部分板层角膜移植治疗角膜皮样瘤疗效观察

目的评估部分角膜中央板层植片行移植术治疗角膜皮样瘤的疗效。方法2000~2005年,对20例角膜皮样瘤患者实施了部分板层角膜移植术治疗。结果复查初期和晚期的最佳矫正视力分别是0.2、0.6。术前≥6.0 D散光度数的患者术后散光度数显著减少。而术前散光度数<6.0 D的患者术后散光度数无明显改变。结论使用部分角膜中央板层植片行移植术治疗角膜皮样瘤能取得好的美容效果,且术后并发症少。     

板层角膜移植术治疗角膜皮样瘤的临床观察

目的 观察切除术联合板层角膜移植术治疗角膜皮样瘤的临床效果。方法 对切除术联合板层角膜移植术治疗角膜皮样瘤27例进行回顾性分析,观察术后排斥反应、治疗效果及并发症情况。结果 27例（27眼）手术后随访3～6月治愈率为100％。22例术后植片透明,愈合良好;4例出现假性翼状胬肉经自体角膜缘干细胞移植术后痊愈;1例出现植片下新生血管及植片水肿,经抗排斥治疗后完全恢复。结论 切除术联合板层角膜移植术是一种治疗角膜皮样瘤的有效方法。     

部分板层角巩膜移植术治疗角膜皮样瘤的疗效分析

目的:观察部分板层角巩膜移植术治疗角膜皮样瘤的疗效。方法:我们对15例角膜皮样瘤进行了部分板层角巩膜移植术。术后随访6mo～4a。结果:所有病例术后外观明显改善。15例15眼中14例14眼角膜植片透明。只有1例术后2wk出现排异反应经治疗植片恢复透明。结论:部分板层角巩膜移植术是目前治疗角膜皮样瘤的一种较理想的治疗方法。     

板层角膜移植治疗角膜缘皮样瘤临床分析

目的 评价板层角膜移植(lamellar keratoplasty,LKP)治疗角膜皮样瘤(limbal dermoids)的临床疗效.方法 对22例(22只眼,23处病变)行板层角膜移植治疗的角膜缘皮样瘤患者进行回顾性分析.随访3～48 个月(平均19个月).观察肿瘤治愈率,外观,植片透明度,视力变化及并发症.结果 肿瘤治愈率为100%.19/22例患者(20/23处病变)术后外观明显改善,植片透明.2/22例患者(2/23处病变)外观改善一般,植片轻度浑浊.1/22例患者(1/23处病变)术后发生排斥反应,外观改善差,植片灰白色混浊并见明显新生血管长入.术后最佳矫正视力等于或好于术前.结论 板层角膜移植术是治疗角膜皮样瘤的一种有效方法.早期手术,创伤小,术后反应轻.     

Goldenhar综合征二例

Goldenhar综合征又称眼-耳-脊柱发育不良综合征(oculo auricular vertebral dysplasia syndrome)，是一种少见的多发畸形，如眼、耳、下颌骨发育不全及脊柱畸形等，眼、耳异常最多见者为眼球迷牙瘤(choriostomas)及耳前悬垂物(preauriclr skintags)。1845年von-Arlt首例报道，国内报道不多，现将笔者收治的2例介绍如下。     

部分板层角巩膜移植术治疗角膜皮样瘤

目的：观察部分板层角巩膜移植术治疗角膜皮样瘤的疗效。方法：对17例角膜皮样瘤患者,用比瘤体直径大0．25mm的环钻划界,在病灶处做部分板层角膜及巩膜切除,在供体眼球相应部位钻取直径比植床大0．25mm的植片,行部分板层角巩膜移植术。术后随访4月－6月。结果：17例（17眼）中,15例（15眼）上皮光滑,植片透明。2例（2眼）术后3周出现层间新生血管,经抗排斥治疗后消退。无一例肿瘤复发。全部恢复正常眼表结构。结论：相应部位的部分板层角巩膜移植术是治疗角膜皮样瘤的较理想的方法。     

角膜皮样瘤的诊治方法及术后复发原因分析

目的 对角膜皮样瘤诊治方法及术后复发原因的初步探讨.方法 回顾性分析43例经病理证实的角膜皮样瘤的临床、病理资料.19例行皮样瘤切除术,2例行皮样瘤切除+结膜遮盖术,1例行皮样瘤切除+羊膜移植术,21例行皮样瘤切除+角膜板层移植术.结果 随访半年～6年,39例治愈,4例单纯行皮样瘤切除术复发,二次手术行板层角膜移植术,随访5年无复发.结论 治疗角膜皮样瘤应根据角膜受累程度采用不同的手术方式,相应部位的角膜皮样瘤切除联合板层角膜移植术可以减少术后复发的几率.     

