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1.
Background: The syndrome of deep dysphasia is characterised by an inability to repeat pseudowords and the production of semantic errors in word repetition. Several single case studies revealed that phonological decoding might be outstandingly impaired. Recovery of deep dysphasia has only been illustrated in detail for patient NC (Martin & Saffran, 1992 Martin, N. and Saffran, E. M. 1992. A computational account of deep dysphasia: Evidence from a single case study.. Brain and Language, 43: 240474. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Dell, Schwartz, Martin, Saffran, and Gagnon (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) tried to simulate NC's repetition performance in their connectionist lexical activation model, but it did not fit his error pattern as it assumes perfect recognition of auditory input.

Aims: In this new single case study on recovery of deep dysphasia, we intended to collect further evidence for the assumption that impaired input processing is the crucial cause of the impairment. Moreover, we aimed to explain impairment and psycholinguistic parameter effects in the connectionist semantic‐phonological model (Foygel & Dell, 2000 Foygel, D. and Dell, G. S. 2000. Models of impaired lexical access in speech production.. Journal of Memory and Language, 43: 182216. [Crossref], [Web of Science ®] [Google Scholar]) by adding a phonetic input level.

Methods & Procedures: JR's performance was repeatedly assessed in the course of recovery. Errors in naming and repetition were classified according to the taxonomy of Dell et al. (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). JR's error patterns were simulated in the semantic‐phonological model to determine the naming disorder and to predict word repetition. In addition, we established an error modality analysis to disentangle input and output impairments in repetition. Thus, the source of each error could be subclassified as belonging to either expressive or receptive components of repetition.

Outcomes & Results: Initially there was a sharp contrast between severely impaired word and pseudoword repetition and almost unimpaired reading aloud. During recovery, performance in naming and word repetition improved a great deal, while repetition of pseudowords remained impossible. The evolvement of real word repetition was characterised by psycholinguistic parameter effects at different points in time: concreteness before length, before frequency. The connectionist model over‐predicted correct responses in word repetition as for NC. There were only few expressive repetition errors; regarding receptive errors, nonwords and null responses decreased significantly while formal errors became the dominant error type in the course of recovery.

Conclusions: The development of psycholinguistic parameter effects, dissociations in performance, the computer simulations, and results from error modality analysis as well as changes of error pattern are ample evidence for the primary decoding disorder in JR. We argue that deep dysphasia can be explained by an impairment of phonetic–phonological connections in an extended version of the connectionist one‐route model of repetition with four rather than three levels of auditory word processing. The improved real word repetition despite persisting failure on pseudowords is accounted for by an increase of both phonetic–phonological and lexical–phonological connection weights.  相似文献   

2.
Prism Adaptation Therapy (PAT) is an intervention method in the treatment of the attention disorder neglect (Frassinetti, Angeli, Meneghello, Avanzi, & Ladavas, 2002 Frassinetti, F., Angeli, V., Meneghello, F., Avanzi, S. and Ladavas, E. 2002. Long-lasting amelioration of visuospatial neglect by prism adaptation. Brain, 125: 608623. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Rossetti et al., 1998 Rossetti, Y., Rode, G., Pisella, L., Farne, A., Li, L.Boisson, D. 1998. Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature, 395(6698): 166169. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The aim of this study was to investigate whether one session of PAT using a computer-attached touchscreen would produce similar after-effects to the conventional box normally used in PAT.

In four experiments, 81 healthy subjects and 7 brain-injured patients diagnosed with neglect were subjected to a single session of PAT under two conditions: (1) using the original box, and (2) using a computer-based implementation of PAT. The session of PAT included a pre-exposure step involving pointing at 30 targets without feedback; an exposure step involving pointing at 90 targets with prism goggles and feedback; and a post-exposure step involving pointing at 60 targets, with no goggles and no feedback.

The results indicate that the expected similarity in the after-effect produced by the two conditions seems to occur only if subjects receive feedback on pointing precision by seeing their fingertip during the exposure step. Attempts to provide feedback indirectly via icons on the computer screen failed to produce the expected size in the after-effect. The findings have direct implications for computer-based treatment of visuospatial disorders in the future and computer-assisted rehabilitation in general.  相似文献   

