联合强脉冲光和射频治疗面部雀斑的临床研究

目的探讨联合强脉冲光和射频对雀斑的临床疗效及安全性。方法对150例患者进行临床研究,采取联合强脉冲光和射频治疗,每21d治疗1次,共3~5次,治疗前后观察疗效。结果150例雀斑患者经过3~5次治疗后,52例痊愈,58例显效,34例好转,6例无效,显效率为73.3%,有效率为96.0%。结论联合强脉冲光和射频对雀斑治疗疗效显著,安全性高,值得临床推广应用。     

联合强脉冲光和射频治疗面部雀斑的临床研究

目的探讨联合强脉冲光和射频对雀斑的临床疗效及安全性。方法对150例患者进行临床研究，采取联合强脉冲光和射频治疗，每21d治疗1次，共3～5次，治疗前后观察疗效。结果150例雀斑患者经过3-5次治疗后，52例痊愈，58例显效，34例好转，6例无效，显效率为73．3％，有效率为96．0％。结论联合强脉冲光和射频对雀斑治疗疗效显著，安全性高，值得临床推广应用。     

强脉冲光联合Q532nm激光治疗雀斑120例临床观察

目的:观察飞顿LovelyⅡ强脉冲光联合Medlite C6 Q532nm激光治疗雀斑的疗效。方法:120例雀斑患者,采用LovelyⅡ强脉冲光及Medlite C6 Q532nm激光联合治疗3次,每次间隔4周。结果:120例雀斑患者经过3次联合治疗后,103例(85.8%)痊愈,15例(12.5%)显效,2例(1.7%)有效,总有效率为100%,5例(4.2%)出现色素沉着。所有患者面部皮肤较以前光滑、细腻。结论:LovelyⅡ强脉冲光联合Medlite C6Q532nm激光治疗雀斑疗效好,不良反应少,值得临床推广。     

新型强脉冲光治疗面部雀斑的疗效观察

目的:观察新型强脉冲光治疗面部雀斑的临床疗效及安全性。方法:采用Lovel yerⅡ强脉冲光AFT 570～950nm,AFT 540～950nm,光斑面积16mm×40mm.脉宽10、12、15ms,能量密度14～19J/cm2,患者经3～5次治疗,两次治疗间隔时间3周,随访观察3～12个月。结果:21例雀斑患者经过治疗后10例(48%)基本完全消退,11例(52%)明显消退,总有效率100%。所有患者面部治疗区域皮肤较以前更光滑、细腻,未出现不良反应。结论:新型强脉冲光对雀斑的治疗,安全、有效,可以达到理想的治疗效果。     

强脉冲光治疗烧伤创面后色素沉着50例

目的:探讨强脉冲光治疗烧伤创面后色素沉着的临床效果.方法:回顾性分析我院z005年1月～2009年月12月强脉冲光技术治疗烧伤后色素沉着50例患者的临床资料.结果:本组50例患者,均经1疗程(4次)治疗,随访6个月,患者疗效治愈12例、显效18例、有效11例、无效9例,总有效率82.0%;元任何并发症发生.浅Ⅱ度烧伤30例总有效率90.0%高于深Ⅱ度烧伤20例的70.0%(P<0.05);41例总有效患者平均年龄(46.34±13.23)岁小于9例无效的(57.78±12.34)岁(P<0.05).结论:强脉冲光治疗烧伤创面后色素沉着的临床效果满意,值得临床应用.     

强脉冲光联合精确冷冻治疗雀斑临床观察

目的：评价强脉冲光联合精确冷冻治疗对面部雀斑的疗效及安全性。方法：84例雀斑患者，采用强脉冲光治疗,波长560～1200mm，光斑尺寸34mm×8mm，双脉冲脉宽4～5ms、3～4ms，脉冲延时20～30ms，能量密度24～32J/cm2，两次治疗间隔时间4周，共5次。2周后对患者上下眼睑进行精确冷冻治疗。结果：84例患者，治愈49例，显效33例，有效2例，总有效率100%，并且所有患者肤质变得更细腻光滑，紧致，富有弹性，未见明显不良反应，患者满意度高。结论：强脉冲光联合精确冷冻治疗面部雀斑，安全、疗效显著，不影响社交，值得临床推广应用。     

