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1.
ABSTRACT

We used factor analysis to examine relationships among tasks that have previously shown right hemispheric processing asymmetries. We were interested in whether processing emotion displayed by a face constitutes a distinct perceptual process from processing other facial characteristics. Interest in this topic arose after Boles [1991 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]. Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar](1 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), 59 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]91 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]] found evidence of a common process underlying face processing and then Boles [1992 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]. Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar](11 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), 963 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]988 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]] found evidence of a distinct process for the processing of the facial emotion. We used seven tasks that measured both face and non-face perception. Analysis of the asymmetries revealed measures from the five face tasks resulted in a single factor, thus failing to support the hypothesis that emotional face perception would involve a separate process from non-emotional face perception. A second factor revealed a separate process underlying enumeration, and a third factor revealed yet another process underlying line bisection. The results indicate that perceiving facial emotion results in right hemisphere processing, and faces as a whole are responsible for such processing.  相似文献   

2.
Background: Production of grammatical morphology is typically impaired in agrammatic aphasic individuals, as is their capacity to produce the syntactic structure responsible for licensing that morphology. Whether these two impairments are causally related has been an issue of long‐standing debate. If morphological deficits are a side‐effect of underlying syntactic ones, as has been claimed (Friedmann & Grodzinsky, 1997 Friedmann, N. and Grodzinsky, Y. 1997. Tense and agreement in agrammatic production: Pruning the syntactic tree.. Brain and Language, 56: 397425. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Izvorski & Ullman, 1999 Izvorski, R. and Ullman, M. 1999. Verb inflection and the hierarchy of functional categories in agrammatic anterior aphasia.. Brain and Language, 69: 288291.  [Google Scholar]), therapy that improves the syntactic deficit should remediate the morphological deficit as well. This paper reports a case study of one individual with such co‐occurring impairments and describes their recovery in response to linguistically motivated treatment targeting his syntactic deficits.

Methods & Procedures: MD is a 56‐year‐old male diagnosed with non‐fluent Broca's aphasia subsequent to a left‐hemisphere CVA, with limited capacity to produce syntactically complex utterances and grammatical morphology. He was enrolled in therapy using Treatment of Underlying Forms (TUF; Thompson & Shapiro, 2005 Thompson, C. K. and Shapiro, L. P. 2005. Treating agrammatic aphasia within a linguistic framework: Treatment of Underlying Forms.. Aphasiology, 19: 10211036. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]), targeting production of sentences involving Wh‐movement (object relative clauses). MD participated in twice‐weekly treatment sessions for approximately 2 months, with daily probes assessing his production of treated and untreated sentence types. In addition, probes assessing his grammatical morphology and sentence production were administered pre‐ and post‐treatment.

Outcomes & Results: Pre‐treatment scores in tests of grammatical morphology and sentence production indicated deficits in both domains. During treatment, MD successfully acquired production of a variety of sentences with Wh‐movement, although this did not generalise to sentences involving a grammatically distinct movement operation (NP‐movement). Post‐treatment scores also indicated a lack of improvement in production of grammatical morphology.

Conclusions: The dissociation between MD's morphological and syntactic recovery indicates that the recovery of syntactic and morphological processes in aphasia may occur independently in some individuals. The result would not be predicted by approaches in which morphological and syntactic impairments are strongly and causally related in aphasia, such as the tree‐pruning hypothesis (Friedmann, 2001 Friedmann, N. 2001. Agrammatism and the psychological reality of the syntactic tree.. Journal of Psycholinguistic Research, 30: 7188. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Friedmann & Grodzinsky, 1997 Friedmann, N. and Grodzinsky, Y. 1997. Tense and agreement in agrammatic production: Pruning the syntactic tree.. Brain and Language, 56: 397425. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Further, these results reinforce the conclusion that aphasia treatment can lead to generalisation, but only to linguistic material that is in a subset relation to trained structures (Thompson, Shapiro, Kiran, & Sobecks, 2003 Thompson, C. K., Shapiro, L. P., Kiran, S. and Sobecks, J. 2003. The role of syntactic complexity in treatment of sentence deficits in agrammatic aphasia: The complexity account of treatment efficacy (CATE).. Journal of Speech, Language, and Hearing Research, 46: 591607. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). This research was supported by the NIH under grant DC‐01948 to C. K. Thompson. The authors are grateful to Audrey Holland and two anonymous reviewers for their exceptionally helpful comments and suggestions. The authors are especially grateful to MD and his family for his participation in this research.   相似文献   

