彩色多普勒超声引导治疗假性动脉瘤的临床价值

目的 探讨彩色多普勒超声引导治疗假性动脉瘤的临床价值.方法 9例假性动脉瘤行超声引导下瘤腔内注射凝血酶治疗,4例行超声引导下压迫修复治疗;并在术后1d、7d、30d超声复查,监测疗效.结果 9例患者超声引导下注射凝血酶,其中8例一次性给药治疗成功,另1例在治疗失败后即刻压迫载瘤血管近端,重复注射凝血酶成功;4例行超声引导下,压迫治疗一次性成功.上述病例无过敏反应、感染、出血及异位栓塞等并发症发生.方论 超声引导下注射凝血酶及压迫治疗假性动脉瘤,操作简单、安全、快速有效,是无创治疗假性动脉瘤的最佳方法.     

超声引导下凝血酶封闭治疗医源性股动脉假性动脉瘤的临床分析

目的评价超声引导下瘤腔内注射凝血酶在治疗医源性股动脉假性动脉瘤中的应用价值。方法在彩色多普勒超声引导下,采用20G穿刺针经皮穿刺,对20例经股动脉介入术后股动脉假性动脉瘤患者行瘤腔内注射凝血酶封闭,凝血酶浓度为200U/ml,总量均≤500U。结果20例患者均1次治疗成功,术中、术后无并发症发生,术后无复发。结论超声引导下凝血酶封闭治疗假性动脉瘤创伤小,操作简便,疗效确切,可作为神经介入术后假性动脉瘤的首选治疗方法。     

超声引导下凝血酶注射治疗假性动脉瘤的护理

目的 介绍超声引导下假腔内注射凝血酶对股动脉假性动脉瘤的治疗方法及护理要点。方法 对我科1999年9月至2003年4月行经皮冠状动脉介入术后并发股动脉假性动脉瘤的12例患行假腔内凝血酶注射治疗。结果 12例患均治疗成功,未见明显并发症。结论 超声引导下假腔内注射凝血酶治疗股动脉假性动脉瘤具有操作简单、快速、安全、耐受性好、疗效高、费用低廉、明显缩短患住院时间及未见明显不良反应等优点,值得推广。护理上应做好术中术后护理,加强并发症的观察,重视出院指导。     

超声在诊治医源性股动脉假性动脉瘤中的应用

目的评价超声对医源性股动脉假性动脉瘤的诊断价值及超声引导下压迫治疗假性动脉瘤、注射凝血酶治疗假性动脉瘤的疗效。方法应用二维超声、彩色多普勒、频谱多普勒对28例股动脉穿刺术后临床疑诊为股动脉假性动脉瘤的患者进行检查,并在超声引导下进行压迫治疗,治疗失败者改为局部瘤腔内注射凝血酶治疗。结果28例中彩超诊断假性动脉瘤25例,3例阴性患者经临床观察排除假性动脉瘤,彩超诊断与临床符合率100%。彩超引导下压迫治疗假性动脉瘤,24例治愈,1例失败后改为瘤腔内注射凝血酶治愈。结论超声能无创、敏感地诊断股动脉假性动脉瘤,超声引导下压迫是治疗假性动脉瘤的简便、安全、可靠的方法,失败者可进行注射凝血酶等其他手段治疗。     

超声引导下凝血酶注射治疗肝动脉化疗栓塞术后股动脉假性动脉瘤的临床观察

目的 评价超声引导下凝血酶注射治疗肝动脉化疗栓塞术后股动脉假性动脉瘤的有效性、安全性.方法 记录和分析肝动脉化疗栓塞术后股动脉假性动脉瘤的发生率.分析超声引导下瘤腔凝血酶注射治疗的成功率、不良反应发生率.结果 6379例次肝动脉化疗栓塞术后发生股动脉假性动脉瘤22例,发生率0.34％.FAP瘤体平均最大直径23.1 m...     

超声引导下注射凝血酶栓塞治疗医源性假性动脉瘤

目的　初步评价超声引导下瘤内注射凝血酶治疗医源性假性动脉瘤的价值。方法　采用 2 2 G或 2 0 G spinal细针穿刺 ,对 7例医源性假性动脉瘤患者行超声引导下瘤内注射凝血酶栓塞治疗 ,利用二维结合彩色多普勒观察瘤体内血栓形成情况 ,每次注入 5 0～ 70 U,凝血酶总用量不超过 5 0 0 U,直至血栓形成。术后注意监测患者全身状况和远段动脉搏动情况。结果　 7例患者均经一次栓塞即获得成功 ,凝血酶用量 110～ 4 5 0 U,血栓形成时间 1.5～ 2 .5 min,1例患者术后 30 min发生急性过敏反应 ,经抗过敏治疗后恢复。所有患者无动脉栓塞发生。结论　超声引导下注射凝血酶栓塞治疗假性动脉瘤安全有效、操作简便。     