Q开关Nd:YAG1064nm激光联合强脉冲光治疗56例颧部褐青色痣临床疗效探讨

目的 观察Q 开关Nd:YAG1064nm激光与强脉冲光570～950nm 联合治疗颧部褐青色痣的临床疗效.方法 采用Q 开关Nd:YAG1064nm激光与强脉冲光570～950nm对56例颧部褐青色痣患者行联合治疗;每次治疗前根据皮损状况的不同,选用不同的治疗方式,不同的治疗参数;治疗间隔期积极采用促进色素代谢及组织修复等辅助疗法.结果 56例患者总有效率为100%.痊愈39例,显效13例,有效4例,无效0例..所有患者中Q开关激光治疗1次者18例,2次者31例,3次者7例.结论 Q 开关Nd:YAG1064nm激光与强脉冲光联合治疗颧部褐青色痣疗效可靠,且减少了炎症后色素沉着的发生率,缩短了治疗时间,患者满意度明显提高.     

Lovely Ⅱ强脉冲光治疗雀斑的疗效及安全性评价

目的:探讨飞顿LovelyⅡ强脉冲光治疗雀斑的临床疗效及安全性。方法:回顾性分析笔者科室收治的经飞顿LovelyⅡ强脉冲光治疗的260例雀斑患者临床资料。所有入选病例均完成了4次治疗,每次治疗间隔4周,并接受为期1年的随访。通过对比治疗前后照片进行图像分析随访患者的满意程度及出现的不良反应,综合评价其安全性和临床疗效。结果:260例雀斑患者经4次治疗后,总有效率100.0%,患者对治疗效果的满意率达96.9%。260例患者随访1年后,复发14例,复发率达5.4%,复发皮损均未超过原皮损的20%。无1例出现色素减退、色素沉着及瘢痕等不良反应。结论:LovelyⅡ强脉冲光治疗雀斑疗效好,安全性高。     

强脉冲光治疗皮肤色素性疾病的临床观察

目的光子嫩肤技术是用强脉冲光改善皮肤光老化的非剥脱治疗;对皮肤色素病有较好疗效.观察强脉冲光对颜面常见色素性皮肤病的短期疗效.方法应用强脉冲光对患者面部照射,治疗波长为560nm,治疗脉宽为2.4～6ms,每个光斑2～3脉冲,能量密度24～36J/cm2.每隔3周治疗一次,5～6次为一个疗程.每次治疗前采集皮损图像.按痊愈、显效、有效及无效4级做出评价.结果受治患者综合疗效有不同程度改善.色素性疾病中,雀斑和脂溢角化病的疗效最明显,毛细血管扩张也有显著疗效.其他色素病有不同程度消退.经半年以上随访未见复发.结论强脉冲光可治疗毛细血管扩张以及多种色素性皮肤损害,改善皮肤外观.其优势为无创伤,痛苦小,不影响工作.     

Q-开关Nd∶YAG激光联合强脉冲光治疗黄褐斑疗效分析

目的:探讨和评价Q-开关Nd:YAG激光联合强脉冲光(IPL)治疗黄褐斑的疗效和安全性。方法:将患者随机分为三组:Q-开关激光与强脉冲光联合治疗组:40例,先用Q-开关Nd:YAG激光治疗3次,再用强脉冲光治疗3次,间隔时间2个月;Q-开关激光治疗组:32例,采用Q-开关Nd:YAG(1064nm)激光治疗3次,间隔时间2个月;对照组:14例,采用中药祛斑面膜治疗,每周1次,连续4周1个疗程,总共完成6个疗程。所有患者治疗后防晒。结果:Q-开关激光与强脉冲光联合治疗组:治愈9例(22.50%),显效18例(45.0%),总有效率为67.50%;Q-开关激光治疗组:治愈4例(12.50%),显效13例(40.62%),总有效率为53.12%;对照组:治愈0例,显效2例(14.29%),总有效率为14.29%;Q-开关激光组与联合治疗组都取得了显著的疗效。联合治疗组色素沉着2例(5.0%),无增生性瘢痕;激光治疗组色素沉着3例(9.38%);对照组皮肤过敏1例(7.14%)。结论:Q-开关Nd:YAG激光联合强脉冲光(IPL)治疗黄褐斑安全、有效、副作用少,值得推广使用。     