3.
Background: A number of hypotheses have been formulated to account for comprehension data in agrammatic aphasia. They explain deficits in comprehending specific structures, such as semantically reversible non-canonical sentences, for example, Trace Deletion Hypothesis (TDH, Grodzinsky, 1986 Grodzinsky, Y. 1986. Language deficit and the theory of syntax. Brain and Language, 27: 135159. doi:10.1016/0093-934X(86)90009-X[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 1990 Grodzinsky, Y. 1990. Theoretical perspectives on language deficits, Cambridge, MA: MIT Press. [Crossref] [Google Scholar], 1995 Grodzinsky, Y. 1995. A restrictive theory of agrammatic comprehension. Brain and Language, 51: 2651. doi:10.1006/brln.1995.1039[Crossref], [Web of Science ®] [Google Scholar]), or functional categories, for example, Tree Pruning Hypothesis (TPH, e.g., Friedmann, 2006 Friedmann, N. 2006. Generalizations on variations in comprehension and production: A further source of variation and a possible account. Brain and Language, 96: 151153. doi:10.1016/j.bandl.2005.06.002[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Tense Underspecification Hypothesis (TUH, Wenzlaff & Clahsen, 2004 Wenzlaff, M. and Clahsen, H. 2004. Tense and agreement in German agrammatism. Brain and Language, 89: 5768. doi:10.1016/S0093-934X(03)00298-0[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 2005 Wenzlaff, M. and Clahsen, H. 2005. Finiteness and verb-second in German agrammatism. Brain and Language, 92: 3344. doi:10.1016/j.bandl.2004.05.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Interpretable Features’ Impairment Hypothesis (IFIH; e.g., Varlokosta et al., 2006 Varlokosta, S., Valeonti, N., Kakavoulia, M., Lazaridou, M., Economou, A. and Protopapas, A. 2006. The breakdown of functional categories in Greek aphasia: Evidence from agreement, tense, and aspect. Aphasiology, 20: 723743. doi:10.1080/02687030500513703[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Several studies, however, report evidence contradicting these theories (e.g., Caramazza, Capasso, Capitani, & Miceli, 2005 Caramazza, A., Capasso, R., Capitani, E. and Miceli, G. 2005. Patterns of comprehension performance in agrammatic Broca's aphasia: A test of the Trace Deletion Hypothesis. Brain and Language, 94: 4353. doi:10.1016/j.bandl.2004.11.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Dickey, Milman, & Thompson, 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and propose new accounts to explain the comprehension deficits in agrammatic aphasia, for example, Distributed Morphology Account (DMA, Dickey et al., 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: Against the background above, this study investigates the ability of three Greek-speaking agrammatic individuals to comprehend a wide range of structures and functional categories: semantically reversible (canonical) active and (non-canonical) passive sentences, Complementizer Phrase, subject-verb Agreement, Tense, and Aspect.

Methods & Procedures: We administered: (a) two sentence-picture matching tasks to test comprehension of reversible active and passive sentences, and Tense; (b) a sentence grammaticality judgement task to test judgement of Tense, Aspect, and subject-verb Agreement; and (c) a picture-pointing task to test comprehension of Complementizer Phrase.

Outcomes & Results: (a) Two of the three agrammatic participants performed at chance on reversible passive sentences and above chance on active sentences. The third participant performed equally high on the two sentence types. Two participants performed at chance on Tense comprehension and one above chance. (b) The three participants were selectively or across-the-board impaired in judgement of Agreement, Tense, and Aspect. One of the two selectively affected participants had chance performance on Aspect and above chance performance on Agreement and Tense. The other one performed at chance on Aspect and Tense, and above chance on Agreement. The third participant's performance was equally poor on all three categories. (c) All three agrammatic participants performed above chance on the comprehension of Complementizer Phrase.

Conclusions: In comprehension/judgement, canonical and non-canonical sentences do not dissociate in all agrammatic speakers, while functional categories associated with the verb morphology may be compromised in the face of relatively well-preserved categories that are located higher in the syntactic hierarchy. All three agrammatic participants support the DMA, and two of them support the TDH. Instead, none of them provided support to the TPH, TUH, and IFIH.  相似文献   

4.
Background: The impairment underlying apraxia of speech (AOS) is usually attributed to the phonetic encoding stage of the speech production process, where speech motor programs are accessed (e.g., Code, 1998 Code, C. 1998. Major review: Models, theories and heuristics in apraxia of speech.. Clinical Linguistics and Phonetics, 12: 4765. [Crossref], [Web of Science ®] [Google Scholar]). At this processing stage, Levelt, Roelofs, and Meyer (1999 Levelt, W. J. M., Roelofs, A. and Meyer, A. S. 1999. A theory of lexical access in speech production.. Behavioral and Brain Sciences, 22: 175. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) postulate a store of motor patterns for frequently used syllables (“syllabary”). These syllable gestures are assumed to be holistically represented. However, the fact that syllable structure influences the error mechanism of AOS is in conflict with the assumption of holistic syllable gestures.

Aims: This study examined the assumption of holistic syllable‐sized motor programs in apraxia of speech by a learning paradigm. We investigated if training of phonologically simple syllables, which were derived from more complex target syllables, showed a generalisation effect on these target syllables. If the assumption of holistic syllable programs is appropriate, no generalisation effects are expected.

Methods & Procedures: A learning experiment was conducted with four patients with AOS. For each of 24 complex target syllables a set of 15 training syllables was derived by deleting one or two of the onset and/or coda consonants or by assimilating consonantal features. The learning trials comprised repetitions of the training syllables, block‐wise for each target syllable. To assess generalisation effects, segmental errors and disfluencies were counted and syllable durations were measured before and immediately after training, for the target syllables as well as for matched control syllables.

Outcomes & Results: In the patients as a group, the training resulted in significant and specific improvements on the complex target syllables. The strongest effect was found in RK, a patient with pure AOS. This patient additionally exhibited a significant reduction of target but not of control syllable durations.