彩色多普勒超声诊断股动脉假性动脉瘤及疗效监测

目的探讨彩色多普勒超声对股动脉假性动脉瘤诊断及监测治疗疗效的价值。方法经股动脉穿刺行冠状动脉介入术后发生股动脉假性动脉瘤23例,包括冠状动脉造影术后15例,冠状动脉支架置入术后8例,所有患者都用高频彩色多普勒超声诊断。在超声监控下,探头垂直加压压迫假性动脉瘤通道或破口直至内无血流通过。压迫失败后在超声引导下瘤腔内注射凝血酶,24h、1个月后复查超声。结果23例中有15例一次性压迫2h后假性动脉瘤瘤腔闭合;5例一次压迫2h后超声显示瘤腔明显变小,动脉与瘤腔仍有少许血流相通,再次压迫2h后瘤腔闭合;3例压迫2次失败后在超声引导下瘤腔内注射凝血酶,2例取得较满意的效果,1例经验不足失败。结论彩色多普勒超声诊断股动脉假性动脉瘤准确,简便,无创。且可在超声引导下行安全无创治疗。     

超声指导下冠状动脉介入术后股动脉假性动脉瘤的诊断和治疗

目的探讨超声指导下冠状动脉介入术后股动脉假性动脉瘤的发生原因、临床表现、诊断及治疗方法。方法采用超声引导下压迫修复的方法,失败的病例选择超声引导下注射凝血酶。结果经超声检查确诊冠状动脉介入术后股动脉假性动脉瘤的39例患者中有18例经压迫修复治愈,平均压迫时间（36．78±1．71）rain。21例经压迫修复失败后采用瘤腔内注射凝血酶治愈,平均瘤内血栓形成时间（0．33±0．06）min。所有患者均于修复后24h复查超声,证实假性动脉瘤已闭合。术后随诊半年,未见假性动脉瘤复发。结论冠状动脉介入术后引发股动脉假性动脉瘤,在超声引导下压迫修复和超声引导下行腔内注入凝血酶是安全有效的治疗方法。     

超声引导下局部压迫或注射凝血酶治疗动脉插管术后假性动脉瘤的临床应用

目的探讨彩色多普勒超声引导下压迫或注射治疗假性动脉瘤的方法及疗效评估。方法 在超声引导下对20例动脉插管术后所致股动脉及锁骨下动脉假性动脉瘤患者，行压迫及注射治疗。结果14例假性动脉瘤采用单纯压迫法治疗，成功率为86％(12／14)。2例锁骨下动脉假性动脉瘤瘤内注射医用吻合胶(OB胶)，1例闭合后动脉瘤处产生硬块，另1例形成远端动脉阻塞。4例注射凝血酶者治疗成功率为100％(4／4)。结论 超声引导下对动脉插管术后假性动脉瘤采用单纯压迫法或瘤内注射凝血酶治疗是简单、安全、有效的方法，而采用瘤内注射医用OB胶则可能产生并发症。     

超声引导下凝血酶注射法治疗股动脉假性动脉瘤对血液流变特性的影响

目的评价超声引导下凝血酶注射法治疗股动脉假性动脉瘤(pseudoaneurysm,PSA)的疗效及对血液流变特性的影响。方法冠状动脉介入诊治术后股动脉PSA患者16例,在超声引导下穿刺PSA瘤腔并注射200IU凝血酶行封闭治疗,所有病例均在治疗后24h和3～5d复查超声,并在注射凝血酶前及注射凝血酶后48h检测有关血液流变参数。结果11例患者在瘤囊内注入200IU凝血酶后瘤腔即刻闭合,5例患者动脉与瘤腔通道血流明显减弱,在超声引起下压迫5～10min闭合,治愈率100％,无并发症发生。所有病例24h及3～5d后复查无复发。注射凝血酶前后血液流变参数无显著差异。结论该法治疗PSA简便、安全、有效,且对机体血液流变特性无明显影响。     

Percutaneous ultrasonographically guided thrombin injection of iatrogenic pseudoaneurysms in unusual sites.