3.
Assistive technologies for cognition (ATC) provide an effective means to compensate for prospective memory failures among adults with acquired brain injury (ABI; de Joode, van Heugten, Verhey, & van Boxtel, 2010 de Joode, E., van Heugten, C., Verhey, F. and van Boxtel, M. 2010. Efficacy and usability of assistive technology for patients with cognitive deficits: A systematic review. Clinical Rehabilitation, 24: 701714. doi:10.1177/0269215510367551[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Sohlberg et al., 2007 Sohlberg, M. M., Kennedy, M., Avery, J., Coelho, C., Turkstra, L., Ylvisaker, M. and Yorkston, K. 2007. Evidence-based practice for the use of external aids as a memory compensation technique. Journal of Medical Speech-Language Pathology, 15(1): 1551.  [Google Scholar]). This study evaluated a novel ATC device, the Television Assisted Prompting (TAP) system, which provides audiovisual reminders at scheduled prospective times on a person's home television. A randomised, controlled crossover design evaluated task completion for two preferred, two non-preferred, and two structured experimental tasks among 23 adults with ABI between two conditions: TAP prompting or typical (TYP) practice, without TAP reminders. Main outcomes showed a significant advantage of prospective memory prompting (72% completion) over no prompting (43% completion) and higher task completion with TAP prompting for researcher-assigned experimental tasks (81%) compared to self-selected preferred (68%) or non-preferred (68%) tasks. Results are discussed in the context of ATC efficacy to support prospective memory prompting following ABI, with contributions and future directions for continued investigation of customisation of prompts to maximise task completion.  相似文献   

4.
This study was conducted to assess the psychometric properties of 2 assessment instruments, the Behavior Problems Inventory-01 (BPI-01; Rojahn, Matson, Lott, Esbensen, & Smalls, 2001 Rojahn, J., Matson, J. L., Lott, D., Esbensen, A. J. and Smalls, Y. 2001. The Behavior Problems Inventory: An instrument for the assessment of self-injury, stereotyped behavior, and aggressive/destructive behavior in individuals with developmental disabilities. Journal of Autism and Developmental Disorders, 31: 577588. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and the Nisonger Child Behavior Rating Form (NCBRF; Aman, Tassé, Rojahn, & Hammer, 1996 Aman, M. G., Tassé, M. J., Rojahn, J. and Hammer, D. 1996. The Nisonger CBRF: A child behavior rating form for children with developmental disabilities. Research in Developmental Disabilities, 17: 4157. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The sample consisted of 237 ethnically diverse children and adolescents with intellectual disabilities who ranged in age from 4 to 22 years. Reliability parameters included internal consistency, interteacher agreement, teacher-parent agreement, and test-retest reliability. Factorial validity was assessed first by bivariate Spearman rank (ρ) correlations and then by examining the factor structure fit via confirmatory factor analysis (CFA). Convergent and discriminant validity was assessed by multiple regression analyses across the 2 instruments. Reliability coefficients (internal consistency, interteacher agreement, and test-retest reliability) of the BPI-01 and of the NCBRF subscales ranged from fair to excellent and from poor to excellent, respectively. The CFA suggested a poor fit between the present and the original BPI-01 and NCBRF factor structures, although item-total correlations were reasonable. Convergent and discriminant validity between the BPI-01 and the NCBRF, however, was strong. Limitations of the study are discussed and recommendations for future studies are presented.  相似文献   

5.
The purpose of the present study was to examine depressive symptoms as a function of eating disorder (ED) diagnostic status and gender. A demographic questionnaire, the Beck Depression Inventory-II (BDI-II; Beck, Steer & Brown, 1996 Beck, A. T., Steer, R. A. and Brown, G. K. 1996. Manual for the Beck Depression Inventory, 2nd, San Antonio, TX: The Psychological Corporation.  [Google Scholar]), and the Questionnaire for Eating Disorder Diagnoses (Q-EDD; Mintz, O'Halloran, Mulholland & Schneider, 1997 Mintz, L. B., O'Halloran, M. S, Mulholland, A. M. and Schneider, P. A. 1997. Questionnaire for Eating Disorder Diagnoses: Reliability and validity of operationalizing DSM–IV criteria into a self-report format: Correction. Journal of Counseling Psychology, 44: 6379. [Crossref], [Web of Science ®] [Google Scholar]) were administered to a nonclinical sample of college-aged men (n = 115) and women (n = 136). Contrast tests revealed significant differences in mean BDI-II scores as a function of Q-EDD diagnostic status. This effect did not differ as a function of gender and the pattern was the same for both cognitive and somatic-affective depressive symptoms. The nature of the comorbid relationship between ED and depressive symptoms appears markedly similar across both genders.  相似文献   

6.
Recently, Kaiser (2003) Kaiser, J. 2003. Manganese: A high-octane dispute. Science, 300: 926928.  [Google Scholar] raised concerns over the increase in brain damage claims reportedly due to exposure to welding fumes. In the present article, we discuss methodological problems in conducting neuropsychological research on the effects of welding exposure, using a recent paper by Bowler et al. (2003) Bowler, R. M., Gysens, S., Diamond, E., Booty, A., Hartney, C. and Roels, H. A. 2003. Neuropsychological sequelae of exposure to welding fumes in a group of occupationally exposed men. International Journal of Hygiene & Environmental Health, 206: 517529. [Crossref], [PubMed], [Web of Science ®] [Google Scholar] as an example to illustrate problems common in the neurotoxicity literature. Our analysis highlights difficulties in conducting such quasi-experimental investigations, including subject selection bias, litigation effects on symptom report and neuropsychological test performance, response bias, and scientifically inadequate casual reasoning.  相似文献   