Conclusions: In this learning study, patients with apraxia of speech showed specific generalisation effects from phonologically simple syllables to more complex syllables. These effects cannot be explained by the assumption of holistically stored syllable programs (Levelt et al., 1999 Levelt, W. J. M., Roelofs, A. and Meyer, A. S. 1999. A theory of lexical access in speech production.. Behavioral and Brain Sciences, 22: 175. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). In contrast, the results suggest that syllabic motor programs comprise an internal phonological structure.  相似文献   

5.
This paper examines the effects of a cueing hierarchy on naming in a patient with anomic aphasia. Using a single‐subject multiple baseline design across behaviors, the patient was trained to produce single inanimate nouns while generalization was tested to semantically related nouns matched for frequency of occurrence. Results showed successful acquisition and maintenance of trained words, but no generalization to untrained words. These data indicate that generalization does not occur as a natural by‐product of successful treatment and suggest, as pointed out by Baer, Wolf, and Risley (1968 Baer, D. M., Wolf, N. M. and Risley, T. R. 1968. Some current dimensions of applied behavior analysis.. Journal of Applied Behavior Analysis, 1: 91[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), that “generalization should be programmed rather than expected or lamented”.  相似文献   

6.
Executive functioning influences a host of other cognitive processes and people who attend neuropsychological services are more likely to display executive dysfunction than any other cognitive deficit (Stuss & Levine, 2002 Stuss, D. and Levine, B. 2002. Adult clinical neuropsychology: Lessons from studies of the frontal lobes. Annual Review of Psychology, 53: 401433. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Impairment in executive functioning disrupts a person's ability to effectively employ their intact areas of functioning, and undermines effective self-management of other areas of dysfunction, hampering attempts to employ compensatory strategies. Therefore, assessment of a person's executive functioning is a high priority as part of a comprehensive neurorehabilitation plan. Guided by the International Classification of Functioning, Disability, and Health model (ICF model; Peterson, 2005 Peterson, D. 2005. International Classification of Functioning, Disability and Health: An introduction for rehabilitation psychologists. Rehabilitation Psychology, 50: 105112. [Crossref], [Web of Science ®] [Google Scholar]), we suggest that an important development in the field is moving to formal assessment of executive performance in functional contexts, in addition to more traditional assessment of executive impairment. We outline a number of existing studies in this area, review current measures that can provide clinicians with useful information on these issues, and discuss how this research could be further advanced.  相似文献   

7.
Background: Both orthographic and phonological information from the target word can be appropriate cues in anomia treatment. Furthermore, both types of cues are used very frequently in clinical practice, although their underlying mechanisms of effectiveness and stability are still a matter of debate (e.g., Basso, Marangolo, Piras, & Galluzzi, 2001 Basso, A., Marangolo, P., Piras, F. and Galluzi, C. 2001. Acquisition of new “words” in normal participants: A suggestion for the treatment of anomia.. Brain and Language, 77: 4559. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Best, Herbert, Hickin, Osborne, & Howard, 2002 Best, W., Herbert, R., Hickin, J., Osborne, F. and Howard, D. 2002. Phonological and orthographic facilitation of word‐retrieval in aphasia: Immediate and delayed effects.. Aphasiology, 16: 151168. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]; Howard & Harding, 1998 Howard, D. and Harding, D. 1998. Self‐cueing of word retrieval by a woman with aphasia: Why a letter board works.. Aphasiology, 12: 399420. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]).

Aims: The aim of the study was to examine the mechanisms by which orthographic cues are effective in detail. The study addresses two questions. First, what is the relationship between sublexical transcoding ability and the effectiveness of orthographic cues? And second, what is the relationship between effectiveness of orthographic cues and effectiveness of phonological cues?

Methods & Procedures: Three people with chronic aphasia and moderate to severe anomia participated in facilitation of spoken naming, using either the initial phoneme or initial letter of the target word. Both immediate and delayed effects were assessed over six facilitation sessions. Orthographic and phonological cue effects were investigated with regard to regularity of orthographic‐phonological conversion (OPC) of the target's initial letter, and with regard to sub‐lexical and lexical reading and repetition in the participants using a multiple single‐case design (cf. Howard, 2003 Howard, D. 2003. “Single cases, group studies and case series in aphasia therapy.”. In The sciences of aphasia: From therapy to theory, Edited by: Papathanasiou, I and De Bleser, R. 245258. Oxford, , UK: Elsevier Science Ltd. [Crossref] [Google Scholar]).

Outcomes & Results: In one participant both phonological and orthographic cues produced similar effects. In the other two participants, orthographic cueing effects were present in the absence of phonological cueing effects. With regard to regularity of the initial letter‐phoneme conversion in the orthographic condition, a similar pattern overall was present for regular, ambiguous, and irregular target words, e.g., initial letter cues seemed to be similarly effective in words such as KNIFE (irregular OPC of initial letter) as in words such as KING or DOLL.