OBJECTIVES: To evaluate the effectiveness and safety of percutaneous ultrasonographically guided thrombin injection as treatment of unusually positioned and unusually large iatrogenic pseudoaneurysms. METHODS: Five patients with iatrogenic pseudoaneurysms were evaluated by color duplex ultrasonography. Two patients had additional digital angiography, and 2 had additional computed tomographic angiography. In 3 of the patients, large, painful iatrogenic pseudoaneurysms located proximal (2 patients) and distal (1 patient) to the arteriovenous hemodialysis fistulas had developed, most likely due to erroneous puncture of the arterial side (brachial artery) or venous side (cephalic vein) of the fistulas. An iatrogenic pseudoaneurysm of the anterior tibial artery had developed in the fourth patient after osteotomy of the fibula, and an iatrogenic pseudoaneurysm of the superficial femoral artery had developed in the fifth patient after erroneous puncture during venous transfemoral angiography. With a sterile technique and color duplex ultrasonographic guidance, a diluted solution of bovine thrombin was slowly injected directly into the iatrogenic pseudoaneurysms until cessation of blood flow was seen. Follow-up color duplex ultrasonography was performed 24 to 48 hours after the ultrasonographically guided thrombin injection. RESULTS: Four iatrogenic pseudoaneurysms were successfully thrombosed during 1 session. Two large iatrogenic pseudoaneurysms necessitated multiple repositions of the injecting needle and several injections of small amounts of thrombin into the residual patent lumen to induce complete thrombosis without an appreciable increase in the total thrombin dosage. Follow-up examinations revealed complete and persistent thrombosis without evidence of distal embolization. One iatrogenic pseudoaneurysm involving the cephalic vein, distal to an arteriovenous hemodialysis fistula, recurred after apparently successful initial thrombosis. CONCLUSIONS: Most iatrogenic pseudoaneurysms are amenable to ultrasonographically guided thrombin injection as long as they are imaged adequately by color duplex ultrasonography.     

超声引导下注射凝血酶治疗假性动脉瘤的临床应用研究

目的评价超声引导下注射凝血酶治疗医源性假性动脉瘤（pseudoaneurysm，PSA）的疗效。方法高频探头引导20G细针穿刺，对经股动脉穿刺介入诊治冠状动脉疾病术后的PSA患者30例，注射凝血酶栓塞治疗（UGTI），彩色超声动态观察瘤体内血栓形成情况，凝血酶总用量不超过200U，直至血栓形成；术后监测同侧远段动脉搏动和患者全身状况。结果30例行UGTI的医源性股动脉假性动脉瘤患者，瘤内血栓形成迅速，治愈率100％；所有患者无动脉栓塞发生。结论该法治疗PSA简便、安全、有效，可作为临床治疗PSA的首选方法。     

超声引导下压迫修复法与凝血酶注射法治疗假性动脉瘤的对比研究

目的 对比研究超声引导下压迫修复法(UGCR)与凝血酶注射法(UGTI)治疗假性动脉瘤的临床价值.方法 回顾性研究利用UGCR和UGTI治疗股动脉假性动脉瘤的患者共63例,观察治疗成功时间和注射凝血酶的剂量.结果 38例行UGCR,治疗成功31例,治愈率81.5%;治疗时间8～120min,平均47min;25例患者行UGTI,瘤内血栓形成迅速,凝血酶用量为80～690 U,平均260 U;治疗时间为20～30 min,治愈率100%.结论 UGTI较UCCR治疗假性动脉瘤操作简便、临床效果可靠、并发症少、复发率低及患者痛苦少等优点,易于推广.     

Lower extremity arterial thrombosis following sonographically guided thrombin injection of a femoral pseudoaneurysm

Sonographically guided percutaneous thrombin injection is a minimally invasive and highly successful treatment of arterial pseudoaneurysms. Despite a very low complication rate, several severe arterial thrombotic events have been reported following thrombin injection of pseudoaneurysms. Native arterial thrombosis, though recognized as a severe complication of thrombin injection, has not been well described in the literature. We report a case of successful surgical management of arterial thrombosis after percutaneous thrombin injection of a femoral artery pseudoaneurysm in a 69-year-old woman. The pathophysiology, risk factors, diagnosis, and treatment options for this complication are discussed.     

Imaging-guided percutaneous thrombin injection for the treatment of iatrogenic femoral artery pseudoaneurysms

Abdominal Radiology - To evaluate factors that may affect successful ultrasound-guided percutaneous thrombin injection of iatrogenic femoral artery pseudoaneurysms (PSA). This was an IRB-approved,...     

Diagnosis and treatment of iatrogenic femoral artery pseudoaneurysms

Color Doppler is the procedure of choice for the diagnosis of iatrogenic femoral artery pseudoaneurysms. Although surgery is still necessary in a limited number of patients, most can be treated with ultrasound-guided thrombin injection. Success exceeds 90% and complications are much lower than surgery. Although rare, the major complication is embolization into the femoral artery. This can be minimized by using as little thrombin as possible, and by avoiding small pseudoaneurysms with short necks.     

Ultrasound‐guided thrombin injection in the treatment of iatrogenic arterial pseudoaneurysms: Single‐center experience

The aim of this study was to assess the safety and efficacy of ultrasound‐guided percutaneous thrombin injection for the treatment of postcatheterization arterial pseudoaneurysms. We evaluated retrospectively 82 consecutive subjects treated with percutaneous ultrasound‐guided thrombin injection of postcatheterization femoral (n = 79), brachial (n = 2), and radial (n = 1) pseudoaneurysms from January 2006 to April 2012. Pseudoaneurysm size, thrombin dose, and therapy outcome were documented. All pseudoaneurysm sacs were thrombosed with a single injection. The overall primary success rate (complete sac thrombosis) was 92.7%. A 30‐day Doppler ultrasound follow‐up showed a 100% procedural success. There were no complications. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 42 :24–26, 2014