强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑疗效观察

目的:观察强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑的临床效果。方法:选取笔者医院2017年5月-2019年5月收治的126例雀斑患者,随机分为观察组和对照组,每组63例。对照组采用强脉冲光治疗,观察组采用强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗,观察两组治疗后的临床效果。结果:观察组临床总有效率明显高于对照组(χ^2=12.86,P<0.01),观察组治疗总次数明显低于对照组(t=3.928,P<0.05),复发率也明显低于对照组(χ^2=4.189,P<0.05),患者对治疗满意度明显高于对照组(χ^2=13.945,P<0.01),两组不良反应发生率无明显差异(χ^2=0.099,P>0.05)。结论:强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗雀斑复发率低、治疗次数少、安全性高,临床效果显著,值得在临床上推广使用。     

Vbeam脉冲染料激光治疗皮肤葡萄酒色斑的疗效分析

目的 评价595 nm Vbeam脉冲染料激光治疗皮肤葡萄酒色斑(Pint wine stains,PWS)的临床疗效.方法 共114例PWS患者接受595 nm Vbeam脉冲染料激光治疗,脉宽3～10 ms,光斑直径7mm,能量密度10-15 J/cm2,动态冷却喷射30～40 ms,间隔10～30 ms,治疗间隔4～8周.根据皮损消退,将疗效分为4级:Ⅰ级为＞75%,Ⅱ级为50%～74%,Ⅲ级为25%～49%,Ⅳ级为＜25%.结果 114例经过1～10次治疗(平均5.9次),取得很好临床效果,其中Ⅰ级74例(64.9%),Ⅱ级29例(25.4%),Ⅲ级9例(7.9%),Ⅳ级2例(1.8%).并分析治疗次数、年龄大小、发生部位、颜色特点和疗效的关系,年龄小、发生于颈面部位、粉红型病损者疗效显著.随访6个月至2年,无复发,治疗部位无瘢痕形成.结论 595 nm波长Vbeam脉冲染料激光治疗皮肤PWS效果良好,并发症少,是目前一种很安全、较可靠的治疗方法.     

蜂巢皮秒激光联合强脉冲光治疗边缘不清型雀斑临床应用价值及安全性分析

目的 分析蜂巢皮秒激光联合强脉冲光治疗边缘不清型雀斑的临床应用价值。方法 选取2 0 2 2年 1月-12月我院收治的96例边缘不清型雀斑患者作为研究对象,采用随机数字表法将其分为A组、B组、 C组,每组32例。A组采用强脉冲光治疗,B组采用蜂巢皮秒激光治疗,C组采用蜂巢皮秒激光联合 强脉冲光治疗,比较三组治疗前后PSI评分、临床疗效及并发症发生率。结果 C组治疗后PSI评分低于 A组、B组（P ＜0.05）;C组总有效率为96.88%,高于B组的78.13%与A组的68.75%（P ＜0.05）;C组并发 症发生率为18.75%,低于B组的25.00%与A组的31.25%（P＜0.05）。结论 边缘不清型雀斑应用蜂巢皮秒激 光联合强脉冲光治疗可以改善患者面部雀斑症状,提高临床疗效,减少并发症发生率,具有应用价值。     

Intense Pulsed Light for the Treatment of Refractory Melasma in Asian Persons

BACKGROUND: Patients with dermal or mixed-type melasmas are often refractory to various treatments. Intense pulsed light has been used to treat melanocytic lesions with promising results. OBJECTIVE: The purpose of this study was to clarify the effectiveness of intense pulsed light for refractory melasma in Asian persons. METHODS: Seventeen patients were treated with intense pulsed light, during four sessions at 4-week intervals. The patients were also given 4% hydroquinone cream and broad-spectrum sunscreens to prevent and treat postinflammatory hyperpigmentation. Sixteen patients in the control group were treated with hydroquinone cream and sunscreens. The treatment efficacy was evaluated using reflectance spectrophotometer and patient satisfaction questionnaire. RESULTS: Patients in the intense pulsed light group achieved an average of 39.8% improvement in relative melanin index, compared to 11.6% improvement in the control group (p<0.05) at Week 16. Six (35%) patients in the intense pulsed light group had more than 50% improvement, compared to two (14%) patients in the control group. Two patients in the intense pulsed light group, however, experienced transient postinflammatory hyperpigmentation, and partial repigmentation was noted 24 weeks after the last treatment session. CONCLUSION: Intense pulsed light is a safe and effective treatment for refractory melasma in Asian persons, with minimal side effects. Further treatment sessions are required for maintenance therapy.     

