki was carried out in February 2003. Data included demographic characteristics, symptoms such as diarrhea, vomiting and constipation, use of various drugs, and medical diagnoses.Outcome
Coded data analysis with NCSS statistical program. Multivariate logistic regression analysis served to determine which variables were independently associated with diarrhea; variables which were statistically significant or near p < 0.05 in univariate analyses were included.Results
Altogether 433 residents were on PPIs. The factors associated with regular PPI use in univariate analyses included poor functional status, higher number of comorbidities, higher number of medications and lactose intolerance. The users had suffered from a prior ventricular or duodenal ulcer, cancer and coronary heart disease more often than the non-users. In accordance with our hypothesis, the users of PPIs more often had diarrhea (19.7%) than the non-users (12.9%) (p < 0.001), and they had a prior hip fracture (28.5%) more often than the non-users (19.4%) (p < 0.001). In logistic regression analysis the use of PPIs had an independent association with diarrhea (OR 1.60 (95% CI 1.20 to 2.15).Conclusion
Physicians should avoid unnecessary long-term use of PPIs, particularly among frail elderly long-term care patients.Key Words: Aged, diarrhea, family practice, hip fracture, proton pump inhibitors, risksThe well-known benefits of proton-pump inhibitors (PPIs) have led to their increased and long-term use as “all purpose” protectors of the GI tract among older patients.- Among nursing home residents 22% were administered PPIs regularly.
- Regular PPI use was associated with diarrhea, prior hip fracture, coronary heart disease, and lactose intolerance indicating possible adverse events or their use for inappropriate therapeutic intent.
- Unnecessary long-term use of PPIs should be avoided among frail, older patients.
12.
Lars Rytter Helle Neel Jakobsen Finn R?nholt Anna Viola Hammer Anne Helms Andreasen Aase Nissen Jakob Kjellberg 《Scandinavian journal of primary health care》2010,28(3):146-153
Objectives
Many hospital admissions are due to inappropriate medical treatment, and discharge of fragile elderly patients involves a high risk of readmission. The present study aimed to assess whether a follow-up programme undertaken by GPs and district nurses could improve the quality of the medical treatment and reduce the risk of readmission of elderly newly discharged patients.Design and setting
The patients were randomized to either an intervention group receiving a structured home visit by the GP and the district nurse one week after discharge followed by two contacts after three and eight weeks, or to a control group receiving the usual care.Patients
A total of 331 patients aged 78+ years discharged from Glostrup Hospital, Denmark, were included.Main outcome measures
Readmission rate within 26 weeks after discharge among all randomized patients. Control of medication, evaluated 12 weeks after discharge on 293 (89%) of the patients by an interview at home and by a questionnaire to the GP.Results
Control-group patients were more likely to be readmitted than intervention-group patients (52% v 40%; p = 0.03). In the intervention group, the proportions of patients who used prescribed medication of which the GP was unaware (48% vs. 34%; p = 0.02) and who did not take the medication prescribed by the GP (39% vs. 28%; p = 0.05) were smaller than in the control group.Conclusion
The intervention shows a possible framework securing the follow-up on elderly patients after discharge by reducing the readmission risk and improving medication control.Key Words: Discharge, elderly, family practice, home visit, medication, primary care, readmissionFewer readmissions and better control of medication is generally strived for. A follow-up programme by the GPs and district nurses after discharge found:- A 23% relative readmission risk reduction within six months after discharge.
- Better follow-up including better control of medication after discharge.
- A cost-neutral intervention featuring a tendency towards reduced costs.
13.