Conclusions: Initial letter cues are appropriate cues for the effective treatment of anomia as they may produce strong and long‐lasting effects. In contrast to earlier predictions (e.g., Bruce & Howard, 1988 Bruce, C. and Howard, D. 1988. Why don't Broca's aphasics cue themselves? An investigation of phonemic cueing and tip of the tongue information.. Neuropsychologia, 26: 253264. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]), initial letter cues may be effective even in participants where the initial phoneme cue remains totally ineffective. There are likely to be various mechanisms of effectiveness underpinning orthographic cue effects: a sub‐lexical mechanism and a lexical mechanism of effectiveness.  相似文献   

8.
Background: Working memory (WM) has gained recent attention as a cognitive construct that may account for language comprehension deficits in persons with aphasia (PWA) (Caspari, Parkinson, LaPointe, & Katz, 1998 Caspari, I., Parkinson, S. R., LaPointe, L. L. and Katz, R. C. 1998. Working memory and aphasia.. Brain and Cognition, 37: 205223. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Martin, Kohen, & Kalinyak‐Fliszar, 2008 Martin, N., Kohen, F. and Kalinyak‐Fliszar, M. 2008. A diagnostic battery to assess language and short‐term memory deficits in aphasia Poster presentation at Clinical Aphasiology Conference, Teton Village, WY [Google Scholar]; Wright, Downey, Gravier, Love, & Shapiro, 2007 Wright, H. H., Downey, R. A., Gravier, M., Love, T. and Shapiro, L. P. 2007. Processing distinct linguistic information types in working memory in aphasia.. Aphasiology, 21: 802813. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). However, few studies have investigated individual differences in performance on sentence comprehension tasks as a function of WM capacity in PWA when WM demands are manipulated.

Aims: The purposes of the current study were: (1) to examine the relationships among verbal WM, sentence comprehension, and severity of impairment in PWA and (2) to investigate the differential performance of high versus low verbal WM groups on sentence comprehension tasks in which task demands were manipulated by the length of the sentence stimuli, complexity of syntactic structure, and by presentation method which varied the time over which the linguistic material was available for computation.

Methods & Procedures: A total of 20 PWA were divided into high and low WM groups based on a listening version of a WM sentence span task. Each participant completed a listening version (CRTT) and three reading versions (CRTT‐R) of the Computerised Revised Token Test as the sentence comprehension tasks.

Outcomes & Results: The WM task significantly predicted performance on the CRTT conditions in which information was only temporarily available, thereby imposing greater WM demands on sentence comprehension. The verbal WM task was significantly correlated with aphasia severity and a principal components analysis revealed that the WM task, overall aphasia severity, and overall reading impairment level loaded on a single factor with 76% of shared variance. The low WM group's performance was significantly lower than the high WM group on the CRTT subtests with syntactically more complex structures and on the CRTT conditions with temporally restricted presentation methods.

Conclusions: This verbal WM task was significantly and moderately correlated with the overall severity of aphasia as well as with both listening and reading sentence comprehension. The WM group differences emerged only in sentence comprehension tasks with greater WM demands. These results are consistent with the notion that WM effects are most evident when WM capacity is sufficiently taxed by the task demands (e.g., Caplan & Waters, 1999 Caplan, D. and Waters, G. S. 1999. Verbal working memory and sentence comprehension.. Behavioral and Brain Sciences, 22: 77126. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Just & Carpenter, 1992 Just, M. A. and Carpenter, P. A. 1992. A capacity theory of comprehension: Individual differences in working memory.. Psychological Review, 99: 122149. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]).  相似文献   

9.
Background: The syndrome of deep dysphasia is characterised by an inability to repeat pseudowords and the production of semantic errors in word repetition. Several single case studies revealed that phonological decoding might be outstandingly impaired. Recovery of deep dysphasia has only been illustrated in detail for patient NC (Martin & Saffran, 1992 Martin, N. and Saffran, E. M. 1992. A computational account of deep dysphasia: Evidence from a single case study.. Brain and Language, 43: 240474. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Dell, Schwartz, Martin, Saffran, and Gagnon (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) tried to simulate NC's repetition performance in their connectionist lexical activation model, but it did not fit his error pattern as it assumes perfect recognition of auditory input.

Aims: In this new single case study on recovery of deep dysphasia, we intended to collect further evidence for the assumption that impaired input processing is the crucial cause of the impairment. Moreover, we aimed to explain impairment and psycholinguistic parameter effects in the connectionist semantic‐phonological model (Foygel & Dell, 2000 Foygel, D. and Dell, G. S. 2000. Models of impaired lexical access in speech production.. Journal of Memory and Language, 43: 182216. [Crossref], [Web of Science ®] [Google Scholar]) by adding a phonetic input level.

Methods & Procedures: JR's performance was repeatedly assessed in the course of recovery. Errors in naming and repetition were classified according to the taxonomy of Dell et al. (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). JR's error patterns were simulated in the semantic‐phonological model to determine the naming disorder and to predict word repetition. In addition, we established an error modality analysis to disentangle input and output impairments in repetition. Thus, the source of each error could be subclassified as belonging to either expressive or receptive components of repetition.

Outcomes & Results: Initially there was a sharp contrast between severely impaired word and pseudoword repetition and almost unimpaired reading aloud. During recovery, performance in naming and word repetition improved a great deal, while repetition of pseudowords remained impossible. The evolvement of real word repetition was characterised by psycholinguistic parameter effects at different points in time: concreteness before length, before frequency. The connectionist model over‐predicted correct responses in word repetition as for NC. There were only few expressive repetition errors; regarding receptive errors, nonwords and null responses decreased significantly while formal errors became the dominant error type in the course of recovery.