长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光治疗增厚型微静脉畸形回顾性分析

目的：观察长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光治疗增厚型微静脉畸形的临床疗效和不良反应。方法：使用长脉冲1064nm Gentle YAG激光和595nm脉冲染料激光对14例患者进行治疗,其中长脉冲1064nm Gentle YAG激光能量密度150～240J/cm2,光斑直径3mm,脉宽20～40ms;595nm脉冲染料激光能量密度12～15J/cm2,光斑直径7mm,脉宽6～20ms;共治疗2～7次,间隔时间4～8周。结果：痊愈6例（6/14）,显效5例（5/14）,好转3例（3/14）,无效0例。治疗后出现轻度色素沉着3例（3/14）,均在数月后恢复,遗留增生性瘢痕1例（1/14）,凹陷性瘢痕1例（1/14）。结论：长脉冲1064nm Gentle YAG激光联合595nm脉冲染料激光是目前比较安全、高效的治疗增厚型微静脉畸形的方法。     

新型强脉冲光治疗寻常性痤疮临床观察

目的:观察应用新型强脉冲光治疗寻常性痤疮的疗效和安全性。方法:采用以色列Active OpticalSystems强脉冲光治疗系统(GEM专利技术的光子嫩肤仪)治疗50例寻常性痤疮患者1个疗程,观察和记录临床疗效及不良反应。结果:50例患者,基本痊愈12例(24%),显效28例(56%),总有效率80%。治疗后无皮肤红肿,色素沉着等不良反应。结论:新型强脉冲光治疗寻常性痤疮疗效显著,安全性高。     

Treatment of Port Wine Stains with Intense Pulsed Light: A Prospective Study

BACKGROUND: Recent studies have shown that intense pulsed light can be useful in treating port wine stains that were resistant to previous pulsed dye laser therapy. Asian persons with high epidermal melanin context can be at a higher risk of complication. OBJECTIVE: The aim of this study was to conduct a prospective trial to assess the efficacy and complication of intense pulsed light in the treatment of port wine stains in Chinese patients. METHODS: Twenty-two Chinese patients with port wine stains without previous treatment were recruited to receive intense pulsed light source therapy for five to seven treatments at intervals of 3 to 4 weeks. Patient demographics, skin type, characteristics of port wine stains including color and location, treatment parameters, degree of pain caused by intense pulsed light treatment, percentage of clearing, and treatment complications were recorded and entered into a database. A questionnaire was conducted to assess the influence of treatment on daily activity and the intensity of pain experienced during treatment. RESULTS: There were 17 female and 5 male patients. Their ages ranged from 6 to 45 years with a mean age of 21.8+/-10.1 years. More than 90% of patients had more than 25% of clearing and the majority of patients (50%) had 25% to 50% of clearing. Although 40% of the patients showed more than 50% clinical clearance, 9% of the patients were able to achieve more than 75% clearing. The only 2 patients with less than 25% clearing had nodular port wine stains and no patient was able to achieve complete clearing. The procedures were well tolerated with a mean pain score of 2.1+/-0.9 and the treatment had no influence on daily activity. One patient developed blisters and 6 patients had swelling for more than 24 hr that all resolved within 1 week without leaving permanent marks. They have been followed up from 12 to 27 months and there was no long-term complication. CONCLUSION: Intense pulsed light can be effective in treating port wine stains in Asian patients. In experienced hands, complications can be low and should be considered as one of the therapeutic options.     

强脉冲光联合Q开关532nm激光治疗面部皮肤光老化疗效观察

目的：探讨强脉冲光联合Q开关532nm激光治疗面部皮肤光老化的临床疗效。方法：将128例患者根据光老化皮肤损害的不同选择不同的波长及模式进行1个疗程（4～6次）的强脉冲光治疗,2周后使用Q开关532nm激光对疗效欠佳的皮损进行局部治疗,4周后进行疗效评价。结果：经过强脉冲光和激光联合治疗后,128例患者的光老化皮肤损害均有不同程度的改善,其中以毛细血管扩张、色素沉着、皮肤质地的改善最为明显,治疗的总有效率均达到90%以上,细小皱纹及毛孔粗大的总有效率也达到了73.81%、71.15%。结论：强脉冲光联合Q开关532nm激光治疗面部光老化,疗效可靠,并发症少,是一种理想的非侵入性治疗面部皮肤光老化的方法。