Nielsen AB Gannik D Siersma V Olivarius Nde F 《Scandinavian journal of primary health care》2011,29(3):157-164
Objective
Improving glycaemic control is generally supposed to reduce symptoms experienced by type 2 diabetic patients, but the relationships between glycated haemoglobin (HbA1c), diabetes-related symptoms, and self-rated health (SRH) are unclarified. This study explored the relationships between these aspects of diabetes control.Design
A cross-sectional study one year after diagnosis of type 2 diabetes.Subjects
A population-based sample of 606 type 2 diabetic patients, median age 65.6 years at diagnosis, regularly reviewed in primary care.Main outcome measures
The relationships between HbA1c, diabetes-related symptoms, and SRH.Results
The patients’ median HbA1c was 7.8 (reference interval: 5.4–7.4 % at the time of the study). 270 (45.2%) reported diabetes-related symptoms within the past 14 days. SRH was associated with symptom score (γ = 0.30, p < 0.001) and HbA1c (γ = 0.17, p = 0.038) after correction for covariates. The relation between HbA1c and symptom score was explained by SRH together with other confounders, e.g. hypertension (γ = 0.02, p = 0.40). The relation between the symptom fatigue and SRH was not explained by symptom score and significantly modified the direct association between symptom score and SRH.Conclusions
Symptom relief may not occur even when HbA1c level is at its lowest average level in the natural history of diabetes, and symptoms and SRH are closely linked. Monitoring symptoms in the clinical encounter to extend information on disease severity, as measured e.g. by HbA1c, may help general practitioners and patients to understand the possible impact of treatments and of disease manifestations in order to obtain optimum disease control.Key Words: Family practice, glycosylated haemoglobin A, health status, signs and symptoms, type 2 diabetes mellitusTo reduce complications, lowering of HbA1c is a primary objective in diabetes care.- Many patients experience diabetes-related symptoms in spite of acceptable glycaemic control.
- These symptoms are closely related to poor SRH while the association with HbA1c is weak.
14.
Objective
To study one-year incidence and risk factors of severe hypoglycaemias (SH) in adult drug-treated diabetic patients living in two Finnish communities.Design
The episodes of SH and their risk factors were identified from local ambulance registers, from the databases of local health care units, and from patient questionnaires.Setting
The target population consisted of all drug-treated diabetic patients from the two middle-sized communities in southern Finland, altogether 1776 patients. The study was retrospective.Subjects
A total of 1469 patients (82.7% of the target population) gave informed consent for the use of their medical records and 1325 patients (74.6% of the target population) returned the detailed 36-item questionnaire.Results
Of type 1 and type 2 insulin-treated diabetic patients, 14.6% and 1.0%, respectively, needed ambulance or emergency room care (incidence of 30.5 and 3.0 per 100 patient years). However, 31.0% of type 1 and 12.3% of type 2 diabetic patients reported at least one episode of SH (incidence of 72.0 and 27.0 per 100 patient years). Of all insulin-treated patients, 53 (7.8%) reported three or more episodes of SH. Significant independent risk factors for SH were depression, daily exercise, and nephropathy but not glycaemic control.Conclusion
The incidence of SH was high in both types of insulin-treated diabetic patients. However, the recurrent episodes of SH were clustered in a small minority of insulin-treated patients with diabetes. The risk of SH should be considered when assessing the treatment target for an individual diabetic patient.Key Words: Insulin-treated diabetes, oral antidiabetic therapy, severe hypoglycaemia, type 1 diabetes, type 2 diabetesThe risk of severe hypoglycaemia (SH) has not been thought to be a problem in the treatment of type 2 diabetes.- In this population-based study cohort severe hypoglycaemias in both type 1 and type 2 insulin-treated diabetic patients seemed to be more common than previously thought.
- Severe hypoglycaemias seem, however, to be clustered in a small minority of insulin-treated diabetic patients.
- The risk of severe hypoglycaemia should be considered when assessing the treatment target for an individual diabetic patient.
15.
Paul H. H. Houben Ron A. G. Winkens Trudy van der Weijden Renee C. R. M. Vossen André J. M. Naus Richard P. T. M. Grol 《Scandinavian journal of primary health care》2010,28(1):18-23
Objective
Laboratory tests are ordered on a daily basis, even though disease probability is often very low. Abnormal results, especially mildly abnormal results, can be difficult to interpret in these circumstances. Further insights into the occurrence of abnormalities can help improve rational test ordering and test interpretation. The objective was therefore to examine the frequency of mildly and markedly abnormal results and their relationship with physicians'' reasons for ordering tests.Design
Prospective study.Participants
A total of 87 primary care physicians in the Netherlands collected data on 1775 patients.Main outcome measures
The physicians recorded the reason for ordering the tests, the most probable diagnosis and the pretest probability. The laboratories'' reference values and specified “action limits” were used to assess the number of abnormal results and markedly abnormal results, respectively.Results
Laboratory results were received for 1621 patients and 15,603 tests were reported (mean 9.6). The proportion of abnormal test results increased with increasing pretest probability (from 13.9% to 34.7%) and was 13.4% for tests ordered to reassure the patient and 13.3% for psychosocial diagnoses. The proportion of patients with at least one abnormal test result was high: 53.1% for tests ordered to reassure and 57.7% in patients with low pretest probability. Corresponding values for a marked abnormality were 11.1% and 12.4%, respectively.Conclusion
Abnormal laboratory test results were frequent, even when pretest probability was low. Physicians should therefore carefully consider when tests are necessary. Future research could explore physicians'' interpretation of test results and its impact on diagnosis and management.Key Words: Clinical chemistry tests, diagnostic tests, family practice, interpretation of laboratory tests, laboratory utilization, primary healthcareTests are often ordered even though disease probability is low. The frequency of abnormal results in these situations was unknown.- Even when tested for reasons such as “patient reassurance”, many patients have abnormal results.