板层角膜移植术治疗角膜病变

目的 探讨板层角膜移植术治疗角膜病变的疗效.方法 对16例(16眼)真菌性角膜溃疡、4例(4眼)角膜皮样瘤、3例(3眼)圆锥角膜患者行板层角膜移植术.结果 除2例(2眼)真菌性角膜溃疡术后复发改行部分穿透性角膜移植外,其余21例(21眼)手术均获成功.随访2个月～7a,21例植片均存活,角膜透明.14例(14眼)真菌性角膜溃疡患者矫正视力0.1～0.6;4例(4眼)角膜皮样瘤患者中2例层间出现少量新生血管,经抗排斥反应治疗后痊愈,无一例肿瘤复发;3例(3眼)圆锥角膜患者矫正视力0.3～0.5,未出现排斥反应,无复发.结论 板层角膜移植术是治疗多种角膜病变的有效术式.     

治疗性板层角膜移植疗效分析

本文报告采用新鲜鹅角膜、引产儿干燥角膜和尸体干燥角膜作治疗性板层角膜移植31例,结果满意。还重点讨论了鹅异种板层角膜移植和引产儿干燥角膜板层移植获得成功的机制等问题。     

板层角膜移植治疗角膜皮样肿

报告用板层角膜移植治疗角膜皮样肿53例.术后视力不变或提高占79.5%,下降占20.5%.12眼手术后角膜曲率测定:不变7眼,减少2眼,增加3眼,角膜散光不变或降低6眼,增加≤0.5D3眼,ID,1.5D和4.4D各一眼.7眼散瞳验光:术后散光不变3眼,减少2.5D,增加0.5D、1.0D和2.0D各一眼.并就手术指征和时机进行讨论.眼科学报1993;9:213—215。     

Lamellar keratoplasty with corneoscleral graft for limbal dermoids

To assess the postoperative outcomes of limbal dermoid excision with corneoscleral graft transplantation. The charts of 8 consecutive patients (mean age: 13.0y) who had undergone limbal dermoid excision with lamellar corneoscleral graft transplantation by a single surgeon were retrospectively reviewed. Mean dermoid size was 7.75 mm (6.0-12.0 mm). Mean visual acuities (in logMAR units) before and after surgery were 1.8 and 1.7, respectively (P=0.29). Spherical equivalents were 1.3 diopter (D) before surgery and 0.7 D after surgery (P=0.40). The mean astigmatism measurements before and after surgery were 2.4 D and 1.5 D, respectively (P=0.17). Vector analysis revealed a mild change in astigmatism with a mean “d” of 3.2 (0.56-6.89). No intra- or post-operative complications occurred. Lamellar keratoplasty for limbal dermoids is safe and offers good cosmesis and tectonic stability. A significant decrease in the amount of astigmatism is not expected following surgery.     

Phenotypic characterization of epibulbar dermoids

The purpose of this study was to characterize the phenotypic presentation, clinical course, and outcomes of epibulbar dermoids (EpDs) which are the most common congenital eye tumor in children. Sixty-eight dermoids were identified in 58 eyes of 48 patients of Seattle Children’s Hospital between 1981 and 2014 via electronic medical record search. Patients were organized into: “EpD-Only” [patients without other congenital anomalies (n = 13)], “EpD-CFM” [patients with a craniofacial microsomia (CFM) diagnosis (n = 25)], and “EpD-Other” [patients with other congenital anomalies (n = 10)]. All EpD in the EpD-Only group were unilateral and singular, while the EpD-CFM group had six cases with multiple unilateral EpD and five cases with bilateral EpD. In the EpD-Only group, 69 % of EpD were left sided, whereas in the EpD-CFM group, there was no side predisposition. Among both groups, the majority of EpD were limbal or lipodermoids in the inferotemporal quadrant of the eye. Surgery was more common and at a younger age in the EpD-CFM group than the EpD-Only group (56 vs. 38 %, 5.2 vs. 7.0 years). Follow-up surgeries occurred only in the EpD-CFM group (21 %). EpDs were most commonly associated with preauricular tags, congenital heart defects, genitourinary, and nervous system anomalies. Whereas the location and type of EpDs did not significantly differ between the groups, the phenotype in the EpD-Only group appears to be less complex. This may indicate an important difference between EpDs in isolation and those within CFM. Additional studies will further characterize these phenotypes and outcomes.