7.
Background: It has been argued that perseveration type corresponds to the level of breakdown, so that total perseveration (repetition of a whole word) involves reactivation of a previous word at the lexical level when the target word is insufficiently activated. A blended perseveration (repetition of part of a previous response) results from a failure of target activation at the phoneme level (e.g., Martin & Dell, 2007 Martin, N. and Dell, G. S. 2007. Common mechanisms underlying perseverative and non-perseverative sound and word substitutions. Aphasiology, 21(10/11): 10021017.  [Google Scholar]). This is challenged by the occurrence of nonword total perseverations, as these cannot be lexical retrievals (Hirsh, 1998 Hirsh, K. W. 1998. Perseveration and activation in aphasic speech production. Cognitive Neuropsychology, 15: 377388. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). A further problem is the occurrence of long intervals between perseverations and their sources. Some authors have invoked semantic relationships to explain these intervals (e.g., Martin, Roach, Brecher, & Lowery, 1998 Martin, N., Roach, A., Brecher, A. and Lowery, J. 1998. Lexical retrieval mechanisms underlying whole-word perseveration errors in anomic aphasia. Aphasiology, 12: 319333. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]).

Aims: This study examines the perseveration of two individuals with jargon aphasia and explores the proposal that while some perseveration may result from reactivation of recent responses as described above, others are built around default phonology, resulting in stereotypical errors.

Methods & Procedures: Tests of naming, reading, and repetition were administered. Responses were analysed to determine: the extent of perseveration; the occurrence of long intervals between perseverations and their sources; patterns of phoneme use; the occurrence of nonword total perseverations.

Outcomes & Results: Both individuals produced large numbers of perseverative responses. Perseverative responses following lengthy intervals could not be explained by semantic relationships. For each participant certain consonants were favoured and evidence was found of an interaction between the occurrence of perseveration and these favoured consonants. The possibility that word and nonword total perseverations arose from different sources was rejected because no difference was found in the use of the favoured phonemes in the two types.

Conclusions: The findings support the theory of two mechanisms for perseveration. The first is local, occurring when residual activation overrides incoming activation. This is confined to a single utterance and appears closely after the original occurrence. The second type is global, occurring across different contexts over time. It originates from default phonology when incoming activation is unavailable at the phoneme level. Both total and blended perseverations may result from this mechanism. Word total perseverations may be favoured because of feedback from the phoneme level to the lexical level. Ideas for future research and implications for intervention are discussed.  相似文献   

8.
Background: Production of passive sentences is often impaired in agrammatic aphasia and has been attributed both to an underlying structural impairment (e.g., Schwartz, Saffran, Fink, Myers, & Martin, 1994 Schwartz, M. F., Saffran, E. M., Fink, R. B., Myers, J. L. and Martin, N. 1994. Mapping therapy: A treatment program for agrammatism. Aphasiology, 8: 1954. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) and to a morphological deficit (e.g., Caplan & Hanna, 1998 Caplan, D. and Hanna, J. 1998. Sentence production by aphasic patients in a constrained task. Brain and Language, 63: 184218. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Faroqi-Shah & Thompson, 2003 Faroqi-Shah, Y. and Thompson, C. K. 2003. Effect of lexical cues on the production of active and passive sentences in Broca's and Wernicke's aphasia. Brain and Language, 85: 409426. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). However, the nature of the deficit in passive sentence production is not clear due to methodological issues present in previous studies.

Aims: This study examined active and passive sentence production in nine agrammatic aphasic speakers under conditions of structural priming using eyetracking to test whether structural impairments occur independently of morphological impairments and whether the underlying nature of error types is reflected in on-line measures, i.e., eye movements and speech onset latencies.

Methods & Procedures: Nine participants viewed and listened to a prime sentence in either active or passive voice, and then repeated it aloud. Next, a target picture appeared on the computer monitor and participants were instructed to describe it using the primed sentence structure.

Outcomes & Results: Participants made substantial errors in sentence structure, i.e., passives with role reversals (RRs) and actives-for-passives, but few errors in passive morphology. Longer gaze durations to the first-produced noun for passives with RRs as compared to correct passives were found before and during speech. For actives-for-passives, however, this pattern was found during speech, but not before speech.

Conclusions: The deficit in passive sentence production does not solely arise from a morphological deficit, rather it stems, at least in part, from a structural level impairment. The underlying nature of passives with RRs is qualitatively different from that of actives-for-passives, which cannot be clearly differentiated with off-line testing methodology.  相似文献   