- Most abnormalities are only slightly abnormal.
- Physicians should carefully consider when tests are necessary. Future research could explore the interpretation of results and the impact on diagnosis and management.
16.
Ingrid H. Johansen Tone Morken Steinar Hunskaar 《Scandinavian journal of primary health care》2010,28(3):160-165
Objective
To investigate prevalence, diagnostic patterns, and parallel use of daytime versus out-of-hours primary health care in a defined population (n = 23,607) in relation to mental illness including substance misuse.Design
Cross-sectional observational study.Setting
A Norwegian rural general practice cooperative providing out-of-hours care (i.e. casualty clinic) and regular general practitioners’ daytime practices (i.e. rGP surgeries) in the same catchment area.Subjects
Patients seeking medical care during daytime and out-of-hours in 2006.Main outcome measures
Patients’ diagnoses, age, gender, time of contact, and parallel use of the two services.Results
Diagnoses related to mental illness were given in 2.2% (n = 265) of encounters at the casualty clinic and in 8.9% (n = 5799) of encounters at rGP surgeries. Proportions of diagnoses related to suicidal behaviour, substance misuse, or psychosis were twice as large at the casualty clinic than at rGP surgeries. More visits to the casualty clinic occurred in months with fewer visits to rGP surgeries. Most patients with a diagnosis related to mental illness at the casualty clinic had been in contact with their rGP during the study period.Conclusion
Psychiatric illness and substance misuse have lower presentation rates at casualty clinics than at rGP surgeries. The distribution of psychiatric diagnoses differs between the services, and more serious mental illness is presented out-of-hours. The casualty clinic seems to be an important complement to other medical services for some patients with recognized mental problems.Key Words: After-hours care, emergency medical services, family practice, physician''s practice patterns, primary health care, psychiatryMost mentally ill patients in Norway are dealt with by the primary health care system, and out-of-hours GP services are the main source of acute referrals to psychiatric wards. Differences between daytime and out-of-hours services regarding relative prevalence, diagnostic challenges, and parallel use have previously been unknown.- Prevalence of diagnoses related to mental illness is lower at out-of-hours services compared with daytime services. However, suicidal behaviour, substance misuse, and psychosis are more prevalent out-of-hours than during the daytime.
- Use of out-of-hours services increases in periods with low use of daytime services.
- Most patients with diagnoses related to mental illness out-of-hours had also seen their regular general practitioner during the study period.
17.
Objective
To explore the negative predictive value (NPV), positive predictive value (PPV), sensitivity, and specificity of natriuretic peptides, cut-off levels, and the impact of gender and age in elderly patients with systolic heart failure (HF).Design
Cross-sectional exploratory study.Setting
One primary healthcare centre.Patients
A total of 109 patients with symptoms of HF were referred for echocardiographic examination with a cardiovascular consultation. Systolic HF was diagnosed (ESC guidelines) in 48 patients (46% men, 54% women, mean age 79 years) while 61 patients (21% men, 79% women, mean age 76 years) had no HF.Main outcome measures
NPV, PPV, sensitivity, specificity, and cut-off levels.Results
Including all 109 patients, NPV was 88% for NT-proBNP (200 ng/L) and 87% for BNP (20 pg/ml). PPV was 81% for NT-proBNP (500 ng/L) and 68% for BNP (50 pg/ml). Sensitivity was 96% for NT-proBNP (100 ng/L) and 96% for BNP (10-20 pg/ml). Specificity was 87% for NT-proBNP (500 ng/L) and 71% for BNP (50 pg/ml). Nt-proBNP (β = 0.035; p < 0.001) and BNP (β = 0.030; p < 0.001) were associated with age, but not with gender. In a multivariate analysis age (β = 0.036; p < 0.001) and male gender (β = 0.270; p = 0.014) were associated with NT-proBNP, but only age for BNP (β = 0.030; p < 0.001).Conclusion
Natriuretic peptides in an elderly population showed high NPVs, but not as high as in younger patients with HF in other studies. Age and male gender were associated with higher levels of NT-proBNP while only age was related to elevated BNP levels.Key Words: Echocardiography, elderly, family practice, gender, natriuretic peptides, primary health care, systolic heart failureKnowledge of the utility of natriuretic peptides in elderly patients with suspected heart failure in primary healthcare is still limited.- Natriuretic peptides showed high negative predictive values, but not as high as in younger patients with heart failure in other studies.