Conclusions: The development of psycholinguistic parameter effects, dissociations in performance, the computer simulations, and results from error modality analysis as well as changes of error pattern are ample evidence for the primary decoding disorder in JR. We argue that deep dysphasia can be explained by an impairment of phonetic–phonological connections in an extended version of the connectionist one‐route model of repetition with four rather than three levels of auditory word processing. The improved real word repetition despite persisting failure on pseudowords is accounted for by an increase of both phonetic–phonological and lexical–phonological connection weights.  相似文献   

10.
Deep brain stimulation (DBS) now plays an important role in the treatment of Parkinson's disease, tremor, and dystonia. DBS may also have a role in the treatment of other disorders such as obsessive-compulsive disorder, Tourette's syndrome, and depression. The neuropsychologist plays a crucial role in patient selection, follow-up, and management of intra-operative and post-operative effects (Pillon, 2002 Pillon , B. ( 2002 ). Neuropsychological assessment for management of patients with deep brain stimulation . Movement Disorders , 17 ( Suppl 3 ), S116122 .[Crossref], [PubMed] [Google Scholar]; Saint-Cyr & Trepanier, 2000 Trepanier , L. L. , Kumar , R. , Lozano , A. M. , Lang , A. E. , & Saint-Cyr , J. A. ( 2000 ). Neuropsychological outcome of GPi pallidotomy and GPi or STN deep brain stimulation in Parkinson's disease . Brain and Cognition , 42 ( 3 ), 324347 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). There is now emerging evidence that DBS can induce mood, cognitive, and behavioral changes. These changes can have dramatic effects on patient outcome. There have been methodological problems with many of the studies of DBS on mood, cognition, and behavior. The neuropsychologist needs to be aware of these issues when following up patients, and constructing future studies. Additionally, this article will review all aspects of the DBS procedure that can result in mood, cognitive, and behavioral effects and what role(s) the neuropsychologist should play in screening and follow-up.  相似文献   

11.
Attitudes toward suicide are often investigated by means of questionnaires, most of which are overly long or of low psychometric quality. Eskin's (2004 Eskin , M. ( 2004 ). The effects of religious versus secular education on suicide ideation and suicidal attitudes in adolescents in Turkey . Social Psychiatry and Psychiatric Epidemiology , 39 , 536542 . doi: 10.1007/s00127-004-0769-x [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) Attitudes Towards Suicide Scale is short and first investigations suggest good psychometric properties, but its factor structure has scarcely been explored. Hence, we examined this instrument by a data-analytic approach that combines Mokken scaling and confirmatory factor analysis (CFA). Results revealed 6 factors, of which 1 possessed only weak measurement properties. CFAs indicated only borderline fit of models found in prior research, but adequate fit for the scale structures revealed by Mokken scaling. Psychometric properties of these scales were satisfactory. Both the instrument as well as the methodological approach presented here can be recommended for further research.  相似文献   

12.
Prism adaptation can ameliorate some symptoms of left spatial neglect after right-hemisphere stroke. The mechanisms behind this remain unclear. Prism therapy may increase exploration towards the contralesional side, yet without improving perceptual awareness, as apparently for the left side of chimeric face stimuli (Ferber et al. 2003 Ferber, S, Danckert, J, Joanisse, M, Goltz, HC and Goodale, MA. 2003. Eye movements tell only half the story. Neurology, 60: 18269. [INFOTRIEVE][CSA][Crossref], [PubMed], [Web of Science ®] [Google Scholar]). However, other prism studies suggest that perceptual awareness might be improved (e.g., Maravita et al., 2003 Maravita, A, McNei, J, Malhotra, P and Greenwood, R. 2003. Husain M and Driver J Prism adaptation can improve contralesional tactile perception in neglect. Neurology, 60: 182931. [INFOTRIEVE][CSA][Crossref], [PubMed], [Web of Science ®] [Google Scholar]). We tested the impact of prism therapy on visual awareness for the left side of chimeric objects as well as chimeric faces, in three neglect patients. Prism therapy dramatically improved awareness for the identity of the left side of chimeric non-face objects, but had no effect on judging expressions for chimeric faces. The latter may thus be unique in showing no prism benefit.  相似文献   

13.
Prism Adaptation Therapy (PAT) is an intervention method in the treatment of the attention disorder neglect (Frassinetti, Angeli, Meneghello, Avanzi, & Ladavas, 2002 Frassinetti, F., Angeli, V., Meneghello, F., Avanzi, S. and Ladavas, E. 2002. Long-lasting amelioration of visuospatial neglect by prism adaptation. Brain, 125: 608623. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Rossetti et al., 1998 Rossetti, Y., Rode, G., Pisella, L., Farne, A., Li, L.Boisson, D. 1998. Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature, 395(6698): 166169. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The aim of this study was to investigate whether one session of PAT using a computer-attached touchscreen would produce similar after-effects to the conventional box normally used in PAT.

In four experiments, 81 healthy subjects and 7 brain-injured patients diagnosed with neglect were subjected to a single session of PAT under two conditions: (1) using the original box, and (2) using a computer-based implementation of PAT. The session of PAT included a pre-exposure step involving pointing at 30 targets without feedback; an exposure step involving pointing at 90 targets with prism goggles and feedback; and a post-exposure step involving pointing at 60 targets, with no goggles and no feedback.