9.
Background: Little research has been conducted on functional categories in probable Alzheimer's disease (pAD). Furthermore, the findings are contradictory, since some studies report ceiling performance on tense and/or subject–verb agreement (Kaprinis & Stavrakaki, 2007 Kaprinis, S. and Stavrakaki, S. 2007. Morphological and syntactic abilities in patients with Alzheimer's disease. Brain and Language, 103: 5960. doi:10.1016/j.bandl.2007.07.044[Crossref], [Web of Science ®] [Google Scholar]; Kavé & Levy, 2003 Kavé, G. and Levy, Y. 2003. Sensitivity to gender, person and tense inflection by persons with Alzheimer's disease. Brain and Language, 87: 267277. doi:10.1016/S0093-934X(03)00106-8[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), whereas others report morphosyntactic deficits and agrammatic profiles (e.g., Altmann, Kempler, & Andersen, 2001 Altmann, L. G. P., Kempler, D. and Andersen, E. S. 2001. Speech errors in Alzheimer's disease: Reevaluating morphosyntactic preservation. Journal of Speech, Language, and Hearing Research, 44: 10691082. doi:10.1044/1092-4388(2001/085)[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: This study investigates the ability of Greek-speaking pAD individuals to produce and judge subject–verb agreement, tense, and aspect. Given pAD individuals have working memory limitations (e.g., Baddeley, 1996 Baddeley, A. 1996. Exploring the central executive. The Quarterly Journal of Experimental Psychology, 49: 528. doi:10.1080/713755608[Taylor & Francis Online], [Web of Science ®] [Google Scholar]), and given the differential processing demands of agreement, tense and aspect (e.g., Fyndanis, Varlokosta, & Tsapkini, 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]), pAD participants are expected to perform better on agreement than on tense/aspect. Based on the hypothesis that reference to the past is computationally more demanding than reference to the future/present (e.g., Bastiaanse et al., 2011 Bastiaanse, R., Bamyaci, E., Hsu, C-J., Lee, J., Yarbay Duman, T. and Thompson, C. K. 2011. Time reference in agrammatic aphasia: A cross-linguistic study. Journal of Neurolinguistics, 24: 652673. doi:10.1016/j.jneuroling.2011.07.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), a within-tense dissociation is expected to emerge. Further, on the assumption that unmarked values of functional categories are less demanding than marked values (e.g., Lapointe, 1985 Lapointe, S. 1985. A theory of verb form use in the speech of agrammatic aphasics. Brain and Language, 24: 100155. doi:10.1016/0093-934X(85)90100-2[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), the imperfective (unmarked) aspect is expected to be better preserved than the perfective (marked) aspect.

Methods & Procedures: Ten Greek-speaking mild pAD individuals and six healthy controls participated in a sentence completion task, a grammaticality judgement task, and a sentence–picture matching task. Non-parametric tests were used for analysis of results.

Outcomes & Results: PAD participants were found to be significantly more impaired in aspect compared to tense and agreement, in both production and grammaticality judgement/comprehension. Agreement was found significantly better preserved than tense in production. Similar patterns of performance have been attested in agrammatism (e.g., Fyndanis et al., 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]). Reference to the past and reference to the future did not dissociate, whereas the imperfective aspect was found to be significantly more impaired than the perfective aspect in production.

Conclusions: PAD participants' better performance on producing agreement, compared to tense/aspect, is accounted for in terms of the differential demands these categories pose on the processing system. Agreement is computationally less demanding than tense/aspect, because the former involves processing of grammatical information only, whereas the latter involve processing and integration of grammatical and extralinguistic/conceptual information. The preponderance of tense over aspect is attributed to the subjectivity of the latter, which renders it either a category “difficult” to test, or a computationally more demanding condition. The results also show that reference to the past is as demanding as reference to the future. The hypothesis that unmarked values are easier than marked ones is not supported by our data.  相似文献   

10.
Background: Anagram and Copy Treatment (ACT) and Copy and Recall Treatment (CART) have been shown to improve written communication for those with severe aphasia (Beeson, 1999 Beeson, P. M. 1999. Treating acquired writing impairment: Strengthening graphemic representations. Aphasiology, 13: 767785. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]; Beeson, Hirsch, & Rewega, 2002 Beeson, P. M., Hirsch, F. M. and Rewega, M. A. 2002. Successful single-word writing treatment: Experimental analysis of four cases. Aphasiology, 16: 473491. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]; Beeson, Rising, & Volk, 2003 Beeson, P. M., Rising, K. and Volk, J. 2003. Writing treatment for severe aphasia: Who benefits?. Journal of Speech, Language, and Hearing Research, 46: 10381060. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). More recently, the addition of a spoken repetition component to the CART programme has been suggested to enhance oral naming in moderate aphasia (Beeson & Egnor, 2006 Beeson, P. M. and Egnor, H. 2006. Combining treatment for written and spoken naming. Journal of the International Neuropsychological Society, 12: 816827. [PubMed], [Web of Science ®] [Google Scholar]; Wright, Marshall, Wilson, & Page, 2008 Wright, H. H., Marshall, R. C., Wilson, K. B. and Page, J. L. 2008. Using a written cueing hierarchy to improve verbal naming in aphasia. Aphasiology, 22: 522536. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) and in cases with co-existing apraxia of speech (AOS) (de Riesthal, 2007 de Riesthal, M. Changes in written and spoken naming with a modified CART programme. Paper presented at the American Speech and Hearing Association. Boston, MA [Google Scholar]). No studies have investigated the use of a modified ACT and CART with spoken repetition in individuals with severe aphasia and AOS.