- Natriuretic peptides are useful as diagnostics tools even in elderly patients but the most precise cut-off levels still have to be determined.
- Age and male gender were associated with higher levels of NT-proBNP, while only age was related to elevated BNP levels.
18.
Marina Taloyan Alexandre Wajngot Sven-Erik Johansson Jonas Tovi Jan Sundquist 《Scandinavian journal of primary health care》2010,28(4):216-220
Objective
Several studies indicate that ethnicity may be a strong predictor of poor self-rated health (SRH). The aims of the present study were to investigate whether there was an association between ethnicity and poor SRH in subjects with type 2 diabetes and to determine if the association remained after adjusting for possible confounders such as age, gender employment, marital status, and education.Design
A cross-sectional study based on a patient population in the town of Södertälje. An unconditional logistic regression was performed to estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs).Setting
Four primary health care centers.Subjects
A total of 354 individuals were included: Assyrian/Syrian-born (n = 173) and Swedish-born (n = 181).Results
The odds ratio for rating poor SRH for Assyrian/Syrian subjects with type 2 diabetes was 4.5 times higher (95% CI = 2.7–7.5) than for Swedish patients in a crude model. After adjusting for possible confounders, unemployed/retired people had 5.4 times higher odds for reporting poor SRH than employees (OR = 5.4; 95% CI = 2.3–12.5). Women had 1.8 times higher odds (95% CI = 1.0–3.0) for reporting poor SRH than men. In the final model poor SRH among Assyrians/Syrians decreased but still remained significant (OR=3.7; 95% CI = 2.5–6.6).Conclusions
The findings in this study are important for planning primary health care services. They highlight the crucial importance of being aware of the subjective health status of immigrants fleeing from war in the Middle East and resettling in Sweden.Key Words: Assyrians/Syrians, ethnicity, self-rated health, type 2 diabetesThis study highlights the relationship between self-rated health and ethnicity in subjects with type 2 diabetes.- Socioeconomic factors did not explain the ethnic differences in rating poor general health.
- Unemployed/retired patients with type 2 diabetes, regardless of ethnicity, had the highest odds ratio for reporting poor general health.
19.
20.
Stein Nilsen Erik L?nnmark Werner Silje Maeland Hege Randi Eriksen Liv Heide Magnussen 《Scandinavian journal of primary health care》2011,29(1):7-12
Objectives
To explore GPs’ considerations in decision-making regarding sick-listing of patients suffering from SHC.Design
Qualitative analysis of data from nine focus-group interviews.Setting
Three cities in different regions of Norway.Participants
A total of 48 GPs (31 men, 17 women; aged 32–65) participated. The GPs were recruited when invited to a course dealing with diagnostic practice and assessment of sickness certificates related to patients with composite SHCs.Results
Decisions on sick-listing patients with SHCs were regarded as a very challenging task. Trust in the patient''s own story and self-judgement was deemed crucial, but many GPs missed hard evidence of illness and loss of function. Several factors that might influence decision-making were identified: the patients’ ability to present their story to evoke sympathy, the GP''s prior knowledge of the patient, and the GPs’ own experience as a patient and their tendency to avoid conflicts. The approach to the task of sick-listing differed from patient-led cooperation to resistant confrontation.Conclusion and implications
Issuing sickness certification in patients with composite health complaints is considered challenging and burdensome. It is seen as mainly patient-driven, and the decisions vary according to GPs’ attitudes, beliefs, and personalities. Guiding the GPs to a more focused awareness of the decision process should be considered.Key Words: Education, family practice, primary health care, sickness certification, sick-listing, subjective health complaints, work incapacityAlthough we have some knowledge concerning GPs’ practices on sick-listing in general, less is known about how GPs make their assessments regarding sick-listing in the more complex cases of patients with subjective health complaints (SHCs).- Decisions on sick-listing patients with SHCs are considered by GPs as a demanding and challenging task and are seen as mainly patient-driven.
- Handling of the sick leave decisions varies greatly, according to GPs’ attitudes, beliefs, and personalities.
- Focused awareness of the decision process through more specific education and training among students and GPs should be considered.