The results indicate that the expected similarity in the after-effect produced by the two conditions seems to occur only if subjects receive feedback on pointing precision by seeing their fingertip during the exposure step. Attempts to provide feedback indirectly via icons on the computer screen failed to produce the expected size in the after-effect. The findings have direct implications for computer-based treatment of visuospatial disorders in the future and computer-assisted rehabilitation in general.  相似文献   

14.
Background: In addition to the canonical subject-verb-object (SVO) word order, German also allows for non-canonical order (OVS), and the case-marking system supports thematic role interpretation. Previous eye-tracking studies (Kamide et al., 2003 Kamide, Y., Scheepers, C. and Altmann, G. M. 2003. Integration of syntactic and semantic information in predictive processing: Cross-linguistic evidence from German and English. Journal of Psycholinguistics Research, 32: 3754. doi: 10.1023/A:1021933015362 [Google Scholar]; Knoeferle, 2007 Knoeferle, P. 2007. “Comparing the time-course of processing initially ambiguous and unambiguous German SVO/OVS sentences in depicted events”. In Eye movement research. A window on mind and brain, Edited by: van Gompel, R., Fischer, M., Murray, W. and Hill, R. 517531. Oxford, , UK/Amsterdam: Elsevier.  [Google Scholar]) have shown that unambiguous case information in non-canonical sentences is processed incrementally. For individuals with agrammatic aphasia, comprehension of non-canonical sentences is at chance level (Burchert et al., 2003 Burchert, F., De Bleser, R. and Sonntag, K. 2003. Does morphology make the difference? Agrammatic sentence comprehension in German. Brain and Language, 87: 323342. doi: 10.1016/S0093-934X(03)00132-9[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The trace deletion hypothesis (Grodzinsky 1995 Grodzinsky, Y. 1995. A restrictive theory of agrammatic comprehension. Brain and Language, 50: 2751. doi: 10.1006/brln.1995.1039[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 2000 Grodzinsky, Y. 2000. The neurology of syntax: Language use without Broca's area. Behavioral and Brain Sciences, 23: 171. doi: 10.1017/S0140525X00002399[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) claims that this is due to structural impairments in syntactic representations, which force the individual with aphasia (IWA) to apply a guessing strategy. However, recent studies investigating online sentence processing in aphasia (Caplan et al., 2007 Caplan, D., Waters, G., DeDe, G., Michaud, J. and Reddy, A. 2007. A study of syntactic processing in aphasia I: Behavioral (psycholinguistic) aspects. Brain and Language, 101: 103150. doi: 10.1016/j.bandl.2006.06.225[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Dickey et al., 2007 Dickey, M. W., Choy, J. J. and Thompson, C. K. 2007. Real-time comprehension of Wh-movement in aphasia: Evidence from eyetracking while listening. Brain and Language, 100: 122. doi: 10.1016/j.bandl.2006.06.004[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) found that divergences exist in IWAs' sentence-processing routines depending on whether they comprehended non-canonical sentences correctly or not, pointing rather to a processing deficit explanation.

Aims: The aim of the current study was to investigate agrammatic IWAs' online and offline sentence comprehension simultaneously in order to reveal what online sentence-processing strategies they rely on and how these differ from controls' processing routines. We further asked whether IWAs' offline chance performance for non-canonical sentences does indeed result from guessing.

Methods & Procedures: We used the visual-world paradigm and measured eye movements (as an index of online sentence processing) of controls (N?=?8) and individuals with aphasia (N?=?7) during a sentence–picture matching task. Additional offline measures were accuracy and reaction times.

Outcomes & Results: While the offline accuracy results corresponded to the pattern predicted by the TDH, IWAs' eye movements revealed systematic differences depending on the response accuracy.

Conclusions: These findings constitute evidence against attributing IWAs' chance performance for non-canonical structures to mere guessing. Instead, our results support processing deficit explanations and characterise the agrammatic parser as deterministic and inefficient: it is slowed down, affected by intermittent deficiencies in performing syntactic operations, and fails to compute reanalysis even when one is detected.  相似文献   