Aims: The purpose of the study was to examine ACT and CART modified with spoken naming repetition, using visual and auditory stimuli in the ACT sessions and home practice videos in the CART sessions, for individuals with severe aphasia.

Methods & Procedures: Three individuals, RC, AC, and MJ, with severe aphasia and coexisting AOS post left middle cerebral artery strokes participated in a 3-month programme. Participants were enrolled in modified ACT and CART with spoken repetition of the target word. For the CART programme a video was created for each word in a treatment set to facilitate repetition in the home practice programme. Probes of spoken and written performance were obtained at the onset of each session, and during baseline, treatment, and follow-up maintenance

Outcomes & Results: All participants improved in their ability to write the treatment stimuli. A 5-point scoring system (Helm-Estabrooks & Albert, 2003 Helm-Estabrooks, N. and Albert, M. L. 2003. Manual of Aphasia and Aphasia Therapy, Austin, TX: Pro-.  [Google Scholar]) was a more sensitive tool than the traditional binary scoring. None of the participants improved in the spoken naming condition with task stimuli. Mild improvement was noted in comparing pre- and post-test naming for MJ.

Conclusions: Our study supports evidence that ACT and CART may improve written naming skills in persons with severe aphasia. The inclusion of spoken repetition in the home practice CART programme may not be appropriate for cases with severe aphasia with AOS. However, further research using the technique with moderate aphasia with AOS may reveal that the technique of practice with auditory and visual stimuli is beneficial. The ease of using digital video tools with computer or augmentative devices has exciting and practical clinical application.  相似文献   

11.
12.
The Boston Naming Test (BNT) (Kaplan, Goodglass, & Weintraub, 1983 Kaplan, E., Goodglass, H., & Weintraub, S. (1983). The Boston Naming Test. Philadelphia, PA: Lea & Fibiger. [Google Scholar]) is the most commonly used test of confrontation naming in neuropsychology (Rabin, Barr, & Burton, 2005 Rabin, L., Barr, W., & Burton, L. (2005). Assessment practices of clinical neuropsychologists in the United States and Canada: A survey of INS, NAN, and APA Division 40 members. Archives of Clinical Neuropsychology, 20, 3365. doi:10.1016/j.acn.2004.02.005.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). However, there are significant criticisms of the BNT which suggest that it might not be the assessment measure of choice. These criticisms are that the BNT has poor psychometric properties, is not adequately standardized, and has inadequate norms. It is further suggested that when considered in the context of contemporary conceptualizations of the neuropsychology of naming, the BNT does not adequately capture the processes known to be required for successful naming, and does not sample widely enough from the content domain of “naming”. These criticisms suggest that the BNT is flawed as a measure of naming, and are discussed in detail in this review. Other stand-alone visual confrontation naming tasks are reviewed to evaluate whether any might be viable substitutes for the BNT in clinical neuropsychology. The Naming Test from the Neuropsychological Assessment Battery (Stern & White, 2009 Stern, R., & White, T. (2009). NAB Naming Test: Professional manual. Lutz, FL: Psychological Assessment Resources. [Google Scholar]) was identified as a possible alternative to the BNT, however, neither of these tests was designed with reference to models of the neuropsychology of naming, and development of a new test of naming is indicated.  相似文献   

13.
Background: A number of hypotheses have been formulated to account for comprehension data in agrammatic aphasia. They explain deficits in comprehending specific structures, such as semantically reversible non-canonical sentences, for example, Trace Deletion Hypothesis (TDH, Grodzinsky, 1986 Grodzinsky, Y. 1986. Language deficit and the theory of syntax. Brain and Language, 27: 135159. doi:10.1016/0093-934X(86)90009-X[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 1990 Grodzinsky, Y. 1990. Theoretical perspectives on language deficits, Cambridge, MA: MIT Press. [Crossref] [Google Scholar], 1995 Grodzinsky, Y. 1995. A restrictive theory of agrammatic comprehension. Brain and Language, 51: 2651. doi:10.1006/brln.1995.1039[Crossref], [Web of Science ®] [Google Scholar]), or functional categories, for example, Tree Pruning Hypothesis (TPH, e.g., Friedmann, 2006 Friedmann, N. 2006. Generalizations on variations in comprehension and production: A further source of variation and a possible account. Brain and Language, 96: 151153. doi:10.1016/j.bandl.2005.06.002[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Tense Underspecification Hypothesis (TUH, Wenzlaff & Clahsen, 2004 Wenzlaff, M. and Clahsen, H. 2004. Tense and agreement in German agrammatism. Brain and Language, 89: 5768. doi:10.1016/S0093-934X(03)00298-0[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 2005 Wenzlaff, M. and Clahsen, H. 2005. Finiteness and verb-second in German agrammatism. Brain and Language, 92: 3344. doi:10.1016/j.bandl.2004.05.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Interpretable Features’ Impairment Hypothesis (IFIH; e.g., Varlokosta et al., 2006 Varlokosta, S., Valeonti, N., Kakavoulia, M., Lazaridou, M., Economou, A. and Protopapas, A. 2006. The breakdown of functional categories in Greek aphasia: Evidence from agreement, tense, and aspect. Aphasiology, 20: 723743. doi:10.1080/02687030500513703[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Several studies, however, report evidence contradicting these theories (e.g., Caramazza, Capasso, Capitani, & Miceli, 2005 Caramazza, A., Capasso, R., Capitani, E. and Miceli, G. 2005. Patterns of comprehension performance in agrammatic Broca's aphasia: A test of the Trace Deletion Hypothesis. Brain and Language, 94: 4353. doi:10.1016/j.bandl.2004.11.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Dickey, Milman, & Thompson, 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and propose new accounts to explain the comprehension deficits in agrammatic aphasia, for example, Distributed Morphology Account (DMA, Dickey et al., 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: Against the background above, this study investigates the ability of three Greek-speaking agrammatic individuals to comprehend a wide range of structures and functional categories: semantically reversible (canonical) active and (non-canonical) passive sentences, Complementizer Phrase, subject-verb Agreement, Tense, and Aspect.

Methods & Procedures: We administered: (a) two sentence-picture matching tasks to test comprehension of reversible active and passive sentences, and Tense; (b) a sentence grammaticality judgement task to test judgement of Tense, Aspect, and subject-verb Agreement; and (c) a picture-pointing task to test comprehension of Complementizer Phrase.

Outcomes & Results: (a) Two of the three agrammatic participants performed at chance on reversible passive sentences and above chance on active sentences. The third participant performed equally high on the two sentence types. Two participants performed at chance on Tense comprehension and one above chance. (b) The three participants were selectively or across-the-board impaired in judgement of Agreement, Tense, and Aspect. One of the two selectively affected participants had chance performance on Aspect and above chance performance on Agreement and Tense. The other one performed at chance on Aspect and Tense, and above chance on Agreement. The third participant's performance was equally poor on all three categories. (c) All three agrammatic participants performed above chance on the comprehension of Complementizer Phrase.

Conclusions: In comprehension/judgement, canonical and non-canonical sentences do not dissociate in all agrammatic speakers, while functional categories associated with the verb morphology may be compromised in the face of relatively well-preserved categories that are located higher in the syntactic hierarchy. All three agrammatic participants support the DMA, and two of them support the TDH. Instead, none of them provided support to the TPH, TUH, and IFIH.  相似文献   

14.
We report normative data on topographical working memory collected through the Walking Corsi Test (WalCT; Piccardi et al., 2008 Piccardi, L. , Iaria, G. , Ricci, M. , Bianchini, F. , Zompanti, L. , & Guariglia, C. (2008). Walking in the Corsi test: Which type of memory do you need? Neuroscience Letters , 432 , 127131.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) for developing a standard administration procedure to be used in clinical and educational practice. A total of 268 typically developing Italian children aged 4–11 years performed both WalCT and Corsi Block-Tapping Test (CBT; Corsi, 1972 Corsi, P. M. (1972). Human memory and the medial temporal region of the brain . McGill University, Montreal: Unpublished doctoral dissertation. [Google Scholar]) a well-known visuo-spatial memory test. WalCT has already been validated in adults, demonstrating sensitivity in detecting topographical memory deficits even in individuals who have no other memory impairments. Our results showed that age, but not sex, affected performances. Both girls and boys had a larger span on the CBT than the WalCT. The youngest group did not differ in performing WalCT and CBT, but from 5.6 years of age children performed better on CBT than WalCT, suggesting that memory in reaching space develops before topographical memory. Only after 5 years of age do children learn to process specifically topographical stimuli, suggesting that this happens when their environmental knowledge becomes operational and they increase environmental independence. We also discuss the importance to introduce WalCT in the clinical assessment.  相似文献   

15.
Deep brain stimulation (DBS) now plays an important role in the treatment of Parkinson's disease, tremor, and dystonia. DBS may also have a role in the treatment of other disorders such as obsessive-compulsive disorder, Tourette's syndrome, and depression. The neuropsychologist plays a crucial role in patient selection, follow-up, and management of intra-operative and post-operative effects (Pillon, 2002 Pillon , B. ( 2002 ). Neuropsychological assessment for management of patients with deep brain stimulation . Movement Disorders , 17 ( Suppl 3 ), S116122 .[Crossref], [PubMed] [Google Scholar]; Saint-Cyr & Trepanier, 2000 Trepanier , L. L. , Kumar , R. , Lozano , A. M. , Lang , A. E. , & Saint-Cyr , J. A. ( 2000 ). Neuropsychological outcome of GPi pallidotomy and GPi or STN deep brain stimulation in Parkinson's disease . Brain and Cognition , 42 ( 3 ), 324347 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). There is now emerging evidence that DBS can induce mood, cognitive, and behavioral changes. These changes can have dramatic effects on patient outcome. There have been methodological problems with many of the studies of DBS on mood, cognition, and behavior. The neuropsychologist needs to be aware of these issues when following up patients, and constructing future studies. Additionally, this article will review all aspects of the DBS procedure that can result in mood, cognitive, and behavioral effects and what role(s) the neuropsychologist should play in screening and follow-up.  相似文献   