15.
Background: Little research has been conducted on functional categories in probable Alzheimer's disease (pAD). Furthermore, the findings are contradictory, since some studies report ceiling performance on tense and/or subject–verb agreement (Kaprinis & Stavrakaki, 2007 Kaprinis, S. and Stavrakaki, S. 2007. Morphological and syntactic abilities in patients with Alzheimer's disease. Brain and Language, 103: 5960. doi:10.1016/j.bandl.2007.07.044[Crossref], [Web of Science ®] [Google Scholar]; Kavé & Levy, 2003 Kavé, G. and Levy, Y. 2003. Sensitivity to gender, person and tense inflection by persons with Alzheimer's disease. Brain and Language, 87: 267277. doi:10.1016/S0093-934X(03)00106-8[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), whereas others report morphosyntactic deficits and agrammatic profiles (e.g., Altmann, Kempler, & Andersen, 2001 Altmann, L. G. P., Kempler, D. and Andersen, E. S. 2001. Speech errors in Alzheimer's disease: Reevaluating morphosyntactic preservation. Journal of Speech, Language, and Hearing Research, 44: 10691082. doi:10.1044/1092-4388(2001/085)[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: This study investigates the ability of Greek-speaking pAD individuals to produce and judge subject–verb agreement, tense, and aspect. Given pAD individuals have working memory limitations (e.g., Baddeley, 1996 Baddeley, A. 1996. Exploring the central executive. The Quarterly Journal of Experimental Psychology, 49: 528. doi:10.1080/713755608[Taylor & Francis Online], [Web of Science ®] [Google Scholar]), and given the differential processing demands of agreement, tense and aspect (e.g., Fyndanis, Varlokosta, & Tsapkini, 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]), pAD participants are expected to perform better on agreement than on tense/aspect. Based on the hypothesis that reference to the past is computationally more demanding than reference to the future/present (e.g., Bastiaanse et al., 2011 Bastiaanse, R., Bamyaci, E., Hsu, C-J., Lee, J., Yarbay Duman, T. and Thompson, C. K. 2011. Time reference in agrammatic aphasia: A cross-linguistic study. Journal of Neurolinguistics, 24: 652673. doi:10.1016/j.jneuroling.2011.07.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), a within-tense dissociation is expected to emerge. Further, on the assumption that unmarked values of functional categories are less demanding than marked values (e.g., Lapointe, 1985 Lapointe, S. 1985. A theory of verb form use in the speech of agrammatic aphasics. Brain and Language, 24: 100155. doi:10.1016/0093-934X(85)90100-2[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), the imperfective (unmarked) aspect is expected to be better preserved than the perfective (marked) aspect.

Methods & Procedures: Ten Greek-speaking mild pAD individuals and six healthy controls participated in a sentence completion task, a grammaticality judgement task, and a sentence–picture matching task. Non-parametric tests were used for analysis of results.

Outcomes & Results: PAD participants were found to be significantly more impaired in aspect compared to tense and agreement, in both production and grammaticality judgement/comprehension. Agreement was found significantly better preserved than tense in production. Similar patterns of performance have been attested in agrammatism (e.g., Fyndanis et al., 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]). Reference to the past and reference to the future did not dissociate, whereas the imperfective aspect was found to be significantly more impaired than the perfective aspect in production.

Conclusions: PAD participants' better performance on producing agreement, compared to tense/aspect, is accounted for in terms of the differential demands these categories pose on the processing system. Agreement is computationally less demanding than tense/aspect, because the former involves processing of grammatical information only, whereas the latter involve processing and integration of grammatical and extralinguistic/conceptual information. The preponderance of tense over aspect is attributed to the subjectivity of the latter, which renders it either a category “difficult” to test, or a computationally more demanding condition. The results also show that reference to the past is as demanding as reference to the future. The hypothesis that unmarked values are easier than marked ones is not supported by our data.  相似文献   

16.
《Social neuroscience》2013,8(1):69-78
Abstract

Guided by influential models of face processing, efforts have been expended to uncover the neural substrates subserving the many facets of face perception. Extending this work, the present study used functional brain imaging (fMRI) to explore the relationship between the operations supporting the explicit extraction of sex and gaze-related information from faces. The brain imaging data showed the right superior temporal sulcus to be preferentially involved during assessments of gaze direction and a region of the left fusiform gyrus to be involved during sex categorization. These results provide support for the distributed face-processing model advanced by Haxby and colleagues (2000 Haxby, J. V., Hoffman, E. A. and Gobbini, I. M. 2000. The distributed human neural system for face perception. Trends in Cognitive Science, 4: 223233. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]).  相似文献   

17.
The Halstead-Reitan Battery has been instrumental in the development of neuropsychological practice in the United States. Although Reitan administered both the Wechsler-Bellevue Intelligence Scale and Halstead's test battery when evaluating Halstead's theory of biologic intelligence, the relative sensitivity of each test battery to brain damage continues to be an area of controversy. Because Reitan did not perform direct parametric analysis to contrast group performances, we reanalyze Reitan's original validation data from both Halstead (Reitan, 1955 Reitan , R. M. ( 1955 ). The distribution according to age of a psychologic measure dependent upon organic brain functions . Journal of Gerontology , 10 , 338340 . [INFOTRIEVE] [CSA] [Crossref], [PubMed] [Google Scholar]) and Wechsler batteries (Reitan, 1959a Reitan , R. M. ( 1959a ). The comparative effects of brain damage on the Halstead impairment index and the Wechsler-Bellevue scale . Journal of Clinical Psychology , 15 , 281285 . [INFOTRIEVE] [CSA] [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and calculate effect sizes and probability levels using traditional parametric approaches. Eight of the 10 tests comprising Halstead's original Impairment Index, as well as the Impairment Index itself, statistically differentiated patients with unequivocal brain damage from controls. In addition, 13 of 14 Wechsler measures including Full-Scale IQ also differed statistically between groups (Brain Damage Full-Scale IQ = 96.2; Control Group Full Scale IQ = 112.6). We suggest that differences in the statistical properties of each battery (e.g., raw scores vs. standardized scores) likely contribute to classification characteristics including test sensitivity and specificity.  相似文献   