16.
A manual form of the Letter Memory Test (LMT: Orey, Cragar, & Berry, 2000 Orey , S. A. , Cragar , D. E. , & Berry , D. T. R. ( 2000 ). The effects of two motivational manipulations on the neuropsychological performance of mildly head-injured college students . Archives of Clinical Neuropsychology , 15 , 335348 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) was compared in neuropsychological evaluees classified as honest (HON: n = 39) or probable cognitive feigners (PCF: n = 10) using results from two well-validated motivational tests. With the exception of lower educational level and higher rate of compensation seeking in the PCF, the groups were equivalent on most important demographic and injury severity parameters. PCF participants scored significantly lower on most neuropsychological tests (median Cohen's d = 1.2), as well as on the manual LMT (Cohen's d = 4.2). Operating characteristics of the manual LMT in the present sample were comparable to those reported in a similar study using the computerized version of the LMT in neuropsychiatric patients (Vagnini et al., 2006 Vagnini , V. L. , Sollman , M. J. , Berry , D. T. R. , Granacher , R. P. , Clark , J. A. , et al. . ( 2006 ). Known-groups cross-validation of the Letter Memory Test in a sample of compensation-seeking mixed neurologic sample . The Clinical Neuropsychologist , 20 , 289304 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]).  相似文献   

17.
Background: One of the few studies to describe therapy specifically for phonological assembly difficulties in aphasia is a single-case study by Franklin, Buerk, and Howard (2002 Franklin, S., Buerk, F. and Howard, D. 2002. Generalised improvement in speech production for a subject with reproduction conduction aphasia. Aphasiology, 16(10/11): 10871114. [Taylor & Francis Online] [Google Scholar]). Their client made a significant improvement in picture naming for both treated and untreated words after therapy comprising two phases, the first aimed at improving auditory awareness and the second aimed at improving self-monitoring.

Aims: This study aimed to determine whether the treatment programme used by Franklin et al. (2002 Franklin, S., Buerk, F. and Howard, D. 2002. Generalised improvement in speech production for a subject with reproduction conduction aphasia. Aphasiology, 16(10/11): 10871114. [Taylor & Francis Online] [Google Scholar]) is replicable with other people with impaired phonological assembly as the main part of their aphasia, and to explore any differences in the outcomes for participants.

Methods & Procedures: A case series of four participants with aphasia with mixed impairments including phonological assembly difficulties received a replication of the treatment protocol described by Franklin et al. (2002 Franklin, S., Buerk, F. and Howard, D. 2002. Generalised improvement in speech production for a subject with reproduction conduction aphasia. Aphasiology, 16(10/11): 10871114. [Taylor & Francis Online] [Google Scholar]).

Outcomes & Results: None of the participants responded to therapy in the same way as Franklin et al.’s (2002 Franklin, S., Buerk, F. and Howard, D. 2002. Generalised improvement in speech production for a subject with reproduction conduction aphasia. Aphasiology, 16(10/11): 10871114. [Taylor & Francis Online] [Google Scholar]) original client. Three participants improved on naming after the first, auditory discrimination, phase of therapy, but only one participant made further gains in naming following the second, monitoring, phase of therapy, and all improvements seen were for treated items only. One participant did not show any significant improvement on naming of treated or untreated items after either phase of therapy.

Conclusions: Whereas Franklin et al.’s (2002 Franklin, S., Buerk, F. and Howard, D. 2002. Generalised improvement in speech production for a subject with reproduction conduction aphasia. Aphasiology, 16(10/11): 10871114. [Taylor & Francis Online] [Google Scholar]) original client had a relatively pure post-lexical phonological assembly impairment, the three participants in the current study whose speech improved after therapy had a combination of lexical and post-lexical phonological impairments, and it is proposed that their item-specific improvements in picture naming occurred as a result of improved mapping between semantics and the phonological output lexicon. The participant in this study whose speech did not improve following therapy had a combination of phonological assembly difficulties and apraxia of speech. This study demonstrates that the same therapy can work at different levels for different individuals, depending on many factors, including their profile of linguistic and cognitive impairments.  相似文献   