18.
Developing language treatments that not only improve trained items but also promote generalisation to untrained items is a major focus in aphasia research. This study is a replication and extension of previous work which found that training abstract words in a particular context-category promotes generalisation to concrete words but not vice versa (Kiran, Sandberg, & Abbott, 2009 Kiran, S., Sandberg, C., & Abbott, K. (2009). Treatment for lexical retrieval using abstract and concrete words in persons with aphasia: Effect of complexity. Aphasiology, 23, 835853. doi: 10.1080/02687030802588866[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Twelve persons with aphasia (five female) with varying types and degrees of severity participated in a generative naming treatment based on the Complexity Account of Treatment Efficacy (CATE; Thompson, Shapiro, Kiran, & Sobecks, 2003 Thompson, C., Shapiro, L., Kiran, S., & Sobecks, J. (2003). The role of syntactic complexity in treatment of sentence deficits in agrammatic aphasia: The Complexity Account of Treatment Efficacy (CATE). Journal of Speech, Language, and Hearing Research, 46, 591607. doi: 10.1044/1092-4388(2003/047)[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). All participants were trained to generate abstract words in a particular context-category by analysing the semantic features of the target words. Two other context-categories were used as controls. Ten of the twelve participants improved on the trained abstract words in the trained context-category. Eight of the ten participants who responded to treatment also generalised to concrete words in the same context-category. These results suggest that this treatment is both efficacious and efficient. We discuss possible mechanisms of training and generalisation effects.  相似文献   

19.
Abstract

This study addressed the question of exactly which aspects of spelling-sound consistency influence accuracy of reading aloud in surface dyslexic patients with semantic dementia. Oral reading data were obtained from twelve patients on three sets of words that varied in regularity (defined according to grapheme-phoneme correspondences) and consistency (defined according to the pronunciation of word body neighbours). The patients were less accurate for irregular/inconsistent words, which they commonly pronounced in line with sound-spelling regularities, as expected in surface dyslexia. They produced plausible but incorrect responses for some regular as well as many irregular words, suggesting that their reading performance was influenced by sound-spelling relationships not captured by grapheme-phoneme correspondences. On a set of items that varied consistency and regularity independently, the patients showed a large effect of regularity and a smaller but significant effect of consistency in reading aloud. In addition, there was a correlation between degree of semantic impairment and level of reading accuracy for inconsistent items. These findings are discussed in terms of two influential models of reading: the dual-route-cascaded model (Coltheart et al., 2001 Coltheart, M, Rastle, K, Perry, C, Langdon, R and Ziegler, J. 2001. DRC: A dual route cascaded model of visual word recognition and reading aloud. Psychological Review, 108: 20456. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and the triangle model (Plaut et al., 1996 Plaut, DC. 1997. Structure and function in the lexical system: Insights from distributed models of word reading and lexical decision. Language and Cognitive Processes, 12: 765805. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). It is argued that the triangle model provides a more straightforward account of the relationship between word comprehension and consistency effects in reading.  相似文献   

20.
Background: Speakers with agrammatic aphasia have greater difficulty producing unaccusative (float) compared to unergative (bark) verbs (Kegl, 1995 Kegl, J. 1995. Levels of representation and units of access relevant to agrammatism. Brain and Language, 50: 151200. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Lee & Thompson, 2004 Lee, M. and Thompson, C. K. 2004. Agrammatic aphasic production and comprehension of unaccusative verbs in sentence contexts. Journal of Neurolinguistics, 17: 315330. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Thompson, 2003 Thompson, C. K. 2003. Unaccusative verb production in agrammatic aphasia: The argument structure complexity hypothesis. Journal of Neurolinguistics, 16: 151167. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]), putatively because the former involve movement of the theme to the subject position from the post-verbal position, and are therefore more complex than the latter (Burzio, 1986 Burzio, L. 1986. Italian syntax, Reidel: Dordrecht. [Crossref] [Google Scholar]; Perlmutter, 1978 Perlmutter, D. 1978. “Impersonal passives and the unaccusative hypothesis”. In Papers from the Fifth Annual Meeting of the Berkeley Linguistics Society, 157189. University of California, Berkeley: Berkeley Linguistics Society.  [Google Scholar]). However, it is unclear if and how sentence production processes are affected by the linguistic distinction between these two types of verbs in normal and impaired speakers.

Aims: This study examined real-time production of sentences with unergative (the black dog is barking) vs unaccusative (the black tube is floating) verbs in healthy young speakers and individuals with agrammatic aphasia, using eyetracking.

Methods & Procedures: Participants' eye movements and speech were recorded while they produced a sentence using computer displayed written stimuli (e.g., black, dog, is barking).

Outcomes & Results: Both groups of speakers produced numerically fewer unaccusative sentences than unergative sentences. However, the eye movement data revealed significant differences in fixations between the adjective (black) vs the noun (tube) when producing unaccusatives, but not when producing unergatives for both groups. Interestingly, whereas healthy speakers showed this difference during speech, speakers with agrammatism showed this difference prior to speech onset.

Conclusions: These findings suggest that the human sentence production system differentially processes unaccusatives vs unergatives. This distinction is preserved in individuals with agrammatism; however, the time course of sentence planning appears to differ from healthy speakers (Lee & Thompson, 2010 Lee, J. and Thompson, C. K. 2010. Real-time production of verb arguments and adjuncts in normal and agrammatic speakers: An eyetracking study. Language and Cognitive Processes., First published on 16 July 2010 (iFirst) [Google Scholar]).  相似文献   

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