18.
Deficits in emotion recognition, a crucial aspect of social cognition, are common after serious brain injury, as are executive deficits. Since social cognition and executive function are considered to be separate constructs, our first aim was to examine the presence of emotion recognition problems in brain injury patients with dysexecutive problems. We studied 65 brain injury patients of mixed aetiology participating in a randomised controlled trial evaluating the effects of a multifaceted treatment for executive dysfunction (Spikman, Boelen, Lamberts, Brouwer, & Fasotti, 2010 Spikman, J. M., Boelen, D. H., Lamberts, K. F., Brouwer, W. H., & Fasotti, L. (2010). Effects of a multifaceted treatment program for executive dysfunction after acquired brain injury on indications of executive functioning in daily life. Journal of the International Neuropsychological Society, 16(1), 118129. doi: 10.1017/S1355617709991020[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and 84 matched controls with a test for emotion recognition. Results showed that, in patients with acquired brain injury exhibiting executive deficits, emotion recognition deficits are also present. Male patients are more impaired than female patients, irrespective of aetiology. Our second aim was to investigate whether emotion recognition problems negatively predict the results of the treatment programme. Pre-treatment emotion recognition performance significantly predicted resumption of roles in daily life (Role Resumption List; RRL) and performance on an ecologically valid test for everyday executive functioning (Executive Secretarial Task; EST) post-treatment and, in addition, interfered negatively with treatment condition. Moreover, worse pre-treatment emotion recognition skills affect the learning of compensatory strategies for executive dysfunction negatively, whereas pre-treatment dysexecutive deficits do not.  相似文献   

19.
Background: Semantic feature analysis (SFA) is a treatment for lexical retrieval impairment in which participants are cued to provide semantic information about concepts they have difficulty naming, in an effort to facilitate accurate lexical retrieval (Boyle, 2004a Boyle, M. 2004a. Discourse treatment for word retrieval impairment in chronic aphasia, Park City, UT: Presented at the Clinical Aphasiology Conference.  [Google Scholar]). Previous work has provided preliminary evidence that persons with aphasia who participated in SFA-focused group aphasia treatment demonstrate improved lexical retrieval in discourse, with additional improvements observed in either general communication informativeness or efficiency (Antonucci, 2009 Antonucci, S. M. 2009. Use of semantic feature analysis in group aphasia treatment. Aphasiology, 23(7–8): 854866. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Furthermore, results suggested that individuals with differing mechanisms of anomia could derive benefits from participation in SFA-focused group treatment.

Aims: The aim of the current study was to investigate further training of SFA in connected speech during group aphasia treatment. This study expanded and extended previous work (Antonucci, 2009 Antonucci, S. M. 2009. Use of semantic feature analysis in group aphasia treatment. Aphasiology, 23(7–8): 854866. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]), through the addition of participants with more varied aetiologies and severities of aphasia, and through the introduction of home practice. It was hypothesised that lexical retrieval during discourse would improve, as would overall communicative informativeness and/or efficiency.

Methods & Procedures: Four individuals with aphasia participated in biweekly group treatment during which SFA was trained through connected speech tasks. Three participants presented with stroke aphasia, while one demonstrated aphasia consequent to traumatic brain injury. Discourse measures included those for overall communicative informativeness and efficiency (Nicholas & Brookshire, 1993 Nicholas, L. E. and Brookshire, R. H. 1993. A system for quantifying the informativeness and efficiency of the connected speech of adults with aphasia. Journal of Speech & Hearing Research, 36(2): 338350. [PubMed] [Google Scholar]) and for word-class-specific lexical retrieval (Mayer & Murray, 2003 Mayer, J. F. and Murray, L. L. 2003. Functional measures of naming in aphasia: Word retrieval in confrontation naming versus connected speech. Aphasiology, 17(5): 481497. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Effect sizes were calculated for all discourse measures. Pre- and post-treatment performance on the spontaneous speech portion of the Western Aphasia Battery-Revised was also analysed relative to discourse measures, to corroborate findings from more frequently repeated probes.

Outcomes & Results: All four participants demonstrated improvement to communicative informativeness and/or efficiency in connected speech tasks.

Conclusions: Results provide additional support for the hypothesis that SFA administered during group aphasia treatment can be used successfully to facilitate improvement of communicative effectiveness. These results also support previous findings that individuals with differing aetiologies and natures of word retrieval impairment may benefit from participation in the same SFA-focused group aphasia treatment. Future work proceeding from this study may be directed towards differentiating which aspects of the treatment are most effective across participants with varied naming impairment, what is the optimal group composition and size, and towards discerning the most effective methods for facilitating and monitoring home practice.  相似文献   

20.
《Social neuroscience》2013,8(1):69-78
Abstract

Guided by influential models of face processing, efforts have been expended to uncover the neural substrates subserving the many facets of face perception. Extending this work, the present study used functional brain imaging (fMRI) to explore the relationship between the operations supporting the explicit extraction of sex and gaze-related information from faces. The brain imaging data showed the right superior temporal sulcus to be preferentially involved during assessments of gaze direction and a region of the left fusiform gyrus to be involved during sex categorization. These results provide support for the distributed face-processing model advanced by Haxby and colleagues (2000 Haxby, J. V., Hoffman, E. A. and Gobbini, I. M. 2000. The distributed human neural system for face perception. Trends in Cognitive Science, 4: 223233. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]).  相似文献   

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